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10961
Episodic Gregariousness Leads to Level‐Dependent Core Habitats: A Case Study in Eastern Copperheads (Agkistrodon contortrix)
Published 2025-01-01“…ABSTRACT Characterizing the complex relationships between animals and their habitats is essential for effective wildlife conservation and management. …”
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10962
Correlation between Post-Thaw Spermatozoa Quality of the Endangered Javan Banteng with OPN Gene Expression
Published 2023-01-01“…A positive reinforcement approach was used to accustom the male and female animals as we focused on establishing a collection procedure using neither sedation nor anaesthesia. …”
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10963
Field-based evidence for the prevalence of soil antibiotic resistomes under long-term antibiotic-free fertilization
Published 2025-01-01“…This study aimed to quantify the assembly patterns of the antibiotic resistome by in situ probing bacterial community and environmental variations in field soils that have been subjected to long-term exposure to chemical fertilizer and/or manure from animals without antibiotic amendments. Long-term fertilization slightly impacts the diversity of antibiotic resistomes, with 85.5 % of total ARGs and mobile genetic elements (MGEs) being common across all treatment types, while significantly increasing their abundances from 0.68 to a maximum of 0.90 copies/16S rRNA. …”
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10964
Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis
Published 2025-01-01“…The data also suggested that mesalazine could disrupt the integrity of the P. gingivalis cell membrane and inhibit the expression of virulence factors. An animal model of periodontitis in rats was successfully constructed in vivo. …”
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10965
Multi-dimensional evidence from the UK Biobank shows the impact of diet and macronutrient intake on aging
Published 2025-02-01“…Plant-based food consumption correlates with increased telomere length and reduced phenotypic age, while animal-based food intake is linked to adverse aging effects. …”
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10966
Comparative study of PCR test kits for ASFV DNA detection
Published 2021-08-01“…The results of this study demonstrate the need for control of the manufactured diagnostic kits used in state programs for animal disease monitoring.…”
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10967
Identification And Classification of Tattoos In Autopsies; A Retrospective Study
Published 2025-01-01“…Suicides tended to have a higher mean number of shape/geometric/illustrative tattoos, and animal/creature tattoos, compared to natural deaths. …”
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10968
Zooarchaeological investigation of the Hoabinhian exploitation of reptiles and amphibians in Thailand and Cambodia with a focus on the Yellow-headed Tortoise (Indotestudo elongata...
Published 2023-10-01“…This allowed us to study the size structure of the archaeological populations at different sites and to reveal the human exploitation strategies of these animals. We observed a significant taphonomic homogeneity among the studied assemblages, along with similarities in the diversity of hunted reptile and amphibian taxa as well as the size of the exploited tortoises. …”
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10969
A Comparative Evaluation for Biologic Width following Surgical Crown Lengthening Using Gingivectomy and Ostectomy Procedure
Published 2012-01-01“…Histological studies utilizing animal models have shown that postoperative crestal resorption allowed reestablishment of the biologic width. …”
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10970
TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis
Published 2020-01-01“…Insulin sensitivity and inflammation were evaluated in the treated cells or animals. Our results indicated that TLR4/AP-1 siRNA transfection alleviated high-fat diet-induced systemic and hepatic inflammation, obesity, and insulin resistance in mice. …”
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10971
Cardiac-Specific Gene Expression Facilitated by an Enhanced Myosin Light Chain Promoter
Published 2004-04-01“…Discussion: This new vector may be useful to validate therapeutic approaches in animal disease models and offers the perspective for selective expression of therapeutic genes in the diseased heart.…”
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10972
Oncolytic vaccinia virus armed with anti-CD47 nanobody elicit potent antitumor effects on multiple tumor models via enhancing innate and adoptive immunity
Published 2024-12-01“…Additionally, the inclusion of programmed cell death protein-1 inhibiting boosted the anticancer efficacy of OVV-αCD47nb and raised the full response rate in tumor-bearing animals.Conclusion Overall, our findings highlight the therapeutic potential of OVV-αCD47nb for breast and colon cancer, and demonstrate its ability to modulate the immune cell profiles within tumors. …”
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10973
Stem cell-derived exosome treatment for acute spinal cord injury: a systematic review and meta-analysis based on preclinical evidence
Published 2025-01-01“…BackgroundThe study aims were to systematically review and analyze preclinical research on the efficacy of exosomes derived from various mesenchymal stem cell sources (MSC-exos) for the treatment of spinal cord contusion injury (SCI) in small animal models.MethodsWe conducted a systematic search of PubMed, Embase and Google Scholar databases from their inception through February 29, 2024, to identify eligible English-language studies based on predefined inclusion and exclusion criteria. …”
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10974
Mechanism of mTOR/RILP-regulated autophagic flux in increased susceptibility to myocardial ischemia-reperfusion in diabetic mice
Published 2025-01-01“…This was followed by the validation of potential mechanisms of action between impaired autophagic flux and increased susceptibility at the cellular and animal levels, respectively.ResultsAfter I/RI in diabetic myocardium, there was a significant increase in the number of CM1 subgroups and a specific downregulation of 239 autophagy-related genes led by RILP. …”
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10975
Platelet-Rich Plasma Improves the Wound Healing Potential of Mesenchymal Stem Cells through Paracrine and Metabolism Alterations
Published 2019-01-01“…Wound healing in these animals was measured at day 3, day 7, and day 10. …”
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10976
L-Citrulline in Neonates: From Bench to Bed Side
Published 2024-12-01“…Detoxification of endogenously produced superoxide radicals is inadequate in preterm infants due to immature antioxidants that leads to the production of peroxynitrite, a reactive oxygen-free radical that is cytotoxic and causes damage to organelles and cellular membranes, further disrupting the coupling of endothelial NO synthase enzyme and the generation of high levels of reactive nitrogen and oxygen species. Animal studies in lipopolysaccharide-induced models of chorioamnionitis and hyperoxia- and inflammation-induced BPD-PH in rodent lung models revealed that L-CIT supplementation significantly mitigated structural changes in the pulmonary vasculature, preserved alveolar growth, and increased vascular endothelial growth factor gene expression, highlighting the anti-inflammatory and antioxidant effects of L-CIT supplementation. …”
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10977
Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System
Published 2021-01-01“…Studies can be optimized following this workflow, as it is possible to quickly assess more parameters in a small number of animals (injection route, dosage, and fasting conditions). …”
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10978
Methods Used in Urban Search and Rescue in Disasters and Evaluation of Current Approaches
Published 2020-01-01“…Urban search and rescue works are important for finding people and animals trapped under the collapsed structure after the collapse of buildings as a result of earthquakes, terrorist attacks and landslides. …”
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10979
Monitoring of immune activation using biochemical changes in a porcine model of cardiac arrest
Published 2001-01-01“…In animal models, immune activation is often difficult to assess because of the limited availability of specific assays to detect cytokine activities. …”
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10980
Investigating the psychology of eating after exercise — a scoping review
Published 2025-01-01“…Research in children, athletes, or animals was excluded. No country or date restrictions were applied. …”
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