The landscape of immunogenic cell death-related genes predicts the overall survival and immune infiltration status of non-small-cell lung carcinoma by Jian Zhang, Huiying Li, Xi Zhang, Yue Yang, Yue Sun

“…Background: Non-small cell lung cancer (NSCLC), which accounts for about 85 % of all lung cancers, currently exhibits insensitivity to most treatment regimens. …”
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Evaluating the Effectiveness of InsightApp for Anxiety, Valued Action, and Psychological Resilience: Longitudinal Randomized Controlled Trial by Victoria Amo, Falk Lieder

“…On one hand, we found no significant posttest scores on mental health and well-being measures directly after the intervention or 7 days later (all P>.22). In contrast, when confronted with real-life stress, the treatment group experienced a 15% lower increase in anxiety (1-tailed t test, t197=–2.4; P=.009) and a 12% lower increase in the struggle with anxiety (t197=–1.87; P=.031) than the control group. …”
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Diversity in mitotic DNA repair efficiencies between commercial inbred maize lines and native Central American purple landraces by Carlos Víquez-Zamora, Sergio Castro-Pacheco, María Viñas, Pablo Bolaños-Villegas

“…Results Single-cell electrophoresis results of statistical significance suggested that the landrace P1-Pujagua Santa Cruz is resistant to damage caused by the radiomimetic agent Zeocin, and landrace P2-Pujagua La Cruz was able to repair all DNA damage after 24 h of treatment and 1 h of recovery time. …”
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Transformers for Neuroimage Segmentation: Scoping Review by Maya Iratni, Amira Abdullah, Mariam Aldhaheri, Omar Elharrouss, Alaa Abd-alrazaq, Zahiriddin Rustamov, Nazar Zaki, Rafat Damseh

“…ResultsOf the 1246 publications identified, 67 (5.38%) met the inclusion criteria. Half of all included studies were published in 2022, and more than two-thirds used transformers for segmenting brain tumors. …”
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Increasing Access to Mental Health Supports for 18- to 25-Year-Old Indigenous Youth With the JoyPop Mobile Mental Health App: Study Protocol for a Randomized Controlled Trial by Angela MacIsaac, Teagan Neufeld, Ishaq Malik, Elaine Toombs, Janine V Olthuis, Fred Schmidt, Crystal Dunning, Kristine Stasiuk, Tina Bobinski, Arto Ohinmaa, Sherry H Stewart, Amanda S Newton, Aislin R Mushquash

“…MethodsThe study is a pragmatic, parallel-arm randomized controlled superiority trial design spanning a 4-week period. All participants will receive UP, which involves waitlist monitoring practices at the study site, which includes regular check-in phone calls to obtain any updates regarding functioning. …”
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The Closer, The Harder? Investigating the use of peripheral vision in 3vs3 counter-attack VR situations in football by Božo Vukojević, Svitlana Pinchuk, Christian Vater

“…Results: The results showed that fixation distance significantly increased with direct opponent distance, F(1.585, 53.889) = 181.428, p < .001, η²p = 0.842, with significant differences between all distances (p< .001). Gaze behavior differed markedly between monitoring and execution phases F(1, 34) = 49.194, p < .001, η²p = 0.591. …”
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Benefits and Risks of Clopidogrel vs. Aspirin Monotherapy after Recent Ischemic Stroke: A Systematic Review and Meta-Analysis by Maurizio Paciaroni, Birsen Ince, Bo Hu, Jiann-Shing Jeng, Kursad Kutluk, Liping Liu, Min Lou, Vladimir Parfenov, Ka Sing Lawrence Wong, Babak Zamani, Dara Paek, Jung Min Han, Michael del Aguila, Shalini Girotra

“…There was no difference in the rate of all-cause mortality between the two groups. Conclusions. …”
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Associations of Sociodemographic Characteristics with Food Choice Motives’ Importance Among Mexican Adults: A Cross-Sectional Analysis by Miguel Amaury Salas-García, María Fernanda Bernal-Orozco, Andrés Díaz-López, Alejandra Betancourt-Núñez, Pablo Alejandro Nava-Amante, Barbara Vizmanos

“…Higher relative importance of convenience, price, and image management (all, <i>p</i> < 0.05) were associated with men. …”
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Effects of sexual counseling and education based on self-efficacy theory on the sexual function of women with breast cancer by Azadeh Jamshidi, Farzaneh Noroozi, Razieh Bagherzadeh, Tayebeh Gharibi

“…Descriptive statistics (mean, standard deviation, percentage, frequency) and analytical tests, including the independent t-test, Mann‒Whitney U test, Chi-square test, and Fisher’s exact test and repeated-measures analysis of variance (ANOVA) followed by post hoc LSD test were used for data analysis, considering a significance level of less than 0.05 in all cases. Result The mean age of patients in the intervention and control groups was 44.42 ± 4.88 and 43.44 ± 5.20, respectively. …”
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Integrative application of licorice root extract and melatonin improves faba bean growth and production in Cd-contaminated saline soil by Shimaa A. Abd El Mageed, Ali A. S. Sayed, Ahmed Shaaban, Khaulood A. Hemida, Abdelsattar Abdelkhalik, Wael M. Semida, Ibrahim A. A. Mohamed, Mohammed A. H. Gyushi, Yasmine H. Abd Elmohsen, Taia A. Abd El Mageed

“…Application of LRE + Mt significantly reduced hydrogen peroxide (H2O2) accumulation, lipid peroxidation and Cd content in leaves and seeds, all of which had increased due to Cd stress. Application of LRE + Mt significantly mitigated the Cd-induced oxidative damage by increasing the activity of reactive oxygen species (ROS) scavenging enzymes such as superoxide dismutase, catalase, ascorbate peroxidase, and glutathione reductase, in parallel with enhanced ascorbate and reducing glutathione content. …”
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Health Care Professionals and Data Scientists’ Perspectives on a Machine Learning System to Anticipate and Manage the Risk of Decompensation From Patients With Heart Failure: Quali... by Joana Seringa, Anna Hirata, Ana Rita Pedro, Rui Santana, Teresa Magalhães

“…Ethical approval was granted by the NOVA National School of Public Health ethics committee (CEENSP 14/2022), and informed consent was obtained from all participants. ResultsThe participants recognized the potential benefits of ML models for early detection, risk stratification, and personalized care of patients with HF. …”
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Comparative CT with stress manoeuvres for diagnosing distal isolated tibiofibular syndesmotic injury in acute ankle sprain: a protocol for an accuracy- test prospective study by João Carlos Rodrigues, Mario Lenza, Laercio Alberto Rosemberg, Durval do Carmo Santos Barros, Mario Ferretti, Alexandre Leme Godoy Santos, Marcelo Pires Prado, José Felipe Marion Alloza, Renato Amaral Masagão, Adham do Amaral e Castro, Marco Kawamura Demange

“…Sensitivity, specificity, area under the receiver operating characteristic curve and likelihood analyses will compare the diagnostic accuracies of the strategies.Ethics and dissemination The Internal Review Board and the Einstein Ethics Committee approved this study (registered number 62100016.5.0000.0071). All participants will receive an oral description of the study’s aim, and the choice to participate will be free and voluntary. …”
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Feasibility of fetal cardiac function and anatomy assessment by real-time spiral balanced steady-state free precession magnetic resonance imaging at 0.55T by Ye Tian, Jon Detterich, Jay D. Pruetz, Ecrin Yagiz, John C. Wood, Krishna S. Nayak

“…The proposed sequence enabled evaluation of the fetal heart in <30 min in all cases (average 22 min). Real-time MRI allowed easy adjustment of scan plan, automatic whole-heart volumetric sweeping, and flexible choice of reconstruction temporal resolution. …”
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Telomerase inhibiting phytochemicals derived from Blumea eriantha for cancer treatment: A comprehensive computational analysis by Rahil Ummar Faruk Abbu, Shaik Mohammad Abdul Fayaz, Divyashree M S, Raghu Chandrashekhar H, Prasanna Kumar Reddy Gayam, Archana Mahadev Rao

“…The phytochemical also exhibited a robust binding affinity mediated by consistent magnesium metal ion interactions involving key residues such as Asp251, Asp252, Ile252, and Asp343, along with additional hydrogen bonding and water-mediated contacts that enhance its stability and selectivity. Furthermore, all the phytochemicals, except Quassimarin, demonstrated various drug-like ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) parameters and validated Lipinski's rule of five, Veber, and Egan drug-likeness rules. …”
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Tumor-associated neutrophils and macrophages interaction contributes to intrahepatic cholangiocarcinoma progression by activating STAT3 by Jian Zhou, Jia Fan, Zhiqiang Hu, Jia Li, Zhengjun Zhou, Pengcheng Wang, Rongqi Sun, Haoyang Xin, Chubin Luo, Shaolai Zhou

“…In tumor samples from patients with ICC, increased TAN and TAM levels were correlated with elevated p-STAT3 expression. All three of those factors were independent predictors of patient outcomes.Conclusions TANs and TAMs interact to promote ICC progression by activating STAT3.…”
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Anti-inflammatory treatment using alpha melanocyte stimulating hormone (α-MSH) does not alter osteoblasts differentiation and fracture healing by Johanna Graue, Melanie Timmen, Katharina Schmitz, Daniel Kronenberg, Markus Böhm, Kishor K. Sivaraj, M. Gabriele Bixel, Richard Stange

“…Results α-MSH-treatment did not impair either proliferation nor mineralisation of osteoblastic cells under native or inflammatory conditions (no significant differences found). All four melanocortin receptor-molecules were expressed in murine osteoblastic cells but in very limited amounts and this did not change upon treatment with inflammatory cytokines or α-MSH or both at the same time. …”
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Analysis of the diagnostic efficacy of ultrasound, MRI, and combined examination in benign and malignant breast tumors by Dianpei Ma, Dianpei Ma, Changliang Wang, Jie Li, Jie Li, Xiaohan Hao, Yun Zhu, Zhizhen Gao, Zhizhen Gao, Chun Liu, Changfan Luo, Yu Huang

“…BackgroundTo compare the diagnostic effectiveness of ultrasound (US), magnetic resonance imaging (MRI), and their combined application in distinguishing between benign and malignant breast tumors, with particular emphasis on evaluating diagnostic performance in different breast densities—fatty breast tissue, where fat predominates, and dense breast tissue, which contains a significant amount of fibroglandular tissue.Materials and methodsA retrospective analysis was conducted on 185 patients with breast tumors, including 90 malignant and 95 benign cases. All patients underwent both US and MRI examinations within one week prior to surgery. …”
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Death trends for 2010 - 2022 for members of a large private medical scheme in South Africa by L Steenkamp, S Collie, T A Moultrie, H Moultrie, G Gray

“…To investigate trends in Discovery Health Medical Scheme (DHMS) members’ death rates and underlying cause of death patterns between 2010 and 2022. Methods. All-cause deaths were compared across years accounting for demographic changes, by analysing age- and sex-standardised rates using 2019 age and sex population weightings. …”
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BananaImageBD: A comprehensive banana image dataset for classification of banana varieties and detection of ripeness stages in BangladeshMendeley Data by Md Hasanul Ferdaus, Rizvee Hassan Prito, Ahmed Abdal Shafi Rasel, Masud Ahmed, Md. Jahid Hassan Saykot, Shanjida Sultan Shanta, Sonali Akter, Ankan Chandra Das, Mohammad Manzurul Islam, Mahamudul Hasan, Md Sawkat Ali

“…Overall, the dataset has 2471 original images of different varieties of bananas and 820 original images of varying ripeness stages of bananas. All the images were carefully captured using a high-quality smartphone camera. …”
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Butyrate attenuates sympathetic activation in rats with chronic heart failure by inhibiting microglial inflammation in the paraventricular n... by Liu Chang, Yu Hao, Xia Hongyi, Wang Ziwei, Li Bolin, Xue Hongmei, Jin Sheng, Xiao Lin, Wu Yuming, Guo Qi

“…The improvements in intestinal barrier function, reductions in microglia-mediated inflammation and decreases in NMDA receptor 1 expression in the PVN are all due to the protective effects of NaB.…”
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