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9441
Effects of Mating and Social Exposure on Cell Proliferation in the Adult Male Prairie Vole (Microtus ochrogaster)
Published 2020-01-01“…Males were assigned to one of the four groups: (1) control: males were placed alone in a clean cage; (2) social exposure to a female (SE m/f): males that could see, hear, and smell a sexually receptive female but where physical contact was not possible, because the animals were separated by an acrylic screen with small holes; (3) social exposure to a male (SE m/m): same as group 2 but males were exposed to another male without physical contact; and (4) social cohabitation with mating (SCM): males that mated freely with a receptive female for 6 h. …”
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9442
Polymorphism of lipid exchange genes in some populations of South and East Siberia
Published 2020-01-01“…Indigenous peoples of Siberia have a specific genetically determined type of metabolism supporting such lipid blood parameters that favor increased consumption (in comparison with Caucasians) of animal products. At the same time, indigenous Siberian ethnic groups are less susceptible to metabolic diseases. …”
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9443
Screening and Characterization of High Protein Yeast with Excellent Stress Tolerance
Published 2025-01-01“…Protein feed resources in China are scarce, which hinders the developement of feed industry and animal husbandry. Yeast protein is rich in nutrients and has significant development potential. …”
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9444
Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways
Published 2025-01-01“…Results The expressions of NRG1 in MAFLD cell and animal models were significantly lower than that in the control group. …”
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9445
Blue applicability grade index assessment and response surface modelling to synchronous determination of metformin hydrochloride, vildagliptin and dapagliflozin propanediol monohyd...
Published 2025-02-01“…But these chromatographic analyses promoted usage of toxic organic solvents which are harmful to the environment and aquatic animal lives. In addition, no chromatographic method was found in the literature for simultaneous estimation of these anti-diabetic drugs using green solvents. …”
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9446
Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota
Published 2025-01-01“…The different groups of animals were compared in terms of neurological score, cerebral infarct volume, brain edema, brain and gut histopathology to assess stroke severity. …”
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9447
An analysis of observed and predicted extreme heat and precipitation trends across four pulse producing regions in North America: North Dakota, Montana, Saskatchewan, and Northeast...
Published 2025-01-01“…The consumption of plant-based proteins in lieu of animal proteins is the most important dietary shift that would be needed to keep the world under 2 °C of warming, and this shift would require a dramatic increase in the percentage of cropland devoted to nuts and pulses (Peters et al 2016 Elementa 4 000116). …”
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9448
GluN2D-containing NMDA receptors in parvalbumin neurons in the nucleus accumbens regulate nocifensive responses in neuropathic pain
Published 2025-02-01“…Using conditional KO strategy, we addressed the region- and cell-type involved in GluN2D-mediated changes in CINP. Animals with conditional deletion of GluN2D receptors from parvalbumin interneurons (PVIs) or local ablation of GluN2D from nucleus accumbens (NAc) displayed reduced mechanical hypersensitivity in CINP, underscoring the pivotal role of accumbal GluN2D in PVIs in neuropathic pain. …”
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9449
Vanadyl Sulfate Effects on Systemic Profiles of Metabolic Syndrome in Old Rats with Fructose-Induced Obesity
Published 2018-01-01“…Vanadyl sulfate (VS) has been investigated as a hypoglycemic compound in animal and human studies showing effective insulin-mimetic properties. …”
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9450
Hepatoprotection and Phytochemistry of the Vietnamese Herbs Cleome chelidonii and Cleome viscosa Stems
Published 2021-01-01“…The results show that CCSM and CVSM significantly expressed in vitro hepaprotective activity on HepG2. Therefore, the animals were daily treated with these extracts at the doses of 15, 30, and 45 mg/kg body weight for 5 days, and CCl4 was injected (2 ml/kg body weight, i.p.) on the 2nd and 3rd days. …”
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9451
Effect of Massage on the TLR4 Signalling Pathway in Rats with Neuropathic Pain
Published 2020-01-01“…The control group consisted of intact animals. The rats in the massage group underwent massage using a massage simulation machine once a day for 14 d in succession; the hind limbs of the rats in the sham massage group were gently touched with a cloth bag once a day for 14 continuous days. …”
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9452
FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms
Published 2025-03-01“…Whereas FNDC5 overexpression in murine heart was cardioprotective, introduction of FNDC5-targeted shRNA into the myocardium was sufficient to trigger Bax up-regulation, ATR/Chk1 activation, oxidative stress, cardiac fibrosis, loss of ventricular function, and compromised animal survival. The detrimental impact of FNDC5 depletion on heart function could be mitigated via treatment with a Chk1 inhibitor identifying Chk1 hyperactivity as a causative factor in cardiac disease. …”
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9453
Mutations in the <i>A34R</i> gene increase the immunogenicity of vaccinia virus
Published 2021-04-01“…Therefore, the development of new safe vaccines against orthopoxviral infections of humans and animals is an important problem. VACV attenuation by modern approaches carried out by targeted inactivation of certain virus genes and usually leads to a decrease in the effectiveness of VACV in vivo propagation. …”
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9454
The effects of Lepidium meyenii on MSG-induced subfertility in male Wistar rats: Targeting oxidative stress, pro-inflammatory cytokines, steroidogenic enzymes, and reproductive hor...
Published 2025-02-01“…Methods: Eighteen male Wistar rats were randomly divided into three groups. Animals were orally (oral gavage) administered MSG (900 mg/kg/day for 45days), MSG and Maca (900 mg/kg/day of MSG and 500 mg/kg/day of black Lepidium meyenii root extract), or water only (control group), for a total period of 80 days. …”
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9455
Evaluation of the possibility of Spirulina Spirulina platensis culture in the deep aquifer well, Seistan, Southeastern Iran
Published 2023-09-01“…In addition to human consumption, Spirulina is used in aquaculture for feeding the larval stages of crustaceans and some other types of aquatic animals, to prepare livestock and poultry feed, and for cosmetic and industrial purposes. …”
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9456
Transcriptome analysis reveals potential regulatory mechanism of genes and pathways following Aeromonas veronii infection and hypoxic stress in Chinese mitten crab, Eriocheir sinen...
Published 2025-03-01“…These findings contribute to understanding the mechanisms of stress responses in aquatic animals, potentially aiding in the development of strategies to enhance health and productivity in aquaculture.…”
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9457
Transcriptomic responses of sponge holobionts to in situ, seasonal anoxia and hypoxia
Published 2024-04-01“…Deoxygenation can be fatal for many marine animals; however, some sponge species are tolerant of hypoxia and anoxia. …”
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9458
Blast‐Overpressure Induced Modulation of PARP‐SIRT‐NRF2 Axis in Stress Signaling of Astrocytes and Microglia
Published 2025-01-01“…Poly adenosine diphosphate (ADP) ribose polymerase‐1 (PARP1) is implicated in the parthanatos and secondary neuroinflammation. Animal studies indicate the over‐activation of PARP1 as a significant downstream event underlying the neurological sequelae of several traumatic and neurodegenerative disorders, irrespective of the mode of cell death. …”
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9459
Can Thinning Foster Forest Genetic Adaptation to Drought? A Demo‐Genetic Modelling Approach With Disturbance Regimes
Published 2024-12-01“…Considering plausible genetic variation and contrasting drought regimes, the predicted evolutionary rates for both traits aligned with documented rates in wild plant and animal populations. Thinning considerably reduced natural selective pressures caused by competition and drought compared to unthinned stands. …”
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9460
Association between prenatal exposure to phthalate esters and blood pressure in children aged 3–7 years: A prospective cohort study
Published 2025-01-01“…Background: An increasing number of animal studies have indicated that exposure to phthalate esters (PAEs) may cause high blood pressure. …”
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