Spatial Distribution of Tsetse Flies and Trypanosome Infection Status in a Vector Genetic Transition Zone in Northern Uganda by Robert Opiro, Okello Allele Moses, Robert Opoke, Francis A. Oloya, Esther Nakafu, Teresa Iwiru, Richard Echodu, Geoffrey M. Malinga, Joel L. Bargul, Elizabeth A. Opiyo

“…Tsetse flies are vectors of the genus Trypanosoma that cause African trypanosomiasis, a serious parasitic disease of people and animals. Reliable data on the vector distribution and the trypanosome species they carry is pertinent for planning sustainable control strategies. …”
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A1, an innovative fluorinated CXCR4 inhibitor, redefines the therapeutic landscape in colorectal cancer by Hossein Khorramdelazad, Kowsar Bagherzadeh, Ali Rahimi, Ali Darehkordi, Alireza Najafi, Milad Karimi, Majid Khoshmirsafa, Gholamhossein Hassanshahi, Elaheh Safari, Reza Falak

“…Following the development of the CRC animal model in BALB/c mice, immune system responses within the tumor microenvironment (TME) were evaluated. …”
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Shaoyao Gancao decoction alleviates paclitaxel-induced cognitive impairment by activating PTEN/PI3K/AKT pathway to inhibit NETs formation by Xu Ying, Su Yue, Hu Yuwen, Li Xiang, Zhou Ziyan, Yuan Ningning, Ji Xiaowei, Jiang Ruoyu, Wang Wenzhu, Zhang Yafeng, Zhai Guojie, Cheng Xiaolan

“…Herein, our work was set out to study the potential role and possible mechanism of SGD in PICI through network pharmacology, Mendelian analysis and animal experiments. Methods: First, network pharmacology analysis was performed to identify the potential active compounds and targets of SGD on PICI. …”
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Related Pentacyclic Triterpenes Have Immunomodulatory Activity in Chronic Experimental Visceral Leishmaniasis by Jéssica Adriana de Jesus, Márcia Dalastra Laurenti, Leila Antonangelo, Caroline Silvério Faria, João Henrique Ghilardi Lago, Luiz Felipe Domingues Passero

“…Studies of toxicity in golden hamster showed that Lu did not alter blood biochemical parameters associated with liver and kidney functions; however, a slight increase of aspartate aminotransferase level in animals treated with 2.5 mg/kg of UA was detected. …”
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Evaluation of multidrug resistance in the Gram-negative microbiome of cancer patients and the adverse effects of their metabolites on albino rats and epithelial or fibroblasts cell... by Mervat Morsy Abbas Ahmed El-Gendy, Huda Ahmed Alghamdi, Khaled G. Abdel-Wahhab, Nabila S. Hassan, Aya A. M. El-Bondkly, Mohammed Abdel-Wahab, Ayman A. Farghaly, Ahmed Mohamed Ahmed El-Bondkly

“…Conclusion These bacterial strains isolated from the cancer microbiome may play significant roles in inducing cancer, inflammation, mutagenesis, hepatotoxicity, nephrotoxicity, and sperm abnormalities, along with histopathological changes in the treated animal groups by orally administrated metabolites in compared to the untreated group. …”
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Comprehensive Analysis and Functional Characteristics of Differential Expression of N6-Methyladenosine Methylation Modification in the Whole Transcriptome of Rheumatoid Arthritis by Lei Wan, Jian Liu, Chuanbing Huang, Ziheng Zhu, Kun Wang, Guanghan Sun, Lei Zhu, Zhongxiang Hu

“…RA markers are such as rheumatoid factor (RF) and peptide containing citrulline (CCP). Further animal experiments showed that the expression of synovial MAPK, PI3K, and Akt1 proteins in the RA model was increased, and the PTEN, p-PTEN protein expression was decreased. …”
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A unique Helicobacter pylori strain to study gastric cancer development by Jeannette M. Whitmire, Ian H. Windham, Morris O. Makobongo, Mandy D. Westland, Sirena C. Tran, Jaume Piñol, Yvonne Hui, Rasha Raheem Alkarkoushi, Oscar Q. Pich, David J. McGee, M. Blanca Piazuelo, Angela Melton-Celsa, Traci L. Testerman, Timothy L. Cover, D. Scott Merrell

“…The USU101 strain reproducibly colonized Mongolian gerbils and induced gastric inflammation in the majority of the animals 1 month after infection. Adenocarcinoma or dysplasia was observed in the majority of gerbils by 2 months post-infection. …”
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The Effect of Rosuvastatin on a murine model of deep vein thrombosis by Megan E. Barney, Shenghao Zhou, Anh Le-Cook, Naly Setthavongsack, Gabriel Nager, Jennifer M. Loftis, Randy L. Woltjer, Monica Hinds, Khanh P. Nguyen

“…There was a significant increase in collagen deposition seen both in the thrombus (2.00 ± 0.63 vs 0.75 ± 0.46, p = 0.002) and vein wall (2.33 ± 0.82 vs 1.13 ± 0.35 p = 0.008) on day 7 in the rosuvastatin treated animals compared to the control animals. Conclusions: After DVT, rosuvastatin did not accelerate thrombus resolution nor did it affect thrombus formation. …”
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Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail by Rongbing Shu, Zhuanyi Yu, Jianmin Wu, Qiuxin Cheng, Zhihao Peng, Huaqiang Zhou, Min Zhao

“…WB was employed to detect the expression of Id-1, Snail, and epithelial-mesenchymal transition (EMT)-related proteins (E-cadherin, vimentin, and N-cadherin) in the OS cells of each group. In animal experiments, Tumor formation in each group was evaluated by injecting cells subcutaneously into mice. …”
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A leap forward: exploring the advantages of single-step genome evaluation in Italian Mediterranean buffalo by Stefano Biffani, Mayra Gómez, Roberta Cimmino, Dario Rossi, Gianluigi Zullo, Riccardo Negrini, Alberto Cesarani, Giuseppe Campanile, Gianluca Neglia

“…Data were analysed fitting two multitrait animal models, a 6-trait model for production data and a 2-trait model for morphology data. …”
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Determination of Seroprevalence and Risk Factors of Crimean–Congo Haemorrhagic Fever (CCHF) in the Endemic Region in Turkey: A Population-Based Cross-Sectional Study by Rıza Çıtıl, Mücahit Eğri, Yalçın Önder, Fazilet Duygu, Yunus Emre Bulut, Özkan Yaşayancan, Nagehan Yıldız Çeltek, Şafak Şahin

“…Male gender, advanced age group, low-educated, low-income, farmers, animal husbandry, and history of tick contact were found to be risk factors for CCHF. …”
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Nutritional Innovation Using Green Seaweed (Ulva sp.) and Garlic Powder Extracts for White‐Leg Shrimp (Litopenaeus vannamei) Challenged by Vibrio harveyi by Nashwa Abdel‐Razek, Riad H. Khalil, Abeer A. M. Afifi, Afrah F. Alkhuriji, Dina M. Metwally

“…The animals were fed ad libitum on the experimental diets up to satiety four times daily for 60 days. …”
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Evaluating the health risk of probiotic supplements from the perspective of antimicrobial resistance by Qiwen Tian, Hailv Ye, Xuan Zhou, Junyi Wang, Lifang Zhang, Wenxuan Sun, Chenxin Duan, Minyu Fan, Wei Zhou, Chuyun Bi, Qiong Ye, Aloysius Wong

“…Our data build the foundation for future studies that will be conducted on animal models and in humans and leveraging advanced metagenomics approaches to clarify the long-term health risk of probiotic consumption.…”
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Premalignant features of the prostate can be ameliorated by Uvaria chamae root extract: Modeling prostate cancer with cadmium and alternative treatment option in adult Wistar rats by Edem GD, Sakpa CL, Ezeuko VC

“…They were randomly divided into 10 groups of 6 animals per group (n=6). Group 1 received water and diet alone, group 2 received 3mg/kg of cadmium alone once weekly for 28days. …”
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Alterations in the polarization of liver M1/M2 macrophages upon long-term administration of triptorelin in rats by M.V. Rud, Y.V. Stetsuk, V.I. Shepitko, O.V. Vilkhova, L.B. Pelypenko, O.V. Voloshyna, A.G. Sydorenko, H.P. Pavlenko, N.M. Sharlai, O.V. Sych

“…Results. In the livers of animals on day 30 of the experiment, the number of CD68+ cells were calculated to be 12.2400 ± 1.5792 per FOV at p < 0.01, which is 2.2 times higher than in the control group. …”
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Enhanced Immunogenicity of Foot-and-Mouth Disease Virus-like Particles Using a Water-in-Oil-in-Water Adjuvant by Yujie Zhou, Wenzhu Yin, Zhidong Teng, Yanyan Zhao, Yu Lu, Yingjuan Qian, Bihua Deng

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A cross-study analysis of the effect of a dual-strain probiotic applied via the waterline on the growth performance and gut health of broilers under a mild necrotic enteritis chall... by S.A.S. van der Klein, M. Bernardeau, Q. Wang, K. Gibbs

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Contamination profile of heavy metals in marine fish and shellfish by M.A. Salam, S.C. Paul, S.N.B.M. Noor, S.A. Siddiqua, T.D. Aka, R. Wahab, E.R. Aweng

“…Heavy metals ultimately pass into human body through having aquatic animals like fish, prawn and crab. In this study, accumulation of heavy metals (zinc, copper, iron, cadmium and lead) in various organs of four commonly consumed fish (<em>Euthynnus affinis</em>, <em>Pampus argenteus, </em><em>Descapterus macrosoma, </em>and<em> Leiognathus daura</em>), prawn (<em>Fenneropenaeus indicus) and</em> crab <em>(Portunus pelagicus)</em> of Tok Bali Port, Kelantan, Malaysia were determined<em>. …”
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Identification and characterization of multiple novel viruses in fecal samples of cormorants by Li Ji, Li Ji, Ran Zhao, Yifei Pei, Yijie Sun, Xiaoyi Sun, Likai Ji, Xiaochun Wang, Yuwei Liu, Quan Shen, Shixing Yang, Yan Wang, Wen Zhang

“…IntroductionCormorants, as protected wild animals by the State Forestry Administration of China, have a broad distribution across China. …”
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KULTŪRINIO IR SIMBOLINIO KAPITALO GAMYBA: "DISNEY" FENOMENAS by Gintautas Mažeikis

“…Keywords: Marxist notion of capital, fetishism, personification,  animation, institutionalisation, utopia. …”
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