Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials by Alejandro Victoria-Escandell, José Santiago Ibañez-Cabellos, Sergio Bañuls-Sánchez de Cutanda, Ester Berenguer-Pascual, Jesús Beltrán-García, Eva García-López, Federico V. Pallardó, José Luis García-Giménez, Antonio Pallarés-Sabater, Ignacio Zarzosa-López, Manuel Monterde

“…MTA-Fillapex was the most cytotoxic oxidative stress inductor and genotoxic material for HDPSCs at longer times in preincubated cell culture medium, and MTA-Angelus was less cytotoxic and genotoxic than AH-Plus and MTA-Fillapex at all times assayed.…”
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Novel thiazolyl-pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation, and molecular docking studies by Tariq Z. Abolibda, Abdel-Aziz A.A. El-Sayed, Basant Farag, Magdi E.A. Zaki, Abdulwahed Alrehaily, Hossein M. Elbadawy, Ahmad A. Al-Shahri, Saleh R. Alsenani, Sobhi M. Gomha

“…Five compounds, namely 8a, 10, 12a, 12b, and 14, exhibited promising anticancer activity with IC50 values of 5.02 ± 1.83, 4.04 ± 1.37, 3.81 ± 1.96, 2.39 ± 0.75, and 3.27 ± 1.13 μM, respectively, all of which were more effective than doxorubicin (IC50 = 6.18 ± 0.29 μM). …”
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Cross-sectional study of cybervictimisation and non-suicidal self-injury among college students in China: a chain mediation effect of emotion dysregulation and social exclusion by Juan Ni, Xiaoli Liao, Liu Xine

“…Mediation effect analysis revealed a chain mediation effect where cybervictimisation influenced NSSI behaviours through the mediating roles of emotion dysregulation and subsequent social exclusion (all p<0.001).Conclusions This study confirms previous research by highlighting the positive relationship between cybervictimisation and NSSI behaviours, and advances the field by identifying a chain mediation effect involving emotion dysregulation and social exclusion among this relationship. …”
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Pursuit on the plane by objects moving away from the trajectory of defending object, with simulation of detection area by A. А. Dubanov, T. V. Ausheev

“…This article describes the model of pursuit of a single target by the method of chasing a group of objects. All objects participating in the pursuit model move with a constant modulo speed. …”
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Second-line drug-resistant TB and associated risk factors in Karakalpakstan, Uzbekistan by S. Moe, I. Azamat, S. Allamuratova, M. Oluya, A. Khristusev, M.L. Rekart, K. Mamitova, G. Bidwell, C. Gomez-Restrepo, B. Kalmuratov, Z. Tigay, N. Parpieva, K. Safaev, N. Sitali, D. Gomez, A. Mikhail, A. Sinha

“…Limited information is available on the prevalence of resistance to bedaquiline, linezolid, and fluoroquinolone, which are key components of the all-oral treatment regimen for rifampicin-resistant TB in Uzbekistan. …”
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Bone marrow lesion and medial meniscus extrusion width changes following arthroscopic partial meniscectomy for medial meniscal flap tears by Hitoshi Sekiya, Kenzo Takatoku, Hitoshi Okami, Yuji Kanaya, Kenta Yanagisawa

“…The occurrence rate of BMLs was higher in the single leaf and subtotal meniscectomy groups post-surgery, but declined across all groups by 12 months. Among the three groups with different resection patterns, MME width at 12 months was 2.7 ± 1.8 mm in the subtotal resection group, which was significantly larger than in the other groups. …”
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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro by Rebecca Lotz, Christian Osterburg, Apirat Chaikuad, Sabrina Weber, Masato Akutsu, Anne Christin Machel, Ulrike Beyer, Jakob Gebel, Frank Löhr, Stefan Knapp, Matthias Dobbelstein, Xin Lu, Volker Dötsch

“…Moreover, the concomitant loss of the charged amino acids in the alternatively spliced version decreases the affinity of p63 to its cognate DNA element two- to threefold. mRNAs encoding full-length p63, as well as its alternatively spliced version, are present in all tissues that we investigated, albeit in differing ratios. …”
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Segmentation of the iliac crest from CT-data for virtual surgical planning of facial reconstruction surgery using deep learning by Stefan Raith, Tobias Pankert, Jônatas de Souza Nascimento, Srikrishna Jaganathan, Florian Peters, Mathias Wien, Frank Hölzle, Ali Modabber

“…Quantitative evaluation of the correspondence yielded values for geometric agreement in the transplant-relevant area of 92% +/- 7% (Dice coefficient) and average surface deviations of 0.605 +/- 0.41 mm. In all cases, the bones were identified as contiguous objects in the correct spatial orientation. …”
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Intensive critical care and management of asthmatic and smoker patients in COVID-19 infection by Lu Dongming, Yaqoob Obaid, Kumar Manish, Kushwah Ajay Singh, Sharma Rahul Kumar, Kumar Devinder, Mavai Yogendra, Khan Rukaiya

“…Being hospitalized to critical care due to COVID-19, needing mechanical breathing, and suffering from serious health repercussions, are all possible outcomes for someone who has previously smoked. …”
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Comparison of Self-Efficacy and Knowledge of Human Papillomavirus Vaccination among Various Types of Decision Makers in Indonesia: A Cross-Sectional Study by Dora Samaria, Eva Tallutondok, Chandrayani Simanjorang, Imanuel Imanuel

“…The HDM and SDM groups demonstrated the lowest and highest knowledge scores, respectively, across all domains compared to the other groups, encompassing knowledge about HPV infection, cervical cancer, and HPV vaccination. …”
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Factors Associated with the Decline of Kidney Function Differ among eGFR Strata in Subjects with Type 2 Diabetes Mellitus by Shu Meguro, Masuomi Tomita, Yusuke Kabeya, Takeshi Katsuki, Yoichi Oikawa, Akira Shimada, Toshihide Kawai, Hiroshi Itoh, Yoshihito Atsumi

“…AER was significantly correlated with annual eGFR decline in all eGFR strata. Hemoglobin concentration showed a significant correlation only in the advanced eGFR stratum. …”
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Teleconnections detection of land use carbon emissions beyond geographical proximity promotes the construction of cross-city networks by Lei Shen, Yinghong Jiang, Duanqiang Zhai, Peng Wang

“…The Yangtze River Delta urban agglomeration (YRDUA), as one of China's most developed regions, has seen rapid growth in all aspects of the cities due to rapid urbanization. …”
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Growth and survival of Kryptopterus lais treated with thyroxine hormone by , Agusnimar, , Rosyadi

“…The survival of fish were 100% in all treatments.   Keywords: Kryptopterus lais, thyroxine hormone, growth, survival     ABSTRAK   Penelitian ini dilakukan dengan tujuan untuk mengevaluasi pengaruh dosis hormon tiroksin dalam pakan ikan terhadap pertumbuhan dan kelangsungan hidup calon induk ikan selais. …”
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Effect of oral potassium supplementation on urinary potassium excretion and its diagnostic value for primary aldosteronism by Ke Zhang, Xiyun Deng, Zhuoran Li, Chen Yi, Jianqiong Kong, Yunhong Wang

“…Demographic features, 24-hour urine collection before and after potassium supplementation were all collected.Results The patients had a mean age of 49.38 years and 70% were male. …”
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A retrospective record-based study to evaluate the profile of TB patients diagnosed and registered at DOTS center at the tertiary care center and to study the gaps in the implement... by Ruchi Arora Sachdeva, Sahil Singh, MK Sen

“…Conclusion: This study thrusts on intensification of strategies like to improve lab infrastructure, to provide CBNAAT and LPA facilities at all medical colleges and district level, and IEC training to doctors (Interns, Medical officers, specialists), TB health workers and laboratory staff with the latest guidelines, importance of updating Nikshay portal and sensitization of treating physicians and lab personnel to send relevant samples for CBNAAT and LPA testing so as to detect drug-resistant cases on time in order to achieve elimination of disease.…”
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Study of wheat (<i>Triticum aestivum</i> L.) breeding material potential for (<i>Triticum aestivum</i> L.)androgenesis by N. V. Petrash, T. N. Kapko, V. V. Sovetov

“…Ten cultivars of common wheat and the F1 and F2 hybrids of nine combinations were evaluated for the main parameters of in vitro androgenesis such as the number of new formations, albino, green and all regenerated plants. Induction of androgenesis in vitro was carried out in anther culture in growth medium Chu (N6) containing 1 mg/l of growth regulator 2,4-D. …”
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HUMAN DESTRUCTIVENESS IN THE EXISTING PRACTICES OF LATE MODERNISM VIOLENCE: POSITIVE AND NEGATIVE DIMENSIONS by O. V. Marchenko, L. V. Martseniuk

“…The authors are convinced that there is no other way to overcome the negative, malignant destructiveness, except for the incessant, daily gathering of life meanings around them and their development. After all, the loss of such core structures of the existence as the meaning, purpose and value of life has become a truly global problem for the modern world. …”
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Genomic selection for resistance to one pathogenic strain of Vibrio splendidus in blue mussel Mytilus edulis by Munusamy Ajithkumar, Jonathan D’Ambrosio, Marie-Agnès Travers, Romain Morvezen, Lionel Degremont

“…Dead and survivor mussels were all sampled, and among them, 348 dead and 348 surviving mussels were genotyped using a recently published multi-species medium-density 60K SNP array.ResultsFrom potentially 23.5K SNPs for M. edulis present on the array, we identified 3,406 high-quality SNPs, out of which 2,204 SNPs were successfully mapped onto the recently published reference genome. …”
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Exploring the influence of age on the causes of death in advanced nasopharyngeal carcinoma patients undergoing chemoradiotherapy using machine learning methods by Mengni Zhang, Shipeng Zhang, Xudong Ao, Lisha Liu, Shunlin Peng

“…The random forest (RF) model demonstrated the highest concordance index of 0.701 among all models. Time-dependent variable importance plots indicated that age was the most influential factor affecting 3-, 5-, and 10-year survival, followed by metastasis and tumor stage. …”
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A Chisel Generator for Standardized 3-D Die-to-Die Interconnects by Harrison Liew, Farhana Sheikh, Jong-Ru Guo, Zuoguo Wu, Borivoje Nikolic

“…This article presents a framework to generate customized 3-D D2D interconnect physical layers (PHYs) that are simultaneously standard-compliant, physical-aware, and can be automatically integrated into all stacked chiplets. The generator framework leverages the Chisel hardware description language to allow designers to do the following: 1) compile a port list directly into a PHY; 2) automate design and physical design (PD); and 3) perform design space exploration of interconnect features (e.g., bump map pitch, clocking architecture, and others). …”
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