Integration of Umbilical Cord Mesenchymal Stem Cell Application in Hydroxyapatite-Based Scaffolds in the Treatment of Vertebral Bone Defect due to Spondylitis Tuberculosis: A Trans... by Ahmad Jabir Rahyussalim, Ahmad Nugroho, Muhammad Luqman Labib Zufar, Irfan Fathurrahman, Tri Kurniawati

“…Results. The initial mean ALP level at one-month follow-up was 48.33±8.50 U/L. …”
Get full text

Determinants of mortality and prolonged hospital stay among dengue patients attending tertiary care hospital: a cross-sectional retrospective analysis by Yusra Habib Khan, Tauqeer Hussain Mallhi, Amer Hayat Khan, Azmi Sarriff, Azreen Syazril Adnan

“…Multivariate analysis showed that dengue haemorrhagic fever (OR 2.3), elevated alkaline phosphatase (ALP) (OR 2.3), prolonged prothrombin time (PT) (OR 1.7), activated partial thromboplastin time (aPTT) (OR 1.9) and multiple-organ dysfunctions (OR 2.1) were independently associated with prolonged hospitalisation. …”
Get full text

Integrating wide-swath altimetry data into Level-4 multi-mission maps by M. Ballarotta, C. Ubelmann, V. Bellemin-Laponnaz, F. Le Guillou, G. Meda, C. Anadon, A. Laloue, A. Delepoulle, Y. Faugère, M.-I. Pujol, R. Fablet, G. Dibarboure

Get full text

A multi‐tagged SAR ocean image dataset identifying atmospheric boundary layer structure in winter tradewind conditions by Chen Wang, Justin E. Stopa, Doug Vandemark, Ralph Foster, Alex Ayet, Alexis Mouche, Bertrand Chapron, Peter Sadowski

Get full text

Using Large Language Models to Detect and Understand Drug Discontinuation Events in Web-Based Forums: Development and Validation Study by William Trevena, Xiang Zhong, Michelle Alvarado, Alexander Semenov, Alp Oktay, Devin Devlin, Aarya Yogesh Gohil, Sai Harsha Chittimouju

Get full text

Short bouts and long-term exercise reduce sedentary-induced bone loss and microstructural changes by modulating bone formation and resorption in healthy young male rats by L.Y. Wang, L.M. Liang, X.X. Zhang, H. Chi, F. L. Peng

“…Meanwhile, we found that, at 4 and 8 weeks, there was an increase in serum ALP. At 8 weeks, the mineralized nodules surface with Alizarin Red S-staining, and OPG mRNA and proteins level in bone tissue were significantly increased. …”
Get full text

The Clinical Pharmacokinetics and Pharmacodynamics of Glimepiride—A Systematic Review and Meta-Analysis by Mubara Azhar, Mohammed S. Alasmari, Ammara Zamir, Hamid Saeed, Faleh Alqahtani, Tanveer Ahmad, Muhammad Fawad Rasool

Get full text

The antiosteoporotic effect of oxymatrine compared to testosterone in orchiectomized rats by Anwaar M. Shaban, Eman A. Ali, Sara G. Tayel, Sara Kamal Rizk, Dalia F. El Agamy

“…Urinary deoxypyridinoline (DPD), calcium (Ca), and phosphorus (P), as well as serum testosterone, parathormone (PTH), alkaline phosphatase (ALP), osteocalcin, N-telopeptide of type I collagen (NTX I), tartrate resistance acid phosphatase (TRAP), and total Ca and P levels were evaluated. …”
Get full text

Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model by Jian Ding, Jian Ding, Zheng Long, Yiming Liu, Min Wang

“…LASSO regression identified the following 11 features closely related to aCCI: age, respiratory rate, base excess, glucose, red blood cell distribution width (RDW), alkaline phosphatase (ALP), whole blood potassium, hematocrit (HCT), phosphate, creatinine, and mean corpuscular hemoglobin (MCH). …”
Get full text

Preparation and In Vivo Expression of CS-PEI/pCGRP Complex for Promoting Fracture Healing by Chun-Liang Li, Feng Qin, Rong-rong Li, Jia Zhuan, Hai-Yong Zhu, Yu Wang, Kai Wang

“…Moreover, CS-PEI/pCGRP significantly enhanced the mRNA and protein levels of downstream RUNX2 and ALP. Conclusion. CS-PEI/pCGRP nanoparticles were an effective nonviral gene transfection system that could upregulate CGRP expression in vivo and accelerate the expression of key biomarkers for early healing of fractures.…”
Get full text

Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with brucellosis resistance/susceptibility in Shami goat by Ahmed A. Elsayed, Ahmed M. Sallam

“…The results of serum profile indicated that there is a significant (P < 0.05) increase in the activities of AST, ALT, GGT, LDH, ALP as well as serum level of globulin, triglycerides, cholesterol, MDA, NO, IL-1β, TNF-α, IgM, IgG, haptoglobin and amyloid A. …”
Get full text

Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme by Petit, Benoît Eric, Jobelius, Hannah, Bianchino, Gabriella Ines, Guérin, Mélina, Borel, Franck, Chaignon, Philippe, Seemann, Myriam

Get full text

Microplastics in freshwaters: Comparing effects of particle properties and an invertebrate consumer on microbial communities and ecosystem functions by Ze Hui Kong, Tong Liu, Francis J. Burdon, Amélie Truchy, Martyn Futter, Mirco Bundschuh, Rachel Hurley, Stefan Bertilsson, Brendan G. Mckie

Get full text

Gene expression in gastric biopsies from patients with Helicobacter pylori infection by D. Davoudi Oskouei, H. Akpınar, S. Sarıoğlu, P. Keskinoğlu, M. Soytürk, İ. Şimşek, Ö. Yılmaz

“…We investigated the expression of H. pylori cagA, omp6 (hopA), omp13 (oipA), omp18, and omp20 (alpA) genes and their associations with clinicopathological findings. …”
Get full text

Efficacy of the Bushen Jianpi Huoxue Formula on Beclin-1/Bcl-2-mediated autophagy and apoptosis in osteoblasts by Yanping Lin, Yanping Lin, Rui Zhao, Rui Zhao, Jiachun Huang, Tongying Chen, Tongying Chen, Haolin Yang, Haolin Yang, Haiwei Guo, Lei Wan, Zhihai Zhang, Ying Li, Genfu Zhu, Hongxing Huang, Hongxing Huang

“…Osteogenic differentiation was assayed by ALP staining, and mineralization by ARS staining. …”
Get full text

Analysis of the Effect of Human Type I Collagen-Derived Peptide on Bone Regenerative Capacity and Comparison with Various Collagen Materials In Vivo by Tatsunori Asakura, Tran Thi Thuy Diep, Yuta Ueda, Aoi Yamada, Takahiro Tsuzuno, Naoki Takahashi, Masayuki Miyata, Koichi Tabeta, Masaki Nagata, Ken Matsuda

“…Gene expression analysis demonstrated that Cellnest significantly increased the levels of the bone formation markers ALP and COL1. <i>Conclusions</i>: Cellnest, a human type I collagen-like peptide rich in RGD motifs, enhances bone regeneration by promoting MSC adhesion and migration, and bone formation-related gene expression. …”
Get full text

Effects of dietary bile acid on the growth performance, intestinal health, blood biochemistry, and antioxidative response of Nile tilapia (Oreochromus niloticus) fed high-fat diets by Mahmoud A.O. Dawood, Sameh El-Dahan, Samy Elsaadawy, Ahmed E. Noreldin, Hani Sewilam

“…Fish-fed HF diet also showed increased total cholesterol, triglycerides, glucose, ALP, and AST levels as well as the malondialdehyde level (MDA). …”
Get full text

miR-129-5p Promotes Osteogenic Differentiation of BMSCs and Bone Regeneration via Repressing Dkk3 by Changming Zhao, Yulin Gu, Yan Wang, Qiaozhen Qin, Ting Wang, Meng Huang, Heyang Zhang, Yannv Qu, Jingwen Zhang, Zhangzhen Du, Xiao-Xia Jiang, Lulu Xu

“…The ability of BMSC differentiation to osteoblast was tested by alkaline phosphatase (ALP) and alizarin red staining (ARS). The expression of osteogenic genes (Runx2, Bmp2, and OCN) was examined via quantitative RT-PCR and western blot. …”
Get full text

Green magnetically separable molluscicide Ba–Ce–Cu ferrite/TiO2 nanocomposite for controlling terrestrial gastropods Monacha Cartusiana by Abdullah A. Alamri, Mohamed A. Ayyad, Hossameldin G. Mohamedbakr, Usama A. Soliman, Majed Y. Almashnowi, Jia Hong Pan, Elsayed T. Helmy

“…Analysis of biochemical variables as a bio response indicator showed a noticeable increase in the values of aspartate transaminase (AST) and alanine transaminase (ALT) relative to the control, while the decrease was characteristic for alkaline phosphatase (ALP) and total protein (TP) other variables when the animals were treated with LC50 value. …”
Get full text

Parámetros de laboratorio clínico en pacientes con la COVID-19 by Naivy Sánchez Vera, Danay Saavedra Hernández, Carlos Jorge Hidalgo Mesa, Maykel Aguila López, Gladys Abreu Gutiérrez, Vivian Herrera González, Iliana Teresa Rodríguez García

“…Disminuyen los valores medios de hemoglobina, conteo global de los linfocitos, sobre todo en graves; aumenta el dímero D, creatinina, ALT, AST, ALP, GGT, y LD. La relación neutrófilos/ linfocitos y de plaquetas/ linfocitos muestran valores medios altos, sobre todo en graves y en quienes fallecieron. …”
Get full text