Editorial: Preclinical animal models and measures of pain: improving predictive validity for analgesic drug development - volume II by Anke Tappe-Theodor, Thomas J. Martin, S. Stevens Negus

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Outcomes of an Emergency Department opioid alternatives Program implemented within a safety-net hospital system by Magda Montague, Charlotte Hopson, Claire Layton, Jennifer Fishe, Ashley Norse, L. Kendall Webb, Petra Duran-Gehring, Andrew Bertrand, Jennifer Brailsford, Taylor Munson, Rui Wang, Nolan Menze, Katelyn Perl, Phyllis Hendry, Sophia Sheikh

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Examining the Effects of Tramadol, on the WADA Prohibited List, on Sports Performance by Cemre Acar Halıcı, Aysun Hacışevki

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Computer Simulation on Analgesic Functional Chemome Characteristics of <italic>Radix Saposhnikoviae</italic> by Chunsong ZHENG, Xiaojie XU, Hongzhi YE, Jinxia YE, Guangwen WU, Xianxiang LIU

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NURSES AND PAIN MANAGEMENT IN TERRITORIAL HEALTH EMERGENCIES: A RETROSPECTIVE STUDY by Federico Pecetta, Gian Domenico Giusti, Sara Staffaroni, Matteo Ricci

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Comprehensive metabolite profiling and evaluation of anti-nociceptive and anti-inflammatory potencies of Nypa fruticans (Wurmb.) leaves: Experimental and in-silico approaches by Farhana Islam, Md. Aktaruzzaman, Md. Tarikul Islam, Fariya Islam Rodru, Saquiba Yesmine

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Commentary: The immediate pain relief of low-level laser therapy for burning mouth syndrome: a retrospective study of 94 cases by Takayuki Suga, Akira Toyofuku

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Opioid Prescribing Trends by Croatian Dentists - Is there a Reason for Concern? by Lara Vranić, Krešimir Bašić, Ivana Šutej

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The bioguided fractionation and pharmacological activity of an endemic Salix canariensis species by Gutiérrez Sandra Dévora, Kuri Susana Abdala, Martín-Herrera Domingo

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Acute pain management in the trauma patient population: are we doing enough? A prospective observational study by Segni Kejela, Nebyou Seyoum

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Discrimination between unstable angina stages using multiple pathway parameters by Hasan Abbas Qazmooz, Hasan Najah Smesam, Maha Abdul Saheb Ridha, Hussein Al-Hakeim

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EXPERIMENTAL ESTIMATION OF THE ANALGESIC EFFECT AT COMBINED INFLUENCE OF THE ELECTROSTIMULATION AND THE PERCUSSIVE-FRICTIONAL MASSAGE AND IMPULSE CURRENTS REGISTRATION by M. G. Kiselev, E. I. Labun

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A Comparative Analysis of Regional and Local Anesthesia in Arteriovenous Fistula Surgery: A Single-Center Study by Mustafa Cüneyt Çiçek

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Paracetamol did not improve the analgesic efficacy with regional block after video assisted thoracoscopic surgery: a randomized controlled trial by Sujin Kim, Seung Woo Song, Haesung Lee, Chun Sung Byun, Ji-Hyoung Park

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Analgesic effect of ethylacetate fraction of the methanol leaves extract of Hannoa klaineana in rats by Ibrahim Abubakar, Mu'azu Abubakar Gusau, Jabir Aliyu Danyaya, Shehu Ibrahim, Zayyanu Abdullahi, Abdulhakim Zubairu, Abdulsalam Umar Sahabi

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Self-medication pattern among medical students in Middle Delta, Egypt by Nadira Mansour Hassan, Shimaa Mohamed Mohamed Koabar

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A Multimodal Approach to Analgesia in Anorectal Surgery by T. N. Garmanova, D. R. Markaryan, E. A. Kazachenko, A. M. Lukianov, M. A. Kazachenko, M. A. Agapov

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Therapeutic alliance impact on analgesic outcomes in a real-world clinical setting: An observational study by Barrachina Jordi, Margarit César, Andreu Blanca, Zandonai Thomas, Ballester Pura, Muriel Javier, Cutillas Esperanza, Peiró Ana M.

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Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel by João B. Calixto, Adara Aurea dos Santos, Juliano Ferreira, Alessandra Hubner Souza, Célio José de Castro Junior, Marcus Vinicius Gomez

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