Association between remnant cholesterol (RC) and endometriosis: a cross-sectional study based on NHANES data by Zeru Chen, Ruixuan Li, Jiajie Guo, Xiaorong Ye, Yang Zhou, Mingzhu Cao

“…Results After accounting for all potential confounders, a strong correlation between RC and EMs was identified. …”
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Differences in Arrhythmia Detection Between Harvard Step Test and Maximal Exercise Testing in a Paediatric Sports Population by Massimiliano Bianco, Fabrizio Sollazzo, Riccardo Pella, Saverio Vicentini, Samuele Ciaffoni, Gloria Modica, Riccardo Monti, Michela Cammarano, Paolo Zeppilli, Vincenzo Palmieri

“…METHODS: This study examined 511 paediatric athletes (8–18 years, 76.3% male) without known cardiovascular, renal, or endocrine diseases. All athletes underwent both HST and MET within 30 days. …”
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Effect of Early Mobilization on Respiratory and Limb Muscle Strength and Functionality of Nonintubated Patients in Critical Care: A Feasibility Trial by Maria Karoline Richtrmoc, Wagner Souza Leite, Anielle Martins Azevedo, Raissa Farias Correia, Rômulo de Aquino Coelho Lins, Wildberg Alencar Lima, Caio César Araújo Morais, Rodrigo Rios Pereira, Monique Bandeira, Carlos Eduardo Santos Rego Barros, Amina Maria Soares de Lima, Maria Glória Rodrigues-Machado, Daniella Cunha Brandão, Armèle Dornelas De Andrade, Maria Inês Remigio de Aguiar, Shirley Lima Campos

“…Maximal inspiratory and expiratory pressures (MIP and MEP), peripheral muscle strength (handgrip strength (HGS) and Medical Research Council scale (MRC-s)), and functionality (FIM, ICF-BMS, PFIT-s, and FSS-ICU scales) were evaluated at ICU admission and discharge. Results. All outcomes were significantly improved (pre vs. post values): MIP (43.93 ± 21.95 vs. 54.12 ± 21.68 cmH2O; P<0.001), MEP (50.32 ± 28.65 vs. 60.30 ± 21.23; P=0.002), HGS (25.5 (9.58) vs. 27.5 (9.48); P=0.046), MRC-s (58.52 ± 2.84 vs. 59.47 ± 1.81; P=0.023), FIM (54.4 ± 22.79 vs. 69.48 ± 12.74), ICF-BMS (28.63 ± 16.19 vs. 14.03 ± 11.15), PFIT-s (9.55 ± 2.34 vs. 11.18 ± 1.32) (P<0.001), and FSS-ICU (28.7 ± 9.1 vs. 32.6 ± 5.0; P=0.001). …”
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Derivation and validation of a clinical predictive model for longer duration diarrhea among pediatric patients in Kenya using machine learning algorithms by Billy Ogwel, Vincent H. Mzazi, Alex O. Awuor, Caleb Okonji, Raphael O. Anyango, Caren Oreso, John B. Ochieng, Stephen Munga, Dilruba Nasrin, Kirkby D. Tickell, Patricia B. Pavlinac, Karen L. Kotloff, Richard Omore

“…The following variables were associated with LDD in decreasing order: pre-enrolment diarrhea days (55.1%), modified Vesikari score(18.2%), age group (10.7%), vomit days (8.8%), respiratory rate (6.5%), vomiting (6.4%), vomit frequency (6.2%), rotavirus vaccination (6.1%), skin pinch (2.4%) and stool frequency (2.4%). While all models showed good prediction capability, the random forest model achieved the best performance (AUC [95% Confidence Interval]: 83.0 [78.6–87.5] and 71.0 [62.5–79.4]) on the development and temporal validation datasets, respectively. …”
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The association of RBP4 with chronic kidney diseases in southern Chinese population by Tong Chen, Tong Chen, Tong Chen, Yu Liu, Yu Liu, Shiquan Wu, Siyu Long, Ling Feng, Wenqian Lu, Wenya Chen, Guoai Hong, Li Zhou, Fang Wang, Yuechan Luo, Hequn Zou, Hequn Zou, Weihua Liu

“…BackgroundRetinol binding protein 4 (RBP4), as a novel adipokine, has been proven to be highly related to insulin resistance, obesity, diabetes, hypertension, hyperuricemia and other metabolic diseases, which are all risk factors for chronic kidney disease (CKD). …”
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La datation dendrochronologique du coffrage de fondation d’une pile du pont-siphon de l’Yzeron à Beaunant (Sainte-Foy-lès-Lyon, Métropole de Lyon) by François Blondel, David Baldassari

“…In the end, at least eight boards and six posts were removed, two of which were of circular cross-section found at the front of the formwork.Among the 14 timbers measured, not all show the same number of rings because of the cutting method and the age of the fir trees. …”
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Association between P2RY12 Gene Polymorphisms and IVIG Resistance in Kawasaki Patients by Zhouping Wang, Yufen Xu, Huazhong Zhou, Yanfei Wang, Wei Li, Zhaoliang Lu, Zhiyong Jiang, Xueping Gu, Hao Zheng, Lanlan Zeng, Ping Huang, Li Zhang, Xiaoqiong Gu

“…Moreover, individuals with all five protective polymorphisms experienced a significantly decreased IVIG resistance compared to that of individuals with up to three protective polymorphisms (adjusted OR = 0.27, 95% CI = 0.13–0.57, P=0.0006). …”
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Land use planning strategies for food versus non-food estate sustainable farming by D. Juhandi, D.H. Darwanto, M. Masyhuri, J.H. Mulyo, N.A. Sasongko, H.L. Susilawati, A. Meilin, T. Martini

“…The overall sustainability value of Food Eestate farming was 50.93, which was slightly higher than non-food estate  score of 48. Improving all aspects in the third scenario is the most favorable approach for improving farming sustainability. …”
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Immunological and autonomic profile of ischemic stroke in lowlands by Nargiza T. Chekeeva, Svetalana G. Shleifer, Bolot B. Kulov, Begimai B. Kadyrova, Asel T. Jusupova, Elena V. Andrianova

“…Introduction: Ischemic stroke (IS) accounts for 80–92% of all stroke cases and is primarily associated with cardiovascular diseases and chronic cerebral ischemia. …”
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Effect of Electroacupuncture Preconditioning on Inflammatory Factors of Rabbits after Spinal Cord Ischemia-Reperfusion Injury by Mengli YAO, Xianghua CHEN, Zhaohui CHEN, Hai WANG

“…Objective:To observe the effects of electroacupuncture preconditioning on the pathological changes of spinal cord tissue and the expression of inflammatory cytokines such as interleukin-1β(IL-1β), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α), interleukin-1 receptor antagonist(IL-1Rα)after spinal cord ischemia-reperfusion injury, and to explore the protective mechanism of electroacupuncture on spinal cord ischemia-reperfusion injury in rabbits.Methods:A total of twenty-four New Zealand white rabbits were randomly divided into the sham operation group, the model group and the electroacupuncture group according to the random number table method, with eight cases in each group.The model was made by Zivin method in the model group and the electroacupuncture group, the abdominal cavity was opened after intravenous anesthesia at ear margin, the abdominal aorta was exposed and temporarily clamped, and the rabbit model of spinal cord ischemia-reperfusion injury was established after ischemia for thirty minutes.The model preparation and experimental animal treatment of the sham operation group were the same as those of the model group, however, the dissection was fully exposed without clamping the abdominal aorta.At thirty minutes before the induction of rabbit spinal cord ischemia-reperfusion model, SDZ-II electroacupuncture instrument was used to acupuncture bilateral"Xuanzhong"and"Yanglingquan"acupoints in the electroacupuncture group, intervention for thirty minutes.All rabbits were killed after intervention for twelve hours, and the L2-5 segments of spinal cord tissue were captured.HE staining method was used to observe the pathological changes of spinal cord tissues in the three groups; Immunohistochemical method was used to observe the localization and content changes of IL-1β, IL-6 and TNF-α; Enzyme-linked immunosorbent assay(ELISA)was used to detect the contents of IL-1β, IL-6, TNF-α and IL-1Rα in serum before modeling and 4, 8, 12 hours after ischemia-reperfusion.Results:①HE staining results: compared with the sham operation group, the number of neurons in spinal cord tissue in the model group decreased, the color of nucleus and cytoplasm of cells became lighter, and the boundary of nuclear membrane was not clear.In severe cases, the nucleus dissolved or even nucleolus disappeared, there were transparent areas around cells, and axons showed different degrees of degeneration such as enlargement, swelling and disappearance; compared with the model group, the number of neurons in the electroacupuncture group increased, the structure of most neurons was clear, the atrophy degree of nucleolus and nucleus was light, only a small amount of cells became deformed and necrosis, the damage degree of cells were lighter, and the density of surviving neurons increased.②Immunohistochemistry results: compared with the sham operation group, the expressions of IL-1β, IL-6 and TNF-α of spinal cord tissue in the model group were significantly increased(<italic>P</italic>&lt;0.05);compared with the model group, the contents of IL-1β, IL-6 and TNF-α in the spinal cord of rabbits in the electroacupuncture group were significantly decreased(<italic>P</italic>&lt;0.05).③ELISA results: Before modeling, there was no significant difference in the three groups(<italic>P</italic>&gt;0.05);compared with before modeling, the expressions of IL-1β, IL-6, TNF-α, IL-1Rα in serum of the three groups increased in different degrees at 4, 8 and 12 h after ischemia-reperfusion, with significantly significance(<italic>P</italic>&lt;0.05);compared with the sham operation group at the same time, the expressions of IL-1β, IL-6, TNF-α and IL-1Rα in the model group increased significantly at 4, 8 and 12 h after reperfusion(<italic>P</italic>&lt;0.05);compared with the model group at the same time, the expression of IL-1β and TNF-α in the electroacupuncture group decreased significantly at 4, 8, 12 h after reperfusion(<italic>P</italic>&lt;0.05).Conclusion:Electroacupuncture pretreatment can effectively alleviate the pathological injury of spinal cord and has a good protective effect on spinal cord ischemia-reperfusion injury, which may be related to inhibit the expression of IL-1β, IL-6 and TNF-α and promote the expression of IL-1Rα.…”
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Nine draft genome sequences of Claviceps purpurea s.lat., including C. arundinis, C. humidiphila, and C. cf. spartinae, pseudomolecules for the pitch canker pathogen Fusarium circi... by Brenda D. Wingfield, Miao Liu, Hai D. T. Nguyen, Frances A. Lane, Seamus W. Morgan, Lieschen De Vos, P. Markus Wilken, Tuan A. Duong, Janneke Aylward, Martin P. A. Coetzee, Kasia Dadej, Z. Wilhelm De Beer, Wendy Findlay, Minette Havenga, Miroslav Kolařík, Jim G. Menzies, Kershney Naidoo, Olivia Pochopski, Parivash Shoukouhi, Quentin C. Santana, Keith A. Seifert, Nicole Soal, Emma T. Steenkamp, Catherine T. Tatham, Margriet A. van der Nest, Michael J. Wingfield

“…The draft genomes of Davidsoniella eucalypti, Quambalaria eucalypti and Teratosphaeria destructans, all three important eucalyptus pathogens, are presented. …”
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Electrically reconfigurable surface acoustic wave phase shifters based on ZnO TFTs on LiNbO3 substrate by Yi Zhang, Zilong Xiong, Lewei He, Yang Jiang, Chenkai Deng, Fangzhou Du, Kangyao Wen, Chuying Tang, Qiaoyu Hu, Mujun Li, Xiaohui Wang, Wenhui Wang, Han Wang, Qing Wang, Hongyu Yu, Zhongrui Wang

“…However, current acoustoelectric devices suffer from limited tunability, intricate heterogeneous structures, and complex manufacturing processes, all of which impede their practical applications. …”
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The impact of different exercise modalities on chronic kidney disease: an umbrella review of meta-analyses by Hugo L. Correa, Hugo L. Correa, Thiago S. Rosa, Thiago S. Rosa, Rafael L. Santos, Vitoria M. Mestrinho, Thaís S. Aquino, Weberth O. Santos, Rodrigo P. Neves, Lysleine A. Deus, Andrea L. Reis, Jessica M. Barbosa, Thais B. Araujo, Ruchama Verhoeff, Karim Yatim, Daniel Mendes, Roberto C. Manfro, Roberto C. Manfro, Thiago J. Borges, Leonardo V. Riella

“…Combined training showed a consistent benefit in psychosocial domains (main effect: −7.3; 95% CI: −9.31 to −53). All exercise modalities significantly improve functional performance, except isometric training, which impacted just fistula maturation (main effect: 0.84; 95% CI: 0.5–1.2).ConclusionExercise emerges as a potential non-pharmacological therapy for CKD patients. …”
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Effect of multispecies swards on ruminal fermentation, methane emission and potential for climate care cattle farming − an in vitro study by M.U. Hassan, P. Sidoruk, D. Lechniak, M. Szumacher-Strabel, J. Bocianowski, S. Ślusarczyk, P.R. Hargreaves, D. Ruska, A. Dorbe, Dz. Kreismane, K. Klumpp, J. Bloor, R.M. Rees, A. Kuipers, P. Galama, Z. Váradyová, K. Čobanová, A. Cieślak

“…Additionally, the total protozoal and methanogen counts were mostly reduced by the PLA+RC blend (P < 0.01) among all blends investigated. In conclusion, the Tonic plantain and red clover blend (PLA+RC) cultivated without fertilisers have the potential to be utilised as a sustainable alternative feed source for climate-friendly cattle production, aligning with the aims of the European Climate Care Cattle Farming project.…”
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Molecular Epidemiological Characteristics of blaIMP-4-Carrying Klebsiella pneumoniae ST-11 in Hospitalized Patients by Xue YE, Zhang D, Du S, Chen D, Liu S, Peng T, Li C, Zhang J, Wang X

“…The mortality rate was 17.7% (36/203). All 203 strains were confirmed as carbapenemases -producing strains. …”
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NaHS alleviates neuropathic pain in mice by inhibiting IL-17-mediated dopamine (DA) neuron necroptosis in the VTA by Jun Wang, Nan Zhang, Hong-Zheng Liu, Jin-Liang Wang, Yong-Bo Zhang, Dong-Dong Su, Li-Min Zhang, Bao-Dong Li, Hui-Tao Miao, Jun Miao

“…Results: In mice exposed to CCI, there was a significant decrease in dopamine neurons, a reduction in MWT and TWL, decreased expression of tyrosine hydroxylase (TH) protein and TH mRNA and an increase in VTA firing rate and MLKL colocalization with DA neurons (all p < 0.05). However, treatment with NaHS remarkably restored these changes. …”
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Expression profile of FGF23, alpha klotho, microRNA-126, and wnt signaling pathway gene polymorphism in patients with acute or chronic kidney diseases: relation to dialysis require... by Mohammed H. Hassan, Tahia H. Saleem, Ahmed Alamir Mahmoud Abdallah, Marwa Abdelhady, Doha Abd-Elraheem Salama, Abdelrahman A. Elsaied, Abdallah Elaiw Mohammed, Abdelkader Ahmed Hashim

“…However, for klotho rs564481, all participants had CT genotype. In the CKD group compared to controls, rs9921222 SNP revealed a considerably greater frequency of mutant heterozygous CT genotype with a significantly lower wild CC genotype, P = < 0.001. …”
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Calibration and Verification of the AquaCrop Model in Simulating the Yield, Dry Matter and Water Productivity of Grain Corn (Zea mays L.) under Different Irrigation Methods and Nit... by zhaleh zarei, Hassan Heidari, Saeid Jalali Honarmand, Ali Bafkar

“…AquaCrop simulation results showed that the model was able to simulate water productivity better than yield and total biomass so the coefficient of determination (R2) related to water productivity, yield, and biomass of maize was obtained as 0.82, 0.52, and 0.54 respectively.ConclusionThe simulation of yield, dry matter, and water productivity in the calibration and verification stage was lower than the actual value in all treatments. The biggest difference between the observed and simulated values of yield, biomass and water productivity was observed in the wick treatment (first and second year). …”
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‘Des nouvelles de mon infortunée sœur’: Marie-Antoinette dans les lettres de l’archiduchesse Marie-Christine à l’empereur François by Catriona Seth

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Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis by Francesca Leonardis, Viviana De Angelis, Francesca Frisardi, Chiara Pietrafitta, Ivano Riva, Tino Martino Valetti, Valentina Broletti, Gianmariano Marchesi, Lorenza Menato, Roberto Nani, Franco Marson, Mirca Fabbris, Luca Cabrini, Sergio Colombo, Alberto Zangrillo, Carlo Coniglio, Giovanni Gordini, Lucia Stalteri, Giovanni Giuliani, Vittorio Dalmastri, Gaetano La Manna

“…We herein report five patients with similar critical pathological conditions, characterized by pneumococcal or meningococcal sepsis and treated with hemoadsorption for cytokine removal. All patients showed a progressive stabilization in hemodynamics along with a rapid and marked reduction of catecholamine dosages, a stabilization in metabolic disorders, and less-than-expected loss of extremities. …”
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