Deep learning-based synthetic CT for dosimetric monitoring of combined conventional radiotherapy and lattice boost in large lung tumors by Hongwei Zeng, Xiangyu E, Minghe Lv, Su Zeng, Yue Feng, Wenhao Shen, Wenhui Guan, Yang Zhang, Ruping Zhao, Jingping Yu

“…Dosimetric parameters of all OARs were significantly higher than those in the original treatment plan (P < 0.01). …”
Get full text

Development of a phenomena identification and ranking table (PIRT) for intermediate break loss-of-coolant accident in PWRs by Hae Min Park, Jong Hyuk Lee, Chiwoong Choi, Kwi-Seok Ha, Byung Hyun You, Jaeseok Heo, Kyung Doo Kim, Sung Won Bae, Seung Wook Lee, Dong Hyuk Lee, Sang Ik Lee, Chan Eok Park, Bub Dong Chung, Kwang Won Seul

“…Based on IBLOCA analyses using the safety and performance analyzing code (SPACE), the PIRT panel defined the temporal phases, systems, components and possible phenomena during an IBLOCA. For all possible phenomena, the relative importance and the knowledge level were determined for each component and each phase via discussions among PIRT panel members. …”
Get full text

Discussion Paper for the Foundation for the Rights of Future Generations - The housing crisis as a problem of intergenerational justice: The case of Germany by Elena Lutz

“…Yet, because of architectural and socio-economic differences between and within cities, there exists no one-sizefits-all solution. Nevertheless, the above measures can serve as a starting point for developing comprehensive measures to fight intergenerational injustice in the German housing market. …”
Get full text

Comparative efficacy and acceptability of psychotherapies for post-traumatic stress disorder in children and adolescents: a systematic review and network meta-analysis by Andrea Cipriani, Pim Cuijpers, Yuqing Zhang, David Cohen, Jürgen Barth, Peng Xie, Cinzia Del Giovane, Xinyu Zhou, Donna Gillies, Teng Teng, Xuemei Li, Li Fan, Yajie Xiang, John R. Weisz, Xueer Liu, Yuanliang Jiang, Kang Du, Arun V. Ravindran

“…For efficacy, cognitive processing therapy (CPT), behavioural therapy (BT), individual trauma-focused cognitive–behavioural therapy (TF-CBT), eye movement desensitisation and reprocessing, and group TF-CBT were significantly superior to all control conditions at post-treatment and follow-up (SMDs between −2.42 and −0.25). …”
Get full text

A SARS‐CoV‐2 EG.5 mRNA vaccine induces a broad‐spectrum immune response in mice by Hongyu Wang, Qinhua Peng, Xinxian Dai, Zhifang Ying, Xiaohong Wu, Xinyu Liu, Hongshan Xu, Jia Li, Leitai Shi, Jingjing Liu, Yunpeng Wang, Danhua Zhao, Yanqiu Huang, Lihong Yang, Ren Yang, Guangzhi Yue, Yue Suo, Qiang Ye, Shouchun Cao, Yuhua Li

“…Th1‐biased cellular immune response was induced in all vaccination groups. The antigen design and immunization strategy of this study have reference significance for the research of the next generation of COVID‐19 vaccine and other vaccines.…”
Get full text

Preparation of Tragopogon graminifolius-loaded electrospun nanofibers and evaluating its wound healing activity in a rat model of skin scar by Leila Almasi, Elham Arkan, Mohammad Hosein Farzaei, Amin Iranpanah, Cyrus Jalili, Fatemeh Abbaszadeh, Faranak Aghaz, Sajad Fakhri, Javier Echeverría

“…To evaluate the wound healing effects, rats were divided into four distinct groups, including negative control (untreated), phenytoin cream (as positive control), polymer (PVA/PEO/CS), and drug (nanofiber-containing 50% of TG extract; named PVA/PEO/CS/TG) groups. All treatments were administered topically once daily for 14 days. …”
Get full text

Refraction in adolescents with various severity of Internet addiction and intensity of device use by T.R. Mukhamadeev, R.R. Akhmadeev, E.F. Shaykhutdinova, A.R. Khusniyarova

“…Khusniyarova¹ </p> <p> ¹Bashkir State Medical University, Ufa, Russian Federation </p> <p> ²All-Russian Center for Eye and Plastic Surgery of the Bashkir State Medical University, Ufa, Russian Federation </p> <p> ³CJSC "Optimedservis", Ufa, Russian Federation </p> <p> <b>Aim:</b> to assess refraction in adolescent Internet users with various severity of Internet addiction and intensity of device use. …”
Get full text

The lamprey habenula provides an extreme example for the temporal regulation of asymmetric development by Lucile Guichard, Ronan Lagadec, Léo Michel, Hélène Mayeur, Michaël Fuentès, Jordan Pain, Noah Heier, Quentin Rougemont, Maria Celina Rodicio, Antón Barreiro-Iglesias, Antón Barreiro-Iglesias, Patrick Blader, Michael Schubert, Sylvie Mazan

“…The dorsal right subdomain forms and already expresses all identified signature markers in prolarval stages. …”
Get full text

Pilot study of a comprehensive multidisciplinary inpatient-based approach to smoking cessation in patients with vascular disease by Tanner Kim, MD, Anand Brahmandam, MBBS, Dana Alameddine, MD, Rachel Forman, MD, Amin Hardik, MD, Lisa Fucito, PhD, Carlos Mena-Hurtado, MD, Raul Guzman, MD, Cassius Iyad Ochoa Chaar, MD, MS, MPH

“…The mean number of cigarettes consumed before enrollment was 17 ± 9 per day over a mean period of 40 ± 11 years. All patients had previously attempted to quit smoking and 97% had received advice from their surgeons or interventionalists to quit smoking in the prior year. …”
Get full text

Eco-friendly alginate/PCL-TiO2 hybrid biocomposites: Preparation, properties, and methylene blue photodegradation by Bunga Fisikanta Bukit, Agus Wedi Pratama, Erna Frida, Bakti Berlyanto Sedayu, Dina Fransiska, Deni Purnomo, Emma Rochima, Istiqomah Rahmawati, Sona Suhartana, Firda Aulya Syamani

“…TGA results showed that all samples exhibited two stages of decomposition. …”
Get full text

Pengaruh Diet Tinggi Minyak Sawit Terhadap Sel Hepatosit Tikus by Susila Sastri, Husnil Kadri

“…Fifteen male wistar rats with 200-250 gram weight which divided into three group of five rats each, i.e. negative control (standard diet 6-7gr/day), positive control (standard diet ad libitum), and high palm oil group (standard diet with 50% palm oil ad libitum). After 4 weeks, all rats were slaughtered to take the livers, then the liver were preserved in formaldehyde for stained with haematoxylin eosin (HE) on the glass object. …”
Get full text

The effects of different cooking methods on some fatty acid composition in sea bass grown in marine, freshwater, and culture environments by Ali Şen, Gürkan Uçar

“…<p> <b>Conclusion: </b>According to all fish groups and cooking methods, grilled wild sea bass is the most suitable in terms of omega-3. …”
Get full text

Interference of a phytoconstituent from Nymphaea lotus-derived ligand N-acetyl glucosamine with signaling receptors in diabetes mellitus development: A targeted computational analy... by Sunday Amos Onikanni, Tran Nhat-Phong Dao, Adewale Oluwaseun Fadaka, Halliru Zailani, Oluwafemi Shittu Bakare, Omolola Esther Amos, Ashwil Klein, Valens Munyembaraga, Morenike Grace Ajayi, Adebola Iyabode Akinjokun, Babatunji Emmanuel Oyinloye, Leandro Miranda-Alves

“…Diabetes mellitus is a world-wide health concern with several millions affected in all ages. Computer-aided drug design (CADD) is a powerful tool that has revolutionized the process of discovering and developing new drugs. …”
Get full text

Safety and efficacy of CD33-targeted CAR-NK cell therapy for relapsed/refractory AML: preclinical evaluation and phase I trial by Ruihao Huang, Xiaoqi Wang, Hongju Yan, Xu Tan, Yingying Ma, Maihong Wang, Xiao Han, Jia Liu, Li Gao, Lei Gao, Guangjun Jing, Cheng Zhang, Qin Wen, Xi Zhang

“…Although chimeric antigen receptor (CAR)-T-cell therapy has shown promising effects in acute lymphoblastic leukemia (ALL) and lymphoma, its application in R/R AML is limited by “off-target” effects, which lead to severe bone marrow suppression and limit its clinical application. …”
Get full text

Molecular mechanisms impact on fluoroquinolone resistance among E.coli from enteric carriage monitoring before prostate biopsy and earliest description of qnrB81 by Rehaiem Amel, Bouzouita Abderrazek, Ferjani Sana, Saadi Ahmed, Zrelli Mariem, Kanzari Lamia, Ferjani Asma, Mohamed Riadh Ben Slama, Boutiba Ben Boubaker Ilhem

“…From February 2016 to December 2018, the incidence of rectal carriage of Qs-FQs resistant Enterobacterales detected from rectal swabs of patients before undergoing (TRUS-BP) was 61.06% (80/131) all related to E. coli species. Based on the MICs range of Qs (24–256 mg/L) and FQs (0.24–128 mg/L) breakpoint by EUCAST, we categorized these E. coli isolates into three resistance profiles (I, II, and III) associated with the patterns of chromosomal mutations in the quinolone resistance-determining regions (QRDRs) of gyrA and parC and the plasmid-mediated quinolone resistance encoding genes (PMQRs) detected by PCR-based assay and sequencing; MICs increase in an escalation step according to the co-occurrence of multiple molecular mechanisms. …”
Get full text

Development of a new data management system for the study of the gut microbiome of children who are small for their gestational age by Felix Manske, Magdalena Durda-Masny, Norbert Grundmann, Jan Mazela, Monika Englert-Golon, Marta Szymankiewicz-Bręborowicz, Joanna Ciomborowska-Basheer, Izabela Makałowska, Anita Szwed, Wojciech Makałowski

“…The main goals of the system are to store the pre-computed study data securely under concurrent load and to make downstream analyses accessible to all researchers, regardless of programming proficiency. …”
Get full text

Salvage radiofrequency ablation followed by external beam radiotherapy for inoperable recurrent differentiated thyroid cancer by Chung-Shih Chen, Sheng-Dean Luo, Yen-Hsiang Chang, Chen Kai Chou, Shun-Yu Chi, Shao-Chun Wu, Yen-Hao Chen, Johnson Chia-Shen Yang, Eng-Yen Huang, Yu-Ming Wang, Wei-Che Lin

“…With a median follow-up period of 33.7 months, all patients maintained locoregional control, while achieving a 2-year survival rate of 90.9%. …”
Get full text

Network Design and Route Analysis Using Outside Plant by Isaac Adjaye Aboagye, Nii Longdon Sowah, Wiafe Owusu-Banahene, Aryee Shaelijah, Margaret Ansah Richardson, Emmanuel Baah-Boadi

“…FAT Power (dBm) for feeder lines 1, 2, 3, and 4 and distribution lines 1, 2, 3, and 4, respectively, were all within the acceptable range. The design will help to reduce the cost of repairing damaged cables drastically. …”
Get full text

End of Pandemic Parental Hesitancy Towards Pediatric COVID-19 Vaccination: A Cross-sectional Survey at Two Lebanese Tertiary Hospitals by Sabine Shehab, Lina Anouti, Celina F. Boutros, Christelle Radi, Silma El Baasiri, Arabia Badih, Rawan Korman, Marwa El Masri, Joudie Alwan, Maha Monzer, Yara Bitar, Mona Kassem, Mayse Naser, Yara Salameh, Sarah Khafaja, Murielle Bou Ghosn, Dany Al Hamod, Sarah Ghadban, Soha Ghanem, Ghassan S. Dbaibo

“…Only 9.4% had vaccinated all eligible children. The main parental concern was the vaccine’s safety and perceived lack of testing (p < 0.001). …”
Get full text

Prognostic value of multi-PLD ASL radiomics in acute ischemic stroke by Zhenyu Wang, Yuan Shen, Xianxian Zhang, Qingqing Li, Congsong Dong, Shu Wang, Haihua Sun, Mingzhu Chen, Xiaolu Xu, Pinglei Pan, Pinglei Pan, Zhenyu Dai, Fei Chen, Fei Chen

“…Statistical analysis using the DeLong test revealed its significant outperformance compared to both the clinical model (AUC = 0.658, p &lt; 0.001) and the CBF radiomics model (AUC = 0.755, p = 0.002). The robustness of all models was confirmed through permutation testing. …”
Get full text