Dose‐exposure‐response of CARDALIS® (benazepril/spironolactone) on the classical and alternative arms of the renin‐angiotensin‐aldosterone system in healthy dogs by Elizabeth Manson, Jessica L. Ward, Maria Merodio, Emilie Guillot, Thomas Blondel, Karin Allenspach, Oliver Domenig, Jonathan P. Mochel

“…CARDALIS® was well‐tolerated at all doses with no clinically relevant changes in renal values or serum electrolytes. …”
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Comparison of Brain Activation Between Different Modes of Motor Acquisition: A Functional Near‐Infrared Study by Meng‐Hsuan Tsou, Pei‐Yun Chen, Yi‐Ting Hung, Yong‐Wei Lim, Shiuan‐Ling Huang, Yan‐Ci Liu

“…MI and MVF induced greater activity in the PMC and SMA, and MVF showed significant activity in all brain areas, especially in the bilateral M1. …”
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Association between deep gray matter iron deposition and clinical symptoms in Parkinson’s disease: a quantitative susceptibility mapping study by Hui Zhao, Hui Zhao, Qiu-Hong Ji, Zhong-Zheng Jia, Li-Hua Shen

“…Further comparisons indicated that the MSVs of the SN, PT, GP and CN are all higher in advanced stages than in early stages. …”
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Laguna de fracasos by Lagunaries

“…We inhabit the irony of a virtuality that imposes a distance on us and at the same time it hacks all geographical borders. A practice that does not yet have a name, a performance that is always provisional, weaving voices and actions through listening and activating our own and other people’s writings. …”
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Simulation of Fire Emergency Evacuation in a Primary School Based on Pathfinder Software by Mahdi Safari, Reza Afkhami, Mohammad Amerzadeh, Vida Zaroushani

“…Notably, the RSET consistently exceeded the ASET (180 s) across all simulations. (4) Conclusions: This research deepens our understanding of school evacuation dynamics and underscores the need for improved architectural designs and safety protocols to protect vulnerable populations, especially children. …”
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Whole transcriptome analysis of unmutated sporadic ALS patients' peripheral blood reveals phenotype-specific gene expression signature by Francesca Dragoni, Maria Garofalo, Rosalinda Di Gerlando, Bartolo Rizzo, Matteo Bordoni, Eveljn Scarian, Camilla Viola, Veronica Bettoni, Giuseppe Fiamingo, Danilo Tornabene, Lucia Scanu, Orietta Pansarasa, Luca Diamanti, Stella Gagliardi

“…Interestingly, only one gene (Y3_RNA, a misc_RNA component of the Ro60 ribonucleoprotein involved in cellular response to interferon-alpha) was upregulated at different levels across all phenotypes, whereas other genes appeared phenotype-specific. …”
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Association of pre-exiting heart failure with long-term mortality and the recurrence of sepsis by Jin-Wen Zhu, Xiu-Ping Hu, Jun Jin, Bai Xu, Run Zhang, Sen Ye, Fang-Xiao Gong, Jun Hong, Qian Li, Xiang-Hong Yang, Ren-Hua Sun

“…A total of 16,092 sepsis patients without a history of heart failure and 841 sepsis patients with pre-existing heart failure were identified from the Medical Information Mart for Intensive Care version IV (MIMIC-IV ) database. All patients were adults admitted to intensive care units, and no specific interventions were applied. …”
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Efficacy of Health Literacy Interventions for Caregivers of Individuals with Neurodevelopmental and Chronic Conditions: A Rapid Review by Thom Nevill, Jessica Keeley, Susan Hunt, Rachel Skoss, Olivia Lindly, Jenny Downs, Amanda Marie Blackmore

“…Studies were eligible for inclusion if they reported the efficacy of any intervention aimed at improving the HL of caregivers of individuals with a neurodevelopmental disorder or chronic condition and assessed caregiver HL. All original intervention study designs were eligible, as were systematic reviews. …”
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Cost-utility analysis of combination medical therapies in chronic coronary syndrome: a comparative study using real-world and patient-level data from Iran by Fatemeh Soleymani, Parham Sadeghipour, Majid Davari, Abbas Kebriaeezadeh, Behzad Fatemi, Mohammad Reza Maracy, Nasim Naderi, Saman Zartab

“…Numbers entering and completing the study were reported, with clear definitions of selection, entry and exclusion criteria.Interventions All combinations of recommended medical therapies for CCS were permitted. …”
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Dataset of shotgun metagenomic evaluation of Sorghum bicolor rhizosphere microbiome in soils preceded by Glycine maxNCBINCBINCBINCBI by Olubukola Oluranti Babalola, Ben Jesuorsemwen Enagbonma

“…Actinomycetota and Function unknown dominated the microbiomes across all cropping systems. The insights gained from this dataset hold promise for advancing sustainable agricultural practices, particularly through optimizing crop rotations, developing microbial bioinoculants, and enhancing soil health. …”
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Daily Assistance for Amyotrophic Lateral Sclerosis Patients Based on a Wearable Multimodal Brain-Computer Interface Mouse by Ya Jiang, Kendi Li, Yuankai Liang, Di Chen, Mingkui Tan, Yuanqing Li

“…In total, 15 patients with upper extremity limitations performed the mouse system task and 9 patients with lower extremity mobility issues performed the wheelchair system task. To our satisfaction, all the participants fully accomplished the tasks and average accuracies of 83.9% and 87.0% for the two tasks were achieved. …”
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NURSES AND PAIN MANAGEMENT IN TERRITORIAL HEALTH EMERGENCIES: A RETROSPECTIVE STUDY by Federico Pecetta, Gian Domenico Giusti, Sara Staffaroni, Matteo Ricci

“…According to the latest guidelines, it is essential to ensure proper and effective pain management for all patients experiencing pain. Inadequate pain management can result in complications such as delayed recovery and increased patient distress. …”
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Prevalence and factors associated with depression and anxiety among patients recovered from COVID-19: a cross-sectional study in a tertiary care hospital in Nepal by Biraj Man Karmacharya, Kamal Gautam, Kalpana Chaudhary, Prasanna Rai, Shalik Ram Dhital, Shrinkhala Shrestha, Bandana Paneru, Akina Shrestha

“…Introduction COVID-19 has immensely affected the mental health of all people with prominent effects among the COVID-19 survivors who underwent hospitalisation. …”
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Effects of potassium sodium niobate (KNN) thickness on biaxial non-resonant microelectromechanical systems (MEMS) mirror performance by L. Mollard, C. Dieppedale, A. Hamelin, R. Liechti, G. Le Rhun

“…The results obtained with these non-resonant mirrors, all fabricated using a collective 200 mm silicon manufacturing process, exhibit the following: (a) an arm deformation of 50 to 80 <span class="inline-formula">µ</span>m corresponding to an estimated tensile residual stress of approximately 120 MPa in the KNN layer, (b) the same level of performance for the 0.5 <span class="inline-formula">µ</span>m thick lead zirconate titanate (PZT) and KNN at 10 V, and (c) an optical angle up to 8.5° at 40 V for the 2 <span class="inline-formula">×</span> 2 mm<span class="inline-formula">²</span> mirror design with 1.5 <span class="inline-formula">µ</span>m thick KNN. …”
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Surgical planning of small intestine neuroendocrine tumors: the concept of mesenteric tumor deposits by Romain L’Huillier, Gilles Poncet, Arnaud Pasquer, Thomas Walter, Catherine Lombard-Bohas, Valérie Hervieu, Bénédicte Cayot, Pierre-Jean Valette, Helen Cheung, Laurent Milot

“…This was a retrospective observational study, and all patients undergoing surgery for small intestine neuroendocrine tumor between January 2014 and March 2019 were included. …”
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Improving the quality of design calculations of viscous flow in low-flow centrifugal compressor stages by methods of computational fluid dynamics through reasonable application of... by S. V. Kartashev, Yu. V. Kozhukhov

“…For highReynolds turbulence models, at values of y+=25...50 on all friction surfaces of the computational domain in the optimal mode of operation, the grid independence of the solution for the entire gas-dynamic characteristic is ensured. …”
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Diagnostic efficacy and necessity of 18F-FDG PET/CT in fever of unknown origin: insights from a retrospective cohort study by Xiaoman Yu, Shuang Wang, Na Du, Hongguang Zhao, Haiying Chen

“…BackgroundDespite advancements in medical examination equipment and techniques, fever of unknown origin (FUO) remains challenging in internal medicine.PurposeThis study evaluates the diagnostic efficacy and necessity of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in patients with FUO.MethodsWe retrospectively analyzed the results of 18F-FDG PET/CT in a cohort of 284 patients with FUO admitted to the Department of Infection at the First Hospital of Jilin University between January 2018 and March 2024. All patients received a final clinical diagnosis after various treatments, which helped determine the diagnostic relevance of identified lesions using 18F-FDG PET/CT. …”
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Supporting a state in developing a working theory of improvement for promoting equity in science education by William R. Penuel, Tiffany N. Neill, Todd Campbell

“…The team also surfaced several policy changes needed to implement change strategies, only some of which team members felt they had some authority.DiscussionWhere past researchers have observed that equity can disappear as a focus during implementation of reforms, this study found that developing an aim statement and driver diagram helped energize and refocus a team’s implementation efforts geared toward a vision for science teaching and learning that is focused on ensuring all students can engage in meaningful science learning that is culturally and locally relevant to them.…”
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Efficacy and safety of Xiongzhitongluo granules in the treatment of acute ischemic stroke: study protocol for a randomized controlled trial by Yunmeng Chen, Jingjing Wei, Xiao Liang, Yue Liu, Lina Miao, Di Zhao, Yunfan Zhang, Hongxi Liu, Yunling Zhang

“…Written informed consent was obtained from all participants.Clinical trial registrationhttps://clinicaltrials.gov/, identifier, ChiCTR2200061859.…”
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Flowers: precious food and medicine resources by Xuqiang Liu, Senye Wang, Lili Cui, Huihui Zhou, Yuhang Liu, Lijun Meng, Sitan Chen, Xuefeng Xi, Yan Zhang, Wenyi Kang

“…Flower plants are popular all over the world and important sources of ornamental plants, bioactive molecules and nutrients. …”
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