Induced Pluripotent Stem Cells Reduce Progression of Experimental Chronic Kidney Disease but Develop Wilms’ Tumors by Heloisa Cristina Caldas, Fernando Henrique Lojudice, Cinthia Dias, Ida Maria Maximina Fernandes-Charpiot, Maria Alice Sperto Ferreira Baptista, Rosa Sayoko Kawasaki-Oyama, Mari Cleide Sogayar, Christina Maeda Takiya, Mario Abbud-Filho

“…Untreated 5/6 nephrectomized rats were compared with CKD animals receiving BMSCs or iPSs. Renal function, histology, immunohistochemistry, and gene expression were studied. …”
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Evaluation of encountered claw lesions in dairy farm (brown swiss) in konya province by Hanifi Erol, Muharrem Erol, Fahrettin Alkan

“…The detected lesion of 61% were horn lesions, and 39% were corium lesions. The eleven animals with severe claw lesions were referred for slaughtering and 69 animals were treated.…”
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Application of a ImageJ-Based Method to Measure Blood Flow in Adult Zebrafish and Its Applications for Toxicological and Pharmacological Assessments by Ferry Saputra, Tzu-Ming Tseng, Franelyne P. Casuga, Yu-Heng Lai, Chih-Hsin Hung, Chung-Der Hsiao

“…Blood flow is an important physiological endpoint to measure cardiovascular performance in animals. Because of their innate transparent bodies, zebrafish is an excellent animal model for assessing in vivo cardiovascular performance. …”
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The effectiveness of inactive arcanobacterium pyogenes vaccines in mice by Hasan Hüseyin Hadimli*, Zafer Sayın, Yasemin Pınarkara, Aslı Sakmanoğlu, M. Seyyide Temimhan, Osman Erganiş

“…<p> <b>Results:</b> Levels of antibodies in sera of vaccinated animals were significantly higher than the controls. …”
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Antilipoxygenase and Anti-Inflammatory Activities of Streblus asper Leaf Extract on Xylene-Induced Ear Edema in Mice by Kanathip Singsai, Pimchanok Charoongchit, Waritsara Chaikaew, Nirut Boonma, Pitsinee Fhanjaksai, Karitta Chaisatan

“…An in vitro antilipoxygenase study was performed using a lipoxygenase assay, and the oxidation of linoleic acid into 13-hydroperoxy linoleic acid (HPODE) was detected with a UV spectrophotometer at a wavelength of 234 nm. In the animal study, twenty-five male ICR mice were induced as ear edema by topical xylene, and the ear thickness of the mice was measured. …”
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Cardiometabolic Changes in Different Gonadal Female States Caused by Mild Hyperuricemia and Exposure to a High-Fructose Diet by J. Soutelo, Y. A. Samaniego, M. C. Fornari, C. Reyes Toso, O. J. Ponzo

“…Fifty-six (56) adult female Wistar rats were used in the present work. Animals were divided into two groups: normogonadic (NGN) and hypogonadic (HGN). …”
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Pueraria tuberosa DC Extract Improves Androgenesis and Sexual Behavior via FSH LH Cascade by Nagendra Singh Chauhan, Vikas Sharma, Mayank Thakur, Alexandra Christine Helena Frankland Sawaya, V. K. Dixit

“…A dose-dependent increase in sexual behaviors was evidenced in the animals of extract treated groups. Increase in testis weight was recorded in PT. …”
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Quantifying conjugation rates in clinical and environmental matrices: a systematic review to inform risk assessment by Hunter Quon, Hunter Quon, Lucia Ramirez, Blakeley Bagwell, Jennifer Moralez, Richard J. Sheppard, Allison J. Lopatkin, Allison J. Lopatkin, Kerry A. Hamilton, Kerry A. Hamilton

“…The transfer of antimicrobial resistance genes (ARG) between bacteria and the movement of antibiotic resistant bacteria (ARB) between human, environmental, and animal reservoirs allows AMR to spread and drive its persistence. …”
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Specific features of African swine fever control activities in China by M. D. Lozovoy, S. V. Shcherbinin, A. K. Karaulov

“…The country with the largest swine population in the world achieved rather moderate spread rates if compared to Europe.In addition, the virus strains, which circulated in the Chinese territory, were genetically diverse and different in virulence, leading to a wide range of clinical signs manifested by diseased animals. Such aspects were supposed to complicate the eradication measures, but instead, they proved their effectiveness. …”
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Hepatic transcript profiling in beef cattle: Effects of rumen-protected niacin supplementation. by Gastón F Alfaro, Valentino Palombo, Mariasilvia D'Andrea, Wenqi Cao, Yue Zhang, Jonathan Beever, Russell B Muntifering, Wilmer J Pacheco, Soren P Rodning, Xu Wang, Sonia J Moisá

“…Therefore, results from our study showed that the liver transcriptional machinery switched several metabolic pathways to a condition that could potentially benefit the health status of animals supplemented with rumen-protected niacin. …”
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Carvacrol attenuates N-nitrosodiethylamine induced liver injury in experimental Wistar rats by Balan Rajan, Rajendran Ravikumar, Thandavamoorthy Premkumar, Thiruvengadam Devaki

“…The hoisted activities of Phase I enzymes and inferior activities of Phase II enzymes were observed in DEN-administered animals, whereas Carvacrol treated animals showed improved near normal activity. …”
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Influence of Angiotensin II Subtype 2 Receptor (AT2R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subt... by Emma S. Jones, M. Jane Black, Robert E. Widdop

“…Perivascular fibrosis was significantly reduced by candesartan cilexetil in aged animals only, and this effect was reversed by concomitant PD123319 administration. …”
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Feasibility and Safety of Continuous and Chronic Bilateral Deep Brain Stimulation of the Medial Forebrain Bundle in the Naïve Sprague-Dawley Rat by Luciano L. Furlanetti, Máté D. Döbrössy, Iñigo A. Aranda, Volker A. Coenen

“…MFB-DBS resulted in mild and temporary weight loss in the animals, which was regained even with continuing stimulation. …”
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Anti-PD-1 exacerbates bleomycin-induced lung injury in mice via Caspase-3/GSDME-mediated pyroptosis by Fei Wang, Haiyi Deng, Maolin Zhou, Yilin Yang, Jiankui Zhou, Yansheng Wang, Xiaohong Xie, Xinqing Lin, Ming Liu, Gengyun Sun, Chengzhi Zhou

“…However, the lack of mouse animal models of ICI-related lung injury (ICI-LI) has limited the in-depth exploration of its pathogenesis. …”
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Combination of Single-Photon Emission Computed Tomography and Magnetic Resonance Imaging to Track In-Oxine–Labeled Human Mesenchymal Stem Cells in Neuroblastoma-Bearing Mice by Lorena Cussó, Isabel Mirones, Santiago Peña-Zalbidea, Verónica García-Vázquez, Javier García-Castro, Manuel Desco

“…Initially, the images showed similar activity in the abdomen in both controls and hMSC-injected animals. In general, abdominal activity decreases at 48 hours. hMSC-injected animals showed increased uptake in the tumor area at 48 hours, whereas the control group showed a low level of activity at 24 hours, which decreased at 48 hours. …”
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Evolution under intensive industrial breeding: skull size and shape comparison between historic and modern pig lineages by A. Haruda, A. Evin, F. Steinheimer, R. Schafberg

“…Domestication and subsequent human-induced selection has enhanced profound changes in animal morphology. On modern domestic pigs, those transformations encompass not only overall increases in body size but also modifications in skull morphology. …”
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USE OF REAL-TIME qRT-PCR FOR FMD VIRUS DETECTION IN CATTLE MILK by A. M. Timina, S. N. Fomina, Т. К. Mayorova

“…FMDV can be shed with milk of infected animals and infect susceptible animals. The possibility of using real-time qRT-PCR for FMD virus detection in cattle milk was assessed. …”
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A Proof-of-Concept for Safety Evaluation of Inhalation Exposure to Known Respiratory Irritants Using In Vitro and In Silico Methods by Nikaeta Sadekar, Holger Peter Behrsing, Tanja Hansen, Vivek Patel, Hazel Paulo, Alex Rae, Detlef Ritter, Katharina Schwarz, Anne Marie Api

“…There is increased interest in developing non-animal test systems for inhalation exposure safety assessments. …”
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More than just a number: the gut microbiota and brain function across the extremes of life by Nathan D. Nuzum, Clara Deady, Sarah Kittel-Schneider, John F. Cryan, Siobhain M. O'Mahony, Gerard Clarke

“…Neurodevelopmental research has also seen a boon in microbiome-related clinical research including in autism, Attention-deficit/hyperactivity disorder, and schizophrenia, which is confirming prior animal model work regarding the key time-windows in the gut microbiome important for infant cognition. …”
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Electron Microscopic Radioautographic Study on Mitochondrial DNA Synthesis in Adrenal Cortical Cells of Developing and Aging Mice by Tetsuji Nagata

“…On EM radioautograms obtained from each animal, the number of mitochondria and the mitochondrial labeling index labeled with 3H-thymidine showing DNA synthesis in each adrenal cortical cell, in three zones, were counted and the results in respective developing groups were compared. …”
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