Safety and effects of anti-obesity medications on weight loss, cardiometabolic, and psychological outcomes in people living with overweight or obesity: a systematic review and meta... by Leiling Liu, Zhiqi Li, Wenrui Ye, Pu Peng, Yurong Wang, Luqing Wan, Jiangnan Li, Mei Zhang, Yihua Wang, Runqi Liu, Danyan Xu, Jingjing Zhang

“…Semaglutide (RR 0.83, 0.74–0.92; P < 0.0001; I2 = 0.0%; high certainty) and liraglutide (0.87, 0.79–0.96; P = 0.0059; I2 = 0.0%; high certainty) reduced the risk of major adverse cardiovascular events (MACEs). However, all three medications were associated with adverse gastrointestinal effects. …”
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Steady-state mixing state of black carbon aerosols from a particle-resolved model by Z. Zhang, Z. Zhang, J. Wang, J. Wang, J. Wang, J. Wang, N. Riemer, C. Liu, C. Liu, Y. Jin, Y. Jin, Z. Tian, Z. Tian, J. Cai, J. Cai, Y. Cheng, Y. Cheng, G. Chen, G. Chen, B. Wang, B. Wang, S. Wang, A. Ding, A. Ding

“…Our result shows that aerosol compositions, coating thickness (CT) distribution, and optical properties of BC aerosols all exhibit a tendency toward a steady state with a characteristic timescale of less than 1 d, considerably shorter than the BC atmospheric lifetime. …”
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Genome sequencing enhances the diagnostic yield and expands the genetic landscape of male breast cancer by Wen Wen, Sen Zhao, Yiwen Jiang, Chengzhu Ou, Changyuan Guo, Ziqi Jia, Jiayi Li, Yansong Huang, Hengyi Xu, Pengming Pu, Tongxuan Shang, Lin Cong, Xiang Wang, Nan Wu, Jiaqi Liu

“…Results: The GS analysis unveiled previously unrecognized pathogenic/likely pathogenic germline variants in BARD1, ATR, BRIP1, and CHEK2 (HGNC: 952, 882, 20473, 16627) among 21 BRCA1/2-negative patients with MBC, elevating the diagnostic yield from 12.5% to 33.0% in all MBC. Elevated average polygenic risk score was noted compared with controls, with a significant correlation to early-onset MBC when combined with high-penetrance germline pathogenic variants (P = 1.10 × 10−4). …”
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Self-Normalized Moderate Deviations for Degenerate <i>U</i>-Statistics by Lin Ge, Hailin Sang, Qi-Man Shao

“…Let <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mo>{</mo><msub><mi>X</mi><mi>i</mi></msub><mo>,</mo><mi>i</mi><mo>≥</mo><mn>1</mn><mo>}</mo></mrow></semantics></math></inline-formula> be i.i.d. random variables and consider symmetric and degenerate kernel functions in the form <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>h</mi><mrow><mo>(</mo><mi>x</mi><mo>,</mo><mi>y</mi><mo>)</mo></mrow><mo>=</mo><msubsup><mo>∑</mo><mrow><mi>l</mi><mo>=</mo><mn>1</mn></mrow><mo>∞</mo></msubsup><msub><mi>λ</mi><mi>l</mi></msub><msub><mi>g</mi><mi>l</mi></msub><mrow><mo>(</mo><mi>x</mi><mo>)</mo></mrow><msub><mi>g</mi><mi>l</mi></msub><mrow><mo>(</mo><mi>y</mi><mo>)</mo></mrow></mrow></semantics></math></inline-formula>, where <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>λ</mi><mi>l</mi></msub><mo>></mo><mn>0</mn></mrow></semantics></math></inline-formula>, <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>E</mi><msub><mi>g</mi><mi>l</mi></msub><mrow><mo>(</mo><msub><mi>X</mi><mn>1</mn></msub><mo>)</mo></mrow><mo>=</mo><mn>0</mn></mrow></semantics></math></inline-formula>, and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>g</mi><mi>l</mi></msub><mrow><mo>(</mo><msub><mi>X</mi><mn>1</mn></msub><mo>)</mo></mrow></mrow></semantics></math></inline-formula> is in the domain of attraction of a normal law for all <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>l</mi><mo>≥</mo><mn>1</mn></mrow></semantics></math></inline-formula>. …”
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The Conceptual Domain of Hunting and Its Negative Representation in Love: A Cognitive-Cultural Analysis by Raheleh Gandomkar, Masoomeh Hashemi

“…Three micro metaphors obtained were “marriage is hunting,” “marriage is theft,” and “marriage is captivity,” which through linguistic metaphoric expressions such as hunting, snapping, enthralling, grabbing, snatching, ensnaring, catching, trapping, capturing, enslaving, and harnessing all bearing a negative emotional connation both in the case of man or the woman. …”
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Analysis of Foreign Tourists’ Behavioral Patterns and Perceptions in Rural Destinations by Hamdollah Sojasi Gheidari, Zahra Soleymani

“…The analysis was conducted through visual content analysis of the photos taken by tourists. All rural areas of Iran with photos published on Flickr by tourists were included in the study. …”
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Jiedu Xiaozheng Decoction Augments 5-fluorouracil Induced Anti-hepatic Carcinoma Effect <italic>in Vitro</italic> and <italic>in Vivo</italic> by Zhiyun CAO, Liangpu ZHENG, Wei LIN, Xuzheng CHEN, Xiaoqin ZHU, Jiumao LIN, Wei LIN, Jian DU

“…Objective:Up to now, morbidity and mortality of hepatocellular carcinoma(HCC)have been increasing all over the world especially in China.5-fluorouracil(5-FU)is a common used chemotherapy drug for many types tumor in clinic including HCC. …”
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Association of exposure to second-hand smoke during childhood with blood DNA methylation by Marta Cosin-Tomas, Thanh Hoang, Cancan Qi, Giulietta S. Monasso, Ryan Langdon, Simon Kebede Merid, Lucinda Calas, Paula de Prado-Bert, Rebecca Richmond, Vincent VW Jaddoe, Liesbeth Duijts, John Wright, Isabella Annesi-Maesano, Regina Grazuleviciene, Marianna Karachaliou, Gerard H. Koppelman, Erik Melén, Olena Gruzieva, Martine Vrijheid, Paul Yousefi, Janine F. Felix, Stephanie J. London, Mariona Bustamante

“…Nine CpGs were mapped to genes (MYO1G, FAM184B, CTDSPL2, LTBP3, PDE10A, and FIBCD1), while 2 CpGs were located in open sea regions. Notably, all except 2 CpGs (mapped to FIBCD1 and CTDSPL2) have previously been linked to either personal smoking habits or in utero exposure to smoking. …”
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Perspective of Need for First Aid Education in Bulgarian Schools by Daniela Baleva

“…Methods: A sample of 419 teachers from 26 public and private schools in different cities, towns, and villages in all the six NUTS 2 level regions in Bulgaria filled in questionnaires in order to examine their current level of first aid and disaster response training and motivation for improving it. …”
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MINDS. JWST-MIRI Observations of a Spatially Resolved Atomic Jet and Polychromatic Molecular Wind toward SY Cha by Kamber R. Schwarz, Matthias Samland, Göran Olofsson, Thomas Henning, Andrew Sellek, Manuel Güdel, Benoît Tabone, Inga Kamp, Pierre-Olivier Lagage, Ewine F. van Dishoeck, Alessio Caratti o Garatti, Adrian M. Glauser, Tom P. Ray, Aditya M. Arabhavi, Valentin Christiaens, R. Franceschi, Danny Gasman, Sierra L. Grant, Jayatee Kanwar, Till Kaeufer, Nicolas T. Kurtovic, Giulia Perotti, Milou Temmink, Marissa Vlasblom

“…We find a wide semiopening angle, high temperature, and low column density for the H _2 emission, all of which are characteristic of a disk wind. …”
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概念為本跨領域課程發展之研究—以國際文憑組織中學階段課程為例 Concept-Based Interdisciplinary Curriculum Development in International Baccalaureate Schools in Taiwan– The International Baccalaureate Middle Years... by 洪麗卿 Li-Ching Hung, 劉美慧 Meihui Liu, 王俐蘋 Li-Ping Wang

“…The distinctive value of the two case schools, as explored in this study, lays in their implementation of the IB curriculum on a school-wide basis and across all grade levels (instead of as an additional program or in a limited number of experimental classes). …”
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Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... by Amy Robinson, Kamaljit Khalsa, Arjun Chandna, John Bowen, Viva Levee, Jan Coebergh, Tom Solomon, Clive Graham, David Turner, Robert Tilley, Tim Jones, Susan Hopkins, Matthew Stevens, Daniel White, Celestine Eshiwe, Anna Goodman, Ramandeep Singh, Robert S Heyderman, Nicholas Davies, Joseph Thompson, Ed Moran, Martin Williams, Rhea O’Regan, Simon Tiberi, Jonathan Lambourne, Naomi Bulteel, Susan Larkin, Ruth McEwen, Hassan Paraiso, Aarti Shah, Martin Wiselka, Sylviane Defres, Ernest Mutengesa, Maria Krutikov, Ruth Owen, David Griffith, David Harvey, Trupti Patel, Brendan Davies, Emma Mclean, Joanna Allen, Ali Khan, Alastair Miller, Ashutosh Deshpande, Christopher Green, Lewis Jones, Mark Melzer, Fiona McGill, Amanda Fife, Nimal Wickramasinghe, Stephanie Harris, Ewan Hunter, Jayne Ellis, Benedict Rogers, Imogen Fordham, Elen Vink, Victoria Ward, Anna Smith, Andrew Rosser, Alison Muir, Ken Woodhouse, John Shone, Iain Crossingham, Ryan Jayesinghe, Eavan Muldoon, Avneet Shahi, Terry John Evans, Jeremy Wong, Eloisa MacLachlan, Amy Chue, Karishma Gokani, Katherine Ajdukiewicz, Lucinda Barrett, Frances Edwards, Adam Usher, Mairi McLeod, Su su Htwe, Grace Duane, Nicholas Wong, Jennifer Poyner, Jenni Crane, Ollie Lloyd, Emma Chisholm, Ildiko Kustos, Sam Sutton, M. Estee Torok, Isobel Ramsay, Monica Ivan, Joshua York, Jennifer Ansett, Maithili Varadarajan, Priya Sekhon, James Cruise, Shivani Kanabar, Mirella Ling, Charlotte Milne, Jayanta Sarma, Aline Wilson, Lynn Urquhart, Sahar Eldirdiri, Leila White, Jody Aberdein, Phillip Simpson, Hnin Hay Mar, Keying Tan, Eint Shwe Zin thein, Mahmoud Aziz, Anthony Cadwgan, Natasha Weston, Salman Zeb, Angela Houston, Louise Wootton, Iona Willingham, Aimee Johnson, Ashley Horsley, Eamonn Trainor, Olivier Gaillemin, Nicholas J Norton, Katie Cheung, Megan Duxbury, Emilie Bellhouse, Helena Brezovjakova, Kanitkar Tanmay, Alexsander Dawidziuk, Razan Saman, Hugh Adler, Elshadai Ejere, Yiwen Soo, Wendy Beadles, Heather Sturgeon, Brodie Cameron, David Chadwick Ben Tomlinson, Claire McGoldrick, Katie McDowell, Mpho Molosiwa, Katherine FlackAdrian Kennedy, Phoebe Cross, Fay Perry, Vithusha Inpadhas, Sarathy Selvam, Vhairi Bateman, Henry Wu, Monika Pasztor, Ajanthiha Karunakaran, Basma Soliman, Andrew Blanshard, Harish Reddy, Helen Chesterfield, Ben Schroeder, Tee Keat Teoh, Sathyavani Subbarao, Caryn RosmarinLucy Bell, Emma McGuire, Robert Serafino, Ishaan Bhide, Karanjeet Sagoo, Indran Balakrishnan, Kajal Patel, Barzo Faris, Graeme Calver, Ricky Singh, Hazel Sanghvi, Mohamed Eltayeb, Rathur Haris

“…Objectives To assess practice in the care of adults with suspected community-acquired bacterial meningitis in the UK and Ireland.Design Retrospective cohort study.Setting 64 UK and Irish hospitals.Participants 1471 adults with community-acquired meningitis of any aetiology in 2017.Results None of the audit standards, from the 2016 UK Joint Specialists Societies guideline on diagnosis and management of meningitis, were met in all cases. With respect to 20 of 30 assessed standards, clinical management provided for patients was in line with recommendations in less than 50% of cases. 45% of patients had blood cultures taken within an hour of admission, 0.5% had a lumbar puncture within 1 hour, 26% within 8 hours. 28% had bacterial molecular diagnostic tests on cerebrospinal fluid. …”
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The pattern of elementary teachers' insight in online education, using foundational data theory by reyhaneh bazrafshan delijan, Mohammad Ghafari Mejlej, seyyed javad mortazavi amiri

“…School-based management had a favorable situation in all the indicators mentioned in the evaluation. …”
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The effect of climate change on the simulated streamflow of six Canadian rivers based on the CanRCM4 regional climate model by V. K. Arora, A. Lima, R. Shrestha

“…Mean annual precipitation (<span class="inline-formula"><i>P</i></span>), evaporation (<span class="inline-formula"><i>E</i></span>), runoff (<span class="inline-formula"><i>R</i></span>), and temperature increase for all six river basins in both future scenarios considered here, and the increases are higher for the more fossil-fuel-intensive RCP 8.5 scenario. …”
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Review of Commercial Documents from Mohammad Ibrahim Malek Al-Tojjar Esfahani Company by Hasan Zandiyeh, Arefe Soleymani

“…Furthermore, the endowment of all of Malek al-Tojjar's assets, including the archives, to charitable causes had prevented their transfer to national archives, thus limiting the availability of resources and expertise.This study was among the first to explore the commercial activities of Malek al-Tojjar. …”
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The Role of Iranians in Istanbul in Publishing and Distributing Modernist and Constitutionalist Texts by Mohammad Hossein Sadeghi, Hassan Hazrati

“…By paying attention to Iranian publishers in the Ottoman Empire, the study described how they played a role in the production and transmission of texts containing modernism and constitutionalism aspects.Although all texts containing the idea of constitutionalism were banned by the Ottoman government, Iranian publishers published these texts illegally and delivered them to Iranian and Turkish audiences through various channels. …”
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Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa by Fredros Okumu, Sarah J. Moore, Prashanth Selvaraj, Arnon Houri Yafin, Elijah O. Juma, GloriaSalome G. Shirima, Silas Majambere, Andy Hardy, Bart G. J. Knols, Betwel J. Msugupakulya, Marceline Finda, Najat Kahamba, Edward Thomsen, Ayman Ahmed, Sarah Zohdy, Prosper Chaki, Peter DeChant, Kimberly Fornace, Nicodem Govella, Steven Gowelo, Emmanuel Hakizimana, Busiku Hamainza, Jasper N. Ijumba, William Jany, Hmooda Toto Kafy, Emmanuel W. Kaindoa, Lenson Kariuki, Samson Kiware, Eliningaya J. Kweka, Neil F. Lobo, Dulcisária Marrenjo, Damaris Matoke-Muhia, Charles Mbogo, Robert S. McCann, April Monroe, Bryson Alberto Ndenga, Halfan S. Ngowo, Eric Ochomo, Mercy Opiyo, Richard Reithinger, Chadwick Haadezu Sikaala, Allison Tatarsky, David Takudzwa, Fedra Trujillano, Ellie Sherrard-Smith

“…LSM contributions are also evidenced by the widespread use of LSM strategies in nearly all countries that have successfully achieved malaria elimination. …”
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Effects of rumen fluid transplantation on the fecal flora of yaks by Man Zhang, Man Zhang, Man Zhang, Yan Li, Yumin Li, Yumin Li, Yumin Li, Chenxu Cheng, Chenxu Cheng, Chenxu Cheng, Shatuo Chai, Shatuo Chai, Shatuo Chai, Yingkui Yang, Yingkui Yang, Yingkui Yang, Xun Wang, Xun Wang, Xun Wang, Shuxiang Wang, Shuxiang Wang, Shuxiang Wang

“…Separate single-pen rearing was performed in two pens using the same rearing environment and feeding method, and all yaks were earmarked for identification. In addition, 10 yaks that had been adapted to stall fattening feed in 1 month were selected as the rumen fluid donor group to provide fresh rumen fluid. …”
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Isolation Number of Transition Graphs by Junhao Qu, Shumin Zhang

“…Let <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>G</mi><mo>=</mo><mo>(</mo><mi>V</mi><mo>,</mo><mi>E</mi><mo>)</mo></mrow></semantics></math></inline-formula> be a graph and <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="script">F</mi></semantics></math></inline-formula> be a family of graphs; a subset (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>S</mi><mo>⊆</mo><mi>V</mi><mo>(</mo><mi>G</mi><mo>)</mo></mrow></semantics></math></inline-formula>) is said to be an <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi mathvariant="script">F</mi></semantics></math></inline-formula>-isolating set if <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>G</mi><mo>[</mo><mi>V</mi><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow><mo>∖</mo><msub><mi>N</mi><mi>G</mi></msub><mrow><mo>[</mo><mi>S</mi><mo>]</mo></mrow><mo>]</mo></mrow></semantics></math></inline-formula> does not contain <i>F</i> as a subgraph for all <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>F</mi><mo>∈</mo><mi mathvariant="script">F</mi></mrow></semantics></math></inline-formula>. …”
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Effects of Conditioning Temperature on Pellet Quality, Nutrients Digestibility, and Metabolizable Energy of Broilers Diet by Seyedeh Vajiheh Shakhese Emampour, Abolghasem Golian, Heydar Zarghi, Ali Reza Hesabi Nameghi

“…The electrical energy usage (EEU) of the pellet mill motors during the pellet diets predation were recorded. All pellet diets were sampled after production to test for pellet quality. …”
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