Biomaterial-based strategies: a new era in spinal cord injury treatment by Shihong Zhu, Sijun Diao, Xiaoyin Liu, Zhujun Zhang, Fujun Liu, Wei Chen, Xiyue Lu, Huiyang Luo, Xu Cheng, Qiang Liao, Zhongyu Li, Jing Chen

“…This review elucidates the key mechanisms underlying the occurrence of spinal cord injury and regeneration post-injury, including neuroinflammation, oxidative stress, axon regeneration, and angiogenesis. This review also briefly discusses the critical role of nanodelivery systems used for repair and regeneration of injured spinal cord, highlighting the influence of nanoparticles and the factors that affect delivery efficiency. …”
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Protocol for transcriptomic and epigenomic analyses of tip-like endothelial cells using scRNA-seq and ChIP-seq by Shintaro Funasaki, Yuri Miyamura, Shunsuke Kamei, Akhinur Rahman, Masaya Yamazaki, Shingo Usuki, Keiichiro Yasunaga, Yorifumi Satou, Hiroto Ohguchi, Takashi Minami

“…Summary: Angiogenesis begins as endothelial cells migrate, forming a sprouting tip and subsequent growth-rich stalk cells. …”
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Effect of the Lipoxygenase Inhibitor Baicalein on Muscles in Ovariectomized Rats by D. Saul, J. H. Kling, R. L. Kosinsky, D. B. Hoffmann, M. Komrakova, M. Wicke, B. Menger, S. Sehmisch

“…We conclude that baicalein can stimulate angiogenesis, though not fibre type-specific, in skeletal muscle and reduce the estrogen-related loss of fibre diameter and area in the skeletal muscle in rats. …”
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IFNγ regulates ferroptosis in KFs by inhibiting the expression of SPOCD1 through DNMT3A by Xiuxia Wang, Yating Yang, Xianyu Zhou, Shun Yu, Xusong Luo, Lin Lu, Zhen Gao, Jun Yang

“…Ex-vivo explant keloid culture has also confirmed that the reduction of SPOCD1 helps to reduce the proliferation rate of KFs, inhibit the angiogenesis of keloid scars, and thus inhibit keloid formation. …”
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Different Angiogenic Potential in Low and High Grade Sporadic Clear Cell Renal Cell Carcinoma Is Not Related to Alterations in the von Hippel–Lindau Gene by Marcella M. Baldewijns, Iris J. H. van Vlodrop, Kim M. Smits, Peter B. Vermeulen, Gert G. Van den Eynden, Fiona Schot, Tania Roskams, Hein van Poppel, Manon van Engeland, Adriaan P. de Bruïne

“…In the absence of wild-type pVHL, as observed in VHL patients and most sporadic ccRCCs, constitutive upregulation of HIF results in transcriptional activation of angiogenesis-related genes, such as VEGF. Differences in angiogenic activity within the group of ccRCCs were reported and strong genotype-phenotype correlations were found in patients with VHL disease, raising a question about the importance of VHL inactivation status in angiogenic behaviour and tumour progression.…”
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Hippocampal Neurogenesis and Antidepressive Therapy: Shocking Relations by Peter Rotheneichner, Simona Lange, Anna O’Sullivan, Julia Marschallinger, Pia Zaunmair, Christian Geretsegger, Ludwig Aigner, Sebastien Couillard-Despres

“…Following application of electroconvulsive shocks, intricate interactions between neurogenesis, angiogenesis, and microglia activation, the hypothalamic-pituitary-adrenal axis and the secretion of neurotrophic factors have been documented. …”
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Vascular Endhothelial Growth Factor levels in medium-intensity versus low-intensity exercise with blood flow restriction in elderly women by Nanda Aulya Ramadhan, Damayanti Tinduh, Nuniek Nugraheni, Imam Subadi, Inggar Narasinta, Soenarnatalina Melaniani

“…Vascular Endothelial Growth Factor has a role in angiogenesis and increasing muscle mass through increasing the number and function of satellite cells. …”
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Expression of a Secretory Protein C1qTNF6, a C1qTNF Family Member, in Hepatocellular Carcinoma by Tamotsu Takeuchi, Yoshihiro Adachi, Tomoko Nagayama

“…Conclusion: These results indicate that C1qTNF6 is overexpressed and possibly contributes to tumor angiogenesis by activating the Akt pathway in many hepatocellular carcinomas.…”
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From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents by Hesham M. Hassan, Roket Hassan, Ranya Mohammed Elmagzoub, Ahmed Al-Emam, Konstantinos Kossenas, Ahmed S. Abdel-Samea, Hazim O. Khalifa, Suleyman Akocak, Stefan Bräse, Hamada Hashem

“…It further investigates the mechanisms by which these derivatives fight cancer, such as inducing apoptosis, arresting the cell cycle, inhibiting topoisomerase I and II, preventing tubulin polymerization, suppressing interleukin 6, blocking thymidine phosphorylase, inhibiting multidrug resistance proteins, and hindering angiogenesis. Additionally, it outlines their future directions, such as enhancing their efficacy, selectivity, and investigating potential synergy with other chemotherapeutic agents, offering a promising avenue for developing new therapies for cancer.…”
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Effect of platelet-rich plasma on angiogenic and regenerative properties in patients with critical limb ischemia by Hamid Tanzadehpanah, Sima Nobari, Ava Jalalian Hoseini, Farzaneh Ghotbani, Mohsen Mehrabzadeh, Jamal Jalili shahri, Amirreza Alipour, Mohsen Sheykhhasan, Hamed Manoochehri, Susan Darroudi, Hanie Mahaki

“…Platelet-rich plasma (PRP) is a promising regenerative therapy due to its simplicity, clinical application, safety, and ability to promote angiogenesis. It utilizes various angiogenic growth factors in platelets, including platelet-derived growth factor (PDGF), transforming growth factor-β (TGF-β), insulin-like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF), and epidermal growth factor (EGF), which are integral to the tissue repair.Critical limb ischemia (CLI) is a major symptom of peripheral arterial disease (PAD), and PRP therapy aims to improve blood circulation to the distal limb through the development of blood vessels. …”
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Exploring molecular disparities of H-type vasculature endothelial cells in osteonecrosis of the femoral head through single-cell analysis by Wei Shi, Dong Li, Qian Xu, Kai Zhang, Xinyu Liang, Hui Li, Zhijun Li, Huafeng Zhang

“…Ferroptosis and parthanatos contribute to the demise of H_ECs in ONFH, with pericytes and fibroblasts supporting H_EC angiogenesis.…”
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Synergistic Antitumor Effects of Anlotinib Combined with Oral 5-Fluorouracil/S-1 via Inhibiting Src/AKT Signaling Pathway in Small-Cell Lung Cancer by Xinhang Xia, Wenhu Pi, Yanli Lan, Xiaomai Wu, Dongqing Lv, Yinnan Meng, Haihua Yang, Wei Wang

“…Our data revealed that the treatment of combination of antitumor angiogenesis agent anlotinib with chemotherapy drug 5-FU may have synergistic cytotoxicity to SCLC in vitro and in vivo. …”
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Cancer-associated fibroblasts and their role in tumor progression by M. S. Ermakov, A. A. Nushtaeva, V. A. Richter, O. A. Koval

“…CAFs control tumor angiogenesis, cell motility, tumor immunogenic properties, and the development of resistance to chemo- and immunotherapy. …”
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Angiogenic Response to Major Lung Resection for Non-Small Cell Lung Cancer with Video-Assisted Thoracic Surgical and Open Access by Calvin S. H. Ng, Song Wan, Randolph H. L. Wong, Anthony M. H. Ho, Anthony P. C. Yim

“…Vascular endothelial growth factor (VEGF), angiopoietin 1 (Ang-1), Ang-2, soluble VEGF-receptor 1 (sVEGFR1) and sVEGFR2 may influence angiogenesis. This prospective study examined the influence of open and video-assisted thoracic surgery (VATS) lung resections for early stage non-small cell lung cancer (NSCLC) on postoperative circulating angiogenic factors. …”
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Bifunctional copper ion/melittin incorporated hydrogel with antimicrobial and antioxidant capabilities for infected skin wound healing by Jun Yao, Xiao Li, Minjie Lin, Zhuoqi Han, Xiaonan Wang, Jingjing Guo, Bing Wu, Jiajie Xia

“…In rat models, SA@Cu-MEL significantly accelerated wound healing, enhancing angiogenesis and collagen deposition. The optimised hydrogel not only reduces MEL toxicity but also amplifies its antibacterial and anti-inflammatory effects. …”
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Prognostic significance of mast cell and microvascular densities in malignant peripheral nerve sheath tumor with and without neurofibromatosis type 1 by Roberto André Torres de Vasconcelos, Pedro Guimarães Coscarelli, Thyago Marsicano Vieira, Washington Silva Noguera, Davy Carlos Mendes Rapozo, Marcus André Acioly

“…Diverse mast cell and microvascular distributions suggest that angiogenesis in MPNST occurs independently. The role of mast cells in tumor progression is unclear and lacks prognostic value. …”
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MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis by Junpei Kawamura, Munekazu Yamakuchi, Kentaro Ueno, Teruto Hashiguchi, Yasuhiro Okamoto

“…MiR-25-3p promoted HMVEC-L angiogenesis, proliferation, and migration under hypoxic conditions. …”
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Functional Properties of Human-Derived Mesenchymal Stem Cell Spheroids: A Meta-Analysis and Systematic Review by Sarah Ezquerra, Amparo Zuleta, Rodrigo Arancibia, José Estay, Francisco Aulestia, Flavio Carrion

“…The MSC spheroids properties analyzed that displayed enhancement in comparison with monolayer 2D culture, are stemness, angiogenesis, differentiation potential, cytokine secretion, paracrine and immunomodulatory effects. …”
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Role of proteases in oral carcinogenesis: Insights into the cancer degradome and therapeutic implications by Gargi S. Sarode, Sachin C. Sarode, Urmi Ghone, Rahul Anand

“…These proteases drive tumor invasion, angiogenesis, and metastasis by degrading extracellular matrix components and modulating signaling pathways. …”
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Immunomodulation effects of collagen hydrogel encapsulating extracellular vesicles derived from calcium silicate stimulated-adipose mesenchymal stem cells for diabetic healing by Yen-Hong Lin, Yeh Chen, En-Wei Liu, Mei-Chih Chen, Min-Hua Yu, Cheng-Yu Chen, Chia-Che Ho, Tai-Yi Hsu-Jiang, Jian-Jr Lee, Der-Yang Cho, Ming-You Shie

“…Abstract Diabetic wounds are characterized by chronic inflammation, reduced angiogenesis, and insufficient collagen deposition, leading to impaired healing. …”
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