Retinoic Acid Signal Negatively Regulates Osteo/Odontogenic Differentiation of Dental Pulp Stem Cells by Jiangyi Wang, Guoqing Li, Lei Hu, Fei Yan, Bin Zhao, Xiaoshan Wu, Chunmei Zhang, Jinsong Wang, Juan Du, Songlin Wang

“…Activation of RA signal in vitro inhibited ALP activities and mineralization of human DPSCs and decreased the mRNA expression of ALP, osteocalcin, osteopontin, and a transcription factor, osterix. …”
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Effectiveness of purple leaves (Graptophyllum pictum L. Griff) and hydroxyapatite as socket preservation biomaterials by Ratri Maya Sitalaksmi, Rizkipriyanto Azharpratomo, Shafira Ninditya Irsan, Primanda Nur Rahmania, Sisca Meida Wati, Syafira Salsabila Adam, Kavanila Bilbalqish, Khairul Anuar bin Shariff, Harry Laksono, Agus Dahlan, Devi Rianti

“…Conclusion: The combination of nanosuspension extract of Purple leaves and hydroxyapatite was able to enhance the expression of RUNX2, OSX, OPN, ALP, and calcium deposition on days 7,14,21.…”
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Role and mechanism of dexmedetomidine in regulating bone metabolism in tail-suspended osteoporotic rats by GUO Yunliang, WANG Can, ZHANG Xinyu

“…The in vitro experiments showed that Dex treatment obviously improved ALP activity and the number of ALP-positive osteoblasts in primary osteoblasts isolated from tail-suspended rats (P<0.01), and up-regulated the expression levels of osteogenic differentiation-related genes, such as Ocn, Runx2, Osx and Col1 (P<0.01). …”
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Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regenerati... by Ayako Washio, Chiaki Kitamura, Takahiko Morotomi, Masamichi Terashita, Tatsuji Nishihara

“…BMP-2 had no effects on the morphology, growth, or ALP activity of KN-3 cells, whereas it induced the phosphorylation of Smad1/5/8 and expression of Smad6/7. …”
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Engagement in computerized cognitive training instructions by older people. A within-subject design to evaluate comprehension and acceptability of serious games instructions by Christelle Nahas, Marc Gandit, Emmanuel Monfort

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Foreword to New developments in passive seismic imaging and monitoring by Shapiro, Nikolai M., Campillo, Michel, Obermann, Anne, Curtis, Andrew

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Reply by Denis Vincent, MD, PhD, Ludovic Martin, MD, PhD, Sven Cichon, PhD, Christian Drouet, PharmD, PhD, Arije Ghannam, MD PhD

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Therapeutic effects of NAC and CoQ10 on aluminium phosphide poisoning as an adjuvant therapy: A Pilot study by Maii Farag Henaidy, Maha Ghanem, Shehata Farag Shehata, Amal M. Shouair, Reda R. Mabrouk

“…In aluminium phosphide (AlP) poisoning, death is mainly due to acute heart failure. …”
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GDF11 restores the impaired function of EPCs-MA by promoting autophagy: GDF11 ameliorates endothelial progenitor cell aging by promoting autophagy by Liu Donghua, Zhang Yang, Liu Xin, Huang Qihe, Zhang Xiaofang, Yang Rui, Zhao Yue, Li Penghui, He Jiayi, Zhang Kexiao, Pan Zhenwei, Liu Huiwen, Yang Baofeng

“…Our study aimed to assess the effects of Growth and differentiation factor 11 (GDF11) on the function of endothelial progenitor cells in middle-age individuals (EPCs-MA) isolated from mouse bone marrow and to explore the mechanistic relationship between GDF11 and age-related ALP impairment.…”
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Les poilus parlaient patois by Jean-Baptiste Martin

“…An in-depth research resulted in the collection of about fourty of them in the Rhône-Alpes region. This wide range of texts (letters, poems, dramas, patriotic songs, prose) brings a new perspective on the Great War.…”
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Photonic topological Anderson insulator in a two-dimensional atomic lattice by Skipetrov, Sergey E., Wulles, Pierre

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Elevated Liver Function Tests as Predictors of Severe Maternal Outcomes in Women with Preeclampsia by Sadia Chaudhary, Hafiza Ateeqa Mubarak, Anila Sabir, Hina Sadaf, Anas Khalil, Zahid Mahmood, Marium Shoukat, Farah Naz Tahir

“…Liver function tests (AST, ALT, and ALP) were measured upon diagnosis. Severe maternal outcomes were statistically analyzed using SPSS version 26 applying a paired t-test. …”
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Evaluation of Hepatoprotective Potential of Polyherbal Preparations in CCl4-Induced Hepatotoxicity in Mice by Rayhana Begum, Sonia Akther Papia, Mst Marium Begum, Hongbin Wang, Rubaba Karim, Rebeka Sultana, Priyanka Rani Das, Taslima Begum, Md. Ragibul Islam, Nargis Manwar, Md. Sohanur Rahman

“…CCl4 administration caused significant hepatotoxicity as evidenced by marked elevation in AST, ALT, ALP, and total bilirubin. Phenobarbitone-induced sleeping time and infiltration of inflammatory cells and centrizonal necrosis on histological examination of liver demonstrated hepatic injury after CCl4 administration. …”
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Animal-based evidence supports protective activity of bioengineered silver and gold nanomaterials on hepatic and renal function profile parameters by Hamed Barabadi, Hesam Noqani, Maha Soltani, Ayeh Sabbagh Kashani

“…In diseased animal models, biosynthesized NPs significantly reduced ALT, AST, ALP, urea, and creatinine levels, demonstrating their protective effects. …”
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How NaCl addition destabilizes ionic liquid micellar suspension until phase separation by Dufrêche, Jean-François, Plazanet, Marie, Meyer, Gautier, Billard, Isabelle

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The evolutionary dynamics of plastic foraging and its ecological consequences: a resource-consumer model by Ledru, Léo, Garnier, Jimmy, Guillot, Océane, Faou, Erwan, Noûs, Camille, Ibanez, Sébastien

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Opportune detections of global P-wave propagation from microseisms interferometry by Boué, Pierre, Tomasetto, Lisa

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Infusion line contamination in preterm neonates: impact of infusion line design, length, and use duration: the multicenter ChronoBIOline study by Sandra Dos Santos, Anne-Sophie Valentin, Mathilde Farizon, Manon Charbonneau, Mohamed Riadh Boukhris, Roselyne Brat, Fabiana Cazzorla, Jennifer Chauvel, Fabrice Cneude, Pauline Coutable, Maryvonne Demasure, Emeline Duminil, Vénonique Faraut-Derouin, Maud Gits Muselli, Valérie Gorin, Rosemary Goujon, Melinda Guillouche-Puissant, Nadine Hacinlioglu, Caroline Landelle, Annick Lefebvre, Elise Leroy-Terquem, Aurore Martinet, Camille Massebeuf, Nadia Mazille Orfanos, Guillaume Menard, Laure Menvielle, Vanessa Monin, Virginie Morange, Juliana Patkai, Nathalie Perrault, Emilie Prat, Nathalie van der Mee-Marquet

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Osteodifferentiation of Human Preadipocytes Induced by Strontium Released from Hydrogels by Valeria Nardone, Sergio Fabbri, Francesca Marini, Roberto Zonefrati, Gianna Galli, Annamaria Carossino, Annalisa Tanini, Maria Luisa Brandi

“…The osteoinductive effect was evaluated through both the expression of alkaline phophatase (ALP) activity and the hydroxyapatite (HA) production during 42 days of induction. …”
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Effect of Withania Somnifera Root Powder on the Levels of Circulatory Lipid Peroxidation and Liver Marker Enzymes in Chronic Hyperammonemia by B. Harikrishnan, P. Subramanian, S. Subash

“…Ammonium chloride treated rats showed a significant increase in the levels of circulatory ammonia, urea, AST, ALT, ALP, TBARS and HP. These changes were significantly decreased in rats treated with W.somnifera root powder and ammonium chloride. …”
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