Ascension du mont Blanc (4808 m) : quels risques prend-on dans le Grand Couloir du Goûter et dans la face nord du mont Blanc du Tacul ? by Ludovic Ravanel, Jacques Mourey, Lorig Tamian, Sébastien Ibanez, Didier Hantz, Pascal Lacroix, Pierre-Allain Duvillard

“…Les alpinistes doivent ainsi faire face à des aléas glaciaires et périglaciaires importants, tels que ceux qui affectent les deux principaux itinéraires d’ascension du mont Blanc (4808 m ; Alpes européennes occidentales) : les chutes de pierres dans le Grand Couloir de l’aiguille du Goûter sur la Voie Royale et les chutes de séracs sur le versant NNO du mont Blanc du Tacul sur l’itinéraire des Trois Monts. …”
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Nomogram for prognosis prediction in metastatic pancreatic cancer patients undergoing intra-arterial infusion chemotherapy: incorporating immune-inflammation scores and coagulation... by Yifan Yang, Shaoqi Zong, Yongqiang Hua

“…Through Cox regression analysis, a nomogram was ultimately constructed incorporating NLR, PLR, PT, alkaline phosphatase (ALP), carbohydrate antigen 125 (CA125), age, and ablation. …”
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Dynamic recrystallization and mechanical behavior of Mg alloy AZ31: Constraints from tensile tests with in-situ EBSD analysis by Boissonneau, Gaëtan, Tommasi, Andréa, Barou, Fabrice, Lopez-Sanchez, Marco Antonio, Montagnat, Maurine

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La gestion paradoxale des ripisylves des cours d’eau de piedmont alpin endigués by André Evette, Caroline Zanetti, Paul Cavaillé, Fanny Dommanget, Patrice Mériaux, Michel Vennetier

“…Des expérimentations menées dans le cadre du Projet Interreg Géni’Alp en piedmont alpin ont permis d’affiner les connaissances à la fois sur les risques induits par les systèmes racinaires des ligneux dans les digues et sur l’impact de l’artificialisation des bords de cours d’eau sur la biodiversité.Cet article a pour objectif d’illustrer ce paradoxe à la lueur des résultats de ces expérimentations. …”
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Fieldwork on animals living in extreme conditions as a source of biomedical innovation by Yvon Le Maho, Aurélie Tasiemski, Fabrice Bertile, Philippe Bulet

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Early outcomes of treatment selections for infrarenal abdominal aortic aneurysms: The first five year experience of a single center by Bahadir Aytekin, Goktan Askin, Naim Boran Tumer, Hayrettin Levent Mavioglu, Seref Alp Kucuker, Ahmet Saritas, Hakki Zafer Iscan, Mehmet Ali Ozatik, Erol Sener

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Le rôle des limites locales dans la sobriété énergétique : éclairages à partir du cas de l’autoconsommation collective en France by Jessica Zaphiropoulo

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The Use of Trichostatin A during Pluripotent Stem Cell Generation Does Not Affect MHC Expression Level by Sara Farahi, Sara Hosseini, Hossein Ghanbarian, Seyed Mahmoud Hashemi, Mohammad Salehi, Samaneh Hosseini

“…Established PSC lines were characterized by alkaline phosphatase assay (ALP) and immunocytochemistry. Their chromosome fidelity was checked by karyotyping. …”
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Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways by Md. Niaj Morshed, Reshmi Akter, Imran Mahmud, Ah-Yeong Gwon, Jin Woo Jeang, Yeong-Geun Lee, Dae Won Park, Deok Chun Yang, Yeon Ju Kim, Se-Chan Kang

“…Additionally, CK treatment induced osteoblast development in MC3T3-E1 cells as shown by increased mineralization and calcium distribution, collagen content, alkaline phosphatase activity, and decreased inflammatory cytokines <i>TNFα</i>, and <i>IL-6</i> and increased the regulated expressions of osteogenic genes including <i>Runx2</i>, <i>ALP</i>, <i>BGLAP</i>, <i>OCN</i>, and <i>Col1a1</i>. …”
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Complement Receptors C5aR and C5L2 Are Associated with Metabolic Profile, Sex Hormones, and Liver Enzymes in Obese Women Pre- and Postbariatric Surgery by Reza Rezvani, Jessica Smith, Marc Lapointe, Picard Marceau, Andre Tchernof, Katherine Cianflone

“…Over 12 months postoperatively, liver enzymes in low C5L2/C5aR mRNA ratio group remained higher (ALP and ALT, P<0.05, AST and GGT, P<0.001 2-way-ANOVA). …”
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Toxicological Effects of Commonly Used Mosquito Coil Smoke on Liver and Lung Function in Rats by Hadiza Abubakar, Yahuza Gimba Muhammed, Alhassan Muhammad Wudil, Dayyabu Shehu, Murtala Yaú

“…Following the exposure periods, blood samples were collected for the analysis of serum-based and biochemical markers, including serum aspartate aminotransferase (AST), alanine aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), bilirubin, serum bicarbonate, and Lactate dehydrogenase (LDH), oxygen saturation, C-reactive protein, total protein, and microscopic analysis of lung tissue and liver tissue. …”
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HCV and HBV genotypes: vital in the progression of HCV/ HBV co-infection by Yasmin Badshah, Maria Shabbir, Khushbukhat Khan, Sameen Zafar, Tayyaba Afsar, Fohad Mabood Husain, Houda Amor, Suhail Razak

“…To determine the liver damage due to viral infection levels of ALT, ALP, and total bilirubin were also determined. Diagnostic history of patients was thoroughly documented through serological tests and liver biopsy reports. …”
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Hypermethylation in Calca Promoter Inhibited ASC Osteogenic Differentiation in Rats with Type 2 Diabetic Mellitus by Lei Wang, Feng Ding, Shaojie Shi, Xingxing Wang, Sijia Zhang, Yingliang Song

“…Meanwhile, it could significantly enhance the formation of ALP and calcium nodules in ASCs-T2DM, increase the expression of osteogenesis-related genes in vitro, and promote the healing of calvarial defects of T2DM rat in a concentration-dependent manner. 5-az intervention indicated that the reduction of the methylation level in Calca target fragment of ASCs-T2DM indeed escalated the gene expression, which may be related to DNMT1. …”
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Cytoreductive Nephrectomy and Nephrectomy/Complete Metastasectomy for Metastatic Renal Cancer by Paul Russo, Mark Synder, Andrew Vickers, Varuni Kondagunta, Robert Motzer

“…Preoperative laboratory values analyzed included hemoglobin (HGB), calcium (CA), albumin (ALB), lactose dehydrogenase (LDH), alkaline phosphatase (ALP), and corrected calcium. Corrected calcium was defined as follows: corrected calcium = total calcium - 0.707*(albumin - 3.4). …”
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Tryptophan and/or canthaxanthin in quail diets: effects on performance, carcass traits, hematology, blood chemistry and hepatic antioxidant capacity by Khaled H. El-Kholy, Mohamed E. Sokariaa, Mohammed F. El Basuini, Sara F. Fouda, Tarek A. Ebeid, Ibrahim T. El-Ratel, Mahmoud M. Azzam, Alessandro Di Cerbo, Ahmed A. Elolimy, Mahmoud Madkour, Mahmoud Alagawany

“…Adding Trp and/orCX to quail diets significantly (P < 0.05) decreased the activity of liver enzymes (alanine transaminase, ALT; aspartate transaminase, AST; alkaline phosphatase, ALP), along with reduced low-density lipoprotein (LDL) levels. …”
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A phase II double-blind multicentre, placebo-controlled trial to assess the efficacy and safety of alpelisib (BYL719) in paediatric and adult patients with Megalencephaly-CApillary... by Jean-Marc Treluyer, Benedicte Demeer, Laurence Faivre, Marc Bardou, Nathalie Boddaert, Paul Kuentz, Florence Petit, Christine Francannet, Pierre Vabres, Nadia Bahi-Buisson, Estelle Colin, Laurent Guibaud, Romaric Loffroy, Maxime Luu, Caroline Racine, Aurore Garde, Philippe Khau Van Kien, Aurore Curie, Nawale Hadouiri, Aurélie Espitalier, Agnès Maurer, Maud Carpentier, Adélaide Rega, Mouna Chebbi, Julie Charligny, Guillaume Canaud, Camille Fleck, Amelie Cransac, Elise Boucher-Brischoux, Adélaïde Brosseau-Beauvir, Florian Cherik, Alice Phan, Michaela Semeraro, Marion Nys, Charles Joris Roux, Alinoë Lavillaureix, Isabelle Maruani

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2,4-Dichlorophenoxyacetic Acid in the Gas and Crystal Phases and Its Intercalation in Montmorillonite—An Experimental and Theoretical Study by Claro Ignacio Sainz-Díaz, Nelly L. Jorge, Jorge M. Romero, André Grand, Alfonso Hernández-Laguna

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Forecasting Geomagnetic Storm Disturbances and Their Uncertainties Using Deep Learning by D. Conde, F. L. Castillo, C. Escobar, C. García, J. E. García, V. Sanz, B. Zaldívar, J. J. Curto, S. Marsal, J. M. Torta

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Geomorphic imprint of high-mountain floods: insights from the 2022 hydrological extreme across the upper Indus River catchment in the northwestern Himalayas by A. Kashyap, K. L. Cook, M. D. Behera

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Effects of Titanium Dioxide Nanoparticles on Chick Embryo: Immunomodulatory, Hepatic and Biochemical Alterations by Md. Sadequl Islam, Md. Nurul Amin, Mst. Deloara Begum

“…Results The results revealed subcutaneous haemorrhage, significant reductions in total body weight and marked changes in biochemical markers, including urea, creatinine, alkaline phosphatase (ALP), aspartate aminotransferase (AST) and alanine aminotransferase (ALT), in the amniotic fluid of the groups treated with TiO2 NPs, compared to the control. …”
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