Faricimab efficacy in type 1 macular neovascularization: AI-assisted quantification of pigment epithelium detachment (PED) volume reduction over 12 months in Naïve and switch eyes by Jennifer Cattaneo, Paolo Forte, Giovanni Forte, Chiara M. Eandi

“…Abstract Background This study evaluates the efficacy of intravitreal Faricimab in reducing pigment epithelium detachment (PED) and fluid volumes in both treatment-naïve eyes and eyes unresponsive to anti-VEGF mono-therapies, all diagnosed with type 1 macular neovascularization (T1 MNV) over a period of 12-month. …”
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Corneal and Epithelial Thickness Mapping: Comparison of Swept-Source- and Spectral-Domain-Optical Coherence Tomography by Cristina Georgeon, Ilanite Marciano, Roxane Cuyaubère, Otman Sandali, Nacim Bouheraoua, Vincent Borderie

“…Interoperator variability (standard deviation and COV) was significantly higher for SS-OCT than for SD-OCT for all local epithelial thicknesses and significantly lower for the central CT and several local corneal thicknesses, whereas no significant differences between both technologies were found for the central and minimum ET and the minimum CT. …”
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Circulating, Extracellular Vesicle-Associated Tissue Factor in Cancer Patients with and without Venous Thromboembolism by Valentina Lami, Dario Nieri, Marta Pagnini, Mario Gattini, Claudia Donati, Mariella De Santis, Alessandro Cipriano, Erica Bazzan, Andrea Sbrana, Alessandro Celi, Tommaso Neri

“…The final population included 68 patients (U-VTE: <i>n</i> = 15; C-VTE: <i>n</i> = 24; C-w/o VTE: <i>n</i> = 29). All patients with VTE were enrolled within 48 h of diagnosis; non-VTE patients were recruited in the oncologic outpatient services. …”
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Circulating Tumor DNA Detection for Recurrence Monitoring of Stage I Non‐Small Cell Lung Cancer Treated With Microwave Ablation by Lin Cheng, Sheng Xu, Yu‐feng Wang, Sheng‐wei Li, Bin Li, Xiao‐Guang Li

“…Methods We recruited 43 patients with inoperative stage I NSCLC, all of whom underwent biopsy‐synchronous microwave ablation (MWA). …”
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Radiotherapy for Oligometastases and Oligo-Recurrence of Bone in Prostate Cancer by Ken-ichi Tabata, Yuzuru Niibe, Takefumi Satoh, Hideyasu Tsumura, Masaomi Ikeda, Satoru Minamida, Tetsuo Fujita, Daisuke Ishii, Masatsugu Iwamura, Kazushige Hayakawa, Shiro Baba

“…The 3-year overall survival rates for all patients, for patients that received a radiotherapy dose of ≥40 Gy (𝑛=21) and for those that received <40 Gy (𝑛=14), were 77.2%, 90.5%, and 50.0%, respectively. …”
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Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening by Georgina L Hollitt, Mark M Hassall, Owen M Siggs, Jamie E Craig, Emmanuelle Souzeau

“…The cohort was highly educated (42% university education), all were European and 50% were female. Numeracy (mean 2.1 ± 0.9, range 0 to 3), graph literacy (mean 2.8 ± 0.8, range 0 to 4) and genetic literacy (mean 24.2 ± 6.2, range − 20 to + 46) showed a range of levels. …”
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Extended Renal Artery Denervation Is Associated with Artery Wall Lesions and Acute Systemic and Pulmonary Hemodynamic Changes: A Sham-Controlled Experimental Study by Aleksandr D. Vakhrushev, Heber Ivan Condori Leandro, Natalia S. Goncharova, Lev E. Korobchenko, Lubov B. Mitrofanova, Dmitry S. Lebedev, Evgeny N. Mikhaylov

“…In the RDN group, radiofrequency ablation was performed in all available arteries and their segments. An autopsy study of the renal arteries was carried out in both groups. …”
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Entrepreneurial agility and organizational performance of IT firms: A mediated moderation model by Leul Girma Haylemariam, Stephen Oduro, Zewdu Lake Tegegne

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Studying formation of <I>Pseudomonas aeruginosa</I> biofilms grown under different cultivation conditions by T. E. Mironova, V. S. Сherepushkina, V. N. Afonyushkin, N. V. Davydova, V. Yu. Koptev, A. S. Dimova

“…As the research demonstrates, all these factors influence biofilm formation; and a P. aeruginosa growth phase before inoculation is a determining factor in the biofilm formation. …”
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Bacterial contamination in public transport during COVID-19 pandemic: Characterization of an unusual Staphylococcus aureus isolate tolerant to vancomycin by Eva Smelikova, Marcela Krutova, Vaclav Capek, Marie Brajerova, Pavel Drevinek, Jan Tkadlec

“…Staphylococcus aureus isolates exhibiting inconclusive results of vancomycin susceptibility testing were retested by broth macrodilution and subjected to whole genome sequencing. All S. aureus isolates were tested for vancomycin heteroresistance (hVISA). …”
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Waste processing techniques at the landfill site using the material flow analysis method by B. Ratnawati, M. Yani, S. Suprihatin, H. Hardjomidjojo

“…Four prospective scenarios were identified: 1) waste processing with composting; 2) composting and reuse, reduction, and recycling; 3) waste to energy; and 4) the combined process of scenarios 1 – 3. All treatments carried out can reduce leachate by 5.09 – 14.32 per cent, emissions of 11.31 – 44.48 per cent, waste 14.13 – 65.97 tons/day in the landfill, and can extend the service life of the landfill by 3 – 14 years.CONCLUSION:  Material flow analysis was used to calculate the waste processing, emission rate, and leachate production from the four processing scenarios. …”
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Frequency of Physical Activity-Related Injuries Among Adolescents: An Umbrella Review by Kerttu Toivo, Peter Bakalár, Mari Leppänen, Jari Parkkari, Jari Parkkari, Ensar Abazović, Boštjan Šimunič, Kaja Teraž, Kaja Teraž, Marta Malinowska-Cieślik, Jaroslava Kopčáková, Aurel Zelko, Aurel Zelko, Aurel Zelko, Agnieszka Michalska, Dagmar Sigmundová, Rado Pišot, Armin Paravlić, Armin Paravlić

“…We were not able to pool data from reviews and conduct meta-analysis due to heterogeneity of injury definitions, exposure times, and sample demographics. All reviews included studies of injuries sustained in organized sports, and injury incidence was higher during matches than training. …”
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Research on extrusion welding of dissimilar magnesium alloys: Mg–Al–Zn and Mg–Gd by Jieyu Li, Shengwen Bai, Zhihua Dong, Yan Yang, Jiangfeng Song, Weijun He, Guangsheng Huang, Bin Jiang

“…The findings revealed that, as the extrusion temperature increased, the shear strength of all three types of sheets first increased and then decreased. …”
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Digital interactive experience- and game-based fall interventions for community-dwelling healthy older adults: a cross-disciplinary systematic review by Celina Ciemer, Celina Ciemer, Lisa Kröper, Thomas Jürgen Klotzbier, Sabiha Ghellal, Nadja Schott

“…Among included articles, most aspects incorporated both HMS and UXG across all four categories: O(n = 37), D(n = 37), T(n = 54), and E(n = 21).ConclusionThe review underscores the importance of digital interactive experience- and game-based fall prevention interventions. …”
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An experimental and numerical study of the ballistic behavior of an epoxy matrix hybrid composite reinforced with aramid fabric and fique fabric by Bernardo Soares Avila de Cêa, Raí Felipe Pereira Junio, Douglas Santos Silva, Fábio da Costa Garcia Filho, Sergio Neves Monteiro, Lucio Fabio Cassiano Nascimento

“…The Contact Force graph allowed observing all the interaction that occurred between the projectile and the test specimen, with the greatest acting force of 6794.7 N, until the moment in which the interaction between the bodies is considered null.…”
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Laboratory Study of Local Scour Around an Array of Pile Groups in Clear-Water Scour Conditions by Ming Gong, Xinying Pan, Shengtao Du, Guoxiang Wu, Yingxue Lv, Yunjia Sun, Guangjia Ding, Bingchen Liang

“…The pile-to-pile space was five times the diameter of a single pile. All the tests were in clear-water scour conditions. …”
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The “real life” efficacy of dupilumab is independent of initial polyp size and concomitant steroids in CRSwNP by Nicholas J. Campion, Jonas Brugger, Aldine Tu, Victoria Stanek, Faris F. Brkic, Tina J. Bartosik, David T. Liu, Bruna S. Hoehl, Katharina Gangl, Julia Eckl-Dorna, Sven Schneider

“…Methods 97 patients with CRSwNP, who were begun on dupilumab between January 2020 and October 2021, were included. All patients were followed-up for 6 months. At each visit they underwent nasal endoscopy, smell identification tests and filled out validated patient questionnaires. …”
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Comparison of diet and exercise on cardiometabolic factors in young adults with overweight/obesity: multiomics analysis and gut microbiota prediction, a randomized controlled trial by Zongyu Lin, Tianze Li, Fenglian Huang, Miao Wu, Lewei Zhu, Yueqin Zhou, Ying‐An Ming, Zhijun Lu, Wei Peng, Fei Gao, Yanna Zhu

“…Notably, the FR group further reduced low‐density lipoprotein (LDL‐C) and uric acid (UA) (all p < 0.05). Mediation analysis revealed four gut microbiota–metabolite–host axes in improving CMFs. …”
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Efficacy of Esophageal Protector in Treating Gastroesophageal Reflux Disease with Extraesophageal Symptoms: a Multicenter, Open-Label, Observational Study by Yu. A. Kucheryavy, D. N. Andreyev, E. Yu. Eryomina, A. A. Gilmanov, O. V. Nazarova, Ye. A. Sidneva, Yu. G. Topalova

“…When analyzing the dynamics of individual indicators of the RSI scale before and after treatment, a significant regression in the severity of all symptoms of the disease was noted. In addition, the results showed that the proportion of patients taking antacid-containing drugs at visit 1 significantly decreased from 58.2 % (95 % CI: 54.0–62.4) to 15.2 % (95 % CI: 12.1–18.3) by visit 2. …”
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Effects of Renal Denervation via Renal Artery Adventitial Cryoablation on Atrial Fibrillation and Cardiac Neural Remodeling by Wei Wang, Zhaolei Jiang, Rongxin Lu, Hao Liu, Nan Ma, Jie Cai, Min Tang, Ju Mei

“…After LA burst pacing, all 10 canines (100%) could be induced AF in the Sham group, but only 4 of 10 canines (40%) could be induced AF in the LRDN group (P=0.011). …”
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