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Nanoparticle Therapy Is a Promising Approach in the Management and Prevention of Many Diseases: Does It Help in Curing Alzheimer Disease?
Published 2020-01-01“…Primary research studies in using nanoparticles to cure Alzheimer disease (AD) are promising but are still in need for more investigations. …”
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Neural mechanisms of non-pharmacological interventions in patients with mild cognitive impairment and Alzheimer's disease: An ALE meta-analysis
Published 2025-02-01Subjects: Get full text
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Preclinical Cognitive Markers of Alzheimer Disease and Early Diagnosis Using Virtual Reality and Artificial Intelligence: Literature Review
Published 2025-01-01“… Abstract BackgroundThis review explores the potential of virtual reality (VR) and artificial intelligence (AI) to identify preclinical cognitive markers of Alzheimer disease (AD). By synthesizing recent studies, it aims to advance early diagnostic methods to detect AD before significant symptoms occur. …”
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A Novel Mouse Model of Alzheimer's Disease with Chronic Estrogen Deficiency Leads to Glial Cell Activation and Hypertrophy
Published 2011-01-01“…The role of estrogens in Alzheimer's disease (AD) involving β-amyloid (Aβ) generation and plaque formation was mostly tested in ovariectomized mice with or without APP mutations. …”
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Identification of blood plasma protein ratios for distinguishing Alzheimer's disease from healthy controls using machine learning
Published 2025-02-01Subjects: “…Alzheimer's disease…”
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Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis
Published 2025-01-01“…Abstract: Background: Among neurodegenerative disorders Alzheimer's disease (AD) displays the highest prevalence and the projected increase in its incidence will require new advances in early diagnosis and treatment, particularly for distinguishing AD from other dementias. …”
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The inhibition of ORMDL3 prevents Alzheimer's disease through ferroptosis by PERK/ATF4/HSPA5 pathway
Published 2023-05-01Subjects: “…Alzheimer's disease…”
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The Precapillary Segment of the Blood-Brain Barrier and Its Relation to Perivascular Drainage in Alzheimer's Disease and Small Vessel Disease.
Published 2009-01-01“…Since the amyloid ß-protein (Aß) is subject of this perivascular drainage and accumulates in the brains of Alzheimer's disease (AD) patients, an alteration of this drainage system in the course of SVD may support the accumulation of Aß within the brain and, in so doing, the development of AD.…”
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DTI and MR Volumetry of Hippocampus-PC/PCC Circuit: In Search of Early Micro- and Macrostructural Signs of Alzheimers's Disease
Published 2012-01-01“…Hippocampal damage, by DTI or MR volumetry, and PET hypoperfusion of precuneus/posterior cingulate cortex (PC/PCC) were proposed as biomarkers of conversion from preclinical (MCI) to clinical stage of Alzheimer's disease (AD). This study evaluated structural damage, by DTI and MR volumetry, of hippocampi and tracts connecting hippocampus to PC/PCC (hipp-PC/PCC) in 10 AD, 10 MCI, and 18 healthy controls (CTRL). …”
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Investigating the neuroprotective effects of Dracocephalum moldavica extract and its effect on metabolomic profile of rat model of sporadic Alzheimer's disease
Published 2025-02-01Subjects: “…Sporadic Alzheimer's disease…”
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Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model
Published 2025-01-01Subjects: “…Alzheimer's disease…”
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Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease
Published 2025-01-01“…Abstract Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder with both genetic and environmental factors contributing to its pathogenesis. …”
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Nose to brain strategy coupled to nano vesicular system for natural products delivery: Focus on synaptic plasticity in Alzheimer's disease
Published 2024-12-01Subjects: “…Alzheimer's disease…”
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Neurotoxicity of aluminium chloride and okadaic acid in zebrafish: Unravelling Alzheimer's disease model via learning and memory function evaluation
Published 2025-01-01“…Introduction/objectives: Alzheimer's disease (AD) is characterised by a progressive decline in cognitive abilities, especially learning and memory. …”
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APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease
Published 2025-01-01Subjects: Get full text
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A Middle-Aged Woman with Logopenic Progressive Aphasia as a Precursor of Alzheimer's Disease: Case Report and Review of the Literature
Published 2011-01-01“…The logopenic variant is the least common one and is closely related to Alzheimer's disease in comparison to the other two variants that are closely related to frontotemporal dementia. …”
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Reply to “Concerns about methodology and findings in coffee and tea consumption and dementia research”
Published 2025-02-01Subjects: “…Alzheimer's disease…”
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Coffee and tea consumption and dementia risk: The role of sex and vascular comorbidities
Published 2025-02-01Subjects: “…Alzheimer's disease…”
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Reply to “Coffee and tea consumption and dementia risk: The role of sex and vascular comorbidities”
Published 2025-02-01Subjects: “…Alzheimer's disease…”
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