Alterations in the Processing of Platelet APP (Amyloid Beta Precursor Protein) in Alzheimer Disease: The Possible Nexus by Hayder M. Al‐kuraishy, Ghassan M. Sulaiman, Hamdoon A. Mohammed, Retaj A. Dawood, Ali K. Albuhadily, Ali I. Al‐Gareeb, Mosleh M. Abomughaid, Daniel J. Klionsky

Subjects: Get full text

Fool's gold standard? Immunoperoxidase staining with the mouse monoclonal antibody (Clone 22C11) for detecting axonal pathology after traumatic brain injury by Guoxiang Xiong, Shanti R. Tummala, Akiva S. Cohen, Akiva S. Cohen

Subjects: Get full text

APP β-CTF triggers cell-autonomous synaptic toxicity independent of Aβ by Mengxun Luo, Jia Zhou, Cailu Sun, Wanjia Chen, Chaoying Fu, Chenfang Si, Yaoyang Zhang, Yang Geng, Yelin Chen

Subjects: Get full text

Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models by Lisa Blackmer-Raynolds, Lyndsey D. Lipson, Isabel Fraccaroli, Ian N. Krout, Jianjun Chang, Timothy Robert Sampson

Subjects: Get full text

Deletion of Murine APP Aggravates Tau and Amyloid Pathologies in the 5xFADXTg30 Alzheimer’s Disease Model by Kunie Ando, Andreea-Claudia Kosa, Yasmina Mehadji, Hinde Lasri, Lidia Lopez-Gutierrez, Carolina Quintanilla-Sánchez, Emmanuel Aydin, Emilie Doeraene, Alain Wathelet-Depauw, Siranjeevi Nagaraj, Jean-Pierre Brion, Karelle Leroy

Subjects: Get full text

The role of intracellular and extracellular copper compartmentalization in Alzheimer’s disease pathology and its implications for diagnosis and therapy by Yu-Qi Li, Yu-Qi Li, Shuang-Shuang Tan, Shuang-Shuang Tan, Di Wu, Di Wu, Qian Zhang, Tao Wang, Gang Zheng

Subjects: Get full text

The bidirectional effects of APPswe on the osteogenic differentiation of MSCs in bone homeostasis by regulating Notch signaling by Nan Wang, Xiaoyu Shen, Huakun Huang, Runhan Zhao, Habu Jiwa, Zongxin Li, Pei Li, Jixing Ye, Qiang Zhou

Subjects: Get full text

ADVANCEMENT IN THE TREATMENT OF ALZHEIMER'S DISEASE, 2023 by Anum Safdar, Muhammad Usman Ghani, Muhammad Farooq Sabar, Muhammad Umer Khan, Mureed Hussain, Khuram aziz, Taha Hussain

Subjects: Get full text

Targeting Iron Responsive Elements (IREs) of APP mRNA into Novel Therapeutics to Control the Translation of Amyloid-β Precursor Protein in Alzheimer’s Disease by Mateen A. Khan

Subjects: Get full text

The structure of an amyloid precursor protein/talin complex indicates a mechanical basis of Alzheimer’s disease by Charles Ellis, Natasha L. Ward, Matthew Rice, Neil J. Ball, Pauline Walle, Chloé Najdek, Devrim Kilinc, Jean-Charles Lambert, Julien Chapuis, Benjamin T. Goult

Subjects: Get full text

Fatty acid synthase inhibitor cerulenin hinders liver cancer stem cell properties through FASN/APP axis as novel therapeutic strategies by Liang-Yun Chen, Dao-Sian Wu, Yao-An Shen

Subjects: Get full text

Establishment of a Rat Model of Alzheimer's Disease by Introducing Human Triple Mutant APP Gene into Hippocampus via Brain Stereotactic Technology by XIAO Linlin, YANG Yixuan, LI Shanshan, LUO Lanshiyu, YIN Siwei, SUN Juming, SHI Wei, OUYANG Yiqiang, LI Xiyi

Subjects: Get full text

The autocrine motility factor receptor delays the pathological progression of Alzheimer’s disease via regulating the ubiquitination-mediated degradation of APP by Jingjing Zhang, Congcong Liu, Jing Liu, Yuting Cui, Yuli Hou, Qiao Song, Xiaomin Zhang, Xiaoling Wang, Qian Zhang, Min Cao, Wenchao Wang, Peichang Wang, Yaqi Wang

Subjects: Get full text

Effects of West Nile virus on behavioral and cognitive performance, cortical Aβ pathology, viral loads, and immune measures of middle-aged NL-G-F/E3 and NL-G-F/E4 mice by Abigail O’Niel, Christopher J. Parkins, Alexandra Pederson, Elizabeth Saltonstall, Emily Bunnell, Ria Aggarwal, Phoebe Sandholm, Kat Kessler, Henry F. Harrison, Jessica L. Smith, Alec J. Hirsch, Jacob Raber, Jacob Raber, Jacob Raber, Jacob Raber

Subjects: Get full text

New insights into the 17β-hydroxysteroid dehydrogenase type 10 and amyloid-β 42 derived cytotoxicity relevant to Alzheimer’s disease by Aneta Houfková, Monika Schmidt, Ondřej Benek, Ivo Fabrik, Rudolf Andrýs, Lucie Zemanová, Ondřej Soukup, Kamil Musílek

Subjects: Get full text

Potential Roles of Hypoxia-Inducible Factor-1 in Alzheimer’s Disease: Beneficial or Detrimental? by Tsu-Kung Lin, Chi-Ren Huang, Kai-Jung Lin, Yi-Heng Hsieh, Shang-Der Chen, Yi-Chun Lin, A-Ching Chao, Ding-I Yang

Subjects: Get full text

Iron responsive elements mRNA regulate Alzheimer’s amyloid precursor protein translation through iron sensing by Mateen A. Khan

Subjects: Get full text

Cell-specific Nav1.6 knockdown reduced astrocyte-derived Aβ by reverse Na+-Ca2+ transporter-mediated autophagy in alzheimer-like mice by Xin Wang, Wei Wu, Guang Yang, Xue-Wei Yang, Xu Ma, Dan-Dan Zhu, Kabir Ahmad, Khizar Khan, Ying-Zi Wang, Ao-Ran Sui, Song-Yu Guo, Yue Kong, Bo Yuan, Tian-Yuan Luo, Cheng-Kang Liu, Peng Zhang, Yue Zhang, Qi-Fa Li, Bin Wang, Qiong Wu, Xue-Fei Wu, Zhi-Cheng Xiao, Quan-Hong Ma, Shao Li

Subjects: Get full text

A Bilingual Nanobiosensor for Cross‐Category Integrated Decoding of the Beta‐Site Amyloid Precursor Protein‐Cleaving Enzyme 1–Aβ Oligomer Signaling Pathway by Tao Cheng, Peifen Lu, Yixi Dong, Jiabao Yu, Gang Wang, Jianwei Jiao, Peng Miao, Jin Jiao

Subjects: Get full text