Preclinical Evaluation of Ga-DOTA-Minigastrin for the Detection of Cholecystokinin-2/Gastrin Receptor-Positive Tumors by Maarten Brom, Lieke Joosten, Peter Laverman, Wim J.G. Oyen, Martin Béhé, Martin Gotthardt, Otto C. Boerman

“…Subcutaneous and intraperitoneal tumors were clearly visualized by small-animal PET imaging with 5 MBq 68 Ga-DOTA-MG0. 111 In- and 68 Ga-labeled DOTA-MG0 specifically accumulate in CCK 2 /gastrin receptor-positive AR42J tumors with similar biodistribution apart from the kidneys. …”
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Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics by Xiaomin Xu, Donghua Yu, Yu Wang, Xin Jiang, Fang Lu, Shumin Liu

“…In addition, non-targeted metabolomics techniques were combined to further investigate the mechanism of Res in treating GA.ResultsThe results of network pharmacology showed that Res may exert its therapeutic effects through the NF-κB signaling pathway. Animal experiments demonstrated that in the MSU-induced GA rat model, pathological damage, serum biochemical indicators, and levels of inflammatory factors were significantly increased, and the NF-κB signaling pathway was activated. …”
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Production of probiotic kefir from different plant-based milks by Berra Ceylan, Nilgün Öncül

“…This study has provided alternative plant-based fermented beverages for individuals who do not consume or cannot consume animal-derived products.…”
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The Anti-Cytokine Storm Activity of Quercetin Zinc and Vitamin C Complex by Hayder B. Sahib, Omer Abid Kathum, Rafal Shakeeb Alanee, Rehab A. M Jawad, Ahmed Majeed Al-Shammari

“…Thirty mice were used to investigate the acute toxicity; mice were distributed into six groups: one control group and five treated groups; then several serial dilutions from the complex have been prepared for different concentrations from 5 g/kg to 0.312 g/kg. The animals were observed for 14 days. The LD50 was deduced by the straight-line equation calculated from the dose-response curve. …”
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Growth, Root Formation, and Nutrient Value of Triticale Plants Fertilized with Biosolids by Wendy Mercedes Rauw, Michael Bela Teglas, Sudeep Chandra, Matthew Lewis Forister

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Production of Prodigiosin Using Tannery Fleshing and Evaluating Its Pharmacological Effects by C. Sumathi, D. MohanaPriya, S. Swarnalatha, M. G. Dinesh, G. Sekaran

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Cricket Flour and Pullulan Microparticle Formation via Electro-Blow Spinning as a New Method for the Protection of Antioxidant Compounds from Fruit Extracts by Sabina I. Wilkanowicz, Keara T. Saud

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Comercio y controles de la sal en el estado Mérida entre los años 1882 – 1908 by María Alejandra Rosales Lobo

“…La sal a pesar de no ser un producto fundamental para la economía nacional, fue y sigue siendo un recurso necesario para el consumo humano y animal.…”
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Genetic tracking of Crimean-Congo haemorrhagic orthonairovirus in Hyalomma population infesting cattle in Nigeria. by Oluwafemi Babatunde Daodu, Joseph Ojonugwa Shaibu, Rosemary Ajuma Audu, Daniel Oladimeji Oluwayelu

“…Crimean-Congo haemorrhagic fever virus (CCHFV), a Biosafety level 4 pathogen transmitted by ticks, causes severe haemorrhagic diseases in humans but remains clinically silent in animals. Over the past forty years, Nigeria lacks comprehensive genetic data on CCHFV in livestock and ticks. …”
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In Vitro and In Vivo Wound Healing Activity of Astragalus floccosus Boiss. (Fabaceae) by Fatemeh Akbari, Mohammad Azadbakht, Ali Bagheri, Lale Vahedi

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Detection of Mechanically Recovered Poultry Meat (MRPM) in Traditional Egyptian Luncheon (Emulsion Type Sausage) by Mohamed Mai A., Zahran Dalia A., Kassem Gehan M.A., Emara M.M.T., Mansour N.M.

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Simultaneous determination of 11 kinds of siloxanes in drinking water and source water using solid-phase microextraction combined with gas chromatography-mass spectrometry by Sijie Liu, Jie Ma, Su Jiang

“…It has been reported that methylsiloxane has toxic effects on the nervous, immune and reproductive systems of aquatic animals, and is carcinogenic and mutagenic. Therefore, in order to protect human health, it is urgent to establish a method for the determination of siloxane content in drinking water and source water.MethodsHerein, this paper proposes a precise, fast, and selective method using solid-phase microextraction combined with gas chromatography-mass spectrometry (GC-MS/MS) method for the simultaneous detection of 11 kinds of siloxanes in drinking water and source water. …”
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Heterozygous mutation in BRCA2 induces accelerated age-dependent decline in sperm quality with male subfertility in rats by Yashiro Motooka, Hideaki Tanaka, Yuki Maeda, Misako Katabuchi, Tomoji Mashimo, Shinya Toyokuni

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Immunomodulatory Potential of Piperine in Rats by Alireza Ghavami, Seyyed Meysam Abtahi Froushani, Aliasghar tehrani

“…In a separate set of experiments, the effects of piperine gavage on T helper lymphocyte responses in vivo and ex vivo and their subsets were performed in animals challenged with ovalbumin (OVA). Results: Oral administration of piperine for one month reduced the adhesion of neutrophils (p=0.04). …”
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Vermicomposting of different organic materials using the epigeic earthworm Eisenia foetida by Yvonne Indrani Ramnarain, Abdullah Adil Ansari, Lydia Ori

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Genome-wide transcriptomics revealed carbon source-mediated gamma-aminobutyric acid (GABA) production in a probiotic, Lactiplantibacillus pentosus 9D3 by Nachon Raethong, Pitakthai Chamtim, Roypim Thananusak, Kanyawee Whanmek, Chalat Santivarangkna

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Optimizing a modified cetyltrimethylammonium bromide protocol for fungal DNA extraction: Insights from multilocus gene amplification by Dar Gulam Jeelani, Nazir Ruqeya, Wani Shakil A., Farooq Saleem, Aziz Tariq, Albekairi Thamer H.

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Berberrubine protects against cisplatin-induced ototoxicity by promoting folate biosynthesis by Zhuang Miao, Danyang Chang, Xiaodong Du, Changling Sun

“…The mechanism of action of BB was explored using RNA-Seq and qRT-PCR analysis.ResultsBB significantly improved cell survival rates under cisplatin treatment, reduced levels of apoptotic markers (TUNEL, Cleaved Caspase-3, Annexin V-PI), decreased ROS and MitoSOX levels, and improved JC-1 signals in both HEI-OC1 cells and cochlear hair cells in cochlear explants culture. Animal studies demonstrated that treatment with BB enhanced the survival of cochlear hair cells, reduced hearing impairment caused by cisplatin in mice. …”
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The Nod2 Agonist Muramyl Dipeptide Cooperates with the TLR4 Agonist Lipopolysaccharide to Enhance IgG2b Production in Mouse B Cells by Sang-Hoon Lee, Jong-Hwan Park, Seok-Rae Park

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Chemical Composition of Covered and Naked Spring Barley Varieties and Their Potential for Food Production by Šterna Vita, Zute Sanita, Jansone Inga, Kantane Inara

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