ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice by Ninon Foussard, Célia Bourguignon, Virginie Grouthier, Caroline Caradu, Candice Chapouly, Alain-Pierre Gadeau, Thierry Couffinhal, Marie-Ange Renault

“…Consistent with this kinetics, we found that angiogenesis and myogenesis which typically occur between day five and day 14 post-surgery are not impaired in mice in which diabetes was induced by a high fat diet and streptozotocin injections (HFD STZ mice). …”
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Reduction reactions dominate the interactions between Mg alloys and cells: Understanding the mechanisms by Jua Kim, Jeremy L. Gilbert, William W. Lv, Ping Du, Haobo Pan

“…Magnesium (Mg) alloys are popular biodegradable metals studied for orthopedic and cardiovascular applications, mainly because Mg ions are essential trace elements known to promote angiogenesis and osteogenesis. However, Mg corrosion consists of oxidation and reduction reactions that produce by-products, such as hydrogen gas, reactive oxygen species, and hydroxides. …”
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Oocyte transcriptomes and follicular fluid proteomics of ovine atretic follicles reveal the underlying mechanisms of oocyte degeneration by Yukun Song, Erhan Hai, Nan Zhang, Yu Zhang, Junlan Wang, Xitong Han, Jiaxin Zhang

“…Additionally, we uncovered 333 differentially expressed proteins that may coordinate follicular atresia and revealed key pathways, such as negative regulation of angiogenesis, metabolic pathways, and transcription and mRNA splicing, that lead to oocyte degeneration. …”
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A spatial model of tumor-host interaction: Application of chemotherapy by Peter Hinow, Philip Gerlee, Lisa J. McCawley, Vito Quaranta, Madalina Ciobanu, Shizhen Wang, Jason M. Graham, Bruce P. Ayati, Jonathan Claridge, Kristin R. Swanson, Mary Loveless, Alexander R. A. Anderson

“…The initially avascular tumor reaches a diffusion limited size of the order of millimeters and initiates angiogenesis through the release of vascular endothelial growth factor (VEGF) secreted by hypoxic cells in the core of the tumor. …”
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Nephronectin Is Required for Vascularization in Zebrafish and Sufficient to Promote Mammalian Vessel‐Like Structures in Hydrogels for Tissue Engineering by Chinmoy Patra, Amey Rayrikar, Ganesh Wagh, Florian Kleefeldt, Kaveh Roshanbinfar, Florian Cop, Iva Nikolic, Mirko H. H. Schmidt, Amparo Acker‐Palmer, Süleyman Ergün, Felix B. Engel

“…Nephronectin a morphants and mutants exhibit diminished axial vein sprouting and posterior intersegmental vessel growth. Notably, the angiogenesis‐associated integrins itgav and itgb3.1 are coexpressed with nephronectin a in the region of the caudal vein plexus and posterior somites; nephronectin binds to integrin alpha‐V/integrin beta‐3.1 (ITGAV/ITGB3.1), and itgav morphants phenocopy nephronectin a mutants. …”
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Behavioral Improvement and Regulation of Molecules Related to Neuroplasticity in Ischemic Rat Spinal Cord Treated with PEDF by Chary Marquez Batista, Leonardo Luis Torres Bianqui, Bruno Bonganha Zanon, Mauricio Menezes Aben Athar Ivo, Gabriela Pintar de Oliveira, Jessica Ruivo Maximino, Gerson Chadi

“…Molecules related to neuroplasticity (MAP-2), those that are able to modulate such event, for instance, neurotrophic factors (NT-3, GDNF, BDNF, and FGF-2), chondroitin sulfate proteoglycans (CSPG), and those associated with angiogenesis and antiapoptosis (laminin and Bcl-2) and Eph (receptor)/ephrin system were evaluated at cellular or molecular levels. …”
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A scoping review examining the relationship between green tea and skin cancers by Ram Lakhan, Louisa Summers, Olugbemiga Ekundayo, Jedidiah Radosevich, Sierra Turner, Sangyal Dorjee, Vinayak K. Nahar, Manoj Sharma

“…Particularly, EGCG has been found as a contributing factor to inhibit cell invasion, angiogenesis, and metastasis in skin cancer. Discussion: Use of green tea and its extracts may offer promising implications for use in humans about prevention and retarding the progress of skin cancers but at present, the data are very limited. …”

Highly effective treatment of bacterial infection-accompanied wounds by fat extract-embedded phototherapeutic hydrogel by Haonan Wang, Yingnan Xiao, Deli Zhuge, Genghe Shi, Chengping Liu, Hui Liang, Jing Wu, Yunxuan Huang, Yilin Xie, Chunnan Hu, Jiafeng Xie, Xinyi Wang, Yao Yao, Fang Wang, Xufei Zhang, Chengke Huang, Yingzheng Zhao, Weiyang Meng, Yijie Chen, Mengchun Chen

“…Concurrently, this superstructure accelerates wound healing by enhancing angiogenesis and collagen deposition while reducing inflammation. …”
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New acorane-sesequiterpenes and anti-retinoblastoma constituents from the marine algicolous fungus Trichoderma harzianum NTU2180 guided by molecular networking strategy by Andrea Gu, Fan-Li Lin, Chung-Kuang Lu, Tz-Wei Yeh, Yih-Fung Chen, Ho-Cheng Wu, Tzong-Huei Lee

“…It is worth noting that compound 11 was identified as a dual inhibitor targeting both angiogenesis and proliferation of retinoblastomas. Altogether, the results revealed the novel potential of T. harzianum for developing natural therapeutics against retinoblastomas.…”
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Expression of angiotensin converting enzyme 2 in patients with oral squamous cell carcinoma by Shivani Sivasakthivel, Pratibha Ramani, Selvaraj Jayaraman

“…As a component of the renin-angiotensin system (RAS), Angiotensin-Converting Enzyme 2 (ACE2) has been reported to restrain the progression of hepatocellular carcinoma (HCC) and non-small cell lung cancer (NSCLC) by inhibiting angiogenesis, nevertheless the role of ACE 2 in Oral Squamous Cell Carcinoma progression remains unexplored. …”
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β-Caryophyllene and Statins in Bone Fracture Healing – A Narrative Review by Marom H, Khan MA, Darvish N, Tornetta III P, Khoury A, Weil YA, Skelley NW, Allison DC, Meiron S, Ehrmann Barr T

“…It highlights the complementary mechanisms of these agents: BCP’s anti-inflammatory and osteogenic properties and statins’ ability to inhibit osteoclast activity and promote angiogenesis. Combining BCP and statins could offer a multifaceted approach to enhance fracture healing, reduce complications, and improve patient outcomes. …”
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Anti-Inflammatory and Anti-Migratory Effects of Morin on Non-Small-Cell Lung Cancer Metastasis via Inhibition of NLRP3/MAPK Signaling Pathway by Punnida Arjsri, Kamonwan Srisawad, Sonthaya Umsumarng, Pilaiporn Thippraphan, Songyot Anuchapreeda, Pornngarm Dejkriengkraikul

“…High rates of metastasis contribute significantly to the poor prognosis of NSCLC, in which inflammation plays an important role by enhancing tumor growth, angiogenesis, and metastasis. Targeting inflammatory pathways within cancer cells may thus represent a promising strategy for inhibiting NSCLC metastasis. …”
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Effects of Negative Pressure Wound Therapy on Levels of Angiopoetin-2 and Other Selected Circulating Signaling Molecules in Patients with Diabetic Foot Ulcer by Jerzy Hohendorff, Anna Drozdz, Sebastian Borys, Agnieszka H. Ludwig-Slomczynska, Beata Kiec-Wilk, Ewa L. Stepien, Maciej T. Malecki

“…We assessed NPWT’s effect on the plasma levels of angiopoietin-2 (Ang2), a key regulator of angiogenesis, and its microvesicular receptors (Tie2) as well as the microvesicles (MVs) themselves in DFU patients. …”
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Expression and Function of Ephrin-B1 and Its Cognate Receptor EphB2 in Human Abdominal Aortic Aneurysm by Aiji Sakamoto, Masaaki Kawashiri, Hatsue Ishibashi-Ueda, Yuka Sugamoto, Tsuyoshi Yoshimuta, Takeo Higashikata, Hitoshi Ogino, Hayato Tada, Tetsuo Konno, Kenshi Hayashi, Masakazu Yamagishi

“…We examined the expression of ephrin-B1 and its cognate receptor EphB2, key regulators of angiogenesis and embryogenesis, in human abdominal aortic aneurysm (AAA) and analyzed their functional roles in cell migration. …”
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Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study by Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi

“…Early research primarily focused on angiogenesis, dendritic cells, and expression markers, while recent trends have shifted towards phase III trials, adverse reactions, and checkpoint inhibitors, underscoring the field’s dynamic progression.ConclusionFuture research will expand on the pathological mechanisms underlying these therapies and novel interventions and combination strategies. …”
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Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist by Jarosz-Biej Magdalena, Czapla Justyna, Ciepła Joanna, Smolarczyk Ryszard, Drzyzga Alina, Sprus-Lipka Dorota, Pilny Ewelina, Matuszczak Sybilla, Cichoń Tomasz

“…TLR7 agonist inhibited angiogenesis in treated mice. Functional vascular normalization by IMQ increases the effectiveness of low dose of doxorubicin. …”
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To Explore the Pathogenesis of Vascular Lesion of Type 2 Diabetes Mellitus Based on the PI3K/Akt Signaling Pathway by Jia-Rong Gao, Xiu-Juan Qin, Zhao-Hui Fang, Li-Shan, Li-Ping Han, Hui-Jiang, Ming-Fei Guo, Nan-Nan Jiang

“…Protein expression of PTEN in the high-sugar stimulus group was lower than the control group. Conclusions. Angiogenesis is an important pathogenesis of T2DM vascular disease, and PTEN plays a negative regulatory role in the development of new blood vessels and can inhibit the PI3K/Akt signaling pathway.…”
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LncRNA TUG1 mitigates chronic kidney disease through miR-542-3p/HIF-1α/VEGF axis by Luoxiang Qian, Wanru Hu, Yanping Wang, Yousuf Abdulkarim Waheed, Shuqun Hu, Dong Sun, Shulin Li

“…Through in vitro tube formation assays, research demonstrated that knocking down lncRNA TUG1 may enhance angiogenesis and repair damaged endothelial cell-cell connections. …”
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MANAGING MAXILLARY BONE LOSS USING GROWTH FACTORS IN PRE-IMPLANT THERAPY by Cardas Adelina, Stratan Ion, Moraru Daliana, Tibeica Andreea, Agop-Forna Doriana, Norina Forna

“…These factors are pivotal in promoting wound healing, angiogenesis, and the formation of the extracellular matrix. …”
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ADAMTS13 Improves Endothelial Function and Reduces Inflammation in Diabetic Retinopathy by Ahmed M. Abu El-Asrar, Mohd I. Nawaz, Ajmal Ahmad, Mairaj Siddiquei, Eef Allegaert, Lowie Adyns, Lotte Vanbrabant, Priscilla W. Gikandi, Gert De Hertogh, Sofie Struyf, Ghislain Opdenakker

“…Functional studies include the assessment of the blood–retinal barrier (BRB), cell adhesion, and in vitro angiogenesis. In epiretinal membranes, endothelial cells and monocytes/macrophages express ADAMTS13. …”
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