Autologous Platelet Rich Plasma (PRP) — A Treatment Modality of Neuropathic Ulcers in Leprosy Patients: An Interventional Study by Tejinder Kaur, Sahibpreet Kaur, Gurkim Kaur

“…Use of Autologous platelet-rich plasma (PRP) in trophic ulcers is known to facilitate the restoration of metabolic processes, promotion of neo-angiogenesis, improvement of cellular metabolism, and activation of local immune responses. …”
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Generation of human induced pluripotent stem cell lines from three different male XLRS patients carrying RS1 gene mutation by Sang-Yun Kim, Yong-Min Choi, Yunho Park, Seung-Hyun Kim, Hyun Beom Song, Jeong Hun Kim, Ok-Seon Kwon, Kyung-Sook Chung

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Bufalin targets the SRC-3/c-Myc pathway in chemoresistant cells to regulate metastasis induced by chemoresistance in colorectal cancer by Jinbao Chen, Chenqi Wu, Kun Yu, Jinpei Liu, Jiahua Yang, Wei Li, Xiaoxia Tang, Yihai Shi, Ke Xu, Yi Chen, Xiaoyu Qin

“…Methods The role of BU in the inhibition of EMT and angiogenesis induced by chemoresistant cells using wound healing assays, invasion assays, HUVEC tube formation and adhesion assays. …”
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Does Adiponectin Act as an Antiangiogenic Factor in B-Cell Chronic Lymphocytic Leukemia? by Stefano Molica, Giovanna Digiesi, Angelo Vacca, Rosanna Mirabelli, Katia Todoerti, Caterina Battaglia, Fortunato Morabito, Antonino Neri, Domenico Ribatti

“…Angiogenesis is involved in the pathogenesis of B-cell chronic lymphocytic leukemia (CLL), and high microvascular density has been found in CLL to be associated with a poor prognosis. …”
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Activated Human Umbilical Cord Blood Platelet-Rich Plasma Enhances the Beneficial Effects of Human Umbilical Cord Mesenchymal Stem Cells in Chemotherapy-Induced POF Rats by Jiawei Wang, Yunxiao Zhao, Fengque Zheng, Nana Ma, Rongyan Qin, Weili Qin, Bo Liu, Aiping Qin

“…Subsequently, we tracked the distribution and function of the HucMSCs in POF rats, and the rats’ estrus cycle and serum sex hormones, follicular development, ovarian angiogenesis, ovarian granulosa cell proliferation, and apoptosis were assessed. …”
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Biometabolic Distribution of Tc-3PRGD2 and its Potential Value in Monitoring Chemotherapeutic Effects by Jian-Guo Wu, Shao-Li Song, Xiang Zhou, Fan Wang, Yin-Yan Zhu, Lei Xie, Fan Zhang, Gang Huang

“…Previous studies have reported that 99m Tc-3PRGD2 is an excellent tumor imaging agent that showed a good correlation with integrin α v β 3 , a main factor of tumor-induced angiogenesis. In this study, we investigated the biometabolic distribution characteristics of 99m Tc-3PRGD2 with a continuous dynamic acquisition mode to explore the potential value of 99m Tc-3PRGD2 in monitoring chemotherapeutic effects in VX2 tumor models. …”
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PPARs Mediate Lipid Signaling in Inflammation and Cancer by Liliane Michalik, Walter Wahli

“…In addition, PPARs are tumor growth modifiers, via the regulation of cancer cell apoptosis, proliferation, and differentiation, and through their action on the tumor cell environment, namely, angiogenesis, inflammation, and immune cell functions. …”
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Signal Transduction of Sphingosine-1-Phosphate G Protein—Coupled Receptors by Nicholas Young, James R. Van Brocklyn

“…These receptors are expressed in a wide variety of tissues and cell types, and their cellular effects contribute to important biological and pathological functions of S1P in many processes, including angiogenesis, vascular development, lymphocyte trafficking, and cancer. …”
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Gastrointestinal myofibroblasts: role in regulation of physiological activity and reparation of gastro-intestinal tract by E. F. Barinov, O. N. Sulayeva

“…Morphology, markers, origin and stimulators of development of myofibroblasts, their involvement in formation of microniche for epithelial stem cells, kinetics of tegmental epithelium, angiogenesis, control of vascular permeability is discussed. …”
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Exosomes Derived from CXCR4-Overexpressing BMSC Promoted Activation of Microvascular Endothelial Cells in Cerebral Ischemia/Reperfusion Injury by Xutong Li, Ye Zhang, Yong Wang, Dan Zhao, Chengcheng Sun, Shaoting Zhou, Dongsheng Xu, Jing Zhao

“…The role of ExoCXCR4 in promoting the proliferation and tube formation for angiogenesis and protecting brain endothelial cells was determined in vitro. …”
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Impaired Resolution of Inflammation in the Endoglin Heterozygous Mouse Model of Chronic Colitis by Madonna R. Peter, Mirjana Jerkic, Valentin Sotov, David N. Douda, Daniela S. Ardelean, Niousha Ghamami, Flavia Lakschevitz, Meraj A. Khan, Susan J. Robertson, Michael Glogauer, Dana J. Philpott, Nades Palaniyar, Michelle Letarte

“…We also demonstrate dysregulated expression of BMPER and follistatin, which are extracellular regulators of the TGF-β superfamily that modulate angiogenesis and inflammation. Heightened colonic levels of the neutrophil chemoattractant and proangiogenic factor, CXCL1, were also observed in DSS-treated Eng+/− mice. …”
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Molecular Mechanism of Local Drug Delivery with Paclitaxel-Eluting Membranes in Biliary and Pancreatic Cancer: New Application for an Old Drug by Sookhee Bang, Sung Ill Jang, Su Yeon Lee, Yi-Yong Baek, Jieun Yun, Soo Jin Oh, Chang Woo Lee, Eun Ae Jo, Kun Na, Sugeun Yang, Don Haeng Lee, Dong Ki Lee

“…Local delivery of paclitaxel from a PEM inhibited growth of pancreatic/cholangiocarcinoma tumors in nude mice by suppressing angiogenesis via the mTOR and inducing apoptosis signal pathway.…”
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Wound Management Property of a Hydroethanolic Leaf Extract of Cnestis ferruginea DC by Jibira Yakubu, G. A. Koffuor, Talent Atsu-Nunyawu, Jeremiah Aboagye, Irene Aasam Aabeinir, Fasilatu Alhassan, Lord Christian Ocran, Philomena Entsie

“…There were improved wound tissue reepithelization, fibroblast proliferation, angiogenesis, and collagen deposition with 15% CFHE ointment treatment. …”
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Aberrant Phenotype in Human Endothelial Cells of Diabetic Origin: Implications for Saphenous Vein Graft Failure? by Anna C. Roberts, Jai Gohil, Laura Hudson, Kyle Connolly, Philip Warburton, Rakesh Suman, Peter O’Toole, David J. O’Regan, Neil A. Turner, Kirsten Riches, Karen E. Porter

“…Proliferation, migration, and in vitro angiogenesis assays were performed; western blotting was used to quantify phosphorylation of Akt, ERK, and eNOS. …”
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Anticarcinogenic cationic peptides derived from tryptic hydrolysis of β-lactoglobulin by Eman Ibrahem, Ali Osman, Hefnawy Taha, Mohamed F. Abo El-Maati, Basel Sitohy, Basel Sitohy, Mahmoud Sitohy

“…Treating each cell line with IC50% of the hydrolysate for 24 h increased the apoptosis by enhancing the expression of caspase-9 by 5.66, 7.97, and 3.28 folds over the untreated control and inhibited angiogenesis by reducing VEGFR-2 expression by about 56, 76, and 70%, respectively, indicating strong anticancer and antiangiogenic actions on human cancer cells. …”
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miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma by Enrico Pozzo, Laura Yedigaryan, Nefele Giarratana, Chao-chi Wang, Gabriel Miró Garrido, Ewoud Degreef, Vittoria Marini, Gianmarco Rinaldi, Bernard K. van der Veer, Gabriele Sassi, Guy Eelen, Mélanie Planque, Alessandro Fanzani, Kian Peng Koh, Peter Carmeliet, Jason T. Yustein, Sarah-Maria Fendt, Anne Uyttebroeck, Maurilio Sampaolesi

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Antiangiogenic potential of Elaeagnus umbellata extracts and molecular docking study by targeting VEGFR-2 pathway by Nazir Nausheen, Waqar Arbaz, Zaib Khan Amir, Ali Khan Ayaz, Aziz Tariq, Alasmari Abdullah F.

“…Anti-angiogenesis or inhibition of blood vessel formation is the best way to prevent the growth and metastasis of tumors. …”
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The role of the cytokines IL-27 and IL-35 in cancer by Avner Friedman, Kang-Ling Liao

“…Regulatory T cells produce IL-35 which promotes cancer cells by enhancing angiogenesis, and inhibit CD8$^+$ T cells via TGF-$\beta$ production. …”
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Matrix Metalloproteinases in Inflammatory Bowel Disease: An Update by Shane O’Sullivan, John F. Gilmer, Carlos Medina

“…Through digestion of the extracellular matrix and cleavage of bioactive proteins, a huge diversity of roles have been revealed for the MMPs in IBD, where they have been shown to regulate epithelial barrier function, immune response, angiogenesis, fibrosis, and wound healing. For this reason, MMPs have been recognised as potential biomarkers for disease activity in IBD and inhibition remains a huge area of interest. …”
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Chronic Iliac Vein Occlusion and Painful Nonhealing Ulcer Induced by High Venous Pressures from an Arteriovenous Malformation by Daniel P. Link, Phillip J. Granchi

“…Chronic femoral vein compression (May-Thurner Syndrome) is a known rare cause of deep venous thrombosis. Subsequent angiogenesis and the development of arteriovenous malformation (AVM) in the setting of chronic venous thrombosis is by itself a rare and poorly understood phenomenon. …”
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