Anti-inflammatory coupled anti-angiogenic airway stent effectively suppresses tracheal in-stents restenosis by Yanan Zhao, Yiming Liu, Jiheng Shan, Xiaohong Xu, Chengzhi Zhang, Zaoqu Liu, Xiaomeng Li, Zhaoqian Zhong, Yanxia Gao, Kewei Ren, Dechao Jiao, Jianzhuang Ren, Ping Wu, Yong Jiang, Xinwei Han

“…This study provides insight into the development of airway stents that target angiogenesis and inflammation to address problems associated with TISR effectively and have the potential for clinical translation.…”
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Isolation and Characterization of Human Synovial Fluid-Derived Mesenchymal Stromal Cells from Popliteal Cyst by Fang Li, Jianglin Chen, Mengjia Gong, Yang Bi, Chengchen Hu, Yuanyuan Zhang, Ming Li

“…Several types of human angiogenesis-related proteins were detected in the cell secretory fluid. …”
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The Immunomodulatory Potential of Wharton’s Jelly Mesenchymal Stem/Stromal Cells by Fernanda Vieira Paladino, Juliana de Moraes Rodrigues, Aline da Silva, Anna Carla Goldberg

“…The benefits attributed to mesenchymal stem/stromal cells (MSC) in cell therapy applications are mainly attributed to the secretion of factors, which exhibit immunomodulatory and anti-inflammatory effects and stimulate angiogenesis. Despite the desirable features such as high proliferation levels, multipotency, and immune response regulation, there are important variables that must be considered. …”
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Protective Actions of PPAR-γ Activation in Renal Endothelium by Peter E. Westerweel, Marianne C. Verhaar

“…Proliferation, apoptosis, migration, and angiogenesis by endothelial cells are modulated, but may involve both stimulation and inhibition depending on the specific circumstances. …”
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Combined Effects of Pericytes in the Tumor Microenvironment by Aline Lopes Ribeiro, Oswaldo Keith Okamoto

“…In this review, we highlight the contribution of pericytes to some classical hallmarks of cancer, namely, tumor angiogenesis, growth, metastasis, and evasion of immune destruction, and discuss how collectively these hallmarks could be tackled by therapies targeting pericytes, providing a rationale for cancer drugs aiming at the TME.…”
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PD-L1 knockout or ZG16 overexpression inhibits PDAC progression and modulates TAM polarization by Hui Meng, Manman Nan, Yizhen Li, Yi Ding, Xiaokun Fang, Weiqian Ma, Mingzhi Zhang

“…Meanwhile, we observed a reduction in the M2 marker CD206+, upregulation of immune activation-related cytokines/chemokines, and a decrease in immunosuppressive cytokines and tumor angiogenesis factors. In summary, both PD-L1 knockout and ZG16 overexpression represent promising approaches for PDAC treatment.…”
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The Role of TGFβ Signaling in Squamous Cell Cancer: Lessons from Mouse Models by Adam B. Glick

“…TGFβ1 is a member of a large growth factor family including activins/inhibins and bone morphogenic proteins (BMPs) that have a potent growth regulatory and immunomodulatory functions in normal skin homeostasis, regulation of epidermal stem cells, extracellular matrix production, angiogenesis, and inflammation. TGFβ signaling is tightly regulated in normal tissues and becomes deregulated during cancer development in cutaneous SCC and many other solid tumors. …”
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Emerging Roles of BAI Adhesion-GPCRs in Synapse Development and Plasticity by Joseph G. Duman, Yen-Kuei Tu, Kimberley F. Tolias

“…The brain-specific angiogenesis inhibitor (BAI) subfamily of adhesion G-protein-coupled receptors (adhesion-GPCRs) has recently emerged as central regulators of synapse development and plasticity. …”
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CCL24 and Fibrosis: A Narrative Review of Existing Evidence and Mechanisms by Raanan Greenman, Chris J. Weston

“…Tissue fibrosis results from a dysregulated and chronic wound healing response accompanied by chronic inflammation and angiogenesis. Regardless of the affected organ, fibrosis shares the following common hallmarks: the recruitment of immune cells, fibroblast activation/proliferation, and excessive extracellular matrix deposition. …”
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Leptin Promotes Glioblastoma by Johnathan E. Lawrence, Nicholas J. Cook, Richard A. Rovin, Robert J. Winn

“…Leptin does this through stimulation of cellular pathways that are also advantageous for tumor growth and recurrence: antiapoptosis, proliferation, angiogenesis, and migration. Conversely, a loss of leptin expression attenuates tumor growth. …”
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To Use or Not to Use Metformin in Cerebral Ischemia: A Review of the Application of Metformin in Stroke Rodents by Isaac Arbeláez-Quintero, Mauricio Palacios

“…Most experiments done in the cerebral ischemia model, via middle cerebral artery occlusion in rodents (MCAO), had positive results favoring metformin’s neuroprotective role and involve several cellular pathways like oxidative stress, endothelial nitric oxide synthase activation, activation of angiogenesis and neurogenesis, autophagia, and apoptosis. …”
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The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury by Yanina Tsenkina

“…Additionally, it explores emerging evidence suggesting that 5hmC contributes to neurorepair by promoting neurogenesis, axonal regeneration, angiogenesis, and synaptic plasticity. Understanding the role of hydroxymethylation in cerebrovascular injury provides insights into potential therapeutic approaches for enhancing the brain’s innate mechanisms for protection and repair. …”
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Research progress of HIF-1a on immunotherapy outcomes in immune vascular microenvironment by Shaoyan Shi, Xuehai Ou, Chao Liu, Hao Wen, Jiang Ke

“…HIF-1α-mediated tumor hypoxia drives angiogenesis, immune suppression, and extracellular matrix remodeling, creating an environment that promotes tumor progression and resistance to immunotherapies. …”
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Tissue Factor, Blood Coagulation, and Beyond: An Overview by Arthur J. Chu

“…TF overexpression/hypercoagulability often observed in many clinical conditions certainly expands its role in proinflammation, diabetes, obesity, cardiovascular diseases, angiogenesis, tumor metastasis, wound repairs, embryonic development, cell adhesion/migration, innate immunity, infection, pregnancy loss, and many others. …”
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Anti-tumor role and molecular mechanism of vanillic acid by Xunxing Hao, Zhixiao Gao, Mingzhe Hu

“…Furthermore, VA disrupts the cancer cell cycle, arresting most cancer cells at the G1 phase, curtails cell migration, invasion, angiogenesis, and potentiates the therapeutic efficacy of chemotherapeutic drugs, all while minimizing adverse reactions. …”
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Inhibitory Effects of Antimicrobial Peptides on Lipopolysaccharide-Induced Inflammation by Yue Sun, Dejing Shang

“…In addition, AMPs also modulate the host immune system by chemotaxis of leukocytes, to promote immune cell proliferation, epithelialization, and angiogenesis and thus play a protective role. This review summarizes some recent researches about anti-inflammatory AMPs, with a focus on the interaction of AMPs and LPS on the past decade.…”
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Extracellular vesicles—a new player in the development of urinary bladder cancer by Damian Kasiński, Kamil Szeliski, Tomasz Drewa, Marta Pokrywczyńska

“…The cargo carried by EVs can also induce angiogenesis, another critical element in the development of bladder cancer, and modulate the immune system response in a tumor-beneficial manner. …”
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The Role of Exosomes in Cancer Progression and Therapy by Shynggys Sergazy, Roza Seydahmetova, Alexandr Gulyayev, Zarina Shulgau, Mohamad Aljofan

“…Interestingly, tumor-derived exosomes carry oncogenic molecules, such as proteins and microRNAs, which can reprogram recipient cells, promote angiogenesis, and stimulate cancer pre-metastatic niche, supporting cancer growth and metastasis. …”
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Promising Markers in the Context of Mesenchymal Stem/Stromal Cells Subpopulations with Unique Properties by Agnieszka Smolinska, Aleksandra Bzinkowska, Paulina Rybkowska, Magdalena Chodkowska, Anna Sarnowska

“…Such populations differ in specialization degree, proliferation, and immunomodulatory properties or exhibit other additional properties such as increased angiogenesis capacity. In this review article, we attempted to identify such outstanding populations according to the specific surface antigens or intracellular markers. …”
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Exosomes in Oral Diseases: Mechanisms and Therapeutic Applications by Miao Q, Li S, Lyu W, Zhang J, Han Y

“…In OSCC tumor-derived exosomes promote cancer progression through cell proliferation, migration, invasion, and angiogenesis, and serve as potential biomarkers for early diagnosis and prognosis. …”
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