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9901
Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasi...
Published 2023-11-01“…All these behavioral changes were observed mostly when animals were tested in water scented by potential predators (here brown trout), suggesting condition-dependent manipulation. …”
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9902
Caspase-11 Modulates Inflammation and Attenuates Toxoplasma gondii Pathogenesis
Published 2016-01-01“…To better elucidate the function of this noncanonical inflammasome in toxoplasmosis, we utilized Asc−/− and Casp11−/− mice and infected these animals with T. gondii. Our data indicates that caspase-11 modulates the innate immune response to T. gondii through a mechanism which is distinct from that currently described for the canonical inflammasome. …”
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9903
Adrenalectomy improves MSG-induced obesity in rats by increasing UCP-1 levels in interscapular brown adipose tissue
Published 2025-01-01“…Although it has an adverse effect on the glucose tolerance of CTL-ADX animals, the typical features of metabolic syndrome in adult MSG rats were mitigated by ADX. …”
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9904
Exploring <i>RNF213</i> in Ischemic Stroke and Moyamoya Disease: From Cellular Models to Clinical Insights
Published 2024-12-01“…This review synthesizes findings from genetic studies, as well as cellular and animal models, to provide a holistic understanding of <i>RNF213</i>’s involvement in cerebrovascular diseases. …”
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9905
Simultaneously delivery of functional gallium ions and hydrogen sulfide to endow potentiated treatment efficacy in chemo- and PARPi-resistant ovarian cancer
Published 2025-02-01“…More importantly, the therapeutic efficacy of Ga2S3-BSA NMs and their ability to enhance the sensitivity to carboplatin and fluzoparib with negligible toxicity were further confirmed in a platinum-resistant OC animal model. Altogether, our results demonstrated a potentially safe and practical strategy by using Ga2S3-BSA NMs to combat drug resistance in platinum-resistant OC. …”
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9906
NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats
Published 2016-01-01“…PCBs, widespread endocrine disruptors, cause the disturbance of thyroid hormone (TH) homeostasis in humans and animals. However, the exact mechanism of thyroid dysfunction caused by PCBs is still unknown. …”
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9907
Diversity and Conservation of Carnivores in Saudi Arabia
Published 2024-12-01“…Major threats affecting carnivores include killing and animal trade. The status of the critically endangered species, <i>Panthera pardus nimr</i>, was discussed. …”
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9908
Determining of β-lactamase activity and resistanee against some antibiotics of staphyloeoeeus strains isolated from bovine mastilis
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9909
A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis
Published 2025-01-01“…Most of these are involved in the transduction of key signals during embryonic development and in the regulation of cholesterol homeostasis. In oviparous animals, the VLDL receptor is also known as VTGR since it facilitates the uptake of vitellogenin in ovary. …”
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9910
Blood transcriptome resources of chinstrap () and gentoo () penguins from the South Shetland Islands, Antarctica
Published 2019-03-01“…Because blood and tissues of penguins have been used to monitor pollution in Antarctica, immune parameters in blood could be important indicators for understanding the health status of penguins and other Antarctic animals. In the blood transcriptomes, KEGG analyses detected many essential genes involved in the major innate immunity pathways, which are key metabolic pathways for maintaining homeostasis against exogenous infections or toxins. …”
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9911
Selected Parameters of Nutritional and Pro-Health Value in the Common Carp (Cyprinus carpio L.) Muscle Tissue
Published 2018-01-01“…In all analysed cases, the values of these indices were very favourable and several times lower than for other animal fats.…”
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9912
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment
Published 2025-01-01“…However, the underlying cellular mechanisms involved are largely unknown, and advancements in the field have been limited by the existing tools and animal models. Zebrafish are an excellent model for studying neurodevelopmental mechanisms. …”
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9913
Genotoxicity Assessment and Protective Effect of Anogeissus leiocarpus Roots against Cyclophosphamide-Induced DNA Damage In Vivo
Published 2021-01-01“…The administration of A. leiocarpus did neither increase the ratio of the polychromatic erythrocyte (PCE) nor the frequency of micronucleated PCE (MNPCE) significantly in the bone marrow cells of the mice, compared to the vehicle control animals. However, a significant increase in the incidence of MNPCE in the bone marrow cell of the cyclophosphamide-treated mice was found. …”
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9914
Unveiling the role of SYNGR4 in breast cancer development: a novel target for immunotherapy
Published 2025-01-01“…The effect of SYNGR4 on immune infiltration of breast cancer was analyzed using GSVA, and the effects of SYNGR4 on breast cancer proliferation, migration, and tumor-associated macrophage polarization in cancer foci were verified by cellular and animal experiments, respectively.ResultsSYNGR4 is highly expressed in a variety of malignant tumors, including breast cancer, and affects the prognosis of breast cancer patients. …”
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9915
Development of Asthma Mouse Model By Dermal Sensitization
Published 2024-12-01“…Extensive research has been done on the prevalence and triggering factors of asthma, however, no experimental research using animal models has been done. Thus, this study aims to develop asthma phenotype in mice with TDI sensitization. …”
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9916
The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin
Published 2016-01-01“…Clostridium perfringens (C. perfringens) beta2 toxin (CPB2) is an important virulent factor of necrotic enteritis in both animals and humans. However, studies of its pathogenic roles and functional mechanisms have been hampered due to the difficulty of purification and lack of specific antibodies against this toxin. …”
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9917
Analysis of somatic piRNAs in the malaria mosquito Anopheles coluzzii reveals atypical classes of genic small RNAs
Published 2025-02-01“…Piwi-interacting small RNAs (piRNA) play a key role in controlling the activity of transposable elements (TEs) in the animal germline. In diverse arthropod species, including the pathogen vectors mosquitoes, the piRNA pathway is also active in nongonadal somatic tissues, where its targets and functions are less clear. …”
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9918
Phenotypic Plasticity in Gut Length in the Planktivorous Filter-Feeding Silver Carp (Hypophthalmichthys molitrix)
Published 2008-01-01“…Phenotypic plasticity widely exists in the external morphology of animals as well as the internal traits of organs. …”
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9919
Comparative Biotypic and Phylogenetic Profiles of Escherichia coli Isolated from Resident Stool and Lagoon in Fresco (Côte d’Ivoire)
Published 2019-01-01“…The diversity of E. coli biotypes observed in this study revealed animal and human origins of contaminations. A close relationship was found between water and human strains, and the presence of commensal and extraintestinal pathogenic E. coli in all samples could represent a potential reservoir of extraintestinal infections for resident populations.…”
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9920
Preventive effects of Bifidobacterium lactis Probio-M8 on ovalbumin-induced food allergy in mice
Published 2024-07-01“…Certain probiotics have been found to enhance food allergy by regulating immune-microbe interactions in animal models and patients. However, the effects of Bifidobacterium lactis Probio-M8 on food allergy have not been thoroughly investigated. …”
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