Mediation of the effect of prenatal maternal smoking on time to natural menopause in daughters by birthweight-for-gestational-age z-score and breastfeeding duration: analysis of tw... by Darina Peycheva, Leah Li, Mary Fewtrell, Richard Silverwood, Rebecca Hardy

“…Abstract Background Prenatal maternal smoking, lower birthweight, and shorter breastfeeding duration have all been associated with an earlier age at menopause in daughters. …”
Get full text

Optimizing in vitro spherulation cues in the fungal pathogen Coccidioides by Christina M. Homer, Elena Ochoa, Mark Voorhies, Anita Sil

“…Coccidioides can infect both immunocompetent and immunocompromised people and can cause a devastating disseminated infection, including meningitis, with 30% mortality despite all currently available treatments. In this work, we tackle one of the current largest technical barriers to studying the fungus Coccidioides: reliably growing its host form in vitro. …”
Get full text

Climate variability, population growth, and globalization impacting food security in Pakistan by Sohail Abbas, Ahtisham Haider, Shazia Kousar, Heli Lu, Siqi Lu, Fang Liu, Huan Li, Changhong Miao, Wanfu Feng, Muhammad Irfan Ahamad, Muhammad Sajid Mehmood, Rana Muhammad Zulqarnain

“…Multivariate Generalized Auto-Regressive Conditional Heteroscedasticity was used to assess the impact of globalization, population growth, and climate variability on food security. All indexed components explained more than 50% of the variance, resulting in a food security eigenvalue of 3.603 with a 0.901 proportion. …”
Get full text

Quality of bread rolls fortified with date fruit pomace: Structure, proximate composition, staling, and sensory evaluation by Alaa Almoumen, Huda Mohamed, Bhawna Sobti, Mutamed Ayyash, Rabih Kamleh, Ali H. Al-Marzouqi, Afaf Kamal-Eldin

“…The differences in the texture and physical parameters of the different bread rolls were significant during four days of storage with all bread rolls becoming smaller and denser. As fibre concentration increased, the bread became heavier with noticeable textural changes such as increased hardness and chewiness. …”
Get full text

Yield and Sensorial and Nutritional Quality of Strawberry (<i>Fragaria</i> × <i>ananassa</i> Duch.) Fruits from Plants Grown Under Different Amounts of Irrigation in Soilless Culti... by Davide Raffaelli, Rohullah Qaderi, Luca Mazzoni, Bruno Mezzetti, Franco Capocasa

“…While the yield for the Francesca cultivar increased by 10% under the stressed WS1 conditions in comparison to the control conditions, water stress in the WS2 treatment caused a strong reduction in yield in all three genotypes. Overall, the findings emphasize the importance of identifying for each new cultivar the most appropriate water regime in order to amplify the quality of the fruit, thus maintaining high production standards and saving water.…”
Get full text

Golden Eagle in Karatau and Chu-Ili Mountains (Kazakhstan) and Assessment of Risks to its Populations from Developing Wind Energy by Igor V. Karyakin, Kirill I. Knizhov, Elvira G. Nikolenko, Elena P. Shnayder, Genriyetta I. Pulikova, Alyona G. Kaptyonkina

“…The Golden Eagle (Aquila chrysaetos) is the largest eagle in Kazakhstan, breeding in almost all mountainous and forested areas of the country. …”
Get full text

Neglected Forearm Fractures and Its Outcome Following Mediolateral Plate Osteosynthesis: A Retrospective Case Series by Sitsabesan Chokkalingam, Ashok T Ramanathan, Gopinath Menon

“…Results: Fracture healing was achieved in all our cases. Functional results were excellent in nine cases and satisfactory in two cases with extended rehabilitation. …”
Get full text

High rate of false positive malaria rapid diagnostic tests in a district hospital in Uganda by Susanne E. Mortazavi, Susanne E. Mortazavi, Allan Lugaajju, Anna-Clara Ivarsson, Sara Karlsson Söbirk, Sara Karlsson Söbirk, Hans Norrgren, Hans Norrgren, Kristina E. M. Persson, Kristina E. M. Persson

“…Demographic information, malaria history, and parasitemia levels were also recorded.ResultsAmong the RDT-positive participants, 48% tested negative by microscopy, and 45% of these were also negative by LAMP, indicating that 20% of all RDT-positive individuals were likely false positives. …”
Get full text

Factors Associated with Gestational Diabetes Mellitus: A Meta-Analysis by Yu Zhang, Cheng-Ming Xiao, Yan Zhang, Qiong Chen, Xiao-Qin Zhang, Xue-Feng Li, Ru-Yue Shao, Yi-Meng Gao

“…Results indicated that maternal age≥25 years (OR: 2.466, 95% CI: (2.121, 2.866)), prepregnancy overweight or obese (OR: 2.637, 95% CI: (1.561, 4.453)), family history of diabetes (FHD) (OR: 2.326, 95% CI: (1.904, 2.843)), history of GDM (OR: 21.137, 95% CI: (8.785, 50.858)), macrosomia (OR: 2.539, 95% CI: (1.612, 4.000)), stillbirth (OR: 2.341, 95% CI: (1.435, 3.819)), premature delivery (OR: 3.013, 95% CI: (1.569, 5.787)), and pregestational smoking (OR: 2.322, 95% CI: (1.359, 3.967)) increased the risk of GDM with all P<0.05, whereas history of congenital anomaly and abortion, and HIV status showed no correlation with GDM (P>0.05). …”
Get full text

Mitigating salinity stress on tomato growth, water regime, gas exchange, and yield with the application of QuitoMax by Leandris Argentel-Martínez, Ofelda Peñuelas-Rubio, Carlos Ávila Amador, Fábio Steiner, Jorge González Aguilera, Jae-Ho Shin, Alan Mario Zuffo, Rafael Felippe Ratke, Paulo Eduardo Teodoro, Ugur Azizoglu

“…QuitoMax contributed positively to all variables and was superior to stress intensity for most of the variables evaluated in the tolerant variety (Amalia), except for stem thickness and the number of flowers per bunch. …”
Get full text

Chasing the Beginning of Reionization in the JWST Era by Christopher Cain, Garett Lopez, Anson D’Aloisio, Julian B. Muñoz, Rolf A. Jansen, Rogier A. Windhorst, Nakul Gangolli

“…However, a majority of observables, spanning several distinct types of observations, prefer a late start. Not all probes agree with this conclusion, hinting at a possible lack of concordance arising from deficiencies in observations and/or theoretical modeling. …”
Get full text

Early, Noninvasive Clinical Indicators of Kidney Prognosis in Primary Nephrotic Syndrome: A Retrospective Exploratory Study by Keiji Fujimoto, Takatoshi Haraguchi, Sho Kumano, Keita Yamazaki, Nobuhiko Miyatake, Kanae Nomura, Kiyotaka Mukai, Kazuaki Okino, Norifumi Hayashi, Hiroki Adachi, Hitoshi Yokoyama, Yasuo Iida, Kengo Furuichi

“…Significant predictors for time to 40% reduction in the eGFR were as follows: an increase in the serum soluble urokinase plasminogen activator receptor (s-suPAR) 2 months after initiating IST (Δs-suPAR (2M); hazard ratio (HR) for every 500 pg/mL increase: 1.36, P=0.006), s-suPAR at 2 months after initiating IST (s-suPAR (2M); HR for every 500 pg/mL increase: 1.13, P=0.015), urinary protein-to-creatinine ratio (u-PCR) (u-PCR (2M); HR for every 1.0 g/gCr increase: 2.94, P=0.003), and urinary liver-type fatty acid-binding protein (u-L-FABP) (u-L-FABP (2M); HR for every 1.0 μg/gCr increase: 1.14, P=0.006). All four factors exhibited high predictive accuracy for cumulative incidence of 40% reduction in the eGFR up to 8 years after initiating IST, with areas under the receiver operating characteristic curve of 0.92 for Δs-suPAR (2M), 0.87 for s-suPAR (2M), 0.93 for u-PCR (2M), and 0.93 for u-L-FABP (2M). …”
Get full text

Experimental evaluation of mechanically stabilized earth walls reinforced with glass fiber reinforced polymer bars embedded in marble waste-sand mixtures by Shabir Hussain, Irshad Ahmad, Irfan Jamil, Fasih Ahmed Khan, Mansoor Ullah, Saif ul Islam, Mudassir Iqbal, R. Nawaz

“…Results show that the large MSE wall model's average-FD decreased by 13 %, 18 %, and 27 %, and average-VS decreased by 21 %, 26 %, and 36 % due to addition of 14 %MP, 28 %MR, and 21 %(MP+MR) to sand (by weight). In all models maximum FD was observed at 0.31 m (z/H = 0.20) from top of the wall, while vertical settlement near the wall facing was observed to be twice as high as in the center of the model. …”
Get full text

Dentin-derived alveolar bone graft for alveolar augmentation: A systematic review by Dedy Agoes Mahendra, Kavanila Bilbalqish, Alexander Patera Nugraha, Arief Cahyanto, Kaushik Sengupta, Kamal Hanna, Asti Meizarini, Ninuk Hariyani

“…From these articles, 21 articles met the inclusion criteria and were included for descriptive analysis. All of the studies indicated low risk of bias. Studies of dentin-derived ABG, which used bone-derived grafts as the control group, have shown significantly higher percentages of new bone formation, gain in vertical and horizontal dimensions, and less reduction in dimensions. …”
Get full text

Dapsone Alters Phenotypical and Functional Properties of Human Neutrophils In Vitro by Sara Rakočević, Vanja Mališ, Ljiljana Kozić, Anđela Dubovina, Marija Drakul, Dejan Bokonjić, Miodrag Čolić, Dušan Mihajlović

“…However, dapsone significantly decreased the induced oxidative burst of neutrophils at all non-cytotoxic concentrations. Additionally, dapsone showed a dose-dependent suppression of NETosis in activated neutrophils. …”
Get full text

Enhancing patient engagement: the influence of an in-consult patient decision aid on shared decision-making for lung tumour radiation – protocol for the randomised trial ‘SDM Lung... by Karina Dahl Steffensen, Signe Timm, Torben Frøstrup Hansen, Thomas Leth Fink, Charlotte Kristiansen, Torben Schjødt Hansen, Rune Slot Thing

“…Secondary outcomes are patient-reported outcomes, quality of life and side effects following treatment.Ethics and dissemination All patients give informed consent to participate. …”
Get full text

VIBE: an R-package for VIsualization of Bulk RNA Expression data for therapeutic targeting and disease stratification by Indu Khatri, Saskia D. van Asten, Leandro F. Moreno, Brandon W. Higgs, Christiaan Klijn, Christiaan Klijn, Francis Blokzijl, Iris C. R. M. Kolder

“…VIBE integrates statistics in all graphics, enabling data-informed decision-making.ConclusionsVIBE facilitates detailed visualization of individual and cohort-level summaries such as concordant or discordant expression of two genes or pathways. …”
Get full text

Investigating the needs and barriers for prevention, control, and treatment of HIV/AIDS in transgender population: a systematic review of literature by Heshmatollah Sofimajidpour, Ghobad Moradi, Hojat Dehghanbanadaki, Marzieh Mahboobi, Mobin Azami, Parisa Khodakhah, Mohammad Aziz Rasouli, Yousef Moradi

“…Material and Methods Original studies (case-control, cohort, cross-sectional), interventional studies, clinical trials, and qualitative studies were included in the review. All international electronic databases, such as PubMed (Medline), Scopus, Web of Sciences, Cochrane, PsycINFO, and Google Scholar (gray literature) were searched from December 1990 to December 2019. …”
Get full text

RETRACTED: Mycosynthesis of Hematite (α-Fe₂O₃) Nanoparticles Using <em>Aspergillus niger</em> and Their Antimicrobial and Photocatalytic Activities by Ebrahim Saied, Salem S. Salem, Abdulaziz A. Al-Askar, Fathy M. Elkady, Amr A. Arishi, Amr H. Hashem

“…The results revealed that all of the studied parameters, as well as their interactions, had a significant impact on the crystallite size. …”
Get full text

Global, regional, and national burden of ischemic heart disease attributable to secondhand smoke from 1990 to 2019 by Xinyue Yang, Zhiqiang Zhang, Jiayi Sun, Wenjuan Zhang

“…Central Asia has the highest ASMR (16 per 100000, 95% uncertainty interval, UI: 12.8–19.4), and Oceania has the highest ASDR (323.2 per 100000, 95% UI: 228.9–443.1 per 100000) in 2019. All sociodemographic index (SDI) category regions showed a decreasing trend in ASMR and ASDR, with the decrease being more obvious in high and high-middle SDI regions. …”
Get full text