Comparison of the STANDARD M10 C. difficile, Xpert C. difficile, and BD MAX Cdiff assays as confirmatory tests in a two-step algorithm for diagnosing Clostridioides difficile infec... by Hyunseul Choi, Minhee Kang, Sun Ae Yun, Hui-Jin Yu, Eunsang Suh, Tae Yeul Kim, Hee Jae Huh, Nam Yong Lee

“…This study evaluated the performance of three commercial NAATs (M10, Xpert, and BD MAX assays) using 200 archived stool specimens initially tested as glutamate dehydrogenase (GDH)-positive but toxin-negative by GDH/toxin A/B enzyme immunoassay, the first step in the two-step algorithm. All three assays demonstrated high sensitivity (89.1% to 95.8%) and specificity (86.4% to 92.6%), with low rates of invalid results (≤1%). …”
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SNP2-Lys-C markers inheritance, genes expression, and the resistance of second-generation Catfish Clarias gariepinus against Aeromonas hydrophila infection by Yudha Hanggara, Alimuddin Alimuddin, Dinar Tri Soelistyowati Tri Soelistyowati, Sri Nuryati

“…The findings indicate that all G2 seed possess the TT genotype and exhibit a higher survival rate compared to the dominant CT genotype seed. …”
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Differential diagnostic value of P wave dispersion and QT interval dispersion between psychogenic pseudosyncope and vasovagal syncope in children and adolescents by Zifeng Huang, Yi Xu, Shuo Wang, Ping Liu, Xingfang Zen, Yuwen Wang, Fang Li, Runmei Zou, Cheng Wang

“…Conclusions In children and adolescents, electrocardiogram parameters such as Pmax, Pd, QTmax, QTd, and QTcd all possess predictive value in differentiating between PPS and VVS. …”
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Morphokinetic Analyses of Fishing Cat–Domestic Cat Interspecies Somatic Cell Nuclear Transfer Embryos Through A Time-Lapse System by Hai-Jun Liu, Serena Jocelyn Wai Yin Oh, Nicole Liling Tay, Christina Yingyan Lim, Chia-Da Hsu, Delia Hwee Hoon Chua, Winnie Koon Lay Teo, Yuin-Han Loh, Soon Chye Ng

“…The results show that morula and blastocyst development rates were significantly lower in the iSCNT embryos compared to their IVF counterparts. All earlier time points of embryonic development before the onset of blastulation in the iSCNT embryos were significantly delayed when compared with their IVF counterparts. …”
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Outcomes of percutaneous endoscopic gastrostomy (PEG) in HIV patients by Nikhitha Mantri, Haozhe Sun, Sameer Datta Kandhi, Nishant Allena, Muhammad Yasir Anwar, Vibha Hayagreev, Shalini Penikilapate, Ahmed Alemam, Hassan A Muntazir, Trishna Acherjee, Harish Patel, Jasbir Makker

“…Methods Our study comprised a total of 639 PEG tubes placed on 461 unique patients, from which 85 patients (n = 18%) were HIV positive. We reviewed all these PEG tube patients at our institution and compared their complications and mortality outcome between the two groups of HIV positive as against HIV negative. …”
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Longitudinal exploration of cancer-related cognitive impairment in patients with newly diagnosed aggressive lymphoma: protocol for a feasibility study by Vincent Dore, Christopher C Rowe, Meinir Krishnasamy, Haryana Dhillon, Adam K Walker, Karla Gough, Priscilla Gates, Carlene Wilson, Eliza Hawkes, Yuliya Perchyonok, Janette L Vardy, Michiel de Ruiter

“…Patients will complete comprehensive assessments at three time points: baseline (time 1, pre-treatment) and two post-baseline follow-up assessments (time 2, mid-treatment and time 3, 6–8 weeks post-treatment completion). All patients will be assessed for self-reported cognitive difficulties and objective cognitive function using Stroop Colour and Word, Trail Making Test Part A and B, Hopkins Verbal Learning Test-Revised, Controlled Oral Word Association and Digit Span. …”
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Hubungan Antara Cache, Energy Consumption dan Runtime Performance pada Progressive Web Apps by Wakhid Kurniawan, Agung Fatwanto

“…Service Workers at the core have the ability to intercept and handle network requests, including managing programmatic response caches. All Service worker capabilities are cached. These advantages of course have implications for performance. …”
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The normal cell proliferation and wound healing effect of polysaccharides from Ganoderma amboinense by Shuangzhi Zhao, Ming Lei, Hui Xu, Hailun He, Alexander Suvorov, Junhua Wang, Jiying Qiu, Qingxin Zhou, Jinyu Yang, Leilei Chen

“…The wound healing effect of GAMPS (0.1 μg/μL) was obvious on NIH/3T3 and 3.75 μg/μL of GAMPS showed the strongest total antioxidant ability. All the results indicate that GAMPS promotes cell proliferation, and has cell wound healing effect and strong antioxidant activity. …”
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Targeted reproductive management for lactating Holstein cows: Economic return by Ricardo C. Chebel, Tomas Gonzalez, Ana B. Montevecchio, Klibs N. Galvão, Albert de Vries, Rafael S. Bisinotto

“…Control cows were re-inseminated based on visual or patch-aided detection of estrus, whereas TRM cows were re-inseminated as described for control cows with the aid of the AMD. All cows received a GnRH injection 27 ± 3 d after AI and, if diagnosed as nonpregnant, completed the 5-d CoSynch protocol and received TAI 35 ± 3 d after insemination. …”
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Development and use of a fully automatic clinical intelligent milk dispenser (一种全自动临床智能配奶机的研制与使用) by ZHANG Rongbang (张榕邦), OUYANG Li (欧阳丽), JIN Mu (金募), LIU Lingzhi (刘羚芷), LIN Yan (林妍), ZHANG Zhiyuan (张秩源)

“…The controls of these control panels are all connected to the main control circuit board. …”
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A Novel Unilateral Bi/Multi‐Portal Endoscopic Transforaminal Interbody Fusion Utilizing Uniaxial Spinal Endoscope Instead of Arthroscope: Technical Note and Preliminary Clinical Re... by Liyu Yang, Long Zhou, Min Qiu, Feng Liang, Liqing Yang, Qin Fu, Gen Ba

“…Furthermore, a follow‐up CT scan conducted 12 months post‐surgery showed 100% fusion rate of the surgical segments in all patients. Conclusion UME‐TLIF is an endoscopy‐assisted fusion procedure that minimizes muscle damage in patients and allows early rehabilitation. …”
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Cost-savings and health impact of strategies for prevention of Respiratory Syncytial Virus with nirsevimab in Chile based on the integrated analysis of 2019–2023 national databases... by Denis Sauré, Miguel O’Ryan, Juan Pablo Torres, Natalia Trigo, Gonzalo Diaz, Marcel Goic, Charles Thraves, Jorge Pacheco, Patricio Aguilera, Andrea Caro, Leonardo J. Basso

“…Findings: With nirsevimab costing about USD$225 per dose, immunizing infants under 6 months before the RSV season, all newborns during the season, and high-risk groups would have been cost-saving in 2023 and 2019. …”
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Outcome of critically ill patients receiving systemic chemotherapy on the intensive care unit by Panagiotis Karagiannis, Felix Klingler, Viktor Arelin, Winfried Alsdorf, Christina König, Kevin Roedl, Walter Fiedler, Katja Weisel, Stefan Kluge, Carsten Bokemeyer, Dominic Wichmann

“…ObjectiveAnalyze the outcomes of critically ill patients who developed new-onset organ dysfunction and received systemic chemotherapy during their ICU stay.DesignRetrospective cohort study.SettingA tertiary medical center in Germany with an Intensive Care Medicine department consists of 11 intensive care units comprising 140 beds, serving all subspecialties of adult intensive care medicine.Patients167 patients receiving systemic oncological treatment from January 1st, 2015 to December 31st, 2021, with a data cut-off on December 31st, 2022.InterventionsNone.Measurements and main resultsA total of 167 patients were included. …”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

“…Ly6c+ macrophages in murine BA showed increased expression for Hif1a and other genes involved in the cellular response to hypoxia. Among all subsets, the number of Ly6c+ macrophages exhibited the strongest correlation with severity of histologic liver injury by Ishak score.ConclusionsOur data identify specific pathways upregulated in Ly6c vs MHCII+ macrophage subsets in murine BA. …”
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Diagnostic Efficacy of ¹²³Iodo-Metaiodobenzylguanidine SPECT/CT in Cardiac vs. Neurological Diseases: A Comparative Study of Arrhythmogenic Right Ventricular Cardiomyopa... by Johannes M. Hagen, Maximilian Scheifele, Mathias J. Zacherl, Sabrina Katzdobler, Alexander Bernhardt, Matthias Brendel, Johannes Levin, Günter U. Höglinger, Sebastian Clauß, Stefan Kääb, Andrei Todica, Guido Boening, Maximilian Fischer

“…SUV_median, and SUV_peak demonstrated a significant difference between ARVC and α-synucleinopathies across all regions, with the α-synucleinopathy group showing a lower uptake. …”
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Designing a multi-epitope vaccine candidate against human rhinovirus C utilizing immunoinformatics approach by Tajul Islam Mamun, Tajul Islam Mamun, Md. Ahad Ali, Md. Nazmul Hosen, Jillur Rahman, Md. Anwarul Islam, Md. Golam Akib, Kamruz Zaman, Md. Masudur Rahman, Md. Masudur Rahman, Ferdaus Mohd Altaf Hossain, Ferdaus Mohd Altaf Hossain, Samir Ibenmoussa, Mohammed Bourhia, Turki M. Dawoud

“…Human rhinovirus C (HRV-C) is a significant contributor to respiratory tract infections in children and is implicated in asthma exacerbations across all age groups. Despite its impact, there is currently no licensed vaccine available for HRV-C. …”
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Association Between Adolescent Violence Exposure and the Risk of Suicide: A 15-Year Study in Taiwan by Chieh Sung, Chi-Hsiang Chung, Chien-An Sun, Chang-Huei Tsao, Daphne Yih Ng, Tsu-Hsuan Weng, Li-Yun Fann, Fu-Huang Lin, Wu-Chien Chien

“…Among adolescents who had experienced violence, the methods of suicide included poisoning (solid and liquid) (53.6% vs. 43.2%), hanging (1.2% vs. 0.6%), firearms (2.4% vs. 0%), and cutting instruments (27.4% vs. 22.8%), all of which were significantly higher than in the control group. …”
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Research Status and Direction of Chronic Obstructive Pulmonary Disease Complicated with Coronary Heart Disease: A Bibliometric Analysis from 2005 to 2024 by Bian H, Zhu S, Xing W, Qi L, Xue J, Peng X, Jin Z, Zhao H

“…Through keyword clustering analysis, we categorized all keywords into three distinct groups: management strategies for COPD and CHD; diseases associated with both conditions; and epidemiological characteristics concerning their burden—current hotspots include multimorbidity factors such as hypertension and obesity alongside outcomes like diagnosis during COVID-19 pandemic implications within societal contexts are highlighted here too.Conclusion: Presently focused research on COPD coupled with CHD primarily revolves around five key areas: pathogenesis exploration, early diagnostic techniques, COVID-19 infection, dynamics intervention, methodologies, and treatment protocol development efforts. …”
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Investigating neuropathological correlates of hyperactive and psychotic symptoms in dementia: a systematic review by Giulia Negro, Giulia Negro, Michele Rossi, Camillo Imbimbo, Alberto Gatti, Andrea Magi, Andrea Magi, Ildebrando Marco Appollonio, Ildebrando Marco Appollonio, Alfredo Costa, Alfredo Costa, Tino Emanuele Poloni, Tino Emanuele Poloni

“…HIDA-P symptoms were distributed across all clinical diagnoses, with agitation (14.00%), delusions (11.60%), disinhibition (7.61%), and hallucinations (6.83%) being the most frequently reported behaviors. …”
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New Insights on Continuous Renal Replacement Therapy for Acute Respiratory Distress Syndrome: A Systematic Review and Meta‐Analysis by Siyao Zeng, Shanpeng Cui, Yue Li, Zhipeng Yao, Yunlong Li, Yang Cao, Lianghe Wen, Ming Li, Junbo Zheng, Hongliang Wang

“…This meta‐analysis compiles all existing RCTs to assess whether CRRT benefits ARDS. …”
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