TNF-α as a Therapeutic Target in Acute Pancreatitis — Lessons from Experimental Models by Giuseppe Malleo, Emanuela Mazzon, Ajith K. Siriwardena, Salvatore Cuzzocrea

“…Different specific and nonspecific inhibitors have been developed with promising results in animal models, but, on the other hand, no clinical trials have been designed so far. …”
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Research progress on Sertoli cell secretion during spermatogenesis by Yao Xiao, Jingyi Zhang, Yanxin Guan, Meijing Wang, Dehong Liu, Shengxi Xiong, Junjun Li, Xujun Yu

“…Moreover, the physiological process of testicular development and spermatogenesis in male animals is intricately tied to the secretory activities of SCs. …”
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Captivity Reduces Diversity and Shifts Composition of the Great Bustard (Otis tarda dybowskii) Microbiome by Zhiyuan Lu, Zhucheng Wang, Hexue Jia, Derong Meng, Dayong Wu

“…Consequently, managing rescued wild animals by increasing dietary diversity and exposure to natural environmental reservoirs may enhance the success rate of reintroduction efforts.…”
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Social Media Advocacy for SDG 5 in the Middle East: Insights from Egypt, Tunisia, and Jordan by Laila El Baradei, Mohamed Kadry, Ghadeer Ahmed

“…“Reproductive health,” “technology,” and “unpaid work”’ were among the lowest-mentioned terms. Videos, animation, and influencers were key factors contributing to the effectiveness of FB posts. …”
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The critical role of anthropology in attaining happiness: An Islamic perspective by Agha-Mohammadi Morteza

“…The article outlines that human perfection progresses through various stages: beginning with stages shared with inanimate objects, advancing to the level of plants, and further progressing through stages associated with animals. Although each stage of perfection is valuable, none can fully satisfy the deep human longing for completeness, fulfillment, and true happiness on its own. …”
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Calcineurin, Synaptic Plasticity, and Memory by Carl Weitlauf, Danny Winder

“…A current experimental strategy is to generate genetically altered mice with mutations in genes thought to be involved in LTP and assess the effects of these mutations both on LTP and animal behavior[1,2]. A difficulty associated with these approaches has been that they are not temporally or spatially refined. …”
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Steppe Eagle Population Structure Genetic Study: is There Hope for the Endangered Species? by Ludmila S. Zinevich, Dmitry M. Schepetov, Valentina G. Tambovceva, Rinur H. Bekmansurov, Genriyetta I. Pulikova, Elvira G. Nikolenko, Igor V. Karyakin

“…The decrease is evidently related to Steppe Eagles’ electrocution at nesting areas and during migration, poisoning by veterinarian drugs feeding on agricultural animal carcasses at wintering grounds, steppe fires and total habitat loss combined with loss of prey like susliks. …”
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The role of short-chain fatty acid in metabolic syndrome and its complications: focusing on immunity and inflammation by Wenqian Yu, Wenqian Yu, Siyuan Sun, Siyuan Sun, Qiang Fu

“…Short-chain fatty acid (SCFA), an organismal energy donor, has recently been demonstrated in an increasing number of studies to be an important molecule in ameliorating immuno-inflammation, an important causative factor of Mets, and to improve lipid distribution, blood glucose, and body weight levels in animal models of Mets. This study reviews recent research advances on SCFA in Mets from an immune-inflammatory perspective, including complications dominated by chronic inflammation, as well as the fact that these findings also contribute to the understanding of the specific mechanisms by which gut flora metabolites contribute to metabolic processes in humans. …”
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Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury by Hitoshi Yui, Uno Imaizumi, Hisashi Beppu, Mitsuhiro Ito, Munetaka Furuya, Hirofumi Arisaka, Kazu-Ichi Yoshida

“…Rabbits received regional ischemia by 30 min of left anterior descending coronary artery occlusion followed by 3 hours of reperfusion under ketamine and xylazine anesthesia. The animals were randomly assigned to the following 4 treatment groups: a control group, a verapamil group, a nicardipine group, and a nitroglycerin group. …”
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Relevansi Nilai-nilai Islam dalam Tradisi Maddoja Bine terhadap Pendidikan Abad 21 by Nurasia, Muzakkir, Syamsuddin

“…The public's belief in a tradition is of course inseparable from the many opinions of the outside community who are of the opinion that the traditions that are still preserved to this day deviate from the teachings of Islam and still contain animism, without clearly knowing what the meaning is and how to implement these traditions as stated in implementation of the Maddoja bine tradition which is the topic of research, the relevance of Islamic values in the Maddoja bine tradition to 21st century education is indeed very important to be studied further and primarily to maintain the existence of the Maddoja bine culture which contains important meanings for the Bugis people in order to ensure sustainability. , as information obtained through interviews using descriptive qualitative research methods, namely 1) the implementation of the Maddoja bine tradition is carried out for two to three days carried out in mutual cooperation, 2) Islamic values in the Maddoja bine tradition consist of aqidah values, sharia values and moral values 3) the relevance of Islamic values in the Maddoja bine tradition to education in the 21st century.…”
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Synergistic enhancement of spinal fusion in preclinical models using low-dose rhBMP-2 and stromal vascular fraction in an injectable hydrogel composite by Hye Yeong Lee, Seong Bae An, Sae Yeon Hwang, Gwang Yong Hwang, Hye-Lan Lee, Hyun Jung Park, Joongkyum Shin, Keung Nyun Kim, Sung Won Wee, Sol Lip Yoon, Yoon Ha

“…The combination of rhBMP-2 and SVF in this injectable formulation yielded superior spinal fusion outcomes, with enhanced mechanical properties and increased bone mass in both small and large animal models. These findings suggest that this strategy offers a promising and safer alternative for spinal fusion, with strong potential for clinical application.…”
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Role of CFT and PCR in diagnosis of Chlamydia psittaci in experimentally infected rabbits by V. V. Evstifeev, F. M. Khusainov, S. I. Yakovlev, R. I. Shangaraev, V. I. Eremets

“…However, when pathological materials from theurogenital tractof theexperimentalanimals weretestedin polymerase chain reaction andin smear microscopy, it was impossibletoconfirm that thereisan etiological linkbetween сhlamydiaandkindlingproblems in experimental animals. At thesametime, molecularandgenetictestsof internalorgans (liver) sampledfromstillborn babyrabbitsrevealedthe сhlamydiagenome, thus, proving сhlamydia involvement into thepathological kindling. …”
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Intermittent Fasting Modulation of the Diabetic Syndrome in Streptozotocin-Injected Rats by Louiza Belkacemi, Ghalem Selselet-Attou, Emeline Hupkens, Evrard Nguidjoe, Karim Louchami, Abdullah Sener, Willy J. Malaisse

“…Over 30 days, groups of 5-6 control or STZ rats were allowed free food access, starved overnight, or exposed to a restricted food supply comparable to that ingested by the intermittently fasting animals. Intermittent fasting improved glucose tolerance, increased plasma insulin, and lowered Homeostatis Model Assessment index. …”
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Estimating energy consumption and GHG emissions in the U.S. food supply chain for net-zero by Kristina Armstrong, Wenquan Dong, Mingzhou Jin, Sachin Nimbalkar, Joe Cresko

“…Among all the stages, on-farm production is the largest energy consumer (31% primary energy) and GHG emissions contributor (70%), largely due to raising animals. Optimizing distribution can reduce the stage’s energy consumption and GHG emissions and increase products’ shelf-life. …”
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Possible relationship between long-term post neutering complications in dogs and caregiver burden in the owners by Idil Bastan

“…These conditions may necessitate ongoing care and treatment, that require special care that the caregiver must provide furthermore burdens the caregiver with daily tasks, which encompasses the emotional, physical, social, and financial impact on pet owners caring for chronically ill animals. This burden can result in burnout, health issues, depression, social isolation, and financial stress. …”
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Stat92E Signaling Following Pre-exposure to Ethanol by Alexandria Wilson, Erica M Periandri, Mackenzie Sievers, Emily Petruccelli

“…Repeated exposure to alcohol alters neuromolecular signaling that influences acute and long-lasting behaviors underlying Alcohol Use Disorder (AUD). Recent animal model research has implicated changes in the conserved JAK/STAT pathway, a signaling pathway classically associated with development and the innate immune system. …”
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Identification of pathogenic bacteria by biosensors in water and wastewater by Sakineh Hargolzadeh, Soheila Kashanian, Maryam Nazari

“…On the other hand, due to the ability of antibiotics to prevent or treat bacterial infections, they have been used as the main method of infection treatment in humans and animals for the past two decades. The irresponsible use of these antibiotics is one of the most important reasons for the emergence of microbial resistance, which has become a global issue. …”
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What Is the Most Cost-Effective Breeding Program for Dairy Heifers—Timed AI, Estrous Detection, or a Combination of Both? by Klibs N. Galvão, Eduardo S. Ribeiro, Jose Eduardo P. Santos

“…Santos, and published by the UF Department of Veterinary Medicine-Large Animal Clinical Sciences, May 2014. VM199/VM199: What Is the Most Cost-Effective Breeding Program for Breeding Heifers—Timed AI, Estrous Detection, or a Combination of Both? …”
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Conceptual Metaphor of “Happiness” in Divan Shams by Abbas Mohammadian, Majid Farhanizadeh

“…Molana has gotten help from the "object", "animal", "food", "plant", "market", and "place" to explain many of happiness features in Divan Shams and he could make this concept concrete and objective. …”
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Is platelet activating factor (PAF) an important mediator in bronchial asthma? by R. H. Gundel, H. O. Heuer, L. G. Letts

“…The development of selective PAF receptor antagonists may provide a novel approach to the treatment of human bronchial asthma. In preclinical animal models of human asthma, PAF receptor antagonists have been found to be efficacious in blocking antigen-induced changes in lung function. …”
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