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Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease
Published 2025-02-01“…Background: Alzheimer's disease (AD) is a heterogeneous and progressive neurodegenerative disorder characterized by cognitive impairment and behavioral disturbances. …”
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Navigating the Role and Approach of Gut Microbiota in Addressing Alzheimer's Disease Pathogenesis
Published 2024-11-01Get full text
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Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease.
Published 2025-01-01“…Numerous studies of the human brain supported by experimental results from rodent and cell models point to a central role for intracellular amyloid beta (Aβ) in the onset of Alzheimer's disease (AD). In a rat model used to study AD, it was recently shown that in layer II neurons of the anteriolateral entorhinal cortex expressing high levels of the glycoprotein reelin (Re+alECLII neurons), reelin and Aβ engage in a direct protein-protein interaction. …”
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Alzheimer's disease image classification based on enhanced residual attention network.
Published 2025-01-01“…With the increasing number of patients with Alzheimer's Disease (AD), the demand for early diagnosis and intervention is becoming increasingly urgent. …”
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PROTEOMIC PROFILING OF BLOOD-BASED BIOMARKERS IN THE EARLY DETECTION OF ALZHEIMERS DISEASE
Published 2024-06-01“…AD is remarkable for the presence of a large number of cognitive deficiencies which results in notable impairment of social and occupational function. Alzheimer's disease has now become one of the most problematic and expensive health issues for society. …”
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Developing non-invasive molecular markers for early risk assessment of Alzheimer's disease
Published 2025-06-01“…Alzheimer's disease (AD) is a heterogeneous neurodegenerative disease, with no standard biomarker(s) to detect or confirm its risk at an early stage. …”
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Expanding perspectives on the relationship between statin potency and lipophilicity in Alzheimer's disease management
Published 2025-02-01Subjects: Get full text
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Brain targeting based nanocarriers loaded with resveratrol in Alzheimer's disease: A review
Published 2023-05-01“…Abstract Alzheimer's disease (AD) is one of the chief neurological difficulties in the aged population, identified through dementia, memory disturbance, and reduced cognitive abilities. β‐amyloid (Aβ) plaques aggregations, generation of reactive oxygen species, and mitochondrial dysfunction are among the major signs of AD. …”
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Exploring the effects of combined nostalgic activities and music therapy on Alzheimer's disease outcomes
Published 2025-01-01Subjects: “…Alzheimer's disease…”
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Characterization of gene expression profiles in Alzheimer's disease and osteoarthritis: A bioinformatics study.
Published 2025-01-01“…<h4>Background</h4>Alzheimer's disease (AD) and Osteoarthritis (OA) have been shown to have a close association in previous studies, but the pathogenesis of both diseases are unclear. …”
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Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer's Disease
Published 2012-01-01“…The natural isoquinoline alkaloid berberine possesses potential to treat Alzheimer's disease (AD) by targeting multiple pathogenic factors. …”
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Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances
Published 2025-02-01Subjects: “…Alzheimer's disease…”
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Cerebrospinal Fluid BACE1 Activity and Brain Amyloid Load in Alzheimer's Disease
Published 2012-01-01“…The secretase BACE1 is fundamentally involved in the development of cerebral amyloid pathology in Alzheimer's disease (AD). It has not been studied so far to what extent BACE1 activity in cerebrospinal fluid (CSF) mirrors in vivo amyloid load in AD. …”
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Coffee and tea are unlikely to be risk factors or preventers of Alzheimer's disease or vascular dementia
Published 2025-02-01Subjects: Get full text
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Neurogranin in Alzheimer's Disease: Roles in synaptic function, pathology, and potential as a diagnostic biomarker
Published 2024-09-01Subjects: Get full text
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Polyunsaturated Fatty Acid and S-Adenosylmethionine Supplementation in Predementia Syndromes and Alzheimer's Disease: A Review
Published 2009-01-01“…In this review article, we focus on dietary supplementation suggested for predementia syndromes and Alzheimers disease (AD), with particular emphasis on S-adenosylmethionine (SAM) and polyunsaturated fatty acids (PUFA). …”
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The use of virtual reality in screening for preclinical Alzheimer's disease: A scoping review protocol.
Published 2023-01-01“…<h4>Introduction</h4>Preclinical Alzheimer's disease (AD) represents the earliest phase of AD, often years before the onset of mild cognitive impairment (MCI). …”
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Zinc Metalloproteinases and Amyloid Beta-Peptide Metabolism: The Positive Side of Proteolysis in Alzheimer's Disease
Published 2011-01-01“…Alzheimer's disease is a neurodegenerative condition characterized by an accumulation of toxic amyloid beta- (A𝛽-)peptides in the brain causing progressive neuronal death. …”
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Detection of Alzheimer Disease in Neuroimages Using Vision Transformers: Systematic Review and Meta-Analysis
Published 2025-02-01“… BackgroundAlzheimer disease (AD) is a progressive condition characterized by cognitive decline and memory loss. …”
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Moroccan natural products for multitarget-based treatment of Alzheimer's disease: A computational study.
Published 2025-01-01“…Alzheimer's disease is a neurodegenerative disorder that impairs neurocognitive functions. …”
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