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241
Physiological premature aging of ovarian blood vessels leads to decline in fertility in middle-aged mice
Published 2025-01-01“…Utilizing genetic-modified mouse models, we demonstrate that granulosa cell secreted VEGFA governs ovarian angiogenesis, but the physiological decline in oBV is not attributed to VEGFA insufficiency. …”
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242
Ferrostatin-1 inhibits osteoclast differentiation and prevents osteoporosis by suppressing lipid peroxidation
Published 2025-01-01“…The capacity for osteogenesis and angiogenesis of cells after treatment with supernatant of BMMs was evaluated. …”
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243
Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells
Published 2022-01-01“…The proliferation, migration, apoptosis, and angiogenesis were tested by cell counting kit-8 (CCK-8) assay, Transwell assay, flow cytometry analysis, and in vitro tube formation assay. …”
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244
Efek Latihan Fisik Terhadap Remodeling Jantung
Published 2019-05-01“…Pada dasarnya ada dua cara untuk membedakan antara hipertrofi jantung fisiologis dan patologis: remodeling LV patologis disertai dengan disfungsi LV (baik diastolik, sistolik, atau keduanya) dan meningkatnya ketidakseimbangan antara massa otot dengan angiogenesis, sedangkan remodeling LV fisiologis meningkatkan fungsi ventrikel dan terdapat keseimbangan antara pertumbuhan massa otot dan angiogenesis. …”
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245
Development of Anti-VEGF Therapies for Intraocular Use: A Guide for Clinicians
Published 2012-01-01“…Angiogenesis is the process by which new blood vessels form from existing vessel networks. …”
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246
Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis
Published 2012-01-01“…In the 1970s, the late Judah Folkman postulated that tumors grow proportionately to their blood supply and that tumor angiogenesis removed this limitation promoting growth and metastasis. …”
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247
Proangiogenic Features of Mesenchymal Stem Cells and Their Therapeutic Applications
Published 2016-01-01“…This review will focus on recent progresses on endothelial differentiation and potential clinical application of MSCs, with emphasis on therapeutic angiogenesis for treatment of cardiovascular diseases.…”
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248
Sorafenib-Associated Heart Failure Complicated by Cardiogenic Shock after Treatment of Advanced Stage Hepatocellular Carcinoma: A Clinical Case Discussion
Published 2017-01-01“…Inhibition of VEGF signaling interrupts angiogenesis and is associated with the development of hypertension and compensatory hypertrophy. …”
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249
Harnessing the Angiogenic Potential of Stem Cell-Derived Exosomes for Vascular Regeneration
Published 2016-01-01“…The current gain of insight in exosomes studies highlights the power of combining cell based therapies and their secreted products in therapeutic angiogenesis.…”
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250
Metformin Suppressed CXCL8 Expression and Cell Migration in HEK293/TLR4 Cell Line
Published 2017-01-01“…CXCL8 promotes tumor microenvironment construction through recruiting leukocytes and endothelial progenitor cells that are involved in angiogenesis. It also enhances tumor cell proliferation and migration. …”
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251
Exploring the Mechanism of Microarteriogenesis in Porous Silk Fibroin Film
Published 2012-01-01“…Based on the experiment of the microarteriogenesis that is associated with angiogenesis during tissue repair process in porous silk fibroin films (PSFFs), we investigate the characteristics of micro-arteriogenesis and explore its mechanism. …”
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252
The Role of PDGFs and PDGFRs in Colorectal Cancer
Published 2017-01-01“…Colorectal cancer (CRC) is an important cause of morbidity and mortality worldwide. Angiogenesis was reported as one important mechanism activated in colorectal carcinogenesis. …”
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253
Beta-adrenergic blocking agents in cutaneous and oral melanoma
Published 2024-06-01“…Studies suggest beta-blockers might reduce cutaneous melanoma progression by inhibiting angiogenesis and tumor cell proliferation, improving survival rates. …”
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254
Impaired Muscle Regeneration in Ob/ob and Db/db Mice
Published 2011-01-01“…Muscle regeneration was delayed in ob/ob and db/db mice, but not in a less severe model of insulin resistance – feeding a high-fat diet to wild-type mice. Angiogenesis, cell proliferation, and myoblast accumulation were also impaired in ob/ob and db/db mice, but not the high-fat diet mice. …”
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255
In Vivo Bioluminescence Imaging Validation of a Human Biopsy–Derived Orthotopic Mouse Model of Glioblastoma Multiforme
Published 2013-05-01“…Glioblastoma multiforme (GBM), the most aggressive brain malignancy, is characterized by extensive cellular proliferation, angiogenesis, and single-cell infiltration into the brain. …”
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256
Mesenchymal Stem Cell–derived Extracellular Vesicles: An Emerging Therapeutic Strategy for Diabetic Wound Healing
Published 2024-12-01“…They help prevent damaged cells from dying, revitalize senescent cells, and boost angiogenesis. MSC-EVs can be a safe, effective and ethical therapy for DFU by increasing M2 macrophages polarization, improving the proliferation, reducing scar, and improving angiogenesis. …”
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257
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Endothelial tip-cell position, filopodia formation and biomechanics require BMPR2 expression and signaling
Published 2025-01-01“…Abstract Blood vessel formation relies on biochemical and mechanical signals, particularly during sprouting angiogenesis when endothelial tip cells (TCs) guide sprouting through filopodia formation. …”
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259
Inflammatory Mediators and Angiogenic Factors in Choroidal Neovascularization: Pathogenetic Interactions and Therapeutic Implications
Published 2010-01-01“…Although the term may suggest just a vascular pathological condition, CNV is more properly definable as an aberrant tissue invasion of endothelial and inflammatory cells, in which both angiogenesis and inflammation are involved. Experimental and clinical evidences show that vascular endothelial growth factor is a key signal in promoting angiogenesis. …”
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260
A structural model of the VEGF signalling pathway: Emergence of robustness and redundancy properties
Published 2012-11-01“…Angiogenesis has been recognized as a key stage for cancer development and metastasis. …”
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