ET-1 Promotes Differentiation of Periodontal Ligament Stem Cells into Osteoblasts through ETR, MAPK, and Wnt/β-Catenin Signaling Pathways under Inflammatory Microenvironment by Li Liang, Wei Zhou, Nan Yang, Jifeng Yu, Hongchen Liu

“…The osteogenic potential of PDLSCs was tested using ALP staining. TNF-α, IL-1β, and IL-6 levels were evaluated by ELISA and western blot. …”
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Competitive and collaborative relationship between Al–3P and TiB2 nanoparticles in the microstructure manipulation of eutectic Al–Si alloys by Yi-Lu Li, Bai-Xin Dong, Hong-Yu Yang, Dan Luo, Shi-Li Shu, Zhi-Fa Wang, Jie Kang, Jia Meng, Chang-Jie Luo, Cheng-Gang Wang, Kuang Cao, Jian Qiao, Ming Zhu, Feng Qiu, Qi-Chuan Jiang

“…In this work, the synergistic effects of the modifier Al–3P master alloy and nano-TiB2 ceramic particles on the microstructure and mechanical performance of cast eutectic Al–Si alloys were investigated. Results showed that AlP and nano-TiB2 particles served as efficient heterogeneous nucleation sites of Si and α-Al, respectively. …”
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Kadukkai maathirai (Indian herbal drug) prevents hepatocellular cancer progression by enhancing GSTM1 expression and modulating β catenin transcription: in-silico and in-vivo study... by Akshatha Shetty, Shama Prasada K, Diya Rajasekhar Chinta, Ganesh Shenoy, Amruth Kiran, Vasudha Devi, Arul Amuthan, Smita Shenoy, Manjunath Shetty, Mohandas Rao K G, Nitesh Kumar

“…Hepatoprotective potential (serum AST, ALT, ALP, Bilirubin) and anticancer efficacy (body weight, nodule count, tumor progression by histopathology, expression of GSTM1 by Liquid chromatography-mass spectrometry (LC-MS), and In-silico analysis of phytoconstituents against β catenin and LRP analysis were evaluated. …”
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The effect of local propolis irrigation as an adjunct to scaling and root planning on alveolar bone loss in experimental periodontitis in rats (A biochemical and histological stu... by Khadeeja Mohammed Ali, Zewar Ahmad Saleh, Jalal Ali Jalal

“…Results: Rats that received local treatment by SRP with propolis irrigation in gp3 revealed features of acceleration of the periodontal tissue-repair process, alveolar bone formation, and significantly higher alkaline phosphatase serum levels (ALP) than gp2 were treated by SRP with vehicle irrigation. …”
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MEK1/2 Inhibitor (GDC0623) Promotes Osteogenic Differentiation of Primary Osteoblasts Inhibited by IL-1β through the MEK-Erk1/2 and Jak/Stat3 Pathways by Zeng-Qiao Zhang, Xiao-Shen Hu, Ye-Chen Lu, Jun-Peng Zhang, Wen-Yao Li, Wei-Yang Zhang, Wei Feng, Dao-Fang Ding, Jian-Guang Xu

“…Osteoblasts were cultured in an osteogenic induction medium for 1–3 weeks after which their differentiations were assessed by alkaline phosphatase (ALP) staining, Alizarin Red staining, calcium concentration, immunocytochemistry staining, real-time quantitative PCR (RT-qPCR), and immunofluorescence staining. …”
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Histological, physiological and transcriptomic analysis in hepatopancreas of Procambarus clarkii under heat stress by Yongfeng Zou, Panhui Cao, Zhiming Bao, Yu Xu, Zhiqiang Xu, Hui Guo

“…Significant fluctuations were observed in the malondialdehyde (MDA) content, reactive oxygen species (ROS) production, total antioxidant capacity (T-AOC), and activities of pyruvate kinase (PK), hexokinase (HK), alkaline phosphatase (ALP), lysozyme (LYS), acid phosphatase (ACP), fatty acid synthase (FAS), as well as lipoprotein lipase (LPL) in response to different stress conditions (P < 0.05). …”
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Semaphorin3B Promotes Proliferation and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in a High-Glucose Microenvironment by Quan Xing, Jingyi Feng, Xiaolei Zhang

“…Furthermore, HG inhibited osteogenic differentiation in BMSCs by decreasing the expression of bone formation markers, alkaline phosphatase (ALP) activity, and mineralization. However, the administration of recombinant Sema3B reversed all of these effects. …”
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Perfluorooctane sulfonate (PFOS) induced bone loss by inhibiting FoxO1-mediated defense against oxidative stress in osteoblast by Liming Xue, Jiale Xu, Ping Xiao, Yiping Jiang, Yuanjie Lin, Chao Feng, Yu’e Jin, Zhijun Zhou, Guoquan Wang, Dasheng Lu

“…Our research is aimed at examining the effects of PFOS on osteoblastic activity and investigating the toxicological mechanisms of PFOS-induced bone loss. Cell proliferation, ALP activity, bone nodule formation, ROS levels, and cell apoptosis were assessed after treating osteoblasts with different concentrations of PFOS. …”
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Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects by Tianlin Liu, Xin Zhang, Yuan Luo, Yuanliang Huang, Gang Wu

“…In in vitro cellular experiments, icariin at optimal concentration (10−6 mol/L) could significantly upregulate the osteogenesis- and angiogenesis-related genes and proteins, such as Runx2, ALP, osteocalcin, vascular endothelial growth factors, and fibroblast growth factors, as well as the mineralization of BMSCs. …”
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Automatic approach-avoidance tendency toward physical activity, sedentary, and neutral stimuli as a function of age, explicit affective attitude, and intention to be active by Farajzadeh, Ata, Goubran, Miriam, Beehler, Alexa, Cherkaoui, Noura, Morrison, Paula, de Chanaleilles, Margaux, Maltagliati, Silvio, Cheval, Boris, Miller, Matthew W., Sheehy, Lisa, Bilodeau, Martin, Orsholits, Dan, Boisgontier, Matthieu P.

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A meta-analysis of epigenome-wide association studies of ultra-processed food consumption with DNA methylation in European children by Joana Llauradó-Pont, Nikos Stratakis, Giovanni Fiorito, Evangelos Handakas, Alexander Neumann, Henrique Barros, Anne Lise Brantsæter, Kiara Chang, Leda Chatzi, Janine F. Felix, Regina Grazuleviciene, Vincent W. V. Jaddoe, Marianna Karachaliou, Marion Lecorguillé, Carla Lopes, Christopher Millett, Rosemary R. C. McEachan, Eleni Papadopoulou, Remy Slama, Eszter P. Vamos, Paolo Vineis, Martine Vrijheid, John Wright, Trudy Voortman, Mariona Bustamante, Oliver Robinson, Camille Lassale

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Pancreatic Metastasis of High-Grade Papillary Serous Ovarian Carcinoma Mimicking Primary Pancreas Cancer: A Case Report by Yusuf Gunay, Ebru Demiralay, Alp Demirag

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Amniotic Fluid β2- Microglobulin Measurements by Emine Aydın, Alp Tuna Beksaç, Ergün Karaağaoğlu, M. Sinan Beksaç

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Marginalité, adaptation et agriculture dans les hautes terres de Nouvelle-Zélande by Steven Kelly, Willie Smith

“…Soumis aux séismes (principalement dans les Alpes du Sud) et aux éruptions volcaniques (sur le plateau central de l’Île du Nord), les espaces montagnards de Nouvelle-Zélande sont plus généralement enclins à des problèmes d’érosion et de glissements de terrain, et à des chutes de neiges aussi extrêmes qu’irrégulières, dans le Sud. …”
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Lipemia Interferences in Biochemical Tests, Investigating the Efficacy of Different Removal Methods in comparison with Ultracentrifugation as the Gold Standard by Neda Soleimani, Sahand Mohammadzadeh, Fateme Asadian

“…According to our study, there were significant differences before and after ultracentrifugation in all lipemic levels and for all parameters except for alanine aminotransferase (ALT), alkaline phosphatase (ALP), bilirubin, and uric acid. Based on allowable inaccuracy for each parameter, calcium, magnesium, phosphorus, total protein, iron, total iron-binding capacity (TIBC), urea, and chloride are being influenced by all lipemic degree and neither serum dilution nor using serum blank is as effective as ultracentrifuge for elimination. …”
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Emergent spinal pathologies in late-term pregnancy by Souvik Roy, Rida Mitha, Raj Swaroop Lavadi, Rohit Prem Kumar, Vinay Jaikumar, Matthew Pease, Nima Alan, Alp Ozpinar, Eren Kuris, Alan H. Daniels, Thomas J. Buell, Robert F. Heary, Nitin Agarwal, D. Kojo Hamilton

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Improving the Push-Out Bond Strength of Fiber Posts in Diabetic Dentin: The Role of Chlorexidine Irrigation and Resin Cements by Beyza Arslandaş Dinçtürk, Arzu Şahin Mantı, Cemile Kedici Alp, Ayşenur Altuğ Yıldırım, Arzu Kaya Mumcu

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A Study of Physical Fitness and Enjoyment on Virtual Running for Exergames by Chaowanan Khundam, Frédéric Nöel

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Statin Induced Changes in Rat Pancreatic Tissue: A Histological and Biochemical Perspective by Abdullah Qamar, Hammad Gul Khan, Muhammad Marghoob Khan, Muhammad Rizwan Bashir Kiani, Hina Kundi, Fareeha Mushtaq

“…Specifically, there was a significant reduction in serum amylase levels and a concomitant increase in serum alkaline phosphatase (ALP) levels, as compared to the control group. …”
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The zoning of the relative morphotectonic activity of the Kan-Soleghan basin with an emphasis on the location of the Tehran-North Freeway tunnel by sara Kiani, Amir Karam, Nasrin Hoseinaei

“…The Kan-Soleghan basin is located on the southern Hillside of the Alborz, which has affected the Alp-Himalayan active zone over time. In this respect, the evaluation of active tectonic processes and their effects on many human activities, such as the design and construction of cities, powerhouse, dams, and industrial facilities are of great importance. …”
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