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  1. 521

    Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo by Soyeon Hong, Hee Ju Lee, Da Seul Jung, Saruul Erdenebileg, Hoseong Hwang, Hak Cheol Kwon, Jaeyoung Kwon, Gyhye Yoo

    Published 2025-01-01
    “…Methods and Results: The alkaline phosphatase (ALP) activity of <i>C. wilsonii</i> extracts and fractions was evaluated in MC3T3-E1 pre-osteoblasts, and the <i>n</i>-hexane fraction (CWH) showed the best properties for ALP activity. …”
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  2. 522
  3. 523

    The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow by Sirikul Manochantr, Kulisara Marupanthorn, Chairat Tantrawatpan, Pakpoom Kheolamai, Duangrat Tantikanlayaporn, Prakasit Sanguanjit

    Published 2017-01-01
    “…The osteogenic differentiation capacity after miRNA treatment was assessed by ALP expression, ALP activity, and osteogenic marker gene expression. …”
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  4. 524

    Combination of geographical and socio-economic proximities by Eric Boutroy, Philippe Bourdeau, Pascal Mao, Nicolas Senil

    Published 2013-03-01
    “…Such observations do not imply the absence, in Rhône-Alpes, of strong interaction between geographically close actors, but rather prompt a more descriptive and measured approach in addressing the phenomenon. …”
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  5. 525

    Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

    Published 2025-02-01
    “…Alkaline phosphatase (ALP) is a ubiquitously expressed dephosphorylating enzyme and its level in blood is widely used as a diagnosis marker of liver damage or bone disorders in human patients. …”
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  6. 526
  7. 527

    The role of vitamin D in slipped capital femoral epiphysis in children and adolescents: a retrospective case-control study by Peng Ning, Shuting Lin, Huiyu Geng, Tianjing Liu

    Published 2025-01-01
    “…Significant differences were found in 25(OH)D, ALP, free thyroxine (FT4), and Mg (P&lt;0.05). The SCFE group had lower 25(OH)D and ALP levels but higher FT4 and Mg. …”
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  8. 528

    Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch by Shiyong Ling, Xi Luo, Bo Lv, Hua Wang, Mengzhi Xie, Kai Huang, Jingchuan Sun

    Published 2022-01-01
    “…Compared with the MSC group, the level of miR-144-3p was significantly lower and the level of PTEN was significantly higher in the tension MSC group. ALP staining showed normal activity in the MSC group and decreased ALP activity in the tension MSC group compared to the MSC group. …”
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    Article
  9. 529

    Humoral and Cellular Immune Regulation in Albino Rat Exposed to Glyphosate and Aluminum Phosphide by Ujuamala Ezeani, Onyemaechi Afonne, Michael Ezeani

    Published 2024-12-01
    “…Background: Glyphosate (GLP) and Aluminum phosphide (ALP) pesticides remain vital for managing pests and disease vectors in both agriculture and public health. …”
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  11. 531

    Inhibiting Autophagy by Chemicals During SCAPs Osteodifferentiation Elicits Disorganized Mineralization, While the Knock-Out of <i>Atg5/7</i> Genes Leads to Cell Adaptation by Damien Le Nihouannen, Claudine Boiziau, Sylvie Rey, Nicole Agadzhanian, Nathalie Dusserre, Fabrice Cordelières, Muriel Priault, Helene Boeuf

    Published 2025-01-01
    “…We showed that blocking the formation of autophagosomes with verteporfin did not induce a dramatic alteration in early osteoblastic differentiation monitored by ALP (alkaline phosphatase) activity. However, blocking the autophagy flux with bafilomycin A1 led to ALP repression. …”
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  12. 532

    The effect of silver nitrate on the alkaline phosphatase activity, TNF and IL-10 gene expression; Experimental and computational studies by Nader jadid, Ali Asghar Moshtaghie, Hashem Nayeri, Masoud Foladgar, Maryam Ostadsharif

    Published 2025-02-01
    “…The present study examines the effects of silver nitrate on the activity of the enzyme alkaline phosphatase (ALP) and its regulatory influence on inflammatory cytokines, specifically interleukin-10 (IL-10) and tumor necrosis factor-alpha (TNF-α). …”
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  13. 533

    Correlation between Serum IL-35 Levels and Bone Loss in Postmenopausal Women with Rheumatoid Arthritis by Yuxuan Li, Lutian Yao, Siyan Liu, JishengWu, Liping Xia, Hui Shen, Jing Lu

    Published 2019-01-01
    “…Furthermore, serum IL-35 levels in the increased ALP group were higher than those in the normal ALP group. …”
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  14. 534

    The Conditioned Medium of Calcined Tooth Powder Promotes the Osteogenic and Odontogenic Differentiation of Human Dental Pulp Stem Cells via MAPK Signaling Pathways by Jintao Wu, Na Li, Yuan Fan, Yanqiu Wang, Yongchun Gu, Zehan Li, Yin Pan, Gobin Romila, Zuomin Zhou, Jinhua Yu

    Published 2019-01-01
    “…Both the gene and protein (DSPP/DSPP, RUNX2/RUNX2, OCN/OCN, OSX/OSX, OPN/OPN, ALP/ALP, and COL-1/COL-1) expression levels increased in the CTP-CM-induced hDPSC group as compared with those in the control group at day 3 or 7, showing the positive regulation of CTP-CM on the osteo/odontogenic differentiation of hDPSCs. …”
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  15. 535

    Dopamine Suppresses Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells via AKT/GSK-3β/β-Catenin Signaling Pathway by Zhili Kuang, Zheng Chen, Shaoqin Tu, Zhihui Mai, Lin Chen, Xiaoning Kang, Xiaochuan Chen, Jiaming Wei, Yuxuan Wang, Yun Peng, Hong Ai

    Published 2022-01-01
    “…Interestingly, dopamine suppressed the osteogenic differentiation of rBMSCs, as characterized by reduced ALP staining, ALP activity, mineralized nodule formation, and the mRNA and protein levels of osteogenesis-related genes (Col1a1, Alp, Runx2, Opn, and Ocn). …”
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  16. 536

    The impact of serum testosterone level to reflect age-related multi-organ functions by Tomoya Shirakawa, Julius Fink, Zen-u Hotta, Yosuke Shimada, Yan Lu, Junhua Du, Kazuhito Matsushita, Satoshi Hori, Hisamitsu Ide, Shigeo Horie

    Published 2024-03-01
    “…Significant correlations (p &lt; 0.05) were found between total testosterone and Hb, Hct, LH, FSH, ALP, ALB, TG, HDL-C, AST, ALT, Glu, and CRP. In addition, significant correlations (p &lt; 0.05) were found between Hb, Hct, LH, FSH, ALP, ALB, TG and HDL-C associated with [age × testosterone]. …”
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  17. 537

    hMSC成骨分化相关lncRNA的筛选和初步鉴定 by 罗嘉全

    Published 2014-01-01
    “…uc003ups)与成骨基因Smurf-1相关;2个lncRNA(AF289591和uc003xbe)与成骨基因BMP1相关;1个lncRNA(AK056311)与成骨基因MSX1相关?ALP检测示:与对照组细胞相比,成骨诱导组细胞1周ALP值最高,达到(16.82 ± 1.64)nmol/min,随着诱导时间的延长,ALP值逐渐降低,3周降至(8.37 ± 1.01)nmol/min?…”
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