A Feasibility Randomised Controlled Trial of the New Orleans Intervention for Infant Mental Health: A Study Protocol by Rachel Pritchett, Bridie Fitzpatrick, Nicholas Watson, Richard Cotmore, Philip Wilson, Graham Bryce, Julia Donaldson, Kathleen Boyd, Charles Zeanah, John Norrie, Julie Taylor, Julie Larrieu, Martina Messow, Matt Forde, Fiona Turner, Susan Irving, Helen Minnis

“…The feasibility, reliability, and developmental appropriateness of all outcome measures are examined. Additionally, the potential for linkage with routinely collected data on health and social care and, in the future, education is explored. …”
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Clinical novel exploration of intractable fever in stroke rehabilitation: a single-center cross-sectional retrospective study by Huang Jingjie, Wu Bangqi, Qin Peng, Zhang Ziyi, Cheng Yupei, Wang Chaoran, Chen Yuyan, Bai Jing

“…Compared to patients with acute fever, those with intractable fever had higher NIHSS scores (33.3% vs. 15.5%, P < 0.05), a greater incidence of consciousness disorders (66.7% vs. 28.9%, P < 0.05), and a higher rate of tracheostomy (55.6% vs. 15.5%, P < 0.05). All patients received antibiotic treatment, and gabapentin was administered to 16 cases. …”
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plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute... by Thomas R Fanshawe, Philip J Turner, Gail N Hayward, Margaret Glogowska, Alastair D Hay, Michael Moore, Mark Lown, Christopher C Butler, Mandy Wootton, Mark H Wilcox, Jane Freeman, Nicola Kenealy, Valerie Tate, Owain Llion, Rebecca Lowe

“…Introduction Acute uncomplicated urinary tract infection (UTI) is a common condition with potentially serious sequelae that is mostly diagnosed and managed in primary care settings. Around half of all women have a UTI in their lifetime, and a quarter experience an infection caused by organisms resistant to more than one antibiotic. …”
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Hepatoprotection and Phytochemistry of the Vietnamese Herbs Cleome chelidonii and Cleome viscosa Stems by Nhat Minh Phan, Thi Hong Tuoi Do, Le Thanh Tuyen Nguyen, Trong Tuan Nguyen, Quoc Luan Ngo, Trong Duc Tran, Quan Hien Nguyen, Bui Linh Chi Huynh, Diep Xuan Ky Nguyen, Trong Dat Bui, Dinh Tri Mai, Tan Phat Nguyen

“…The study aims to determine the hepatoprotective effect of n-hexane, ethyl acetate, and methanol extracts of the leaves and stems of two Cleome species against carbon tetrachloride- (CCl4-) induced liver toxicity both in vitro using human hepatoma (HepG2) cells and in vivo in rats as well as the hepatoprotective property of all isolated compounds on HepG2. After 72 h of treatment, at the concentrations of 25, 50, and 100 μg/mL, the methanol of C. chelidonii stems (CCSM) ranged from 18.6% to 20.8%, whereas the methanol of C. chelidonii stems (CVSM) increased from 12.3% to 17.2% cell viability. …”
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Significance of Biogenetic Markers in Giant Cell Tumor Differentiation and Prognosis: A Narrative Review by Muhammad Taqi, Haseeb ul Rasool, Mobeen Zaka Haider, Munjed Al Muderis

“…It accounts for only 5% of all bony tumors. Early diagnosis, and follow-up for recurrence is often difficult due to a lack of biogenetic markers. …”
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Illuminating a biologics development challenge: systematic characterization of CHO cell-derived hydrolases identified in monoclonal antibody formulations by Melanie Maier, Linus Weiß, Nikolas Zeh, Valerie Schmieder-Todtenhaupt, Alireza Dehghani, Marius Nicolaus Felix, Daniel Heinzelmann, Benjamin Lindner, Moritz Schmidt, Joey Studts, Patrick Schulz, Bernd Reisinger, Kerstin Otte, Matthias Franzreb, Daniel Lakatos, Simon Fischer

“…Applying a PS degradation assay, we found nine mostly secreted, PS-active hydrolases with varying hydrolytic activity. All active hydrolases showed a serine-histidine-aspartate/glutamate catalytical triad. …”
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Comparative-effectiveness research of COVID-19 treatment: a rapid scoping review by Sharon E Straus, Jesmin Antony, Andrea C Tricco, Rachel Warren, Erin Macdonald, Ba Pham, Milan Patel, Fatemeh Yazdi, Amruta Radhakrishnan, Marco Ghassemi, Patricia Rios, Chantal Williams, Naveeta Ramkissoon, Matthew P Muller, Nazia Darvesh, Gordon V Cormack, Maura R Grossman, Melissa Kampman, Reid Robson

“…We aim to provide an overview of the characteristics of studies evaluating COVID-19 treatment.Design Rapid scoping reviewData sources Medline, Embase and biorxiv/medrxiv from inception to 15 May 2021.Setting Hospital and community care.Participants COVID-19 patients of all ages.Interventions COVID-19 treatment.Results The literature search identified 616 relevant primary studies of which 188 were randomised controlled trials and 299 relevant evidence syntheses. …”
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Identifikasi Emosi Manusia Berdasarkan Ucapan Menggunakan Metode Ekstraksi Ciri LPC dan Metode Euclidean Distance by Siti Helmiyah, Imam Riadi, Rusydi Umar, Abdullah Hanif, Anton Yudhana, Abdul Fadlil

“…The use of the LPC method as feature extraction gave unfavorable results in this study because the average accuracy was only 31.67% for the identification of all emotions. Voice data used with different sentences, actors, ages, and accents can influence the recognition of emotions, therefore the extraction of features in the recognition of speech patterns of human emotions is very important. …”
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Socioeconomic indicators related to the global burden of breast cancer in women in 2020: an analysis of WHO data by Tingting XU, Ruoyu YANG, Jingjing LI, Yiying FANG

“…Correlation analysis showed that the global MIR of breast cancer in women was positively correlated with urban particulate matter (r = 0. 480) and net ODA per capita (r = 0. 516) (both P < 0. 001) and negatively correlated with physician density (r = – 0.782), pharmacist density (r = – 0.639), average core capacity score (r = – 0.635), percentage of government health expenditure (r = – 0.614), population using sanitation services (r = – 0.624), and HDI (r = – 0.900) (all P < 0.001). Multiple linear regression analysis showed that net ODA per capita had a positive effect on the female breast cancer burden (β = 0.003, 95% confidence interval [95%CI]: 0.002 – 0.007), while total female population (β = – 0.004, 95%CI: – 0.005 to – 0.003), physician density (β = – 0.007, 95%CI: – 0.008 to – 0.006), pharmacist density (β = – 0.026, 95%CI: – 0.030 to – 0.021), average core capacity score (β = – 0.005, 95%CI: – 0.006 to – 0.004), and HDI (β = – 0.873, 95%CI: – 0.906 to – 0.574) had negative effects. …”
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Clinical Evaluation of LASEK for High Myopia Correction between the Triple-A Profile and the Zyoptix Tissue Saving Profile by Min Li, Yuehui Shi, Lina Sun, Lin Liu, Chen Qu, Jun Zou

“…The changes in refraction 6 months after surgery comparing with 1 month after surgery were 0.12 ± 0.10 D in the Triple-A group and 0.13 ± 0.08 D in the TS group (P=0.56). All (100%) of the patients in the Triple-A group and 50% of the patients in the TS group had a UDVA of 20/16 at 6 months after surgery (P<0.01). …”
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Effect of Tonifying deficiency and Zhengqi porridge on immune function reconstruction in HIV/AIDS patients with Qi deficiency (补虚正气粥对艾滋病气虚型患者免疫功能重建的影响研究)... by WEI Yan (魏艳), LI shu (李树), YUAN Hongxia (袁洪霞), ZHANG Ying (张英), LIU Xiaoli (刘小丽), LIU Lingling (刘玲玲)

“…Methods Sixty (Human Immunodeficiency Virus/ Acquired Immunodeficiency Syndrome)HIV/AIDS patients admitted to the center for Disease Control and prevention in Huichuan District of Zunyi City were randomly divided into control group and treatment group by random number table. All patients received the highly active anti-retroviral therapy, and those in the treatment group were given Tonifying deficiency and Zhengqi porridge. …”
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Time Interval for Diagnosis of Tuberculosis and Related Expenditure in Selected Health Centers in Addis Ababa, Ethiopia by Ezra Shimeles, Melaku Tilahun, Tsegaye Hailu, Fikre Enquselassie, Abraham Aseffa, Alemayehu Mekonnen, Getachew Wondimagegn

“…The total combined expenditure for all the visits was estimated to be median (IQR) 172.65 birrs (12, 671). …”
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Immunogenic dying cells elicit potent anti-tumor T cell immunity against lung metastasis and tumorigenesis by Min Hu, Xinyu Meng, Tong Wang, Yifan Wang, Xiaodong Chen, Dongliang Xu, Wei He, Hongjia Zhang, Wenzheng Guo, Bo Jing, Siwei Zhang, Jianhua Xu, Beibei Sun, Xueqian Sun, Tingting Liu, Na Ni, Tongtong Zhang, Wenwen Cui, Xiaoyu Wu, Liping Xia, Feng Yao, Fang Zhang, Jing Du, Jiong Deng

“…Abstract Purpose Immune checkpoint blockades (ICBs) are promising, however they do not fit all types of tumor, such as those lack of tumor antigens. …”
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LLT1 overexpression renders allogeneic-NK resistance and facilitates the generation of enhanced universal CAR-T cells by Shuxian Zhu, Shiyu Zuo, Chuo Li, Xingjie You, Erlie Jiang, Xiaoming Feng, Yuechen Luo

“…In a humanized T-cell acute lymphoblastic leukemia (T-ALL) model, CD38 allogeneic universal CAR-T cells demonstrated superior survival rates and tumor clearance with reduced inflammatory responses. …”
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Eco-friendly sustainable farming: Enhancing summer tomato (Lycopersicon esculentum mill.) yield with jute non-woven agro textile Mulch by Nilimesh Mridha, Dipak Nayak, Ashok Yadav, Tilak Mondal, Rakesh Kr Ghosh, Manik Bhowmick, Atul Singha, D.P. Ray, B.S. Manjunatha, Avijit Das, D.B. Shakyawar, Sourav Paul, Amit Das, Santanu Mukherjee, Ravinder Kumar

“…The temperature throughout the soil depths for all mulch treatments was lower over no mulch, and for 650 GSM, it was the lowest. …”
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Evaluation of the Prognostic Value of Red Cell Distribution Width to Total Serum Calcium Ratio in Patients with Acute Pancreatitis by Tian-Yong Han, Tao Cheng, Bo-Fu Liu, Ya-Rong He, Pan Pan, Wen-Tao Yang, Qiang-Lai, Yu Cao

“…Demographic information and clinical and laboratory parameters of all enrolled patients after being admitted to ED were compared between the groups. …”
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Regarder au-delà des élections : l’historicité complexe de la participation politique dans la Libye contemporaine by Chiara Loschi, Chiara Pagano

“…However, these perspectives have been rarely applied to the analysis of post-Gaddafi Libya, where the axiomatic acquisition that a positive link exists between elections and democratic transition has obscured the potentialities of engaging into a scholarly debate encompassing all the “politics of becoming” that might be detected by looking even at those mobilisations that escape and often contest the electoral dynamic. …”
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Ginsenoside Ro prevents endothelial injury via promoting Epac1/AMPK- mediated mitochondria protection in early diabetic retinopathy by Jia Liu, Yunqi Zhang, Xiaoyu Xu, Xi Dong, Yunfeng Pan, Xiaobo Sun, Yun Luo

“…First-line therapeutic drugs are all focused on late-stage DR and have several side effects, which could not meet clinical needs. …”
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Unravelling population structure and marker trait association using SSR markers among the identified drought tolerant rice landraces (Oryza sativa L.) by Shanmugam Manju Devi, John Amalraj Joel, Muthurajan Raveendran, Ramamoorthy Pushpam, Sengalan Muthuramu, Raman Pushpa, N. Sritharan, Periyasamy Prasanna, Ramalingam Suresh

“…Variance analysis, revealing significant genetic variation among genotypes for all studied traits, indicating genetic variability. …”
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Desarrollo de la nueva guía canadiense de diseño y gestión de infraestructura vial 2011: un resumen del estado de la práctica canadiense Development of the new 2011 canadian paveme... by Susan L Tighe, Norman W. McLeod, Marta Juhasz

“…The project is a pooled fund study being sponsored by over twenty Canadian public agencies including all ten provincial Canadian Departments of Transportation, several major Canadian cities, several industry associations and the federal government. …”
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