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    Alteration in Oxidative Stress Enzymes and Proteins by Datura metel Stramonium Hydroethanolic Root Extract Promotes Hippocampus and Cerebral Cortex Neurons Damage in Adult Sprague... by oboma YI, Eberechukwu GC

    Published 2025-01-01
    “…Yibala Ibor oboma,1,2 God’sman C Eberechukwu1,3 1Department of Medical Laboratory Science, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University Wilberforce Island Bayelsa State, Amassoma, Nigeria; 2Department of Medical Laboratory Science, School of Allied Health Sciences, Kampala International University, Ishaka Municipal, Uganda; 3Department of Histopathology and Cytopathology, Faculty of Medical Laboratory Science, Federal University, Otuoke, Bayelsa State, NigeriaCorrespondence: Yibala Ibor oboma, Department of Medical Laboratory Science, School of Allied Health Sciences, Kampala International University, Western Campus, Bushenyi District, Ishaka Municipal, Uganda, Tel +256740059020, Email yibaaoboma@kiu.ac.ugBackground: Datura metel is reported to induce hallucinations and mental disorders.Objective: This study investigates the neurotoxic effects of Datura metel stramonium hydroethanolic root extract on the hippocampus and cerebral cortex of adult rats using biochemical, histological and immunohistochemical techniques.Methodology: Twenty five adult rats were assigned to 5 groups (n = 5 each). …”
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