Deciphering the Differences Between Epstein–Barr Virus‐Associated and Negative Gastric Cancer in the Prospect of CDKN2A Genomic Alterations and Lymphoid Infiltration by Fuda Xie, Bonan Chen, Yang Lyu, Peiyao Yu, Canbin Fang, Kam Tong Leung, Shouyu Wang, Dazhi Xu, Jun Yu, Kwok Wai Lo, Ka Fai To, Wei Kang

“…Results CDKN2A genestayed intact in all EBV‐associated GC cases. Meanwhile, CDKN2A deletion (8.43% cases) was exclusive to EBV‐negative GC cases. …”
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Identification of Staphylococcus aureus, Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii from Raman spectra by Artificial Intelligen... by Yu-Tzu Lin, Hsiu-Hsien Lin, Chih-Hao Chen, Kun-Hao Tseng, Pang-Chien Hsu, Ya-Lun Wu, Wei-Cheng Chang, Nai-Shun Liao, Yi-Fan Chou, Chun-Yi Hsu, Yu-Hui Liao, Mao-Wang Ho, Shih-Sheng Chang, Po-Ren Hsueh, Der-Yang Cho

“…At the species level, S. aureus, E. faecium, K. pneumoniae, P. aeruginosa, and A. baumannii were identified with high accuracy, ranging from 94.76 % to 96.88 %, with all species achieving an AUC of 0.99. Conclusions: Validation with a large number of clinical isolates demonstrated Raman spectroscopy combined with ML excels in identification of five bacterial species associated with multidrug resistance. …”
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A Systematic Review on Poisoned Patients as Potential Organ Donors by Kattamreddy Ananth Rupesh, Anirudh Suseel Nalumaru, Mohit Kumar Moses Thathapudi, Omkarnath Sivarchaka, Deekshitha Alla

“…While there’s no single answer to all questions posed by transplant surgeons regarding poisoned patients, it is evident that harvesting organs from poisoned/intoxicated donors is no longer experimental but founded on robust scientific evidence and ample experience. …”
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Clinical and Laboratorial Features That May Differentiate 46,XY DSD due to Partial Androgen Insensitivity and 5α-Reductase Type 2 Deficiency by Nélio Neves Veiga-Junior, Pedro Augusto Rodrigues Medaets, Reginaldo José Petroli, Flávia Leme Calais, Maricilda Palandi de Mello, Carla Cristina Telles de Sousa Castro, Guilherme Guaragna-Filho, Letícia Espósito Sewaybricker, Antonia Paula Marques-de-Faria, Andréa Trevas Maciel-Guerra, Gil Guerra-Junior

“…The AR and SRD5A2 genes were sequenced in all cases. There were 9 cases (7 families) of 5α-RD2, 10 cases (5 families) of PAIS, and 39 patients had normal molecular analysis of SRD5A2 and AR genes. …”
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Altered Topological Properties of Grey Matter Structural Covariance Networks in Complete Thoracic Spinal Cord Injury Patients: A Graph Theoretical Network Analysis by Wen-Li Wang, Yu-Lin Li, Mou-Xiong Zheng, Xu-Yun Hua, Jia-Jia Wu, Fei-Fei Yang, Nan Yang, Xia He, Li-Juan Ao, Jian-Guang Xu

“…Only negative correlation was found between GMV of right middle OFC and SDS score in SCI patients (r=−0.503 and p=0.017), while no significant correlation between other abnormal brain regions and any of the clinical variables (all p>0.05). Conclusions. SCI patients would experience depressive and/or anxious feelings at the early stage. …”
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Weight loss for overweight and obese patients with prostate cancer: a study protocol of a randomised trial comparing clinic-based versus Telehealth delivered EXercise and nutrition... by Robert U Newton, Daniel A Galvão, Dennis R Taaffe, Suzanne K Chambers, David Joseph, Amanda Devine, Colin I Tang, Nigel Spry, Emily Jeffery, Dickon Hayne, Pedro Lopez, P Lyons-Wall, Christine Kudiarasu

“…However, the intervention needs to be accessible to all patients and not just those who can access a supervised clinic-based programme. …”
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TARGET Protein: the effect of augmented administration of enteral protein to critically ill adults on clinical outcomes—statistical analysis plan for a cluster randomized, cross-se... by Sophie Zaloumis, Matthew J. Summers, Jeffrey J. Presneill, Rinaldo Bellomo, Lee-anne S. Chapple, Marianne J. Chapman, Adam M. Deane, Suzie Ferrie, Craig French, Sally Hurford, Nima Kakho, Matthew J. Maiden, Stephanie N. O’Connor, Sandra L. Peake, Emma J. Ridley, An Tran-Duy, Patricia J. Williams, Paul J. Young, Amalia Karahalios, on behalf of the TARGET Protein Investigators, the Australian, New Zealand Intensive Care Society Clinical Trials Group

“…The statistical methods and models which will be used to estimate the effects for the primary and secondary outcomes are described. All statistical models will account for the cluster-randomized cross-over design to ensure correct estimation of the 95% confidence intervals. …”
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Use of thymidine kinase 1 autoantibody, thymidine kinase antigen, extracellular protein kinase A autoantibody, and C‐reactive protein for early detection of malignant tumors in dog... by Yoonhee Kim, Wonhee Lee, Byunggak Kim, Bonghwan Jang, Kyung‐Rok Yu, Hong Sook Kim, Minok Ryu, Yein Oh, Kyoungwon Seo, Chul Park, Ulsoo Choi, Dongha Bhang, Hwayoung Youn

“…The same multiple logistic regression analysis on dogs with lymphoma, and AUC of TK1 autoantibody model was 0.981 (all P < .0001, TK1 antigen P = .09), when the cutoff value was 0.352, the specificity was 92.9%, and sensitivity was 93.7%. …”
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Automated Video Assistant Referee in Lead Climbing by Eliane Künzler, David Roder, Urs Stöcker, Peter Wolf

“…RTMO achieved a 100% pose detection rate across all videos whereby a subsequent inspection showed that many false poses were considered as “detected”. …”
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Diagnostic value of macular blood flow in normal tension glaucoma by A.Sh. Zagidullina, V.U. Galimova, A.I. Arslanova, A.R. Nugmanova

“…</p> <p> <b>Patients and Methods: </b>patients aged 45–65 years with early newly diagnosed NTG (35 patients, 35 eyes) or POAG with elevated IOP (43 patients, 43 eyes) and healthy individuals without ocular disorders (n=50) were examined. All patients underwent OCTA by measuring vascular density (VD, %) using the ETDRS grid (central Fovea and Parafovea) and retinal thick-ness using the Angio Retina 3.0 protocol of the Optovue XR Avanti with the AngioVue function (Optovue, USA). …”
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Computational analysis of Newtonian fluid in a 2-D square cavity with kinetic energy, enstrophy, and palinstrophy in the presence of bottom corner obstacle by Dalmalka Praveen Kumar, Yadagiri Rameshwar, Rifaqat Ali, S. Nazari, Mohamed Kallel, Ahmed M. Galal

“…The physics involved in KE and vortex dynamics is that increasing obstacle height progressively reduces the kinetic energy across all configurations, with the sharpest decline (38 %) observed in dual-corner obstacles due to amplified flow constriction and enhanced boundary layer effects. …”
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Ambulance attendances involving personality disorder – investigation of crisis-driven re-attendances for mental health, alcohol and other drug, and suicide-related events by JH Broadbear, RP Ogeil, M McGrath, DS Scott, Z Nehme, F Moayeri, D Lubman, S Rao

“…Re-attendance was common; 8.3% of people accounted for 49.6% of all attendances involving personality disorder. …”
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Long-Term Outcomes of Caustic Esophageal Stricture with Endoscopic Balloon Dilatation in Chinese Children by Lan-Lan Geng, Cui-Ping Liang, Pei-Yu Chen, Qiang Wu, Min Yang, Hui-Wen Li, Zhao-Hui Xu, Lu Ren, Hong-Li Wang, Shunxian Cheng, Wan-Fu Xu, Yang Chen, Chao Zhang, Li-Ying Liu, Ding-You Li, Si-Tang Gong

“…We retrospectively reviewed the data of all patients who had a diagnosis of CES and underwent EBD from August 1, 2005, to December 31, 2014. …”
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Interleukin-10 exhibit dose-dependent effects on macrophage phenotypes and cardiac remodeling after myocardial infarction by Jing J. Zhang, Rodrigue Rizk, Xiaoping Li, Brandon G. Lee, Mason L. Matthies, Kennedy A. Bietz, Kang Kim, Kang Kim, Kang Kim, Johnny Huard, Yadong Wang, William C. W. Chen

“…Moreover, different doses of IL-10 differentially modulated myocardial gene expression, phagocytic cell infiltration at the infarct, LV fibrosis, and revascularization post-MI, with some, but not all, doses exerting beneficial effects.DiscussionOur study suggested that IL-10 has an effective dose range on Mφ phenotypes, and intramyocardial IL-10 treatment may trigger cardioprotective or unwanted effects post-MI in a dose-dependent manner.…”
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Artificial intelligence can help individualize Wilms tumor treatment by predicting tumor response to preoperative chemotherapy by Ahmed Nashat, Ahmed Alksas, Rasha T. Aboulelkheir, Ahmed Elmahdy, Sherry M. Khater, Hossam M. Balaha, Israa Sharaby, Mohamed Shehata, Mohammed Ghazal, Salama Abd El-Wadoud, Ayman El-Baz, Ahmed Mosbah, Ahmed Abdelhalim

“…K-fold cross-validation allowed the presentation of all data in the training and testing phases. Results: A total of 63 tumors in 54 patients were used to train and test the prediction model. …”
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Influence of substrate bias on the properties of CrAlN wear-resistant coating prepared by arc/magnetron composite technology by Xiaoyan NIU, Mingze LIU, Guoqiang DONG, Yujiang WANG, Haoliang TIAN

“…At a bias of −60 V, the coating exhibited minimal surface particles and pores, resulting in the best overall surface quality and excellent adhesion to the substate. Moreover, all coatings displayed the composite properties of metal and metal nitride mixtures. …”
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Age-related features of some plasminogen activation system components content and activity in the blood of benign and malignant uterine body tumors by I. V. Kaplieva, G. V. Zhukova, V. R. Zakharchenko, E. M. Frantsiyants, E. V. Verenikina, Yu. A. Pogorelova, P. S. Kachesova, Yu. Yu. Kozel, N. A. Maximova, M. G. Ilchenko, E. I. Agarkova, A. S. Egorova

“…The indicators of LM patients were characterized by the minimum value of the ratio “t-PA activity/u-PA activity in the blood” among all studied subgroups of patients. Age-related features of the researched parameters were observed more often in the cases of LM than in the cases of UCEC. …”
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Evaluation of wheat products with high flavonoid content: justification of importance of marker-assisted development and production of flavonoid-rich wheat cultivars by E. K. Khlestkina, N. I. Usenko, E. I. Gordeeva, O. I. Stabrovskaya, I. B. Sharfunova, Y. S. Otmakhova

“…In parallel with the evaluation of the anthocyanins content in all samples, the mass fraction of antioxidants was measured by using the amperometric method. …”
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Beyond variance: simple random distributions are not a good proxy for intraspecific variability in systems with environmental structure by Girard-Tercieux, Camille, Vieilledent, Ghislain, Clark, Adam, Clark, James S., Courbaud, Benoit, Fortunel, Claire, Kunstler, Georges, Pélissier, Raphaël, Rüger, Nadja, Maréchaux, Isabelle

“…Communities simulated with unstructured IV never reached the community diversity and composition of those where all the variation was explained and structured (perfect knowledge model). …”
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Treatment patterns for chronic obstructive pulmonary disease under the tiered medical system by Xiaoli Wang, Xingru Zhao, Tianqi Cen, Yi Yu, Zhiwei Xu, Lijun Shen, Ziqi Wang, Paul Jones, Quncheng Zhang, Yunxia An, Xiaoju Zhang

“…Dual bronchodilators (long-acting β2-agonists /long-acting muscarinic antagonist, LABA/LAMA) represented the least common medication regimen across all tiers of hospitals, albeit their usage rates increased in tandem with hospital tier (0.7% vs. 7.2% vs. 10.4%, P < 0.001). …”
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