Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy by S. Rossi, R. Maisto, C. Gesualdo, M. C. Trotta, F. Ferraraccio, M. K. Kaneva, S. J. Getting, E. Surace, F. Testa, F. Simonelli, P. Grieco, F. Merlino, M. Perretti, M. D’Amico, C. Di Filippo

“…Finally, application of MC3-MC4 agonist/antagonists resulted to be inactive with respect to all parameters under assessment.…”
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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

“…The collected data will be linked to secondary sources such as cancer registries and National Health Insurance Service data to provide a comprehensive analysis of the impact of hereditary cancer on health and survival.Ethics and dissemination The study protocol was approved by all the Ethics Committees: the National Cancer Center IRB (NCC2023-0179), the Samsung Medical Center IRB (SMC2023-09-057), the Yonsei University Health System, Severance Hospital IRB (4-2023-0627), the Hanyang University Guri Hospital IRB (GURI2023-08-021) and the Keimyung University IRB (DSMC IRB 2024-05-048). …”
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Hand grip strength in dentists: A comprehensive evaluation of head position, dominance, age, and sex by Hayam Mahmoud, K. M. Shalabi, Kadrya H. Battecha, Ehab Mohamed Abd El-Kafy, Mohamed Salaheldein Alayat, Anwar A. Ebid, Jana Sami Ahmad, Atheer Mohammed Alotaibi, Nouf Fayez Alsfyani, Jumana Jamaan Alzhrani

“…In a comparison between male and female DP and DS, males had stronger grip than females across all positions. Hand dominance significantly influences HGS, with the dominant having a stronger hand grip. …”
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Clinical and Onychoscopy Patterns in Fingernail Onychomycosis—A Study by the International Dermoscopy Society Trichoscopy And Onychoscopy Task Force by Matilde Iorizzo, Bianca Maria Piraccini, Aurora Alessandrini, Francesca Bruni, Laura Vollono, Francesca Pampaloni, Nilton Gioia Di Chiacchio, Nilton Di Chiacchio, Juan Jimenez-Cahue, Chander Grover, Zoe Apalla, Asmahne Souissi, Awatef Kelati, Eirini Kyrmanidou, Elizabeth Lazaridou, Michela Starace

“…Major clinical and onychoscopic features observed included onycholysis, subungual hyperkeratosis, leukonychia, chromonychia and absence of the cuticles. On the basis of all findings, 4 main types of fingernail onychomycosis were identified. …”
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A qualitative systematic review of umbilical cord care practices in Nigeria by Precious Ebube Anyakorah, Florence Chinelo Aguna, David Chinaecherem Innocent, Anthony Chinonso Uwandu-Uzoma, Uzochukwu Godswill Ekeleme, Chidera Chisom Obasi, Stanley Chinedu Eneh, Chidinma Peace Ahunam, Ihuoma Chimdimma Dike, Vivian Chidimma Maduekwe, Oluwaseunayo Deborah Ayando, Chinazaekpere Oguguo Duruji, Rejoicing Chijindum Innocent, Princess Chidiebube Uwaezuoke, Oluwafunmilayo Opeyemi Adenuga, Chiagoziem Ogazirilem Emerole

“…Cultural beliefs, a lack of healthcare infrastructure, and socioeconomic circumstances all have a big impact on cord care decisions. Disparities in knowledge and adherence to evidence-based procedures are noticeable, particularly in the use of chlorhexidine gel. …”
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Resistive switching mechanisms in BiFeO3 devices with YBCO and Ag as top electrodes by Santiago Ceballos Medina, Lorena Marín Mercado, Alexander Cardona-Rodríguez, Mario Fernando Quiñonez Penagos, César Magén, Luis Alfredo Rodríguez, Juan Gabriel Ramírez

“…The devices were fabricated using reactive sputtering at high oxygen pressure, and their RS mechanisms were investigated via current-voltage (I-V) measurements. We find all devices exhibit unipolar behavior, with symmetric RS behavior observed in devices with YBCO top electrodes and asymmetric RS in those with Ag top electrodes. …”
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Helical Magnetic Field in a Massive Protostellar Jet by A. Rodríguez-Kamenetzky, A. Pasetto, C. Carrasco-González, L. F. Rodríguez, J. L. Gómez, G. Anglada, J. M. Torrelles, N. R. C. Gomes, S. Vig, J. Martí

“…Despite the diversity of their driving sources, it is believed that all jets are different manifestations of a single universal phenomenon. …”
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Differential coping capacities underlie the overall resistance of temperate seagrasses to herbivory by J. Boada, T. M. Smith, A. M. Ricart, T. Alcoverro, M. Pérez, J. Romero, N. Sanmartí, Y. Ontoria, M. Pierrejen, R. Arthur, D. Alonso, M. P. Adams, F. Rossi

“…After months of exposure to cumulative herbivory, all three species showed signs of stability. Interestingly, none of the species disappeared completely even when exposed to extreme herbivory. …”
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Prognosis and factors related to severe secondary hyperparathyroidism in long-term peritoneal dialysis patients by Yanmei Li, Xiaonan Feng, Na Chen, Shuhua Song, Min Yu, Yan Wang, Hongxia Zhang, Li Wang, Menghua Chen, Na Tian

“…This retrospective cohort study investigated risk factors for sSHPT and the association between SHPT and mortality (all-cause and infection-related) among 771 clinically stable patients (421 male patients; mean age, 51.2 years; median dialysis vintage, 28.3 months) who underwent >3 months of regular peritoneal dialysis (PD) between January 2013 and March 2021. …”
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Concurrent severe fever with thrombocytopenia syndrome virus outbreaks on multiple fox farms, China, 2023 by Jian Sun, Lei Qian, Delong Li, Xiurong Wang, Hong Zhou, Cixiu Li, Edward C. Holmes, Jianke Wang, Juan Li, Weifeng Shi

“…Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) was identified in tissue/organ and swab samples from all the 13 foxes collected from these farms. These animals exhibited loss of appetite and weight loss, finally resulting in death. …”
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Whole-body tumor segmentation from FDG-PET/CT: Leveraging a segmentation prior from tissue-wise projections by Sambit Tarai, Elin Lundström, Nouman Ahmad, Robin Strand, Håkan Ahlström, Joel Kullberg

“…Finally, the segmentation prior was provided as an additional input channel along with the CT and SUV images to three variants of 3D segmentation networks (3D UNet, dynUNet, nnUNet) to enhance the overall tumor segmentation performance. All the methods were independently evaluated using 5-fold cross-validation on the autoPET dataset and subsequently tested on the U-CAN dataset.Results:Combining the segmentation prior with the original SUV and CT images improved overall tumor segmentation performance significantly compared to a baseline network. …”
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Effects of non-contact electric fields on the kidneys and livers of tumour-bearing rats [version 6; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Luthfi Nurhidayat, Ahmad Ghitha Fadhlurrahman, Firman Alamsyah, Warsito Purwo Taruno, Nisrina Firdausi, Subekti Evi Dwi Nugraheni, Rarastoeti Pratiwi

“…There was no significant cellular damage, congestion, and haemorrhage in the livers of all groups, except in the healthy rat group that showed significantly higher haemorrhage. …”
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Penerapan Metode K-Medoids untuk Pengelompokan Mahasiswa Berpotensi Drop Out by Syamsul Bahri, Dwi Marisa Midyanti

“…The cluster results from 389 data, obtained 3 attributes that have different value ranges between clusters, namely GPA, IP Semester 1, and Scholarship Status, all three attributes are distinguishing feature between clusters. …”
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Sociodemographic index–age differences in the global prevalence of cardiovascular diseases, 1990–2019: a population-based study by Xunliang Li, Channa Zhao, Mengqian Liu, Wenman Zhao, Haifeng Pan, Deguang Wang

“…SDI levels were negatively associated with faster increases in the age-standardized prevalence rate of CVD across all ages and age groups. Low SDI countries consistently showed the highest age-standardized prevalence rates of CVD in the younger age groups (0–14 and 15–49 years), while high-middle SDI countries had the highest rates in the older age groups (50–69 and ≥ 70 years). …”
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Photothermal performance of nanofluids: An experimental study on direct absorption solar energy conversion using graphene oxide and its binary composites for water purification by Abdul Sattar, Bai Bofeng, M. Adeel Munir, Muhammad Farooq, S. Bilal, M. Imran Khan, Noreen Sher Akbar, Mohammed Ilyas Khan, Mohammad Rehan, Fahid Riaz

“…An increase in photothermal efficiency and a decrease in specific absorption rate (SAR) were observed with increasing nanoparticle concentration. 92 % photothermal conversion efficiency in the case of pure (100 %) GO at 0.03 wt% was obtained which is the highest among all the nanofluids used in this work. The best photothermal performance of pure (100 %) GO was achieved due to maximum solar absorption, dark color, highest thermal conductivity and excellent dispersion stability. …”
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Network Meta-Analysis and Trial Sequential Analysis of Randomised Controlled Trials Comparing Robotic, Laparoscopic, and Open Pancreatoduodenectomy by Nejo Joseph, MBChB, Chris Varghese, MBChB, James Lucocq, MBChB, Matthew J. McGuinness, MBChB, Samuel Tingle, MBChB, Giovanni Marchegiani, PhD, Kjetil Soreide, PhD, Mohammed Abu-Hilal, Jas Samra, Marc Besselink, PhD, Steve White, Sanjay Pandanaboyana, FRCS

“…With recent randomised controlled trials (RCTs) comparing open pancreatoduodenectomy (OPD) with robotic or laparoscopic pancreatoduodenectomy (RPD or LPD), we undertook a network meta-analysis (NMA) comparing all 3 approaches to evaluate comparative outcomes. …”
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Strengthening identification and characterization of causes of perinatal deaths in Kaski district of Nepal (Perinatal MITS Nepal) by Nuwadatta Subedi, Sunita Ranabhat, Sanjib Mani Regmi, Mukesh Mallik, Dela Singh, Shree Krishna Shrestha, Bandana Gurung, Arjun Bhattarai, Madan Prasad Baral, Sudhir Raman Parajuli, Ramchandra Bastola, Junu Shrestha, Sahisnuta Basnet, Eva Gauchan, Sabita Paudel

“…We will also conduct verbal autopsy (VA) among community perinatal deaths reported in the district. All the perinatal deaths reported in the study sites will be enrolled in the first stage of the study. …”
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No rumen fermentation profiles and associated microbial diversities difference were found between Hu sheep and Karakul sheep fed a cottonseed hull diet by Jishu Wang, Guangxu E, Meng Zhang, Yanlong Zhang, Tiantian Bai, XuanXuan Pu, Junfeng Liu, Xuefeng Guo, Subir Sarker, Long Cheng

“…Results The 16S rRNA sequencing analysis revealed no significant differences in the relative abundance or dominant bacterial communities in the rumen across all stages. In stage II, rumen bacteria in both Hu and Karakul sheep were relatively stable. …”
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The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies by Büşra Karpuz Ağören, Mahmut Sinan Erez, Esma Kozan, Aydın Dağyaran, Mevlüt Akdağ, Eduardo Sobarzo-Sánchez, Esra Küpeli Akkol

“…The anthelmintic activity of the plant extracts on gastrointestinal nematode eggs and larvae (L3) of the sheep was assessed using in vitro test methods such as the egg hatch assay and larval motility assay, conducted over a 24 h period (1, 2, 3, 4, 6, 8, 24). All extracts exhibited 100% effectiveness in the egg hatch inhibition assay, regardless of concentration (50–1.5625 mg/mL). …”
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Genetic inbreeding load and its individual prediction for milk yield in French dairy sheep by Simona Antonios, Silvia T. Rodríguez-Ramilo, Andres Legarra, Jean-Michel Astruc, Luis Varona, Zulma G. Vitezica

“…A fraction of 99.1% of the partial inbreeding coefficients were lower than 0.01 in all breeds, meaning that in practice inbreeding occurs in pedigree loops that span several generations backwards. …”
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