Genetic diversity of Plasmodium falciparum reticulocyte binding protein homologue-5, which is a potential malaria vaccine candidate: baseline data from areas of varying malaria end... by Angelina J. Kisambale, Dativa Pereus, Salehe S. Mandai, Beatus M. Lyimo, Catherine Bakari, Gervas A. Chacha, Ruth B. Mbwambo, Ramadhan Moshi, Daniel A. Petro, Daniel P. Challe, Misago D. Seth, Rashid A. Madebe, Rule Budodo, Sijenunu Aaron, Daniel Mbwambo, Abdallah Lusasi, Stella Kajange, Samwel Lazaro, Ntuli Kapologwe, Celine I. Mandara, Deus S. Ishengoma

“…Negative Tajima's D values were observed among the parasite populations in all the study sites. Conclusion Low levels of polymorphism in the pfrh5 gene were observed based on low nucleotide and haplotype diversity, a lack of population structure and negative Tajima’s D values. …”
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Complete mitochondrial genomes of Culicoides brevitarsis and Culicoides imicola biting midge vectors of Bluetongue Virus by Khandaker Asif Ahmed, Anjana Karawita, Melissa J. Klein, Luana Fiorella Mincarelli, Barbara Secondini, Giuseppe Satta, Massimo Ancora, Cipriano Foxi, Marco Di Domenico, Michela Quaglia, Maria Goffredo, Alessio Lorusso, Cesare Cammà, Leon Court, Rahul V. Rane, Tom K. Walsh, Prasad N. Paradkar, Debbie Eagles, Gunjan Pandey, Christopher M. Hardy

“…The genome sizes are 17,100 bp and 17,031 bp, respectively, all comprising 37 genes, including 13 protein, 22 tRNA, two rRNA coding genes, and one non-coding AT rich control region. …”
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A first evaluation of the efficacy of minibeam radiation therapy combined with an immune check point inhibitor in a model of glioma-bearing rats by Lorea Iturri, Emmanuel Jouglar, Cristèle Gilbert, Julie Espenon, Marjorie Juchaux, Yolanda Prezado

“…The goal was to assess the gain in survival of animals treated with MBRT, MBRT plus an immune check point inhibitor (ICI) versus conventional RT (CRT) or ICI alone. All treatments (ICI alone, CRT, CRT + ICI, MBRT and MBRT + ICI) increased survival with respect to the non-irradiated controls. …”
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Endoscopic Sphincterotomy before Fully Covered Metal Stent Placement Is Not Required for Distal Malignant Biliary Stricture due to a Pancreatic Head Tumor by Kazunari Nakahara, Yosuke Michikawa, Ryo Morita, Keigo Suetani, Nozomi Morita, Junya Sato, Kensuke Tsuji, Hiroki Ikeda, Kotaro Matsunaga, Tsunamasa Watanabe, Nobuyuki Matsumoto, Shinjiro Kobayashi, Takehito Otsubo, Fumio Itoh

“…The incidence of hyperamylasemia in the EST and non-EST groups was 12.5% and 13.9%, respectively (P=0.85). The incidence of all AEs in the EST and non-EST groups was 15.6% (pancreatitis: 1, cholecystitis: 2, and stent migration: 2) and 13.9% (cholecystitis: 3, stent migration: 2), respectively (P=0.89). …”
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Impact of Cordyceps sinensis on coronary computed tomography angiography image quality and renal function in a beagle model of renal impairment by Peiji Song, Peiji Song, Kun Li, Xiaodie Xu, Guifeng Zhang, Zengkun Wang, Linbing Sun, Zekai Zhao, Ting Li, Ximing Wang, Zhangyong Xia, Zhangyong Xia, Zhangyong Xia, Zhangyong Xia

“…Laboratory renal function markers were measured multiple times before and after the intervention, and their correlation with fMRI parameters was analyzed.ResultsCCTA imaging revealed that the CT values of the major coronary artery branches in all groups met the international diagnostic criteria for coronary arteries. …”
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Survei Penelitian Metode Kecerdasan Buatan untuk Mendeteksi Ancaman Teknologi Serangan Siber by Eza Yolanda Fitria, Kusprasapta Mutijarsa

“…A total of 44 reviewed survey papers were published between 2018 and 2023. Of all these, 30 papers discuss machine learning and deep learning techniques. …”
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Implementasi Protokol Routing HEED pada Wireless Sensor Network dengan Perangkat Berbasis Modul Komunikasi nRF24L01 by Giservin Tifira Zain, Rakhmadhany Primananda, Agung Setia Budi

“…The implementation is carried out on a small-scale network where the sensor nodes only amount to 8 and the distance between is not far away making each node still reach all nodes on the network. With the limitations of the nRF24L01, cluster formation is quite time-consuming and energy-consuming due to the need for calculating node costs and synchronizing time between nodes. …”
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Effect of Traditional Chinese Medicine nursing intervention on vertigo in patients with acute stroke (急性中风患者眩晕中医护理干预效果观察) by FU Jingna (付景娜), YANG Junhang (杨俊行), GENG Qingwen (耿庆文), CHEN Cheng (陈程), SONG Ying (宋颖), ZHAO Yazheng (赵亚争), SUN Yi (孙祎)

“…Objective To observe the effect of Traditional Chinese Medicine (TCM)nursing intervention on vertigo in patients with acute stroke Methods Totally 80 acute stroke patients with vertigo were randomly divided into the observation group and control group, with 40 cases in each group. All patients received routine medication treatment and rehabilitation care. …”
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Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

“…Despite these significant clinical observations, investigation into cerebrovascular dysfunction and neuropathology in MFS remains limited.MethodsUsing 6M-control (C57BL/6) and 6M-MFS (Fbn1C1041G/+) and healthy 12M-control male and female mice, we test the hypothesis that abnormal Fbn1 protein expression is associated with altered cerebral microvascular density, BBB permeability, and neuroinflammation in the PCA-perfused hippocampus, all indicative of a pre-mature aging brain phenotype. …”
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Long-term safety of tofacitinib up to 9.5 years: a comprehensive integrated analysis of the rheumatoid arthritis clinical development programme by Peter Nash, Yoshiya Tanaka, Kevin L Winthrop, Eun Bong Lee, Xavier Mariette, Jeffrey R Curtis, Kenneth Kwok, Connie Chen, Pinaki Biswas, Lisy Wang, Christina Charles-Schoeman, Ann Madsen, Stanley B Cohen, Andrea Shapiro, Jürgen Wollenhaupt

“…IRs (95% CI) for serious AEs, serious infections, herpes zoster (all), opportunistic infections (excluding tuberculosis [TB]) and TB were 9.0 (8.6 to 9.4), 2.5 (2.3 to 2.7), 3.6 (3.4 to 3.9), 0.4 (0.3 to 0.5) and 0.2 (0.1 to 0.2), respectively. …”
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Characteristics of the monkeypox virus isolate obtained from the first patient in Russia and its sensitivity to 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo-[3.2.2.0... by Alena S. Ovchinnikova, Dmitrii A. Odnoshevsky, Alexey S. Kabanov, Sergey A. Bodnev, Oleg V. Pyankov, Oksana P. Os'kina, Maria V. Sivay, Andrey V. Bespalov, Tatyana V. Tregubchak, Larisa N. Shishkina, Oleg S. Taranov, Vladimir V. Zolin, Artemiy A. Sergeev, Alexander P. Agafonov

“…A diagnostic study of the biological samples of a patient who returned from a tourist trip to European countries with complaints of skin rashes all over the body revealed MPXV DNA. A new strain of MPXV was isolated from vesicles in Vero E6 cells, and the genomic sequence MPXV-pustule S45 was assembled using high-throughput parallel sequencing (NGS). …”
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Changes in alcohol consumption among Belgian adults participating in the internet-based one-month-abstinence campaign ‘Tournée Minérale’ by Annelies Thienpondt, Jelle Van Cauwenberg, Joris Van Damme, Gera E. Nagelhout, Benedicte Deforche

“…Repeated measures ANCOVAs were used to examine changes over time in alcohol consumption (log transformed due to skewness) and determinants among TMC participants (n = 8,730, 48.4 ± 12.9 years old, 37.4% males) who filled in all three measurements. Moderation effects were assessed for age, sex, education level, successfully refraining from alcohol during TMC, risk drinking, drinking levels and binge drinking at baseline. …”
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Depression screening using patient-targeted feedback in general practices: study protocol of the German multicentre GET.FEEDBACK.GP randomised controlled trial by Joachim Szecsenyi, Hans-Helmut König, Karl Wegscheider, Martin Härter, Bernd Löwe, Antonius Schneider, Martin Scherer, Jürgen Gallinat, Antonia Zapf, Sebastian Kohlmann, Marco Lehmann, Marion Eisele, Lea-Elena Braunschneider, Gabriella Marx, Stefanie Joos, Gaby Resmark, Christine Allwang, Christoph Nikendei, Sven Schulz, Katja Brenk-Franz

“…According to a statistical analysis plan, the primary endpoint of all randomised patients will be analysed regarding the intention-to-treat principle.Ethics and dissemination The Ethics Committee of the Hamburg Medical Association approved the study. …”
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Evaluation of the efficiency of Russian universities: Do we need to change the paradigm? by E. V. Romanov

“…It was found that the majority of “peripheral” technical universities have an “innate” sign of “inefficiency” - the average USE score of incoming applicants is less than 60, which was recorded during almost all monitoring measurements in 2013-2019. This leads to a zero rating on one of the indicators of the efficiency of educational activities and creates a false idea of the potential of organisations since the employment rates of graduates in the vast majority of universities in this category are above the threshold values. …”
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Pengaruh Hemodialisis terhadap Urea Reduction Ratio pada Pasien Penyakit Ginjal Kronik Stadium V di RSUP Dr. M. Djamil Padang by Wahyuni Armezya, Ellyza Nasrul, Elizabet Bahar

“…<br clear="all" /><p><strong>Abstrak</strong></p><p> Pravelensi pasien penyakit ginjal kronik stadium V yang mendapat terapi hemodialisis terus meningkat di dunia. …”
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Whole-genome sequencing identifies novel loci for keratoconus and facilitates risk stratification in a Han Chinese population by Yinghao Yao, Xingyong Li, Lan Wu, Jia Zhang, Yuanyuan Gui, Xiangyi Yu, Yang Zhou, Xuefei Li, Xinyu Liu, Shilai Xing, Gang An, Zhenlin Du, Hui Liu, Shasha Li, Xiaoguang Yu, Myopia Associated Genetics Intervention and Consortiums, Hua Chen, Jianzhong Su, Shihao Chen

“…We detected three common variants reaching genome-wide significance (P ≤ 5 × 10−8), all of which are novel to KC. Our study validated three well known predisposition loci, COL5A1, EIF3A and FNDC3B. …”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

“…They are advised to wear their study shoes for all planned sports and exercise-based activities over the subsequent 3 months and are also advised that they may wear them as much as desired at other times. …”
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Economic and environmental sustainability of agriculture production at the crop level by A.Z. Bi, K.B. Umesh, B. Md Abdul, D. Sivakumar, P. Srikanth

“…To address the problem of unsustainable production practices, accounting for them by bringing all aspects of sustainability under a single umbrella is paramount. …”
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Barriers and drivers to COVID-19 protective behaviours of forcibly displaced myanmar nationals (FDMN)/ rohingya refugees in Cox's bazar, Bangladesh: A scoping review by Sarah Reda, Zarah Yusuf, Basel Karo, Balwinder Singh Chawla, Andreas Jansen, Saskia Lange, Jorge Martinez, Emily Dorothee Meyer, Julia Neufeind, Aarti Shrikrishana Singh, Elisa Wulkotte, Cath Jackson

“…Barriers and drivers to these behaviors spanned all four COM factors reflecting both individual and environmental influences. …”
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A CO₂–Δ¹⁴CO₂ inversion setup for estimating European fossil CO₂ emissions by C. Gómez-Ortiz, G. Monteil, G. Monteil, S. Basu, S. Basu, M. Scholze

“…In a second set of experiments using realistic prior fluxes, we find that in addition to retrieving the time series of the optimized fluxes, we are able to recover the true regional fossil <span class="inline-formula">CO₂</span> budget in western/central Europe by 95 % and in Germany by 97 %. In all experiments, regions with low sampling coverage, such as southern Europe and the British Isles, show poorly resolved posterior fossil <span class="inline-formula">CO₂</span> emissions. …”
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