Beyond Dermatological Findings: Multisystem Involvement in Prolidase Deficiency by Ezgi Yalcin Gungoren, Zeynep Meric, Asena Pinar Sefer, Asuman Deveci Ozkan, Salim Can, Royala Babayeva, Nurhan Kasap, Ercan Nain, Esra Ozek Yucel, Ayca Kiykim, Sevgi Bilgic-Eltan, Ayse Deniz Yucelten, Elif Karakoc-Aydiner, Ahmet Ozen, Safa Baris

“…Lymphocyte subgroup analysis showed an inverted CD4/CD8 ratio in all patients. In patients P1 and P2, the percentages of naive T cells and recent thymic emigrants were reduced, suggesting combined immune deficiency at the time of diagnosis. …”
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Loop33 × 123 CAR-T targeting CD33 and CD123 against immune escape in acute myeloid leukemia by Haotian Ma, Zhifeng Yan, Runxia Gu, Yingxi Xu, Shaowei Qiu, Haiyan Xing, Kejing Tang, Zheng Tian, Qing Rao, Min Wang, Jianxiang Wang

“…Methods Based on our previously constructed CD33 and CD123 monovalent CAR-T, Loop33 × 123 and Loop123 × 33 CAR-T were constructed with molecular cloning techniques. All CAR-T cells were generated by lentivirus transduction of T cells from healthy donors. …”
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Generation of a USP9Y knockout human embryonic stem cell line with CRISPR-Cas9 technology by Sai Wei, Yuting Zhen, Chao Sun, Yanlin Ma, Qi Li, Luan Wen

“…The modified line retained pluripotency markers, exhibited a normal karyotype, and differentiated into all three germ layers. This model provides a valuable platform for studying USP9Y’s role in human development and male infertility, offering insights into related disorders and therapeutic potential.…”
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Screening of Genes Related to Resistance to Bacterial Leaf Blight in Oryza officinalis by using RNA-seq Technology by Yayun YANG, Feifei ZHANG, Famei ZHANG, Xinxiang A, Chao DONG, Cuifeng TANG, Chunyun YANG, Luyuan DAI

“…There were 20 O. officinalis materials resistant to two strains simultaneously, accounting for 66.67% of all materials. O. officinalis 37 showed moderate susceptibility to both strains, while O. officinalis 36 showed resistance to both strains. …”
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Editorial by Ann-Kristin Kölln, Antony Mason, Jörg Tremmel, Markus Rutsche, Maria Lenk

“…Overall, Paulis, similar to Stockemer and Sundström, suggests a review of institutional processes and structures within established political organisations such as parties in order to promote a more diverse and above all younger profile of politically active citizens. …”
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Antenatal Care - How to ensure quality! by Lubna Ejaz

“…Some of the major factors adversely affecting the ANC quality are poor infrastructure of the healthcare system12, lack of well-trained human resources13, insufficient preventive services14, and inefficient utilization of available resources at all levels. Lack of health awareness and poor compliance by patients and their families are other major social contributors towards this grim situation15. …”
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Frailty assessment in adults undergoing allogeneic hematopoietic cell transplantation: insights from a multicenter GETH-TC study to optimize outcomes and care by María Queralt Salas, María Teresa Solano, Mónica Baile González, Marina Acera Gómez, Laura Fox, María del Mar Pérez Artigas, Ana Santamaría, María del Carmen Quintela González, Andrés Sánchez Salinas, Joaquina M. Salmerón Camacho, Verónica Illana Álvaro, Zahra Abdallahi-Lefdil, Javier Cornago Navascues, Laura Pardo, Sara Fernández-Luis, Leddy Patricia Vega Suárez, Sara Villar, Patricia Beorlegui-Murillo, Albert Esquirol, Isabel Izquierdo García, Sonia Rodríguez González, Alberto Mussetti, Esperanza Lavilla, Javier Lopez-Marín, Silvia Filaferro, Ángel Cedillo, Leyre Bento, Leyre Bento, Anna Sureda, Anna Sureda

“…Data was collected prospectively and all patients signed informed consent.ResultsAt first consultation, 102 (26.2%) patients were classified as fit, 248 (61.4%) as pre-frail, and 50 (12.4%) as frail. …”
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Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort studyResearch in context by Jack L. Janetzki, Jung Ho Kim, Evan Minty, Jung Ah Lee, Daniel R. Morales, Rohan Khera, Chungsoo Kim, Thamir M. Alshammari, Scott L. DuVall, Michael E. Matheny, Thomas Falconer, Seonji Kim, Thanh-Phuc Phan, Phung-Anh Nguyen, Min-Huei Hsu, Jason C. Hsu, Rae Woong Park, Kenneth K.C. Man, Sarah Seager, Mui Van Zandt, James P. Gilbert, Patrick B. Ryan, Martijn J. Schuemie, Marc A. Suchard, George Hripcsak, Nicole Pratt, Seng Chan You

“…Analyses were subjected to pre-defined study diagnostics, and only those passing all diagnostics were reported. Hazard ratios (HRs) were pooled using Bayesian random-effects meta-analysis. …”
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Chronic Airflow Limitation, Lower Respiratory Symptoms, COPD and Chronic Rhinosinusitis in a Middle-Aged Population: The Swedish CArdioPulmonary bioImage Study (SCAPIS). A Link Bet... by Andersson A, Bergqvist J, Schiöler L, Bossios A, Farnebo L, Holmlund T, Janson C, Keceli S, Ljunggren M, Malinovschi A, Memarian E, Nihlén U, Nilsson PM, Pesonen I, Sjöström M, Stenfors N, Sundbom F, Werner M, Torén K, Sköld M, Hellgren J

“…The current study investigates the relationships between CRS and chronic airflow limitation (CAL), lower airway symptoms and COPD in a middle-aged population of ever-smokers and never-smokers.Patients and Methods: All subjects from the Swedish CArdioPulmonary bioImage Study (SCAPIS) were included. …”
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油脂对植物基冰淇淋乳液性质及产品品质的影响 "Effect of vegetable oil on the properties of plant-based ice cream emulsion and the quality of products" by 张贵金1，范军营2，尹永智2，逯彩云2，张晖1， 王兴国1，吴港城1 ZHANG Guijin1, FAN Junying2, YIN Yongzhi2, LU Caiyun2, ZHANG Hui1, WANG Xingguo1, WU Gangcheng1"

“…The appropriate solid fat content and higher medium-chain fatty acid content of hydrogenated coconut oil led to the formation of dense needle-like crystals, which more easily penetrated the interfacial membrane and increased the collision frequency of fat globules, promoting partial aggregation of fats in the ice cream. All ice cream emulsions were non-Newtonian fluids, and after the addition of modified soy protein isolate and freezing stirring, fat flocculation and partial aggregation occurred, significantly increasing the viscosity of the ice cream emulsion. …”
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Oncolytic virus OH2 extends survival in patients with PD-1 pretreated melanoma: phase Ia/Ib trial results and biomarker insights by Juan Li, Xuan Wang, Li Zhou, Jun Guo, Lu Si, Bixia Tang, Chuanliang Cui, Xiaoting Wei, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Caili Li, Xiangyong Gu, Binlei Liu, Hui Tian, Han Hu

“…NCT04386967 is the clinical trial identifier.Results All 44 patients were enrolled. OH2 was well tolerated without serious adverse events (AEs) or deaths reported. …”
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Profil Kasus Tuberkulosis Paru di Instalasi Rawat Inap Paru RSUP Dr. M. Djamil Padang Periode 1 Januari 2010 - 31 Desember 2011 by Muhammad Gamal Eddin, Oea Khairsyaf, Elly Usman

“…This research is a analytic descriptive that use secondary datas, which is medical records of PTB patients. The populations are all cases of pulmonary TB in Pulmonary Instalations Dr. …”
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ABO-incompatible liver transplantation – exploring utilitarian solutions to restricted access and organ shortages: A single-centre experience from Johannesburg, South Africa by E U Wessels, J Loveland, H Maher, P Gaylard, B Bobat, A D Mahomed, D Parbhoo, M R Beretta, C Hajinicolaou, P Walabh, S Berkenfeld, D Demopoulos, S Rambarran, B Ströbele, F van der Schyff, J Fabian, L Brannigan

“…This retrospective record review compared all adult and paediatric patients receiving ABO-compatible (ABOc) and ABO-incompatible (ABOi) liver transplants from January 2014 to December 2021 with a minimum one-year follow-up. …”
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Research Status and Prospects of Key Technologies for Rice Smart Unmanned Farms by YU Fenghua, XU Tongyu, GUO Zhonghui, BAI Juchi, XIANG Shuang, GUO Sien, JIN Zhongyu, LI Shilong, WANG Shikuan, LIU Meihan, HUI Yinxuan

“…Soil nutrient detection technology is mainly detected by electrochemical analysis and spectral analysis, but both methods have their advantages and disadvantages, how to integrate the two methods to achieve an all-round detection of soil nutrient content is the main direction of future research. …”
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UNCOVER: The Rest-ultraviolet to Near-infrared Multiwavelength Structures and Dust Distributions of Submillimeter-detected Galaxies in A2744 by Sedona H. Price, Katherine A. Suess, Christina C. Williams, Rachel Bezanson, Gourav Khullar, Erica J. Nelson, Bingjie Wang, John R. Weaver, Seiji Fujimoto, Vasily Kokorev, Jenny E. Greene, Gabriel Brammer, Sam E. Cutler, Pratika Dayal, Lukas J. Furtak, Ivo Labbe, Joel Leja, Tim B. Miller, Themiya Nanayakkara, Richard Pan, Katherine E. Whitaker

“…While these objects reveal a diversity of structures and sizes, all are smaller and more concentrated toward longer wavelengths. …”
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STRUCTURAL AND FUNCTIONAL STATE OF THE MYOCARDIUM AND SYSTEMIC INFLAMMATION ACTIVITY IN PATIENTS WITH ACUTE ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION IN THE PRESENCE OF ARTERIAL H... by Rostyslav Kovalchuk, Uliana Bahan

“…Hypertension was present in 46 patients, and a history of COVID-19 in 26 (67,64 (56,14- 78,17) % and 38,24 (27,12-50,01) %; 17 patients had both risk factors, their proportion in the total sample was 25,00 (15,51-35,90) %. All patients underwent conventional examinations in accordance with local clinical protocols. …”
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La flore sauvage du boulevard Dr Henri-Henrot à Reims/Durocortorum : approche carpologique de l’environnement du site et des productions de denrées végétales by Véronique Matterne, Clémence Pagnoux

“…Nevertheless, the significant variability in condition and setting should be highlighted, as the index includes all values from 1 to 9, a state also recorded for many rural sites of the Roman period in northern France (Zech-Matterne, Brun 2016). …”
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Implementation of in utero laparotomy-assisted fetoscopic spina bifida repair in two centers in Latin America: rationale for this approach in this regionAJOG Global Reports at a Gl... by Jezid Miranda, PhD, Miguel A. Parra-Saavedra, PhD, William O. Contreras-Lopez, PhD, Cristóbal Abello, MD, Guido Parra, MD, Juan Hernandez, MD, Amanda Barrero, MD, Isabela Leones, MD, Adriana Nieto-Sanjuanero, MD, Gerardo Sepúlveda-Gonzalez, MD, Magdalena Sanz-Cortes, PhD

“…Hydrocephalus treatment requirements at 12 months were similar across all groups. No maternal deaths or other outcomes such as pulmonary edema or need for maternal transfusion were noted in the fetoscopic SB repair group. …”
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Effectiveness of a physiotherapist-led triage and treatment service on WAITing time for adults with musculoskeletal pain referred to Australian public hospital physiotherapy clinic... by Ian A Harris, Andrew Lawson, Bethan Richards, Chris G Maher, Laurent Billot, David Roberts, Chris Needs, David Anderson, Nadine E Foster, Danielle Coombs, Marnee McKay, Joshua R Zadro, Tarcisio F de Campos, Michael Swain, Daniel Treacy, Lisa A Harvey, Gustavo Machado, Jackie Chu, Christopher S Han, Andrew R Gamble, Timothy Shaw, Mark Halliday, Joshua M Hutton, Tom Lung, Lisa Gridley, Joshua Wakefield

“…Participants at high risk of poor outcomes and/or with potential nonprogressive radiculopathy will be offered a course of usual clinic-based physiotherapy as per all participants in the usual care group. Physical function (Patient Specific Functional Scale) at 6 months postrandomisation and waiting time (time from randomisation to first treatment) are coprimary outcomes. …”
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Outcomes of endometrial cancer prevention strategies in patients with Lynch syndrome: a nationwide cohort study in the NetherlandsResearch in context by Ellis L. Eikenboom, Lotte van Leeuwen, Floris Groenendijk, Jorien M. Woolderink, Anne M. Van Altena, Monique E. Van Leerdam, Manon C.W. Spaander, Helena C. van Doorn, Anja Wagner, M.C. Breijer, A.S. Tjalsma, F. Vork, H.P.M. Smedts, J. van der Velden, M.M.A. Brood-van Zanten, J.E. van de Riet, A.L.M. Oei, H. Kessel, P.M.L.H. Vencken, M.P.L.M. Snijders, R.H.M. Hermans, A. Bouman, H.W. Ünsalan, A.M.G. van de Swaluw, G.M. Plaisier, H.C. van Doorn, K. van den Berg, W. Hofhuis, Y.A.J.M. Dabekausen, P.R. Kolk, H.T.C. Nagel, A.M.L.D. van Haaften-de Jong, A.C. van Hof, M. van den Hende, J. Kaijser, H.H. de Haan, R.A. Smit, M.W.G. Moonen-Delarue, J.J. Beltman, J.E. Martens, R. Kruitwagen, J.M. van der Ploeg, J.M. Woolderink, S.F.P.J. Coppus, M.J. Duk, M.J.A. Apperloo, C.M. Koopmans, C.C.M. Buis, H. van Meurs, E.C. Dul, B.B.J. Hermsen, A.M. van Altena, A. Baalbergen, A.A. van Ginkel-Terng, M. Baas, P. van Greunen, C.M.W.H. Smeets, H. Knipscheer, J.E. Martens, C. Schmeink, M.D. van der Laan, E.J.M. van Es, J.E.W. van Dijk, F.M.F. Rosier-van Dunné, H. Nijman, C.G. Gerestein, D. Boskamp, E.C.A.H. Scheers, M. Verbruggen, L.R. Bartelink, C.B.M. Kruijdenberg, J.M. Briët, B. Visschers, M. Engelen

“…Overall survival after endometrial carcinoma diagnosis did not differ between carriers with or without surveillance or carriers with endometrial carcinoma before LS diagnosis (p = 0.51). For all endometrial carcinomas together, including index carriers, cumulative incidence was 22.7% at age 70. …”
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