Iodine-131 Combined With Plasma Exchange Treatment in Graves’ Hyperthyroidism Patients With Severe Liver Injury Whose Average Model for End-Stage Liver Disease Scores >20 by Xin-Fang Zhu, Rong-Rong Ding, Bing-Yao Wang, Yun-hui Yang, Fu-Xia Ta, Yuan Wang, Qing-Mei Gao, Qi Zhang, Rong Xia, Xing-Guang Luo, Xuan Wang, Jian-Ming Zheng, Hui-Qing Zhu

“…Methods: The patients who had hyperthyroidism caused by Graves’ disease, with severe liver injury (The level of total bilirubin ≥12 mg/dL), and after 1 week of liver protective medication treatment, the patient’s liver function did not improve, were enrolled in this study. All patients were treated with iodine-131 and PE. …”
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Effect of auricular holographic copper-plate scrapping combined with auricular acupoint pressing therapy in the treatment of nonspecific low back pain of cold-dampness obstruction... by REN Fang (任芳), ZHOU Haiying (周海英), BAI Yang (白洋), LI Lijuan (李利娟)

“…Methods Totally 90 patients with nonspecific low back pain of cold-dampness obstruction type were randomly divided into the control group and observation group, with 45 cases in each group. All patients received routine treatment and nursing, and those in the observation received auricular holographic copper-plate scrapping combined with auricular acupoint pressing therapy for three weeks. …”
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Genetic testing of ocular manifestations of proliferative syndrome to provide pathophysiology-oriented treatment by M.E. Weener, N.A. Bakunina, J.M. Salmasi, G.V. Poryadin, D. Barh, Yu.D. Kuznetsova, L.M. Balashova

“…Laboratory, genetic, and relevant clinical tests were pursued in all patients.</i> </p> <p> <i><b>Results</b>: proprietary approach of bioinformatic analysis of whole exome/whole genome sequencing data allows for specifying the proliferative process’s prognosis and severity given clinical and genetic findings. …”
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Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis by Daciana C. Dumut, Daciana C. Dumut, Marian Hajduch, Marian Hajduch, Amanda M. Zacharias, Qingling Duan, Qingling Duan, Ivo Frydrych, Zuzana Rozankova, Zuzana Rozankova, Miroslav Popper, Miroslav Popper, Dusan Garic, Radu Alexandru Paun, Radu Alexandru Paun, Amanda Centorame, Amanda Centorame, Juhi Shah, Martin Mistrik, Martin Mistrik, Petr Dzubak, Petr Dzubak, Juan B. De Sanctis, Juan B. De Sanctis, Danuta Radzioch, Danuta Radzioch, Danuta Radzioch, Danuta Radzioch

“…While the prior represents about 5% of all CRCs, the latter represent 95% and are characterized by low immunogenicity. …”
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Challenges with achieving and maintaining oral cholera vaccine coverage: insights from serial cross-sectional representative surveys in a cholera-endemic community in the Democrati... by Oliver Cumming, Andrew S Azman, Espoir Bwenge Malembaka, Jackie Knee, Placide Okitayemba Welo, Aimé Cikomola, Aybüke Koyuncu, Patrick Musole Bugeme, Juan Dent, Chloe Hutchins, Hanmeng Xu, Karin Gallandat, Joseph Matundanya, Delphin Rukakiza, Merveille Nkombo, Jaime Saidi Mufitini, Baron Bashige Rumedeka, Laurent Akilimali, Elizabeth C Lee

“…We used an exponential decay model to predict the proportion of the population vaccinated with ≥1 dose of kOCV over time based on age-specific coverage.Results We enrolled 8735 participants from 1433 households across all surveys. Coverage in survey 1 (August 2021) was 55% for ≥1 dose of kOCV (95% CI 51 to 60) and 23% for ≥2 doses (95% CI 20 to 27). …”
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Application of gastrointestinal decompression method in determining tip position of the triple-lumen nasointestinal tube in critically ill patients (胃肠减压法在危重症患者三腔鼻肠管位置判断中的应用)... by WANG Zhimin (王志民), LI Xuejing (李雪晶), QIAO Shouang (乔首昂)

“…Methods A retrospective analysis was conducted on the medical records of 120 critically ill patients with indwelling triple-lumen nasointestinal tubes from June 2020 to April 2022. All patients underwent blind insertion of a triple-lumen nasointestinal tube. …”
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Optimization of drying parameters and texture properties of winter jujube slices by radio frequency combined with hot air by Yang Li, Yang Li, Yang Li, Chenyan Yang, Chenyan Yang, Chenyan Yang, Shuaitao Cao, Shuaitao Cao, Shuaitao Cao, Ruijie Guan, Ruijie Guan, Ruijie Guan, Bowen Zhang, Bowen Zhang, Bowen Zhang, Xuedong Yao, Xuedong Yao, Xuedong Yao, Qiang Wang, Qiang Wang, Qiang Wang, Wancheng Dong, Wancheng Dong, Wancheng Dong, Yong Huang, Yong Huang, Yong Huang

“…The results showed as follows: (1) Plate spacing, RF application, and interval time all significantly affected the drying properties in the single-factor test (p &lt; 0.05). …”
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Decreased vitamin D increase the risk for subclinical hypothyroidism in individuals with T2DM: a cross-sectional study by Yaling Fang, Yaling Fang, Xin Wen, Hui You, Yueye Huang, Shen Qu, Xingchun Wang, Le Bu

“…Thyroid function was compared between groups and their association was analyzed.ResultsBody mass index (BMI), total cholesterol (TCH), triglyceride (TG), and free fatty acid (FFA) were significantly lower in the higher VD group compared to the lower VD group (all p &lt; 0.05). In the higher VD group, free triiodothyronine (FT3) levels were significantly elevated (4.45 ± 0.93 vs. 4.95 ± 1.52 ng/mL, p &lt; 0.001), while total triiodothyronine (TT4) (104.84 ± 21.17 vs. 99.99 ± 23.64 ng/mL, p = 0.008) and thyroid stimulating hormone (TSH) (2.88 ± 7.03 vs. 2.06 ± 1.72 ng/mL, p = 0.046) levels were significantly reduced compared to the lower VD group. …”
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MO-GCN: A multi-omics graph convolutional network for discriminative analysis of schizophrenia by Haiyuan Wang, Runlin Peng, Yuanyuan Huang, Liqin Liang, Wei Wang, Baoyuan Zhu, Chenyang Gao, Minxin Guo, Jing Zhou, Hehua Li, Xiaobo Li, Yuping Ning, Fengchun Wu, Kai Wu

“…We proposed a novel methodology of multi-omics graph convolutional network (MO-GCN) with an attention mechanism to construct a classification model by integrating all BGCGs. We also identified important brain and gut features using the Topk pooling layer and analyzed their correlations with the Positive and Negative Syndrome Scale (PANSS) and MATRICS Consensus Cognitive Battery (MCCB) scores. …”
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Development and validation of a model to predict cognitive impairment in traumatic brain injury patients: a prospective observational studyResearch in context by Xiaofang Yuan, Qingrong Xu, Fengxia Du, Xiaoxia Gao, Jing Guo, Jianan Zhang, Yehuan Wu, Zhongkai Zhou, Youjia Yu, Yi Zhang

“…Methods: The training cohort included 234 TBI patients, all of whom were admitted to the Department of Neurosurgery at the Third Affiliated Hospital of Soochow University from May 2017 to April 2020. …”
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Carriage of Extended-Spectrum-β-Lactamase- and AmpC-β-Lactamase-Producing Enterobacteriaceae (ESBL-PE) in Healthy Community and Outpatient Department (OPD) Patients in Nepal by Dipendra Kumar Mandal, Shiv Kumar Sah, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sanjeet Pandit, Pranav Kumar Yadav, Ujjwal Laghu, Rajani Lama, Niranjan Prasad Sah, Jeevan Bahadur Sherchand, Keshav Parajuli, Anup Bastola, Sher Bahadur Pun, Basista Prasad Rijal, Bharat Mani Pokharel

“…Similarly, E. coli remained the most frequent ESBL producers 21/27 (77.8%) followed by K. pneumoniae 4/27 (14.21%) in healthy participants, and K. pneumoniae 5/7 (71.42%) and C. freundii 2/7 (28.57%) were detected highest among AmpC-β-lactamase-producing isolates. All isolates were highly sensitive (100%) to imipenem in both OPD and healthy participants. …”
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THE ORGANIZATION WORKS TO IMPROVE THE CLINICAL AND ECONOMIC OUTCOMES OF CARE FOR PROSTATE CANCER by O. I. Apolikhin, A. V. Sivkov, I. V. Chernishov, M. I. Katibov, O. V. Zolotukhin, I. A. Shaderkin, S. A. Leonov, D. A. Vojtko, M. Y. Prosyannikov

“…From 2009 to 2013 an improvement of a number of indicators was marked: increase in the absolute number of patients with newly diagnosed prostate cancer from 451 to 603 cases, a localized increase in the share stages with 60.3% to 71.2 %, a decrease of deaths within one year from the date of diagnosis for prostate cancer from 14.6% to 6.5% and deaths among all registered patients with prostate cancer from 10.4% to 5.5%, reducing the proportion of clinically insignificant PCA from 36.4 to 14.1%.Conclusions. …”
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Multimodal neural correlates of childhood psychopathology by Jessica Royer, Valeria Kebets, Camille Piguet, Jianzhong Chen, Leon Qi Rong Ooi, Matthias Kirschner, Vanessa Siffredi, Bratislav Misic, BT Thomas Yeo, Boris C Bernhardt

“…Although model parameters yielded statistically significant brain–behavior associations in unseen data, generalizability of the model was rather limited for all three latent components (r change from within- to out-of-sample statistics: LC1within = 0.36, LC1out = 0.03; LC2within = 0.34, LC2out = 0.05; LC3within = 0.35, LC3out = 0.07). …”
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Diversity in the medical research ecosystem: a descriptive scientometric analysis of over 49 000 studies and 150 000 authors published in high-impact medical journals between 2007... by Leo Anthony Celi, Jonathan Shaffer, Marie-Laure Charpignon, Liam G McCoy, Luis Filipe Nakayama, Jack Gallifant, Urvish Jain, Joao Matos, Pia Gabrielle I Alfonso, Marisa Cobanaj, Amelia Morel Fiske, Alexander J Gates, Frances Dominique V Ho, Mohammad Kashkooli, Naira Link

“…To evaluate disparities in gender and geographical representation among authors who have published in any of five top general medical journals, we conducted scientometric analyses using a large-scale dataset extracted from the New England Journal of Medicine, Journal of the American Medical Association, The BMJ, The Lancet and Nature Medicine.Methods Author metadata from all articles published in the selected journals between 2007 and 2022 were collected using the DimensionsAI platform. …”
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Clinical Recommendations of Russian Gastroenterological Association and RENDO Endoscopic Society on Diagnosis and Treatment of Gastritis and Duodenitis by V. T. Ivashkin, I. V. Maev, T. L. Lapina, E. D. Fedorov, A. A. Sheptulin, A. S. Trukhmanov, A. V. Kononov, R. A. Abdulkhakov, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, E. K. Baranskaya, N. N. Dekhnich, I. L. Klyaritskaya, R. S. Kozlov, E. A. Kogan, M. P. Korolev, N. V. Korochanskaya, S. A. Kurilovich, M. A. Livsan, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, A. S. Sarsenbaeva, V. I. Simanenkov, A. S. Tertychny, A. V. Tkachev, Yu. P. Uspensky, I. B. Khlynov, V. V. Tsukanov

“…Oesophagogastroduodenoscopy (OGDS) or high-resolution OGDS with magnified or non-magnified virtual chromoendoscopy, including targeted biopsy for atrophy and intestinal metaplasia grading and neoplasia detection, are recommended to verify gastritis and duodenitis, precancer states and/or gastric mucosal changes. All chronic gastritis patients positive for H. рylori should undergo eradication therapy as aetiological and subsidiary for gastric cancer prevention. …”
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A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial by Xiaorong Wu, Alvin Surya Tjahyo, Vera Sergeyevna Brok Volchanskaya, Long Hui Wong, Xianning Lai, Yi Ning Yong, Farhana Osman, Shia Lyn Tay, Priya Govindharajulu, Shalini Ponnalagu, Rachel Tso, Hwee Sze Teo, Kaijie Khoo, Huan Fan, Chew Chan Goh, Clara Poh Lian Yap, Melvin Khee-Shing Leow, Christiani Jeyakumar Henry, Sumanto Haldar, Kevin Junliang Lim

“…Primary outcomes were markers of glycemia and all measurements were taken at 2 or 4-weekly intervals. …”
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QuickStroop for screening for minimal hepatic encephalopathy in patients with cirrhosis by Christian Labenz, Simon J. Gairing, Leonard Kaps, Alena F. Ehrenbauer, Eva M. Schleicher, Sophie Mengel, Julius F.M. Egge, Maria M. Gabriel, Peter R. Galle, Heiner Wedemeyer, Alexander Zipprich, Cristina Ripoll, Robin Greinert, Benjamin Maasoumy

“…MHE was defined using the psychometric hepatic encephalopathy score (PHES) (PHES-MHE). All patients were tested with the complete EncephalApp Stroop. …”
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Psychophysiological components of the activities of operators of nuclear power plants as a factor of accidents in the conditions of the threat of social catastrophe by O.A. Shevchenko, O.V. Sheviakov, V.V. Kornienko, I.A. Burlakova, Y.A. Slavska, N.I. Zhyhaylo, V.V. Vakulik, I.S. Ostapenko, O.A. Gerasimchuk, E.Y. Doroshenko, V.V. Prykhodko, S.A. Chernihivska, O.M. Ivchenko, V.M. Tychonovych, S.B. Dorogan

“…It was established that men only (100%) aged 24-49 and with work experience from 4 to 20 years were among the examined. All surveyed operators (41 people) are residents of the city, with completed higher education and are family members. …”
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Mechanisms of blaIMP-4 dissemination across diverse carbapenem-resistant clinical isolates by Ying Fu, Faye C. Morris, Stephanie C. Pereira, Xenia Kostoulias, Yan Jiang, Callum Vidor, Galain Williams, Yogi Srikhanta, Nenad Macesic, Yunsong Yu, Dena Lyras, Anton Y. Peleg

“…Sequence homology was observed across all plasmids at the blaIMP-4 location, termed Region I, with IS26 on IncHI2A, and IS5075 and Tn3 resistance gene cassettes present on IncC plasmids. …”
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The first experience with brolucizumab for neovascular age-related macular degeneration by A.N. Kulikov, D.S. Maltsev, A.Yu. Malafeeva, S.M. Perminova, V.R. Zhalimova, A.S. Vasiliev, A.A. Kazak

“…Group 2 included 34&nbsp; patients having active nAMD despite ongoing treatment/34 eyes (25 men and 9 women, mean age 74.1±8.0 years, mean BCVA 0.46±0.25). All patients received at least two intravitreal injections of brolucizumab (in&nbsp;total, 137&nbsp;injections) with a 1-month interval. …”
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