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241
The role of the cytokines IL-27 and IL-35 in cancer
Published 2015-07-01“…Regulatory T cells produce IL-35 which promotes cancer cells by enhancing angiogenesis, and inhibit CD8$^+$ T cells via TGF-$\beta$ production. …”
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242
Matrix Metalloproteinases in Inflammatory Bowel Disease: An Update
Published 2015-01-01“…Through digestion of the extracellular matrix and cleavage of bioactive proteins, a huge diversity of roles have been revealed for the MMPs in IBD, where they have been shown to regulate epithelial barrier function, immune response, angiogenesis, fibrosis, and wound healing. For this reason, MMPs have been recognised as potential biomarkers for disease activity in IBD and inhibition remains a huge area of interest. …”
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243
Chronic Iliac Vein Occlusion and Painful Nonhealing Ulcer Induced by High Venous Pressures from an Arteriovenous Malformation
Published 2011-01-01“…Chronic femoral vein compression (May-Thurner Syndrome) is a known rare cause of deep venous thrombosis. Subsequent angiogenesis and the development of arteriovenous malformation (AVM) in the setting of chronic venous thrombosis is by itself a rare and poorly understood phenomenon. …”
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244
Gastrointestinal Microbiota and Some Children Diseases: A Review
Published 2012-01-01“…A balance between pathogenic and beneficial microbiota throughout childhood and adolescence is important to gastrointestinal health, including protection against pathogens, inhibition of pathogens, nutrient processing (synthesis of vitamin K), stimulation of angiogenesis, and regulation of host fat storage. Probiotics can promote an intentional modulation of intestinal microbiota favoring the health of the host. …”
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245
Oxidative Stress, Tumor Microenvironment, and Metabolic Reprogramming: A Diabolic Liaison
Published 2012-01-01“…Oxidants influence the DNA mutational potential, intracellular signaling pathways controlling cell proliferation and survival and cell motility and invasiveness as well as control the reactivity of stromal components that is fundamental for cancer development and dissemination, inflammation, tissue repair, and de novo angiogenesis. This paper is focused on the role of oxidant species in the acquisition of two mandatory features for aggressive neoplastic cells, recently defined by Hanahan and Weinberg as new “hallmarks of cancer”: tumor microenvironment and metabolic reprogramming of cancer cells.…”
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246
The Role of Decorin in Autoimmune and Inflammatory Diseases
Published 2022-01-01“…Decorin has been shown to be involved in wound repair, cell cycle, angiogenesis, tumor metastasis, and autophagy. Recent evidence indicates that it also plays a role in immune regulation and inflammatory diseases. …”
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247
Diabetic Ephrin-B2-Stimulated Peripheral Blood Mononuclear Cells Enhance Poststroke Recovery in Mice
Published 2018-01-01“…Infarct volume, neurological deficit, neurogenesis, angiogenesis, and inflammation were investigated as were the potential mechanisms of PB-MNC+ cells in poststroke neurorepair. …”
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248
Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry
Published 2025-02-01“…These results suggest that iHDAC inhibitors may modulate or suppress tumor behavior growth by targeting ECM proteins’ secretion rather than directly inhibiting angiogenesis.…”
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249
Impact of Nutritional Factors on Colorectal Cancer: Implication the molecular mechanisms of Vitamins Supplementation
Published 2025-01-01“…We reviewed the published significance of vitamin supplementation on colorectal cancer proliferation, survival, apoptosis, angiogenesis and migration, focusing on the possible molecular mechanisms of water-soluble and fat-soluble vitamins to provide protective suggestions to minimize the occurrence and progression of colorectal cancer. …”
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250
The Role of Hypoxia in Orthodontic Tooth Movement
Published 2013-01-01“…Because upregulated tissue proliferation rates are often accompanied by angiogenesis, hypoxia may be assumed to fundamentally contribute to bone remodeling processes during orthodontic treatment.…”
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251
The Use of Adipose-Derived Stem Cells in Selected Skin Diseases (Vitiligo, Alopecia, and Nonhealing Wounds)
Published 2017-01-01“…ADSCs seem to be the ideal cell population for the use in regenerative medicine due to their easy isolation, nonimmunogenic properties, multipotential nature, possibilities for differentiation into various cell lines, and potential for angiogenesis. This article reviews the current data on the use of ADSCs in the treatment of vitiligo, various types of hair loss, and the healing of chronic wounds.…”
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252
Use of Platelet Rich Plasma in the Treatment of Diabetic Foot. Case Report
Published 2024-09-01“…An alternative for its treatment is the use of platelet-rich plasma due to its ability to stimulate angiogenesis, cell proliferation and collagen synthesis. …”
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253
Restenosis and Therapy
Published 2012-01-01“…Gene therapy and therapeutic angiogenesis is proposed for therapy in restenosis. We suggest a drug candidate (iroxanadine), which ensures a noninvasive treatment by reverse regulation of the highly proliferating VSMCs and the disturbed function of ECs.…”
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254
Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma
Published 2012-01-01“…Its presence seems to be linked with HCC progression, possibly via facilitating angiogenesis. The origin of tumor-associated may be related to the gut, in which the differentiation of T cells, especially cells, is affected by microbiota. …”
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255
Advanced construction strategies to obtain nanocomposite hydrogels for bone repair and regeneration
Published 2024-03-01“…Abstract Bone tissue engineering is pivotal in facilitating bone reconstruction by promoting persistent angiogenesis and osteogenesis. Initially, the hot gel composite hydrogel scaffold technique was employed. …”
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256
Hyperbaric Oxygen Therapy of an Adolescent Stem Cell Transplantation Recipient with Hemorrhagic Cystitis and BK Virus
Published 2020-01-01“…Hyperbaric oxygen therapy (HBOT) continues to show effectiveness in the treatment of several diseases and benefits such as fibroblast proliferation, capillary angiogenesis, and decreasing edema, especially in hemorrhagic cystitis (HC). …”
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257
Skin Acute Wound Healing: A Comprehensive Review
Published 2019-01-01“…Fibroplasia, reepithelialization, angiogenesis, and peripheral nerve repair are the central actions of this phase. …”
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258
From hypoxic pockets to daily routines: linking brain oxygenation and cognitive resilience
Published 2025-01-01“…These transient oxygen-deprived microenvironments play a pivotal role in neurovascular coupling, synaptic plasticity, and angiogenesis, processes crucial for maintaining cognitive resilience and neuronal health. …”
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259
Tumor Cells and Tumor-Associated Macrophages: Secreted Proteins as Potential Targets for Therapy
Published 2011-01-01“…Tumor-associated macrophages (TAMs), which constitute a significant part of the tumor-infiltrating immune cells, have been linked to the growth, angiogenesis, and metastasis of a variety of cancers, most likely through polarization of TAMs to the M2 (alternative) phenotype. …”
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260
Management of a Patient with Metastatic Colorectal Cancer and Liver Metastases
Published 2014-01-01“…., FOLFOX) in combination with biologic agents that target angiogenesis (e.g., bevacizumab). For patients with progression following first-line treatment, current second-line options include a change in chemotherapy with bevacizumab (for patients who did or did not receive prior bevacizumab) or FOLFIRI in combination with aflibercept, a more recently approved antiangiogenesis therapy. …”
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