Ischemic Stroke and Ruptured Mycotic Aneurysm, Two Complications of Infective Endocarditis in One Patient by Alassane Mamadou Diop, Ahmadou Bamba Mbodj, Serigne Abdou Aziz Fall, Ibrahima Niang

“…MRI showed infarcts in both cerebral hemispheres, and the TOF sequence showed an amputation of M2. On transesophageal ultrasound, there was evidence of vegetations at the mitral valve. …”
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Clostridial myonecrosis. A Case Report by Ledys Pérez Morales, Hidaleysi Quintana Hernández, Jorge E. Barletta del Castillo

“…Gas gangrene was diagnosed, resulting in member amputation. <em>Clostridium perfringens</em> was isolated from the wound. …”
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Distal Femur Type III Open Fractures: Functional Outcome Analysis by Arul R Bhagyaraj, Anand Ashok, Manisha J Kumar, Krupakaran Ganesan, Anand Kurian, Dan B Inja, Manasseh Nithyananth, Vinoo M Cherian, Jeremy Bliss

“…About 11% of patients had vascular injuries, all of whom underwent amputation. The high velocity of injury correlated with poor knee range of movements (<i>p</i>-value of 0.030). …”
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Treatment of a Vertical Root Fracture Using Dual-Curing Resin Cement: A Case Report by Nima Moradi Majd, Farshid Akhtari, Solmaz Araghi, Hamed Homayouni

“…The prognosis of the root with VRF is poor therefore tooth extraction and root amputation are usually the only treatment options. However, bonding of the fracture line with adhesive resin cement during the intentional replantation procedure was recently suggested as an alternative to tooth extraction. …”
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Nanomaterials in wound infeetion care for senile diabetes: current research and developments by Yiran Liu, Xue Bai, Hui Ren, Baofeng Guo

“…Wound infections in elderly diabetic patients represent a severe complication of diabetes, with diabetic foot ulcers being the most common manifestation.Due to impaired immune function and the prolonged course of the disease, elderly patients often struggle to control wound infections, leading to increased medical costs, extended hospital stays, higher rates of amputation and mortality.As bacterial resistance becomes more prevalent, traditional oral or intravenous antibiotics are increasingly ineffective in treating wound infections in elderly diabetic patients.In contrast, emerging nanomaterials offer promising prospects in antibacterial therapy, owing to their superior biocompatibility, targeted action, controlled release, and low toxicity.This article reviews the latest research on the antibacterial mechanisms of nanomaterials and explores their potential as a novel strategy for treating wound infections in elderly diabetic patients.…”
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Expandable Total Humeral Replacement in a Child with Osteosarcoma by Eric R. Henderson, Jidi Gao, John Groundland, Odion Binitie, G. Douglas Letson

“…A right-handed 8-year-old female patient presented with a conventional, high-grade osteosarcoma involving her right humerus; through-shoulder amputation was recommended. After consultation, total humerus resection with expandable, total humeral endoprosthesis reconstruction was performed with a sleeve to encourage soft-tissue ingrowth. …”
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The correlation between high-sensitivity cardiac troponin levels in diabetic patients’ serum and lower limb lesions: based on NHANES data by Lin Li, Linxi Jiao, Danyang Yang, Jingxia Zhao, Ping Li

“…Logistic regression was used to assess the association of hs-cTnT with lower extremity disease, including peripheral neuropathy (as assessed by monofilament test), peripheral artery disease (as assessed by ankle-brachial index), history of foot ulcers, or amputation. All analyses are weighted.ResultsThe prevalence rate of diabetic lower extremity disease was 41.6%. …”
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The Burden of Vibrio sp. Infections – A Scoping Review by Ke-Yan Loo, Jodi Woan-Fei Law, Loh Teng-Hern Tan, Priyia Pusparajah, Sunny Hei Wong, Kok-Gan Chan, Learn-Han Lee, Vengadesh Letchumanan

“…V. cholerae causes cholera which may result in severe dehydration and death without timely treatment, V. parahaemolyticus infection causes gastroenteritis while V. vulnificus infections typically manifest as wound or soft tissue infections with poor prognosis, including amputation or death. Available data on the epidemiology and clinical burden of Vibrio infections were compiled systematically following a literature review, and 149 relevant studies published between 2010 to 2022 were identified. …”
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Ozone therapy as support in the treatment of diabetic foot ulcer. A case report by Isidro Matos Lamote, Jorge Enrique Rodríguez León, Carlos García Arencibia, Maydelin Pérez Reina

“…In the absence of satisfactory evolution, new debridement was performed, with amputation of the third and fourth toes of the left foot; the initial treatment was resumed, this time combined with local and rectal ozone therapy. …”
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Mycotic Renal Artery Aneurysm Presenting as Critical Limb Ischemia in Culture-Negative Endocarditis by Vy Thuy Ho, Nathan K. Itoga, Tiffany Wu, Ehab Sorial, Manuel Garcia-Toca

“…The patient underwent primary resection and repair of the aneurysm, aortic valve replacement, and left below-knee amputation after bilateral common iliac and left superficial femoral artery stenting. …”
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Necrotizing Soft Tissue Infection Occurring after Exposure to Mycobacterium marinum by Shivani S. Patel, M. Lance Tavana, M. Sean Boger, Soe Soe Win, Bassam H. Rimawi

“…While previous cases of necrotizing soft tissue infections related to M. marinum have been documented, the importance of our presenting case is to illustrate the aggressive nature of M. marinum resulting in a persistent necrotizing soft tissue infection of a finger that required multiple aggressive wound debridements, followed by an amputation of the affected extremity, in order to hasten recovery.…”
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High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb by Tiffany J. Pan, Liron Pantanowitz, Kurt R. Weiss

“…We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. …”
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Umbilical Cord-Derived Mesenchymal Stem Cells Relieve Hindlimb Ischemia through Enhancing Angiogenesis in Tree Shrews by Cunping Yin, Yuan Liang, Jian Zhang, Guangping Ruan, Zian Li, Rongqing Pang, Xinghua Pan

“…Patients suffer from consequent rest pain, ulcers, cool limbs, and even amputation. Angiogenesis is a promising target for the treatment of ischemic limbs, providing extra blood for the ischemic region. …”
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Association Between Smoking and Foot Ulcer among Patients with Diabetes Mellitus, Wad Medani, Sudan by Abeer AbdElrahman Elnour Eltilib

“…Conclusion: Extensive awareness programs to control the negative effect of smoking in accelerating DFU and amputation are necessary. …”
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Infected Osteoclastoma of the Knee: An Unusual Presentation by O. B. Pattanashetty, B. B. Dayanand, Yogesh Mapari, Monish Bami

“…She was treated successfully with above knee amputation. The tissue was sent for histopathology which confirmed osteoclastoma. …”
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Neck of Femur Fracture in a Patient with a Chronic Osteomyelitis of the Ipsilateral Foot by Anne-Carolin Döring, Anne J. H. Vochteloo, Kees van Doorn, Rianne M. H. A. Huis in ’t Veld, Anil Peters

“…In our case, a below-knee amputation was performed first, followed by total hip arthroplasty two weeks later. …”
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Biomechanic and Energetic Effects of a Quasi-Passive Artificial Gastrocnemius on Transtibial Amputee Gait by Michael F. Eilenberg, Ken Endo, Hugh Herr

“…Two participants with unilateral transtibial amputation walk with this prosthesis on an instrumented treadmill, while motion, force, and metabolic data are collected. …”
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Emerging strategies for nitric oxide production and their topical application as nanodressings to promote diabetic wound healing by Dan Xia, Ying Guo, Ruodan Xu, Ning Li

“…Abstract The challenges associated with prolonged healing or non-healing of chronic diabetic wounds contribute significantly to the increased incidence of lower limb amputation. A pivotal factor in the impediment of healing is the reduced production of endogenous nitric oxide (NO) due to the hyperglycemic microenvironment typical of chronic diabetes. …”
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Treatment of an Intractable Forefoot Ulcer Using Realignment Osteotomy in a Patient with Rheumatoid Arthritis by Makoto Imai, Naoki Kondo, Rei Kumazaki, Naoto Endo

“…We proceeded with surgical correction of the forefoot alignment, including shortening oblique osteotomy of metatarsals 2 through 5, rather than amputation of the 5th digit. Following surgery, targeted antibiotic treatment was provided. …”
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Anesthetic Management of a Surgical Patient with Chronic Renal Tubular Acidosis Complicated by Subclinical Hypothyroidism by Hiroe Yoshioka, Haruyuki Yamazaki, Rie Yasumura, Kosuke Wada, Yoshiro Kobayashi

“…A 53-year-old man with chronic renal tubular acidosis and subclinical hypothyroidism underwent lower leg amputation surgery under general anesthesia. Perioperative acid-base management in such patients poses many difficulties because both pathophysiologies have the potential to complicate the interpretation of capnometry and arterial blood gas analysis data; inappropriate correction of chronic metabolic acidosis may lead to postoperative respiratory deterioration. …”
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