Identifying pre-diabetes ‘hotspots’ in Northern California using geospatial analysis: opportunities to target diabetes prevention strategies and improve health equity by Tannaz Moin, Luis A Rodriguez, Obidiugwu Kenrik Duru, Julie Schmittdiel, Tainayah W Thomas, Maher Yassin, Yelba Castellon-Lopez

“…Census tracts within hotspots had lower levels of household income (HL estimate: −3651.00, 95% CI –7256.00 to –25.00), per cent of adults with bachelor’s degrees or higher (HL estimate: −9.08, 95% CI –10.94 to –7.24) and median home values (HL estimate: −113 200.00, 95% CI –140 600.00 to –85 700.00) and higher rates of household poverty (HL estimate: 0.96, 95% CI 0.55 to 1.37), unemployment (HL estimate: 0.39, 95% CI 0.24 to 0.54), household public assistance (HL estimate: 0.97, 95% CI 0.76 to 1.18) and per cent receiving Medicaid (HL estimate: 4.56, 95% CI 3.40 to 5.76) (p<0.05 for all).Conclusions We found that individual-level and census tract-level socioeconomic status, obesity prevalence and race and ethnicity categories of patients living in pre-diabetes hotspots differed from those not identified as a hotspot. …”
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Immuno-PET Imaging of the Programmed Cell Death-1 Ligand (PD-L1) Using a Zirconium-89 Labeled Therapeutic Antibody, Avelumab by Elaine M. Jagoda PhD, Olga Vasalatiy PhD, Falguni Basuli PhD, Ana Christina L. Opina PhD, Mark R. Williams BS, Karen Wong MS, Kelly C. Lane BS, Steve Adler PhD, Anita Thein Ton MS, Lawrence P. Szajek PhD, Biying Xu PhD, Donna Butcher BS, Elijah F. Edmondson DVM, PhD, Rolf E. Swenson PhD, John Greiner PhD, James Gulley MD, PhD, Janet Eary MD, Peter L. Choyke MD

“…The spleen and lymph nodes exhibited the highest [ 89 Zr]Zr-DFO-PD-L1 mAb uptakes in all time points, while MDA-MB231 tumor uptakes were lower but highly retained. …”
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Clinical determinants and prognostic implications of renin and aldosterone in patients with symptomatic heart failure by Masatake Kobayashi, Susan Stienen, Jozine M. terMaaten, Kenneth Dickstein, Nilesh J. Samani, Chim C. Lang, Leong L. Ng, Stefan D. Anker, Macro Metra, Gregoire Preud'homme, Kevin Duarte, Zohra Lamiral, Nicolas Girerd, Patrick Rossignol, Dirk J. vanVeldhuisen, Adriaan A. Voors, Faiez Zannad, João Pedro Ferreira

“…The primary outcome was the composite of all‐cause mortality or HF hospitalization. We also investigated changes in renin and aldosterone levels after administration of mineralocorticoid receptor antagonists (MRAs) in a subset of the EPHESUS trial and in an acute HF cohort (PORTO). …”
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Clinical analysis of microscopic modified ostium obstruction surgery for symptomatic sacral Tarlov cysts by HUANG Qin‐guo, WU Yan‐yu, LI Hong, ZHOU Qiang, PENG Lin, LU Yun‐tao

“…Results A total of 74 cysts were detected in 35 patients, among which 49 (66.26%) were large cysts (diameter > 1.50 cm), and cysts mainly compressed S1 nerve roots (22 cysts, 29.73%) and S2 nerve roots (36 cysts, 48.65%), all of which had fistulas and nerve roots passing through them. …”
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In situ simulation for cardiopulmonary resuscitation training: A systematic review by Andrea Cortegiani, Mariachiara Ippolito, Cristian Abelairas-Gómez, Sabine Nabecker, Alexander Olaussen, Kasper G. Lauridsen, Yiqun Lin, Taylor Sawyer, Joyce Yeung, Andrew S. Lockey, Adam Cheng, Robert Greif, Aaron Donoghue, Barbara Farquharson, Chih-Wei Yang, Heike Geduld, Kathryn Eastwood, Kevin Nation, Sebastian Sch naubelt, Tasuku Matsuyama, Ying-Chih Ko, Katherine S. Allen, Tracy Kidd, Jan Breckwoldt, Ming-Ju Hsieh

“…The certainty of evidence was very low for all the evaluated outcomes mainly due to risk of bias, inconsistency and imprecision. …”
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Work ability following breast cancer – the MyHealth randomized controlled trial by Trine A. Horsbøl, Lena Saltbæk, Caroline Urhammer, Randi V. Karlsen, Christoffer Johansen, Pernille E. Bidstrup, Beverley L. Høeg, Vibeke Zoffmann, Federica Belmonte, Ingelise Andersen, Anne S. Friberg, Mads N. Svendsen, Helle G. Christensen, Vesna Glavicic, Dorte L. Nielsen, Susanne O. Dalton

“…Differences in mean WAS between patients in MyHealth and control follow-up were non-significant and close to zero at all time points (–0.21 to 0.48). Interpretation: The MyHealth follow-up program had no additional effect on self-reported work ability compared to regular follow-up. …”
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Analysis of the spatiotemporal dynamics of vascular injury and regeneration following experimental Spinal Cord Injury by Christian J. Entenmann, Emily J. von Bronewski, Lilly Waldmann, Lea Meyer, Katharina Kersting, Laurens T. Roolfs, Lasse M. Schleker, Melina Nieminen-Kelhä, Irina Kremenetskaia, Frank L. Heppner, Michael G. Fehlings, Peter Vajkoczy, Vanessa Hubertus

“…Vascular proliferation (CD31+/Ki-67+) manifested across all regions at d3 (p < 0.01), and most notably in R2 (p < 0.01). …”
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Evaluating the impact of a tertiary multidisciplinary meeting in metastatic breast cancer: A prospective study by Belinda Sassé, Sammy Shaya, Jessica Nimmo, Katie Cao, Daphne Day, Katie Evans, Catherine Healy, Gwo-Yaw Ho, Gillian Kruss, Amelia McCartney, Linda Mojzisova, Ranjana Srivastava, Jennifer Tan, Mun Yee Tan, Kate Webber, Michelle White, Steven David, Marion Harris

“…Conclusion: MBC MDMs result in significant, actionable changes to patient management. 28.1 % of presentations resulted in treatment changes, almost all of which were implemented. Costs were offset by improved clinic efficiencies. …”
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Application of integrated traditional Chinese and western medicine nursing in rehabilitation of patients with hemiplegia after ischemic stroke (中西医结合护理干预在缺血性脑卒中偏瘫患者康复中的应用)... by HUANG Chaoping (黄朝萍), WANG Li (王丽), LI Yanmin (李艳敏), ZHANG Shuai (张帅), CHENG Jiangyan (程江艳), WANG Jing (王晶), QIU Yajiao (邱亚娇), LIANG Hui (梁慧)

“…According to the method of random number table, they were divided into control group and observation group, with 63 cases in each group. All patients received conventional drug treatment, routine care and rehabilitation training, and those in the observation group were given integrated traditional Chinese and western medicine nursing interventions. …”
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Effects of health education based on the theory of knowledge-attitude-practice on mental health and quality of life in patients with newly diagnosed primary liver cancer (基于知信行理论的健... by HE Cuijuan (何翠娟), WANG Jie (汪婕), ZHU Hengmei (朱恒美), YANG Yuan (杨远)

“…Methods Totally80 patients with primary liver cancer were selected as the study object, and 80 patients were randomly divided into control group (n=40) and the observation group (n=40). All patients received routine care and health guidance during the treatment, and patients in the observation group received KAP-based health education. …”
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Application of lacrimal gland ultrasonography in the evaluation of chronic ocular graft-versus-host-disease by Mingxia Zhong, Siyuan Liu, Jinghan Luo, Qin Zhang, Zhou Yang, Shanshan Zhang

“…Demographics and transplantation-related information were collected for all participants, including age, gender, donor-recipient HLA matching, donor-recipient ABO matching, donor-recipient gender combination and duration after allo-HSCT. …”
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Analisis Sentimen Kebijakan Penerapan Kurikulum Merdeka Sekolah Dasar dan Sekolah Menengah pada Media Sosial Twitter dengan Menggunakan Metode Word Embedding dan Long Short Term Me... by Alif Rizal Maulana, Satrio Hadi Wijoyo, Yusi Tyroni Mursityo

“…Abstract The COVID-19 pandemic has created many obstacles to all aspects of human life, including education. …”
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Impacts of genomic alterations on the efficacy of HER2-targeted antibody–drug conjugates in patients with metastatic breast cancer by Riqing Huang, Anqi Hu, Qixiang Rong, Ditian Shu, Meiting Chen, Wei Yang, Yue Zhang, Qiufan Zheng, Xin An, Cong Xue, Haifeng Li, Yanxia Shi

“…Additionally, ERBB2/CDK12 co-amplification exhibited a superior median PFS in all patients (19.33 months vs. 5.43 months; HR = 0.13; 95% CI 0.04–0.45; p < 0.001) and in HER2-positive patients (19.33 months vs. 6.87 months; HR = 0.18; 95% CI 0.05–0.72; p = 0.007). …”
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Optimizing Muscle Performance in Young Soccer Players: Exploring the Impact of Resisted Sprint Training and Its Relationship with Distance Covered by Felipe Hermosilla-Palma, Juan Francisco Loro-Ferrer, Pablo Merino-Muñoz, Nicolás Gómez-Álvarez, Rodrigo Zacca, Hugo Cerda-Kohler, Ciro Brito, Jorge Pérez-Contreras, Moacyr Portes-Junior, Esteban Aedo-Muñoz

“…Time-dependent differences were observed in all groups for peak force (PF) (<i>p</i> < 0.001; η²p = 0.62), time to PF (TPF) (<i>p</i> < 0.001; η²p = 0.53), impulse at 50 (<i>p</i> < 0.001; η²p = 0.57), 100 (<i>p</i> < 0.001; η²p = 0.60), and 200 ms (<i>p</i> < 0.001; η²p = 0.67) in IMTP; jump height by impulse-momentum (<i>p</i> < 0.001; η²p = 0.64), rate of force development (<i>p</i> = 0.04; η²p = 0.14), yielding impulse (<i>p</i> < 0.001; η²p = 0.49), and concentric impulse (<i>p</i> = 0.01; η²p = 0.19) in CMJ; time (<i>p</i> < 0.001; η²p = 0.46) in 505 m; and average speed in linear sprint (<i>p</i> = 0.003; η²p = 0.36), with moderate to large effect sizes, regardless of the distance covered. …”
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Remarkable Phytochemical Characteristics of Chi-Nan Agarwood Induced from New-Found Chi-Nan Germplasm of Aquilaria sinensis Compared with Ordinary Agarwood by Meng Yu, Yangyang Liu, Jian Feng, Deli Chen, Yun Yang, Peiwei Liu, Zhangxin Yu, Jianhe Wei

“…In addition, there were significant differences in the contents of low-molecular-weight aromatic compounds such as 2-methyl-4H-1-benzopyran-4-one, 4-methoxybenzaldehyde, and 2-hydroxybenzaldehyde between Chi-Nan agarwood and ordinary agarwood. All the mentioned main chemical characteristics of this new Chi-Nan agarwood were coincident with those of the rare wild Chi-Nan agarwood from A. malaccensis, A. sinensis, and A. crassna. …”
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The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…In conclusion, the increasing evidence of the important role of the sense of smell in many medical and psychological disorders could negatively affect social and working life of people of all social and economic strata, and, therefore, be relevant to public health field. …”

Reducing dietary crude protein levels while meeting metabolizable protein requirements: Performance of dairy cows over a full lactation period by A. Lavery, A. Craig, A.W. Gordon, A. White, N. Barkley, C.P. Ferris

“…ABSTRACT: A total of 90 Holstein dairy cows (24 primiparous, 66 multiparous, mean parity = 3.0) were fed diets containing either 150, 160, or 170 g CP/kg DM from 8 to 180 DIM, with all diets designed to supply at least 100% MP requirements. …”
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Evaluation of Yield and Yield Components of Different Ecotypes of Black Cumin (Nigella sativa L.) to Planting Date in Gorgan by Mohammad Sadeq Ashrafi, Farshid Ghaderi-Far, Elias Soltani, Ebrahim Zeinali, Asieh Siahmarguee

“…With the delay in planting, all measured traits decreased. The highest grain yield was obtained from the first planting date (December 18) with 1245 kg per ha. …”
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Navigating the Ice: Establishing Pre-Concussion Baselines in Ice-Hockey Players for Gait Assessment Utilizing Inertial Measurement Units by Julia Müller, Noah Köppel, Patrick Eggenberger, Emanuel Brunner, Thomas Weber, Eling D. de Bruin

“…Concussions represent 2–14% of all hockey injuries (Izraelski, 2014). Sports-related concussions (SRC) sustained in professional ice hockey are a common in-competition injury leading to highly individual return to sport that can be associated with symptoms lasting days to months (Höllerer et al., 2023). …”
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Attitudes of radiologists and interns toward the adoption of GPT-like technologies: a National Survey Study in China by Tianyi Xia, Shijun Zhang, Ben Zhao, Ying Lei, Zebin Xiao, Bingwei Chen, Junhao Zha, Yaoyao Yu, Zhijun Wu, Chunqiang Lu, Tianyu Tang, Yang Song, Yuancheng Wang, Shenghong Ju

“…Sensitivity analyses confirmed these results for different acceptance thresholds (all p < 0.001). Conclusions Chinese radiologists or interns generally support GPT-like technologies due to their potential capabilities in clinical practice, medical education, and scientific research. …”
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