Biodegradable Mg alloy modified with bioactive exosomes for cardiovascular stent application by Ya-chen Hou, Jing-an Li, Chang Cao, Chang Su, Zhen Qin, Ge Zhang, Jia-cheng Guo, Jun-nan Tang, Jin-ying Zhang, Shao-kang Guan

“…In addition, the MgF2-PDA/exosome coating also improved the adhesion, proliferation, CD31 expression and nitric oxide (NO) release of vascular endothelial cells (ECs), all of which contribute to the surface endothelialization. …”
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Practice of continuing care with Traditional Chinese Medicine nursing for patients after surgical treatment of mixed hemorrhoids in the specialized outpatient clinic (基于专病门诊的混合痔术后患... by Qin Shasha (秦沙沙), E Haiyan (鄂海燕), WEI Yongchun (魏永春), PENG Yujie (彭雨洁), TANG Ling (唐玲), LI Ye (李野), WANG Yali (王亚丽), DONG Yuxia (董玉霞)

“…Methods Totally 80 patients undergoing surgical treatment of mixed hemorrhoids of Damp-Heat type were randomly divided into the observation group and the control group, with 40 cases in each group. All patients received routine perioperative nursing during hospitalization. …”
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Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

“…Despite having opposed epigenetic functions, these mutations are associated with increased all-cause mortality and a low risk for progression to hematologic neoplasms. …”
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Computed tomography-guided microwave ablation for right middle lobe pulmonary nodules: a retrospective, single-center, case-control study by Yanting Hu, Guoliang Xue, Xinyu Liang, Zhichao Li, Nan Wang, Pikun Cao, Gang Wang, Haitao Zhang, Xiaohuan Zheng, Aiguang Wang, Wenhua Zhao, Cuiping Han, Zhigang Wei, Xin Ye

“…The duration of the procedure and post-ablation hospital stay were also recorded.Results Technical success was achieved in 100% of all patients. There were no significant differences in technique efficacy rates between the RML and non-RML groups (97.2% vs. 95.1%, p = 0.721). …”
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Interaction of human gut microbiota and local immune system in progression of colorectal adenoma (MIMICA-1): a protocol for a prospective, observational cohort study by Jurate Valciukiene, Egle Lastauskiene, Aida Laurinaviciene, Aida Laurinaviciene, Matas Jakubauskas, Marius Kryzauskas, Ruta Barbora Valkiuniene, Ruta Barbora Valkiuniene, Renaldas Augulis, Renaldas Augulis, Ausra Garnelyte, Justinas Kavoliunas, Ugne Silinskaite, Tomas Poskus

“…DNA will be extracted from all samples and sequenced using the Illumina MiSeq platform. …”
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Effect of Xingbi Gel Nasal Drops on Rats with Allergic Rhinitis Based on the Nasal Mucosa-Hippocampus Neuroimmune Mechanism by FAN Xueqi, QIU Caixia, YAN Shuiping, ZHUANG Xiangli, AI Si, GUO Lihua, ZHENG Jian

“…Compared with the normal group, the nasal mucosal EOS counts all significantly increased in the model group, the traditional Chinese medicine group and the western medicine group after treatment (<italic>P</italic>&lt;0.05); compared with the model group, the nasal mucosa EOS counts decreased significantly in the traditional Chinese medicine group and the western medicine group after treatment (<italic>P</italic>&lt;0.05). (5) mRNA transcription levels and protein expression levels of Fyn, SP, VIP and NPY in hippocampus: compared with the normal group, mRNA transcription levels of Fyn, SP and VIP and average OD values of Fyn, SP and VIP increased significantly in the hippocampus in the model group (<italic>P</italic>&lt;0.05), while mRNA transcription levels of NPY and average OD values of NPY decreased significantly (<italic>P</italic>&lt;0.05). …”
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Scaling and intermittent properties of oceanic and atmospheric <i>p</i>CO₂ time series and their difference in a turbulence framework by K. Robache, F. G. Schmitt, Y. Huang, Y. Huang

“…Scaling exponents are estimated through Fourier analysis, and their average quantities were considered globally for all parameters, as well as for different ecosystems such as coastal shelf, coral reefs and open ocean. …”
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A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders by Marta Di Forti, Benjamin W. Bond, Edoardo Spinazzola, Giulia Trotta, Jodie Lynn, Richard Malkin, Naba Kamran Siddiqui, Sultan Demir, Titilayomi Opadokun, Perry B.M. Leung, Zhikun Li, Andrea Quattrone, Gabriella Baxter, Elizabeth Appiah-Kusi, Tom P. Freeman, Hannah Walsh, Tommaso Squeri, Daria Semikina, Felicity Amberson-Jones, Isabelle Austin-Zimmerman, Tim Meynen, Diego Quattrone, Robin M. Murray

“…Significant improvements in all clinical and functional outcomes were observed, with 90.70% being in work or education at T1 compared with 8.70% at T0. …”
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Geological and Geochemical Characteristics of the First Member of the Cretaceous Qingshankou Formation in the Qijia Sag, Northern Songliao Basin, Northeast China: Implication for I... by Fei Xiao, Jianguo Yang, Shichao Li, Fanhao Gong, Jian Zhang, Yulai Yao, Ang Li, Liyan Zhang, Yiming Huang, Fei Su, Yunfeng Bai

“…(ii) The average OSI (oil saturation index) values of K2qn11, K2qn12, and K2qn13 are 110.54 mg/g, 171.74 mg/g, and 150.87 mg/g, respectively, which all reach the zone of oil crossover. The saturated hydrocarbon of EOM (extractable organic matter) in K2qn12 and K2qn13 is of higher content than that in K2qn11, while it is the opposite for the aromatic hydrocarbon, nonhydrocarbon, and asphaltene, indicating better oil mobility for K2qn12 and K2qn13. …”
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Navigating healthcare pathways: Cascade of prevention and care for chronic viral hepatitis in asylum seekers and refugees. A multicenter analysis in Northern Italy by Beatrice Formenti, Roberto Benoni, Jacopo Testa, Giulia Bertoli, Giacomo Stroffolini, Maria Grazia Pizzi, Barbara Menzaghi, Niccolò Ronzoni, Paola Magro, Issa El Hamad, Carla Scolari, Angiola Spinetti, Serena Zaltron, Francesco Castelli, Valentina Marchese, Alberto Matteelli

“…Of 1,514 participants, 80.2 % underwent screening, with 87.3 % testing negative for all infections. For those with chronic infections, 20.8 % missed their first infectious disease consultation, and only 39.3 % were retained in care after one year. …”
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Release velocity ImprovemenT with a new Metronome guIding chest COmpressions: The RITMICO simulation study by Maria Luce Caputo, Giuliana Monachino, Ruggero Cresta, Alessia Currao, Enrico Baldi, Simone Savastano, Andrea Cortegiani, Mariachiara Ippolito, Sara Accetta, Alessandra Gargano, Camilla Metelmann, Bibiana Metelmann, Carlos Ramon Hölzing, Julian Ganter, Michael Patrick Müller, Claudio Benvenuti, Stefania Tomola, Pierangelo Pinetti, Pier Luigi Ingrassia, Francesca Dalia Faraci, Angelo Auricchio

“…The double-click metronome led to significant improvements in CC depth and CCRV across all volunteer categories, with the greater effect observed in first responders and in non-specialized healthcare personnel. …”
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Satellite quantification of methane emissions from South American countries: a high-resolution inversion of TROPOMI and GOSAT observations by S. E. Hancock, D. J. Jacob, Z. Chen, H. Nesser, A. Davitt, A. Davitt, D. J. Varon, M. P. Sulprizio, N. Balasus, L. A. Estrada, M. Cazorla, L. Dawidowski, S. Diez, J. D. East, E. Penn, C. A. Randles, C. A. Randles, J. Worden, I. Aben, R. J. Parker, R. J. Parker, J. D. Maasakkers

“…Our estimates align with the prior estimates for Brazil, Bolivia, and Paraguay but are significantly higher for other countries. Emissions in all countries are dominated by livestock (mainly enteric fermentation) except for oil–gas in Venezuela and landfills in Peru. …”
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Seasonality of host-seeking Ixodes ricinus nymph abundance in relation to climate by Hoch, Thierry, Madouasse, Aurélien, Jacquot, Maude, Wongnak, Phrutsamon, Beugnet, Fréderic, Bournez, Laure, Cosson, Jean-François, Huard, Frédéric, Moutailler, Sara, Plantard, Olivier, Poux, Valérie, René-Martellet, Magalie, Vayssier-Taussat, Muriel, Verheyden, Hélène, Vourc’h, Gwenaël, Chalvet-Monfray, Karine, Agoulon, Albert

“…The peak occurred in summer for the mountainous site, with an absence of ticks in winter. In all cases except the mountainous site, the timing of the spring peak could be related to the sum of degree days since the beginning of the year. …”
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Potential Antidepressant Effects of Omeprazole Introduced Through Network Analysis and Systems Biology Should Be Interpreted with Caution in the Clinical Environment by Seyed-Ali Mostafavi

“…Furthermore, malabsorption of magnesium, calcium, and B vitamins may occur, which are all important in maintaining optimal brain function and mood stability. …”
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Utility of Noninvasive Testing Before Invasive Coronary Angiography in the Assessment for Revascularization by Simon Parlow, MD, Richard G. Jung, MD, PhD, Pietro Di Santo, MD, Joanne Joseph, MD, Stephanie Skanes, MD, Omar Abdel-Razek, MD, Graeme Prosperi-Porta, MSc, MD, Pouya Motazedian, MD, Michael Froeschl, MSc, MD, Marino Labinaz, MD, Rebecca Mathew, MD, F. Daniel Ramirez, MSc, MD, Trevor Simard, MD, PhD, Benjamin Hibbert, MD, PhD

“…Patients and Methods: We screened all patients who received ICA between August 1, 2015, and July 31, 2019, and identified those who received MPI or CTA within the preceding 12 months. …”
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Apheresis for the treatment of relapses in MS and NMOSD: reduced antibody reactivities, gene expression changes and potential clinical response indicators by Michael Hecker, Brit Fitzner, Isis Ludwig-Portugall, Friederike Bohne, Edmar Heyland, Juliane Klehmet, Matthias Grothe, Matthias Schwab, Alexander Winkelmann, Stefanie Meister, Ales Dudesek, Hannah Wurm, Ilya Ayzenberg, Ingo Kleiter, Ingo Kleiter, Corinna Trebst, Martin W. Hümmert, Bernhard Neumann, Bernhard Neumann, Klaus Eulitz, Dirk Koczan, Uwe K. Zettl

“…In contrast, MS patients who underwent apheresis (nmax=27) showed strong immunoglobulin reduction rates, especially for IgG, and decreased antibody reactivities against all tested peptides. EBNA1 (amino acids 391-410) was the only peptide that also reached the significance level in NMOSD patients (n=9). …”
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Assessing environmental change and population declines of large wading birds in southwestern India by K.M. Aarif, Aymen Nefla, K.A. Rubeena, Yanjie Xu, Zakher Bouragaoui, M. Nasser, C.T. Shifa, T.R. Athira, K. Jishnu, Jasmine Anand, Seerangan Manokaran, P.P. Moosa, Anu Gopinath, Omer R. Reshi, K.M. Rajaneesh, H. Byju, Thadickal V. Joydas, Karuppasamy P. Manikandan, Mohd Irfan Naikoo, Christian Sonne, Sabir Bin Muzaffar

“…These variables cover climatic variables (rainfall), sediment variables (salinity, pH, organic carbon, nitrogen, phosphorus), water variables (Salinity, pH, temperature, nitrate, phosphate), primary productivity (Chlorophyll-a) and prey availability (mean fish stock availability). Densities of all the studied wader species decreased significantly from 2010 to 2019, with highest densities in agroecosystems or estuarine habitats and in post-monsoon seasons but lowest in mudflats and in monsoon seasons. …”
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Influence of enteral nutrition support via nasointestinal tube combined with fast-truck surgery on nutritional status, complications and postoperative rehabilitation of patients wi... by LU Huixin (卢卉欣)

“…Methods Totally 100 patients with severe head injury were divided into the control group (n=58) and the observation group(n=42) according to the nutrition support methods. All patients received nursing interventions based on the theory of fast-truck surgery. …”
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Using the HBSC Symptom Checklist to measure junior secondary school students’ psychosomatic complaints in the Chinese Mainland: Rasch-based validation, population-based norm, and n... by Yuhang Zhu, Xianzhu Cong, Zhenliang Qiu, Ricky Jeffrey, Ranran Li, Li Jing, Gaopei Zhu, Xi Yang, Shuang Li, Jinling Wang, Xu Xu, Hongliu Zhu, Xinjian Wang, Ling Huang, Xueqin Sun, Di Wu, Kai Zhang, Xunhong Miao, Rui Wen, Qinglang Huang, Zhuang He, Juan Li, Alina Cosma, Fuyan Shi, Suzhen Wang, the PROSQoL-JSSS research group

“…Evidence-based on the six features of the Rasch model indicated that the Mandarin Chinese HBSC-SCL has satisfactory psychometric properties. All 5-category rating scales of eight items appropriately differentiated the students’ PSC and demonstrated strong goodness-of-fit. …”
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Reliability of the OMERACT Giant cell arteritis Ultrasonography Score (OGUS): results of a patient-based exercise involving experts and non-experts in vascular ultrasonography by Christian Dejaco, Stavros Chrysidis, Sara Monti, Cristina Ponte, Peter Mandl, Lene Terslev, Bhaskar Dasgupta, Alojzija Hočevar, Christina Duftner, Wolfgang Schmidt, Carlos Pineda, Eugenio De Miguel, Andreas P Diamantopoulos, Helen Keen, Kati Mykkänen, George A Bruyn, Wolfgang Hartung, Maria Antonietta D’Agostino, Nikitas Gkikopoulos, Luca Seitz, Adela-Cristina Sarbu, Eva Manger, Berit Dalsgaard Nielsen, Norbert Redlinger, Veerendra Chadachan, Maria Correyero, Giovanni Fulvio, Vesselina Kurteva, Paolo Mercatelli, Irina Midtgard, Raili Muller, Duriad Reffat

“…Inter-reader and intra-reader reliability were assessed by intraclass correlation coefficient (ICC).Results Mean age of GCA patients was 78±5.1 years, 2 (33.3%) were women, and all were in clinical remission. Expert inter-reader ICC of the OGUS was 0.60 in both rounds, 0.40 in round 1 and 0.51 in round 2 for the Southend score and 0.45 and 0.52, respectively, for the Halo count. …”
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