Minimal Invasive Versus Open Surgery for Colorectal Liver Metastases: A Multicenter German StuDoQ|Liver Registry-Based Cohort Analysis in Germany by Simon Moosburner, MD, Chiara Kettler, Karl H. Hillebrandt, MD, Moritz Blank, Hannes Freitag, Sebastian Knitter, MD, Felix Krenzien, MD, Nora Nevermann, MD, Igor M. Sauer, MD, Dominik P. Modest, MD, Georg Lurje, MD, Robert Öllinger, MD, Wenzel Schöning, MD, Jens Werner, MD, Maximilian Schmeding, MD, Johann Pratschke, MD, Nathanael Raschzok, MD, members of StuDoQ|Liver of Deutsche Gesellschaft für Allgemein- und Viszeralchirurgie/StuDoQ

“…Colorectal cancer is the third most common malignancy worldwide. Up to 50% of all patients with colorectal cancer develop CRLM. …”
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Előszó by Ákos Forczek

“…Prokk Balázs Boros egy Kierkegaard-tanulmányát gondolja tovább: A szeretet cselekedeteit boncolgató cikk fő állítása szerint a felebaráti szeretetben rejlő szimmetrikus viszony konfliktusban áll a szekuláris kormányzás szükségszerűen hierarchikus és aszimmetrikus viszonyrendszerével. …”
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Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study by Zhongchen Li, Chunyu Yu, Heng Zhang, Runze Chen, Yan Zhao, Zhe Zheng

“…Each 1-SD increase in remnant-C was associated with a 6.6% higher risk of MACCEs (HR: 1.066, 95% CI 1.012–1.124), a 7.1% higher risk of all-cause death (HR: 1.071, 95% CI 1.008–1.209), and an 11.2% higher risk of myocardial infarction (HR: 1.112, 95% CI 1.011–1.222). …”
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The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT by T. L. Antonevskaya, A. I. Khalimon, O. V. Mukhortova, M. M. Khodzhibekova, A. I. Nikiforuk, D. D. Zubkov, G. F. Khamadeeva, D. Yu. Khodakova, T. N. Lazutina, I. V. Pylova, A. V. Leontyev, I. P. Aslanidi

“…Scans were performed using three different PET/CT-systems: GE Discovery IQ Gen 2 (USA), Siemens Biograph 64 mCT and Biograph 64 TruePoint (Germany). All patients were divided into two groups: the group with hydration (n = 95, 53 %), which included the subgroups of patients with oral (n = 76, 80 %) and intravenous (n = 19, 20 %) routes of hydration, and the control group with no hydration (n = 85, 47 %). [18F]PSMA‑1007 uptake in the urinary bladder was quantified using SUVmean (Mean Standardized Uptake value), measured within a spherical VOI with a fixed volume of 2.5 cm3 delineating the bladder boundaries. …”
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Results from an Australopithecus africanus dental enamel fragment confirm the potential of palaeoproteomics for South African Plio-Pleistocene fossil sites by Palesa P. Madupe, Fazeelah Munir, Marc Dickinson, Alberto J. Taurozzi, Meaghan Mackie, Mirriam Tawane, Catherine Mollereau, Nomawethu Hlazo, Kirsty Penkman, Lauren Schroeder, Clément Zanolli, Jesper V. Olsen, Rebecca R. Ackermann, Enrico Cappellini

“…Lastly, we strongly believe that the involvement of African researchers at all levels of this research, including leadership, is of great importance. …”
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The potential of bacteriophage for controlling Vibrio parahaemolyticus as in-vitro by Bagus Ansani Takwin, Dinamella Wahjuningrum, Widanarni Widanarni, Hasan Nasrullah

“…However, the antibiotic control performed better than phage density treatments (0.61 ± 0.01). All phage density treatments effectively reduced V. parahaemolyticus density compared to the negative control, with the most favorable results observed in the FB9 treatment at a density of 109 PFU/mL.   …”
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Characterizing executive functioning and associated behaviors in individuals with dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) syndrome by Hannah M. Rea, Sara Jane Webb, Sara Jane Webb, Evangeline C. Kurtz-Nelson, Caitlin M. Hudac, Caitlin M. Hudac, Raphael A. Bernier, Conor Miles, Rachel Earl, Alana Whiting, Curtis Eayrs, Margaret Johansson, Tianyun Wang, Tianyun Wang, Tianyun Wang, Evan E. Eichler, Evan E. Eichler, Emily Neuhaus, Emily Neuhaus

“…Diagnostic overshadowing, or the tendency to attribute all problems to intellectual disability and to leave other co-existing conditions, such as executive functioning challenges or ADHD, undiagnosed, is common. …”
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Whole-genome sequencing reveals transmission pattern and drug resistance of Mycobacterium tuberculosis intra- or inter-hosts by Feng Ding, Wanfei Liu, Chi Wu, Chi Wu, Wensi Zhang, Shuyan Chen, Shuyan Chen, Wenjie Lai, Wenjie Lai, Jiayao Qu, Jiayao Qu, Qiang Lin, Shuihua Lu, Jiuxin Qu, Jiuxin Qu

“…The drug-resistant mutations in 36 of 45 transmission clusters (80.00%) were identical in all samples, suggesting the transmission of drug resistance. …”
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Serum IL-18 Is Increased at Early Postburn Period in Moderately Burned Patients

“…An increase in sera IL-<mml:math alttext="$6$"><mml:mn>6</mml:mn></mml:math>, IL-<mml:math alttext="$18$"><mml:mrow><mml:mn>18</mml:mn></mml:mrow></mml:math>, and TNF-<mml:math alttext="$alpha$"><mml:mi>&#x03B1;</mml:mi></mml:math> was detected at the <mml:math alttext="$48$"><mml:mrow><mml:mn>48</mml:mn></mml:mrow></mml:math>th hour postburn (<mml:math alttext="$P>.0001$"><mml:mrow> <mml:mi>P</mml:mi><mml:mo>&#x003C;</mml:mo><mml:mn>.0001</mml:mn></mml:mrow></mml:math>). All patients survived. A marked increase in serum levels of IL-<mml:math alttext="$18$"><mml:mrow><mml:mn>18</mml:mn></mml:mrow></mml:math> as well as the other cytokines evaluated was observed in the moderately burned patients. …”
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Unveiling chemical industry secrets: Insights gleaned from scientific literatures that examine internal chemical corporate documents-A scoping review. by Miaoran Dong, Marc-André Gagnon

“…Legal proceedings served as the primary source of internal document data for all examined articles. We uncovered and categorized dynamic strategies employed by chemical corporations to protect and advance their interests, including scientific capture (n = 16), regulatory capture (n = 15), professional capture (n = 7), civil society capture (n = 6), media capture (n = 4), legal capture (n = 4), technological capture (n = 3), and market capture (n = 2).…”
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Sorption and diffusion studies of radiocesium in soil samples from Ibu Kota Nusantara region of Indonesia by Hana Fikrinabilah Dely Supratman, Hendra Adhi Pratama, Budi Setiawan, Mochamad Adhiraga Pratama, Sucipta Sucipta, Sitti Hijraini Nur, Nurul Efri Ekaningrum, Gustri Nurliati, Moh. Cecep Cepi Hikmat, Andry Setiawan, Niken Siwi Pamungkas, Zico Pratama Putra, Muhammad Yusuf

“…The E sample offered the largest distribution coefficient (Kd) across all solvents, highlighting the significant impact of clay concentration on adsorption capacity. …”
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Deep immunophenotyping of circulating immune cells in major depressive disorder patients reveals immune correlates of clinical course and treatment response by Fabiola Stolfi, Claudio Brasso, Davide Raineri, Virginia Landra, Camilla Barbero Mazzucca, Ali Ghazanfar, Lorenza Scotti, Riccardo Sinella, Vincenzo Villari, Giuseppe Cappellano, Paola Rocca, Annalisa Chiocchetti

“…Traditional treatment strategies often follow a one-size-fits-all approach obtaining suboptimal outcomes for many patients who fail to experience response or recovery. …”
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Doctors taking bribes from pharmaceutical companies is common and not substantially reduced by an educational intervention: a pragmatic randomised controlled trial in Pakistan by Afifah Rahman-Shepherd, Johanna Hanefeld, Mishal Khan, Charles Opondo, Sameen Siddiqi, Virginia Wiseman, Iqbal Azam, Wafa Aftab, Sadia Shakoor, Amna Rehana Siddiqui, Rumina Hasan, Zafar Mirza, Muhammad Naveed Noor, Sabeen Sharif Khan, Nina van der Mark, Afshan Khurshid Isani, Ahson Q Siddiqi, Faisal Ziauddin, Faiza Bhutto, Natasha Ali, Robyna Irshad Khan, Syed Ahmed Raza Kazmi, Zainab Hasan

“…We developed a novel method using data collectors posing as pharmaceutical company sales representatives to evaluate private doctors’ engagement in incentive-linked prescribing and the impact of a multifaceted educational intervention on reducing this practice in Karachi, Pakistan.Methods We made a sampling frame of all doctors running for-profit, primary-care clinics and randomly allocated participants to control and intervention groups (1:1). …”
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On Bridge Graphs with Local Antimagic Chromatic Number 3 by Wai-Chee Shiu, Gee-Choon Lau, Ruixue Zhang

“…The local antimagic chromatic number <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>χ</mi><mrow><mi>l</mi><mi>a</mi></mrow></msub><mrow><mo>(</mo><mi>G</mi><mo>)</mo></mrow></mrow></semantics></math></inline-formula> is the minimum number of colors taken over all colorings induced by local antimagic labelings of <i>G</i>. …”
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Marine sponge symbiotic bacterial bioremediation against heavy metal pollutants in tiger prawns; Penaeus monodon culture medium by I. Marzuki, I. Pratama, R. Asaf, A. Athirah, K. Nisaa, N. Nurbaya, M. Muslimin, N. Nurhidayah, S. Suwardi, A. Sahrijanna, K. Kamaruddin

“…The health of the tiger prawns was evaluated by observing signs of tissue damage.FINDINGS: Among all the treatments, Treatment I with copper ion exposure had the highest average specific growth rate of the tiger prawns in terms of weight and body length, followed by Treatment II with lead ion exposure and Treatment III with a combination of both pollutants (the lowest). …”
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Clinical and genetic characteristics of a total or partial congenital aniridia by N.V. Sukhanova, V.V. Kadyshev, T.A. Vasilieva, A.V. Marakhonov, L.A. Katargina, S.I. Kutsev, R.A. Zinchenko

“…The mean age of patients was 11.5±10.3 years. All patients underwent a comprehensive eye exam, molecular and genetic testing, as well as specialist consultation. …”
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DS2 designer pre-fusion F vaccine induces strong and protective antibody response against RSV infection by Yiling Yang, Ruoke Wang, Fenglin Guo, Tian Zhao, Yuqing Lei, Qianqian Yang, Yige Zeng, Ziqing Yang, Tatchapon Ajavavarakula, Ruijie Tan, Mingxi Li, Haodi Dong, Mengyue Niu, Keyan Bao, Hao Geng, Qining Lv, Qi Zhang, Xuanling Shi, Peng Liu, Jiwan Ge, Xinquan Wang, Linqi Zhang

“…In this study, we generated three recombinant vaccines using the chimpanzee adenovirus vector AdC68 to express DS-Cav1, SC-TM, and DS2. All three vaccines elicited robust serum binding and neutralizing antibodies following intramuscular priming and boosting. …”
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Impact of HER2 Expression on the Prognosis of Muscle-Invasive Bladder Cancer Patients Treated with Bladder-Preservation Comprehensive Therapy by Yatong Chen, Fei Luo, Tingji Zhang, Jian Li

“…Methods We retrospectively collected information on MIBC patients. All 217 patients underwent cTURBT, of whom 175 received GC chemotherapy, while the remaining 42, due to intolerance to GC chemotherapy and HER2 positivity (IHC 2 + or 3 +), received RC48-ADC treatment. …”
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Pre-existing IgG antibodies to HCoVs NL63 and OC43 Spike increased during the pandemic and after COVID-19 vaccination by Zahra Hasan, Kiran Iqbal Masood, Marc Veldhoen, Shama Qaiser, Marta Alenquer, Mishgan Akhtar, Sadaf Balouch, Junaid Iqbal, Yaqub Wassan, Shahneel Hussain, Khalid Feroz, Sajid Muhammad, Atif Habib, Akbar Kanji, Erum Khan, Afsar Ali Mian, Rabia Hussain, Maria Joao Amorim, Zulfiqar A. Bhutta

“…Antibodies to SARS-CoV-2, NL63 and OC43 were all raised during the pandemic and further enhanced after COVID-19 vaccinations. …”
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Spondilitis Tuberkulosa Cervical by Roni Eka Saputra, Irsal Munandar

“…Keterlibatan spinal biasanya merupakan akibat dari penyebaran hema<br />Kata kunci: spondilitis TB, cervical, pembedahan<br /> <br />Abstract <br />Cervical tuberculous spondylitis is a fairly rare disease, only about 2-3% of all cases of tuberculous<br />spondylitis. The clinical features vary widely, ranging from mild and non-specific symptoms until the fatal neurological<br />complications. …”
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