Genomic analysis of the SMN1 gene region in patients with clinically diagnosed spinal muscular atrophy: a retrospective observational study by Tamaki Kato, Mamoru Yokomura, Yutaka Osawa, Kensuke Matsuo, Yuji Kubo, Taihei Homma, Kayoko Saito

“…Three SNVs in intron 6, c.834+1506A>G (n = 9), c.834+1751G>A (n = 2), and c.835-367C>A (n = 5) were identified; all were numerically, and c.834+1506A>G and c.835-367C>A were significantly, more frequent in patients with 0 copies versus those with ≥ 1 copy of exon 7 in SMN1. …”
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Transjugular Intrahepatic Portosystemic Shunt Placement for Portal Hypertension: Meta-Analysis of Safety and Efficacy of 8 mm vs. 10 mm Stents by Jiangtao Liu, Eric Paul Wehrenberg-Klee, Emily D. Bethea, Raul N. Uppot, Kei Yamada, Suvranu Ganguli

“…Meta-analysis results suggest that there is not one superior stent choice for all clinical scenarios and that the TIPS indication of variceal bleeding or refractory ascites might have different appropriate selection of the shunt diameter.…”
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Hubungan Inisiasi Menyusu Dini dengan Kadar Oksitosin dan Involusi Uteri 2 Jam Post Partum di Klinik Bersalin Swasta Kabupaten Padang Pariaman Tahun 2014 by Fatmi Nirmala Sari, Eryati Darwin, Emi Nurjasmi

“…</em></p><p><strong><em>Keywords:</em></strong><em> </em><em>EBF, levels of oxytocin, uterine involution 2 hours postpartum</em><em></em></p></div><em><br clear="all" /> </em>…”
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Maximizing the potential of water buffalo milkability: best practices and lessons learned by Carlo Boselli, Antonio Borghese

“…The differences were the following: better pre-stimulation allowing a positive endogenous release of oxytocin, with reduced lag time; independent milk ejection for each teat, with optimal milking of all quarters, with the reduction of BT; improvement of milking hygiene during milking, limiting the incidence of mastitis and with a low value of somatic cell score; adverse effects due to failed or incomplete milking (17% of the total milkings), limiting the potential capacity and efficiency of AMS; frequent leakage of airflow, which could cause alteration of milk composition. …”
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Influence of sediment additions on the mechanical behavior of fiber-reinforced concrete in aggressive environments by Louafi Goudih, Hamid Sellaf, Benamar Balegh, Ali Meksi, Adda Hadj Mostefa, Mohamed Elamine Dahamni

“…The concrete with DS exhibited lower strength (31.81 MPa) and showed higher resistance to HCl (ML = 38.78%) compared to the MP concrete (ML = 40.74%). Additionally, all concrete samples exhibited good resistance to sulfuric acid due to the formation of expansive ettringite which protected the concrete from further degradation. …”
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Perception, Trust, and Motivation in Consumer Behavior for Organic Food Acquisition: An Exploratory Study by Elena Moroșan, Violeta Popovici, Ioana Andreea Popescu, Adriana Daraban, Oana Karampelas, Liviu Marian Matac, Monica Licu, Andreea Rusu, Larisa-Marina-Elisabeth Chirigiu, Sinziana Opriţescu, Elena Iuliana Ionita, Alina Saulean, Maria Nitescu

“…(1) Background: A sustainable healthy diet assures human well-being in all life stages, protects environmental resources, and preserves biodiversity. …”
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Enhancing Learners’ Engagement and Performance in Learning through E-Resources and Services: National Open University of Nigeria Students as Beneficiaries by Patricia Ngozi Ofodu, Loveth Ogoegbunam Ekwueme

“…The findings from the study revealed that there are some e-resources available for the users’; there are users that are making use of the electronic resources occasionally and daily, while some don’t use e-resources at all. The study also revealed that the use of electronic resources influenced the users’ class tests, assignments, seminar presentations and more, while there was also evidence of non-assistance from the use of e-resources in some students’ learning pursuits. …”
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Snow depth estimation on leadless landfast ice using Cryo2Ice satellite observations by M. Saha, J. Stroeve, J. Stroeve, D. Isleifson, J. Yackel, V. Nandan, V. Nandan, J. C. Landy, H. M. Lam

“…Both the absolute mean snow depths and distributions retrieved from Cryo2Ice were slightly underestimated (2 to 4 cm) when compared to in situ measurements. All four in situ sites had snow with saline basal layers and different levels of roughness and ridging, which significantly impact the accuracy of the Cryo2Ice snow depth retrievals. …”
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Reduced frontotemporal connectivity during a verbal fluency task in patients with anxiety, sleep, and major depressive disorders by Fanxi Ding, Yiyang Ying, Yuqing Jin, Xuanru Guo, Xuanru Guo, You Xu, Zhenghe Yu, Haiteng Jiang, Haiteng Jiang, Haiteng Jiang

“…Therefore, this study combined the VFT and the functional near-infrared spectroscopy (fNIRS) to investigate the neural mechanisms underlying the impairment of executive function across psychiatric disorders including anxiety disorder (AD), sleep disorder (SD) and major depressive disorder (MDD).MethodsTwo hundred and eight participants were enrolled including 52 AD, 52 SD, 52 MDD and 52 healthy controls (HCs). All participants completed the VFT while being monitored using fNIRS to measure changes in brain oxygenated hemoglobin (Oxy-Hb).ResultsOur results demonstrated that MDD, AD and SD exhibited decreased overall connectivity strength, as well as reduced connected networks involving the frontal and temporal regions during the VFT comparing to HC. …”
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A developed TaqMan probe-based qPCR was used to quantify the distribution of AMDV in various tissues of infected mink and its prevalence in northern China by Zaixing Yang, Zaixing Yang, Yifan Li, Yuxuan Jiang, Yuxuan Jiang, Jingqi Wu, Zhenhong Guan, Junwei Ge, Lili Zhao

“…Tissue distribution analysis showed that viral loads were generally high in all organs, especially in the mesenteric lymph nodes and spleen, and the virus was also detected in non-lymphoid tissues such as the brain, confirming the widespread distribution of AMDV throughout the body of mink. …”
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Association between HOMA2 based beta-cell function or insulin resistance and long-term outcomes in kidney transplant recipients with type 2 diabetes by Mehdi Maanaoui, Florence Debillon, Rémi Lenain, Frédérique Defrance, Marie-Christine Vantyghem, Marine Van Triempont, François Provôt, Mikael Chetboun, Julie Kerr-Conte, Aghiles Hamroun, Marie Frimat, Violeta Raverdy, François Pattou, Marc Hazzan, François Glowacki

“…We conducted a monocentric retrospective study at the University Hospital of Lille, including all consecutive adult T2D patients who underwent kidney transplantation between January 2007 and December 2018. …”
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PDE4 and Epac1 Synergistically Promote Rectal Carcinoma via the cAMP Pathway by Xiangyu Kong, Ganghao Ai, Dai Wang, Renzhen Chen, Dongbei Guo, Youliang Yao, Kai Wang, Guiye Liang, Fengjie Qi, Wenzhi Liu, Yongxing Zhang

“…Correlations between PDE4 and Epac1, PDE4 and Cx43, PDE4 and cyclin E1, and Epac1 and Cx43 were observed (all P<0.05). There was no correlation between the other protein pairs examined (P>0.05). …”
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Improving Mechanical Performance of Hybrid Polymer Composites: Incorporating Banana Stem Leaf and Jute Fibers with Tamarind Shell Powder by Karuppusamy Manickaraj, Aruchamy Karthik, Sivasubramanian Palanisamy, Manivannan Jayamani, Syed Kashif Ali, Subramanian Lakshmi Sankar, Saleh A. Al-Farraj

“…These results highlight significant improvements in all three properties, as the proportion of jute in the composite increased and the proportion of banana stem leaves decreased. …”
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Tobacco Use, Risk Perceptions, and Characteristics of Adults Who Used a Heated Tobacco Product (IQOS) in the United States: Cross-Sectional Survey Study by Hui G Cheng, Brendan Noggle, Andrea R Vansickel, Edward G Largo, Pierpaolo Magnani

“…Among those currently using THS who were still smoking (n=298), 249 (83.6%) smoked fewer cigarettes compared with before first trying THS; 362 of 688 (52.6%) AUIs reported having no physical health conditions evaluated in this study and almost three-quarters reported having no mental health conditions. Among all AUIs, over 563 (81.8%) had never used a cessation treatment or had not used it in the past 12 months, and 555 (80.7%) AUIs demonstrated a correct understanding of the MRTP message and AUIs perceived THS as having a lower risk than cigarettes (43.8 vs 64.4 on a 100-point composite score scale). …”
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IDH-mutant gliomas in children and adolescents - from biology to clinical trials by Louise Evans, Sarah Trinder, Sarah Trinder, Andrew Dodgshun, Andrew Dodgshun, David D. Eisenstat, David D. Eisenstat, David D. Eisenstat, James R. Whittle, James R. Whittle, James R. Whittle, Jordan R. Hansford, Jordan R. Hansford, Jordan R. Hansford, Santosh Valvi, Santosh Valvi, Santosh Valvi

“…Gliomas account for nearly 30% of all primary central nervous system (CNS) tumors in children and adolescents and young adults (AYA), contributing to significant morbidity and mortality. …”
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Health benefits of pedestrian and cyclist commuting: evidence from the Scottish Longitudinal Study by Paul Kelly, David Walsh, Bruce Whyte, Zhiqiang Feng, Chris Dibben, Graham Baker, Ruth Dundas, Evangelia Demou, Catherine Friel

“…Cox proportional hazard models were used to compare cyclist and pedestrian commuters with non-active commuters for a range of health outcomes, controlling for pre-existing health conditions, and demographic and socioeconomic characteristics.Results Compared with non-active commuting, cyclist commuting was associated with lower all-cause mortality risk (HR 0.53, 95% CI 0.38 to 0.73), lower risk of any hospitalisation (HR 0.90, 95% CI 0.84 to 0.97), lower risk of cardiovascular disease (CVD) hospitalisation (HR 0.76, 95% CI 0.64 to 0.91) and of having a CVD prescription (HR 0.70, 95% CI 0.63 to 0.78), lower risk of cancer mortality (HR 0.49, 95% CI 0.30 to 0.82) and cancer hospitalisation (HR 0.76, 95% CI 0.59 to 0.98), and lower risk of having a prescription for mental health problems (HR 0.80, 95% CI 0.73 to 0.89). …”
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Assessment of Atrial Conduction Times in Patients with Newly Diagnosed Parkinson’s Disease by Yiğit Çanga, Ayşe Emre, Gülbün Asuman Yüksel, Mehmet Baran Karataş, Nizamettin Selçuk Yelgeç, Ufuk Gürkan, Ali Nazmi Çalık, Hülya Tireli, Sait Terzi

“…PWD, PAs, PAl, and PAt durations were significantly prolonged in the PD group (all p<0.001). Interatrial, right, and left intra-atrial EMD were also significantly longer in PD patients (p<0.001, p<0.001 and p=0.002, resp.). …”
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Application of refined nursing management in complete denture prosthodontics for elderly patients with low and flat alveolar ridge (精细化护理在牙槽嵴低平老年患者全口义齿修复中的作用)... by TANG Youjia (汤有佳), YAN Tong (晏桐), CAI Wen (蔡文), SUN Yu (孙雨), LU Jinxin (卢金鑫)

“…Methods The clinical data of 44 elderly patients with low and flat alveolar ridge requiring complete denture prosthodontics were retrospectively analyzed. All patients received the refined nursing management after admission. …”
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Unlocking barriers and strategies of halal certification for micro and small enterprises in Indonesia: Analytic network process approach by Muhammad Anwar Fathoni, Prima Dwi Priyatno, Faizi, Fadhli Suko Wiryanto, Widarto Rachbini, Suryani

“…We also extend our appreciation to all the respondents and participants who contributed valuable insights and data for this study, as well as to the institutions involved for their support and collaboration.…”
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Factors Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes Mellitus by Bin-Bin He, Li Wei, Yun-Juan Gu, Jun-Feng Han, Ming Li, Yu-Xiang Liu, Yu-Qian Bao, Wei-Ping Jia

“…Methods. 2009 patients with T2DM were included in this cross-sectional study. All patients underwent eye examination, and the DR stage was defined by an ophthalmologist. …”
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