Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling by Adolf Koudelka, Gregory J. Buchan, Veronika Cechova, James P. O’Brien, Emily R. Stevenson, Crystal E. Uvalle, Heng Liu, Steven R. Woodcock, Steven J. Mullett, Cheng Zhang, Bruce A. Freeman, Stacy L. Gelhaus

“…Despite the expression of catalytically active enzymes required for LXA4 synthesis, both LXA4 and its 15-oxo-LXA4 metabolite were undetectable in all conditions. Moreover, synthetic LXA4 and the membrane-permeable 15-oxo-LXA4 methyl ester, which rapidly de-esterified to 15-oxo-LXA4, displayed no ligand activity for the putative LXA4 receptor FPR2. …”
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Specimen oriented intraoperative margin assessment in oral cavity and oropharyngeal squamous cell carcinoma by P. Horwich, C. MacKay, M. Bullock, S. M. Taylor, R. Hart, J. Trites, L. Geldenhuys, B. Williams, M. H. Rigby

“…Study design Retrospective case series and subsequent prospective cohort study Setting Tertiary care academic teaching hospital Subjects and methods Retrospective case series of all institutional T1-T2 OCSCC or OPSCC treated with primary surgery between January 1st 2009 – December 31st 2014. …”
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Population genetic analysis of clinical Mycobacterium abscessus complex strains in China by Xiangchen Li, Xiangchen Li, Yelei Zhu, Yewei Lu, Kunyang Wu, Yang Che, Xiaomeng Wang, Weixin Wang, Junli Gao, Junshun Gao, Zhengwei Liu, Zhengwei Liu, Zhuxian Zhou

“…Mobile genetic elements (MGEs), such as prophages and genomic islands, were prevalent across all genomes. 139 to 151 virulence factors (VFs) were identified per genome, with distinct accessory VFs in MabA and MabM affecting immune modulation and metabolism. …”
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Effects of cage size on the natural behavior, serum parameters, production performance and hypothalamic mRNA expression profiles of laying hens by Yi Wan, Ruiyu Ma, Renrong Qi, Dawei Jiang, Helong Guan, Wei Liu, Junying Li, Yan Li, Kai Zhan

“…The stocking density remained consistent across all groups throughout the experimental period. Behavioral expression was evaluated through observation of only six birds per group on a weekly basis. …”
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The growth performance and physiological status of comet goldfish Carassius auratus in aquascape with different aquatic plant species by Rafiatun Indriani, Yani Hadiroseyani, Iis Diatin, Media Fitri Isma Nugraha

“…The liver superoxide dismutase level of comet goldfish obtained a significant difference value between fish reared with aquatic plants and without aquatic plants, while the malondialdehyde value of all treatments was insignificantly difference. Also, the increased of total erythrocytes, total leucocytes, hemoglobin, and hematocrit were found on comet goldfish reared with aquatic plants. …”
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Delineation of reduced CTV2 on the basis of the characteristics and distribution of cervical lymph node metastasis in nasopharyngeal carcinoma by Zhiqiang Wang, Yi Yang, Chunlei Ge, Rui Tian, Sheng Cheng, Jingyu Gao, Yan Wang, Qi Yue, Zhiwei Wang, Qingqing He, Yuchuan Xu, Yan Li, Xudong Feng, Yanli Yang, Yong Zhang

“…Using MIM software, we integrated all patients’ lymph node images onto the template CT images and conducted an in-depth analysis of their distribution characteristics and metastatic patterns. …”
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Risk factors for delayed gastric emptying after pancreatoduodenectomy: a 10-year retrospective study by Carlos Jiménez-Romero, Agustín de Juan Lerma, Alberto Marcacuzco Quinto, Oscar Caso Maestro, Laura Alonso Murillo, Paula Rioja Conde, Iago Justo Alonso

“…However, the pathophysiology of DGE remains unclear.Methods This is a retrospective study of patients who underwent PD for pancreatic or periampullary tumours. All these patients were operated between January 2012 and February 2023. …”
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Multicentre adaptive randomised trial of GvHD prophylaxis following unrelated donor stem cell transplantation comparing Thymoglobulin versus calcineurin inhibitor-based or sirolimu... by Simon Gates, Matthew Collin, Victoria Potter, Rebecca Bishop, Ronjon Chakraverty, Kavita Raj, Adrian Bloor, Andrea Hodgkinson, Jeff Davies, Emma Kempshall, Fiona Dignan, Ram Malladi, Siobhan Smith, Charlotte Gaskell, Gabrielle Smith

“…The Medicines and Healthcare products Regulatory Authority also approved all protocol versions. The results of this trial will be disseminated through national and international presentations and peer-reviewed publications.Trial registration number EudraCT Number: 2019-002419-24.ISRCTN Number: 50290131.…”
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The Role of Hibiscus sabdariffa L. (Roselle) in Maintenance of Ex Vivo Murine Bone Marrow-Derived Hematopoietic Stem Cells by Zariyantey Abdul Hamid, Winnie Hii Lin Lin, Basma Jibril Abdalla, Ong Bee Yuen, Elda Surhaida Latif, Jamaludin Mohamed, Nor Fadilah Rajab, Chow Paik Wah, Muhd Khairul Akmal Wak Harto, Siti Balkis Budin

“…Roselle enhanced the survival (P<0.05) of BMCs at 500 and 1000 ng/mL, increased survival of Sca-1+ cells (HSCs) at 500 ng/mL, and maintained HSCs phenotype as shown from nonremarkable changes of surface marker antigen (Sca-1) expression in all experimental groups. Roselle increased (P<0.05) the GSH level and SOD activity but the level of reactive oxygen species (ROS) was unaffected. …”
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Determinants of Dropout From a Virtual Agent–Based App for Insomnia Management in a Self-Selected Sample of Users With Insomnia Symptoms: Longitudinal Study by María Montserrat Sanchez Ortuño, Florian Pecune, Julien Coelho, Jean Arthur Micoulaud-Franchi, Nathalie Salles, Marc Auriacombe, Fuschia Serre, Yannick Levavasseur, Etienne De Sevin, Patricia Sagaspe, Pierre Philip

“…The primary outcome was a binary variable: having dropped out after completing the screening assessment (early dropout) or having completed all the treatment phases (n=551). Multivariable logistic regression analysis was used to identify predictors of dropout among a set of sociodemographic, clinical, and sleep diary variables, and users’ perceptions of the treatment program, collected during the screening interview. …”
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Association between migraine severity and sleep quality: a nationwide cross-sectional study by Nura A. Almansour, Nura A. Almansour, Seham S. Alsalamah, Seham S. Alsalamah, Razan S. Alsubaie, Razan S. Alsubaie, Nada N. Alshathri, Nada N. Alshathri, Yasmeen A. Alhedyan, Yasmeen A. Alhedyan, Faisal Y. Althekair’s, Faisal Y. Althekair’s, Faisal Y. Althekair’s

“…This study therefore aimed to determine the association between sleep quality and migraine severity.MethodsA comparative cross-sectional study was conducted with 1,399 participants across all regions of Saudi Arabia from August to October 2023 using standardized questionnaires. …”
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Pemanfaatan Fuzzy Logic dan Hill Climbing untuk Optimasi Pengelolaan Tempat Pengolahan Sampah Reduce-Reuse-Recycle (TPS 3R) pada Dinas Lingkungan Hidup (DLH) DKI Jakarta by Ramadana Arbi, Meinarini Catur Utami, Qurrotul Aini

“…Abstract DLH DKI Jakarta is a Government Institution that responsible for waste management about 1125 temporary waste shelters (TPS) spread across 5 Regions in DKI Jakarta; i.e South Jakarta, East Jakarta, West Jakarta, North Jakarta, and Central Jakarta. All those TPS’s are including some of 3R TPS (Reduce, Reuse, and Recycle).    …”
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Malnutrisi Energi Protein Berat: Laporan Kasus by Peter Prayogo Hsieh, Putri Dariyanti Wijaya, Putri Aziana, Prahara Wahyu Purnomo, Sitti Radhiah

“…Understanding children’s nutrition is essential to all healthcare workers in order to decrease the incidence of malnutrition in Indonesia. …”
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An atmospheric correction method for Himawari-8 imagery based on a multi-layer stacking algorithm by Menghui Wang, Donglin Fan, Hongchang He, You Zeng, Bolin Fu, Tianlong Liang, Xinyue Zhang, Wenhan Hu

“…The results demonstrate that the MSM AC exhibits strong adaptability to the optical characteristics of complex water bodies, achieving low MedAE values across all types of optically complex water bodies. Furthermore, the spatial mapping of MSM-corrected reflectance exhibits a high agreement with the MODIS and Himawari-8 Advanced Himawari Imagery water-leaving reflectance products, further confirming its superiority. …”
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Gambaran Faktor Risiko dan Tipe Stroke pada Pasien Rawat Inap di Bagian Penyakit Dalam RSUD Kabupaten Solok Selatan Periode 1 Januari 2010 - 31 Juni 2012 by Cintya Agreayu Dinata, Yuliarni Safrita Safrita, Susila Sastri

“…The data including age, gender, blood pressure, glucose level, lipid profile when the first patient in the hospital, and jobs. The samples were all stroke patients who had been treat in the Department of Internal Medicine of South Solok hospital in the period from January 1st 2010 until June 31th 2012 that meet the inclusion criteria.The results: The results showed the highest proportion of strokes were ischemic stroke (61.46%), women (54.17%) aged&gt; 50 years (81.25%) who work as housewives (43.75%). …”
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The Timing of Infarction Pain in Patients with Acute Myocardial Infarction after Previous Revascularization by Predrag M. Mitrovic, Branislav Stefanovic, Zorana Vasiljevic, Mina Radovanovic, Nebojsa Radovanovic, Gordana Krljanac, Dubravka Rajic, Predrag Erceg, Vladan Vukcevic, Ivana Nedeljkovic, Miodrag Ostojic

“…The subgroups with specific clinical characteristics exhibited different patterns that determined these peaks in all populations. In patients older than 70 years of age, in both sexes, in smokers, diabetics, in patients with hypertension, in those undergoing beta-blocker therapy, and in patients without previous angina, two nearly equal peaks were observed, with higher evening peaks, except in those patients with hypertension and without angina. …”
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Nonlinear optical response of thermally stable perovskite for near-infrared optical modulator by Jiang Wang, Liang Xie, Jingjing Liu, Yuxuan Sun, Jinglong Xu, Jiacheng Li, Zhongying Zhang, Chengbing Qin, Liantuan Xiao, Guofeng Zhang, Yonggang Wang, Zhichun Yang, Guanghua Cheng

“…Metal halide perovskite has generated significant attention due to its high optical absorption coefficient, the tunability of bandgap, and its solution processing properties, all of which have led to a range of applications including solar cells, photodetectors, light-emitting diodes and lasers. …”
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Study on the infection characteristics and pathogenesis of duck circovirus 1 in Cherry Valley meat ducks by Hanqing Li, Guige Xu, Hui Yan, Lei Bei, Mingrui Zhao, Ruihua Zhang, Yu Meng, Yanli Zhu, Liangmeng Wei, Zhijing Xie, Shijin Jiang

“…DuCV-1 was detectable in all organs and caused multiple local lesions. The virus was initially detected in the liver and the organ with the highest viral titer was the thymus. …”
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Inflammatory Markers and Severity in COVID-19 Patients with Clostridioides Difficile Co-Infection: A Retrospective Analysis Including Subgroups with Diabetes, Cancer, and Elderly by Teodor Cerbulescu, Flavia Ignuta, Uma Shailendri Rayudu, Maliha Afra, Ovidiu Rosca, Adrian Vlad, Stana Loredana

“…CDI-positive patients experienced increased ICU admission (38.8% vs. 20.5%), mechanical ventilation (24.5% vs. 12.9%), and mortality (22.4% vs. 10.6%, all <i>p</i> < 0.05). Subgroup analyses revealed more pronounced inflammatory derangements and worse outcomes in elderly, diabetic, and cancer patients with CDI. …”
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High-grade liver injury: outcomes with a trauma surgery–liver surgery collaborative approach by J Wallis Marsh, Abhinav Humar, Jason L Sperry, David A Geller, Deepika Mohan, Timothy R Billiar, Juan Carlos Puyana, Brian Zuckerbraun, Joshua B Brown, Matthew D Neal, Matthew R Rosengart, David Newhouse, Christine Leeper, Andrew B Peitzman, Raquel Forsythe, Rafael G Ramos-Jimenez, Andrew-Paul Deeb, Evelyn I Truong, Sowmya Narayanan, Louis Alarcon, Graciela M Bauza, Vaishali Dixit Schuchert, Gregory Watson, Amit D Tevar

“…The primary outcome was 30-day mortality.Results Our institution treated 179 patients with HGLI (78% blunt, 22% penetrating); 122 grade IV (68%) and 57 grade V (32%) injuries. All abdominal gunshot wounds and 49% of blunt injuries underwent initial OM; 51% of blunt injuries were managed initially by NOM. …”
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