Efficacy and safety of immune checkpoint inhibitors in patients with advanced intrahepatic cholangiocarcinoma by Ziting Peng, Jianhui Dong, Shuyao Tang, Jiaxu Shi, Tongdong Shi

“…However, no significant disparity in the PFS with immunotherapy in different lines therapy(P=0.406) and the OS was observed between the two groups(P=0.360). 18 patients (18.75%) experienced treatment-emergent adverse events (AEs), with 3 patients encountering AEs of grade ≥3. All patients returned to normal after symptomatic treatment.ConclusionsIn patients with advanced ICC, the timely initiation of ICIs as adjuvant therapy following first-line antitumor treatment can result in favorable efficacy and a good safety profile.…”
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Knowledge‐Informed Deep Neural Networks for Solar Flare Forecasting by Ming Li, Yanmei Cui, Bingxian Luo, Xianzhi Ao, Siqing Liu, Jingjing Wang, Shuxin Li, Chenxi Du, Xiaojing Sun, Xin Wang

“…Pure CNN model, Fusion model 1, and Fusion model 2 are built to forecast M‐class or above flares in the next 48 hr, which involve data preprocessing, data preprocessing and sample grouping, and all the three aspects, respectively. Fusion model 2 that augments the most prior knowledge has the best performance. …”
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Satellite-Based Forest Stand Detection Using Artificial Intelligence by Patrik Kovacovic, Rastislav Pirnik, Julia Kafkova, Mario Michalik, Alzbeta Kanalikova, Pavol Kuchar

“…The forest constitutes an essential and irreplaceable component of life for all organisms, with its primary significance lying in its role in creating a breathable atmosphere on Earth. …”
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Patterns of self-harm presentations at a Tertiary Urban Hospital in Kenya: A retrospective 5-year study (2018-2022). by Willie Njoroge, Catherine Gitau, Everline Onchari, Linnet Ongeri, Linda Khakali, Murad Khan, Zul Merali, Lukoye Atwoli, Jasmit Shah

“…A data abstraction tool was used to collect data from eligible files sourced from the medical records department for all patients who met the study criteria. Summary statistics were reported as frequencies and percentages for categorical data and as means and standard deviations for continuous data.…”
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Cross-sectional survey of changes in knowledge, attitudes and practice of mask use in Sydney and Melbourne during the 2020 COVID-19 pandemic by Abrar Ahmad Chughtai, C Raina MacIntyre, Holly Seale, Ashley Lindsay Quigley, Mallory Trent

“…In both Sydney and Melbourne, a consistent decrease was reported in almost all risk-mitigation behaviours between March 2020 and July 2020 and again between March 2020 and September 2020. …”
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Helicobacter pylori infection diagnostics and choice of eradication treatment: results of inquiry of doctors from different regions of Russian Federation by N. N. Dekhnich, R. S. Kozlov, O. A. Sablin, Ye. A. Prischepova

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The use of veno-arterial extra corporeal membrane oxygenation for hemodynamics support during high-risk percutaneous coronary intervention by Wael Samy, Helmy Elghawaby, Akram Abdelbary, Hany Zakaria Mohamed, Alia Hassan Abdel Fattah

“…Also our study showed no statistically difference between LV EF before and after PCI in both groups; in group 1, eight patients had complete revascularization in one session while in group 2 only seven patients had complete revascularization; one patient in group 1 had VT while in group 2, one patient had VF and another one suffered of asystole; group 1 patients all discharged home within 1 week while group 2 had two mortalities during PCI. …”
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Minimally Manipulated Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Systematic Review of Clinical Evidence by B. Di Matteo, F. Vandenbulcke, N. D. Vitale, F. Iacono, K. Ashmore, M. Marcacci, E. Kon

“…The reference lists of all retrieved articles were further reviewed for identification of potentially relevant studies. …”
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Effects of home-based mirror therapy and cognitive therapeutic exercise on the improvement of the upper extremity functions in patients with severe hemiparesis after a stroke: a pr... by Josefa Gonzalez-Santos, Raul Soto-Camara, Paula Rodriguez-Fernández, Maria Jimenez-Barrios, Jeronimo Gonzalez-Bernal, Carla Collazo-Riobo, Maha Jahouh, Yolanda Bravo-Anguiano, Jose M Trejo-Gabriel-Galan

“…To assess the progress of patients who had a stroke in the subacute phase, all variables will be evaluated at different visits: initial (just before starting treatment and 4 weeks post-stroke), post-intervention (6 weeks after initial) and follow-up (6 months).Ethics and dissemination This protocol has been approved by the Institutional Review Board (CEIm-2.134/2.019) and registered at ClinicalTrials.gov (NCT04163666). …”
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Prognostic significance of MRD and its correlation with arsenic concentration in pediatric acute promyelocytic leukemia: a retrospective study by SCCLG-APL group by Zhong Fan, Liang-Chun Yang, Yi-Qiao Chen, Wu-Qing Wan, Dun-Hua Zhou, Hui-Rong Mai, Wan-Li Li, Li-Hua Yang, He-Kui Lan, Hui-Qin Chen, Bi-Yun Guo, Zi-Jun Zhen, Ri-Yang Liu, Guo-Hua Chen, Xiao-Qin Feng, Cong Liang, Li-Na Wang, Yu-Li, Jie-Si Luo, Dan-Ping Huang, Xue-Qun Luo, Bin Li, Li-Bin Huang, Xiao-Li Zhang, Yan-Lai Tang

“…Background: Treatment outcomes for acute promyelocytic leukemia (APL) have improved with all-trans-retinoic acid and arsenic trioxide, yet relapse remains a concern, especially in pediatric patients. …”
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SUGT1 is a prognostic biomarker and is associated with immune infiltrates in ovarian cancer by Linyan Ge, Xiu Liu, Lingyan Zhang, Jiaren Zhang, Guanghui Song

“…Univariate and multivariate Cox regression revealed that SUGT1 could serve as an independent risk factor for prognosis of patients with OC. Conclusions All these results of this study show that SUGT1 is an important molecular component in immune infiltration in OC and may have a new significant prognostic role in OC.…”
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Comparative analysis of galectin-1, galectin-3, and galectin-8 signatures in normal and choriocarcinoma trophoblast cell lines by Jovanović Krivokuća Milica, Legner Janko, Ćujić Danica, Vilotić Aleksandra, Grubiša Ivana, Vićovac Ljiljana, Bojić-Trbojević Žanka

“…Additionally, different splice variants of galectin-8 were detected across all cell lines. Galectin-1 was predominantly localized at the plasma membrane. …”
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Spatial-temporal pattern and driving mechanism of urban land use eco-efficiency in mountainous counties based on multi-source data: a case study of Zhejiang province, China by Li Fan, Lindong Ma, Lindong Ma, Zhongwei Huang

“…The explanatory power of all influencing factors decreased over time. (4) At the local scale, GDP per capita (X5), industrial structure (X6), and fiscal expenditure scale (X7) presented positive effects on ULUEE, and development vitality (X9) presented a negative effect. …”
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A 16-week randomized controlled trial of a fish oil and whey protein-derived supplement to improve physical performance in older adults losing autonomy-A pilot study. by Anne-Julie Tessier, Julia Lévy-Ndejuru, Audrey Moyen, Marissa Lawson, Marie Lamarche, Joseé A Morais, Amritpal Bhullar, Francis Andriamampionona, Vera C Mazurak, Stéphanie Chevalier

“…Median age was 87 y (77-94 y; 75% women) and gait speed was 0.69 m/s; 55% had low strength, and all performed under 420m on the 6-minute walk test, at baseline. …”
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A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers by Samuel Cykert, Eugenia Eng, Paul Walker, Matthew A. Manning, Linda B. Robertson, Rohan Arya, Nora S. Jones, Dwight E. Heron

“…Conclusion A system‐based intervention tested in five cancer centers reduced racial gaps and improved care for all.…”
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The Impact of Coronavirus Disease 2019 Pandemic on Female Patients Seeking or Undergoing Fertility Treatment in a Single In Vitro Fertilisation Clinic in Greece: An International,... by Konstantina Pappa, Emmanouil M. Xydias, Apostolos C. Ziogas, Kanelina Bimba, Elias Tsakos, Efstratios Kolibianakis

“…A P value lower than 0.05 was considered statistically significant. All analyses were conducted using the SPSS Statistics software. …”
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Multimorbidity patterns and function among adults in low- and middle-income countries: a scoping review by Karina Berner, Quinette A Louw, Eugene Nizeyimana, Diribsa Tsegaye Bedada

“…Mobility limitations, instrumental activities of daily living, self-care and bowel/bladder problems were consistently linked to all pattern domains.Conclusions The limited and geographically skewed body of literature, along with methodological inconsistencies, hampers a comprehensive understanding of multimorbidity patterns and associations with functioning in LMICs. …”
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Public support for smoke-free private indoor and public outdoor areas in the Netherlands: A trend analysis from 2018– 2022 by Nienke W. Boderie, Sabri Ennissay, Wilhelmina IJzelenberg, Frank J. van Lenthe, Jessica Baars, Jasper V. Been

“…In 2022, average support was higher than 65% for all categories of smoke-free places and highest for private cars with children (91%). …”
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Genetic structure and demographic analysis of a true single-population species, Camellia azalea by Ruo-Qiu Wang, Ying Xu, Min Zhang, Gang Hao, Qiang-Min Zhao, Xin-Kai Liu, Xiao-Fei Liu, Bo Yu, Wen-Ju Zhang

“…Abstract Single-population species (SPS) consist of only one natural population and often are at high risk of extinction. Although almost all species must go through this special stage in their evolutionary process, there is little understanding of how SPS survives. …”
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The influence of cultural belonging on social distances in native and international students from the Republic of Moldova / Influența apartenenței culturale asupra distanțelor soc... by RUSNAC Svetlana, KHORY Johnny

“…Furthermore, universities should not only develop superficial internationalization policies, but ensure that all students are involved so that they can contribute to them. …”
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