Use of Tramadol or Other Analgesics in Patients Treated in the Emergency Department as a Risk Factor for Opioid Use by Jorge Enrique Machado-Alba, Laura Sofía Serna-Echeverri, Luis Fernando Valladales-Restrepo, Manuel Enrique Machado-Duque, Andrés Gaviria-Mendoza

“…A total of 17.3% (n = 2207) of all patients received an opioid during follow-up. …”
Get full text

Clinical Features of Human Parvovirus B19-Associated Encephalitis Identified in the Dakar Region, Senegal, and Viral Genome Characterization by Al Ousseynou Seye, Fatou Kiné Top, Maimouna Mbanne, Moussa Moise Diagne, Ousmane Faye, Amadou Alpha Sall, Ndongo Dia, Jean-Michel Heraud, Martin Faye

“…Acute encephalitis and encephalopathy are the most common, accounting for 38.8% of all neurological manifestations associated with human B19V. …”
Get full text

Combining Individual‐Based Radio‐Tracking With Whole‐Genome Sequencing Data Reveals Candidate for Genetic Basis of Partial Migration in a Songbird by Matthias H. Weissensteiner, Kira Delmore, Valentina Peona, Juan Sebastian Lugo Ramos, Gregoire Arnaud, Julio Blas, Bruno Faivre, Ivan Pokrovsky, Martin Wikelski, Jesko Partecke, Miriam Liedvogel

“…We estimated genetic differentiation (FST) of single‐nucleotide variants (SNVs) in 2.5 kb windows between all possible population and migratory phenotype combinations, and focused our characterization on birds from the partial migratory population in Germany. …”
Get full text

The Effects of Thyroid Hormone Levels on Patent Ductus Arteriosus Closure in Newborns by Basak KAYA, Hasan AKDUMAN, Dilek DILLI, Semra CETINKAYA, Ahmet OKTEM, Utku Arman ORUN, Mehmet TASAR, Aysegul ZENCIROGLU

“…Results: Thirty-three (51%) of all 65 patients had PDA and responded to medical treatment. …”
Get full text

Can the adherence to quality of care indicators for early rheumatoid arthritis in clinical practice reduce risk of hospitalisation? Retrospective cohort study based on the Record L... by Carlo Alberto Scirè, Antonella Zambon, Greta Carrara, Anna Zanetti, Lisa Argnani

“…Objective To describe the adherence to quality of care indicators in early rheumatoid arthritis (RA) and to evaluate its impact on the risk of hospitalisation in a real-world setting.Design Retrospective cohort study.Setting Patients with early-onset RA identified from healthcare regional administrative databases by means of a validated algorithm between 2006 and 2012 in the Lombardy region (Italy).Participants The study cohort included 14 203 early-onset RA (71% female, mean age 60 years).Outcome measures For each patient, a summary adherence score was calculated starting from the compliance to six quality indicators: (1–2) methotrexate or sulfasalazine or leflunomide with/without glucocorticoids, (3–4) other disease-modifying antirheumatic drugs (DMARDs) with/without glucocorticoids, (5) early interruption of glucocorticoids, (6) early clinical assessment.The relationship between low, intermediate and high categories of the summary score and the 12-month risk of hospitalisation for all causes and for RA was assessed.Results During a follow-up of 1 year, 2609 hospitalisations occurred, of which 704 were for RA (main or secondary diagnosis) and 252 primarily for RA. …”
Get full text

Knowledge, attitude and practice of family caregivers on pressure injury prevention for community-dwelling older adults: a cross-sectional study in an Indonesia City by Sheizi Prista Sari, Irma H. J. Everink, Christa Lohrmann, Yufitriana Amir, Eka Afrima Sari, Ruud J. G. Halfens, Jos M. G. A. Schols

“…Results This study show that more than half of the participants (61.0%) had insufficient knowledge about PI prevention, but nearly all participants (94.4%) had a positive attitude toward PI prevention for their older relatives. …”
Get full text

Effect of Isoniazid Preventive Therapy on the Incidence of Tuberculosis among Seropositive Children Attending HIV/AIDS Care in Two General Hospitals, Northwest Ethiopia, 2021 by Fassikaw Kebede, Birhanu Kebede, Tsehay Kebede, Melaku Agmasu

“…Undertaking in-depth TB screening and frequent follow-up among all these children is critical in order to prevent and control tuberculosis.…”
Get full text

Thromboelastography in Patients with Inflammatory Bowel Disease by Yonghua Shen, Liangliang Shi, Juanjuan Zhang, Hao Zhu, Yuling Yao, Zhenqing Liu, Xiaoping Zou, Xiaoqi Zhang

“…Except for the G level in the CD group, differences in all TEG levels between healthy individuals and IBD patients in remission were not statistically significant. …”
Get full text

Characterization of Cannabis usage in individuals with non-cancer chronic pain in the state of Maine using the Behavioral Risk Factor Surveillance System (BRFSS) by Rachel Bordonaro, Elizabeth N. Bean, Ling Cao

“…Pain group males, pain group females, and control group females were all more likely to report use for medical reasons (p < 0.001). …”
Get full text

Investigating the impact of modified cassava starch with tannic acid and heat moisture treatment on physicochemical and in vitro starch digestibility by Mardiah Rahmadani, Rusli Fidriyanto, Nahrowi, Lilis Khotijah, Anuraga Jayanegara

“…These modifications also significantly (p < 0.01) decreased the digestibility index of starch, rapidly digestible starch, and estimated glycaemic index (GI). Additionally, all treatments exhibited improved water-holding capacity, reduced crystallinity, and altered pasting behavior. …”
Get full text

The Multimessenger Contribution of Ultra-High-Energy Cosmic Rays from Gamma-Ray Bursts by Zhenjiang Li, Fangsheng Min, Yi Jin, Yiqing Guo

“…The most constrained scenario suggests <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>f</mi><mrow><mi>C</mi><mi>R</mi></mrow></msub><mo>≤</mo><mn>15</mn></mrow></semantics></math></inline-formula>, indicating that GRBs are less efficient in producing the all-sky UHECR intensity. The high-energy diffuse neutrinos and gamma rays resulting from interactions between UHECRs from GRBs and extragalactic background photons do not dominate the observations of Fermi-LAT or IceCube.…”
Get full text

Potential benefits and challenges of simulation-based neonatal resuscitation competition: A survey analysis of provincial competition in China by Chenguang Xu, Qianshen Zhang, Fang Lin, Yihua Chen, Yin Xue, Wenjie Yan, Rong Zhou, Yuqian Yang, Po-Yin Cheung

“…The teams were to complete a resuscitation scenario (16 min) and their performance was evaluated. All participants were encouraged to take part in a post-resuscitation questionnaire survey voluntarily immediately after the scenarios finished. …”
Get full text

Bone cell differentiation and mineralization in wild-type and osteogenesis imperfecta zebrafish are compromised by per- and poly-fluoroalkyl substances (PFAS) by Francesca Tonelli, Cecilia Masiero, Carla Aresi, Camilla Torriani, Simona Villani, Guido Premoli, Antonio Rossi, Antonella Forlino

“…Addressing this question represents a need for ensuring global health and wellbeing to all individuals in a world facing the progressive increase of aging and aging related diseases. …”
Get full text

Hairy transcriptional repression targets and cofactor recruitment in Drosophila. by Daniella Bianchi-Frias, Amir Orian, Jeffrey J Delrow, Julio Vazquez, Alicia E Rosales-Nieves, Susan M Parkhurst

“…As expected of direct targets, all of the putative Hairy target genes tested show Hairy-dependent expression and have conserved consensus C-box-containing sequences that are directly bound by Hairy in vitro. …”
Get full text

Cognitive Functions and Cognitive Reserve in Relation to Blood Pressure Components in a Population-Based Cohort Aged 53 to 94 Years by Nunzia Giordano, Valérie Tikhonoff, Paolo Palatini, Anna Bascelli, Giovanni Boschetti, Fabia De Lazzari, Carla Grasselli, Bortolo Martini, Sandro Caffi, Antonio Piccoli, Alberto Mazza, Patrizia Bisiacchi, Edoardo Casiglia

“…In 288 men and women from general population in a cross-sectional survey, all neuropsychological tests were negatively associated with age; memory and executive function were also positively related with education. …”
Get full text

Endoscopic-Assisted Multivessel Off-Pump Coronary Artery Bypass Grafting: Experience of the First 100 Procedures by De Qing Görtzen, Fleur Sampon, Naomi Timmermans, Joost Ter Woorst, Ferdi Akca

“…The study encompassed both elective and urgent surgical revascularization. In all cases, endoscopic-assisted harvesting of the internal mammary artery, radial artery, or saphenous vein was performed, followed by beating-heart anastomoses through a mini-thoracotomy. …”

Effect of the <i>Bifidobacterium animalis</i> Subsp. <i>Lactis</i>, BB-12^® on <i>Cronobacter sakazakii</i> Growth in Infant Formulas with Different Acid-Buffering Capaci... by Anthimia Batrinou, Efstathia Tsakali, Vassilia J. Sinanoglou, Polyvakidi Maria Eleni, Katerina Pyrovolou, Arhontoula Chatzilazarou, Spyros J. Konteles

“…In contrast, at 37 °C during the 24 h co-culture in the lower ABC infant formula, <i>C. sakazakii</i> was <10 CFU/mL. In all co-culture samples, the pH was significantly lower (<i>p</i> < 0.05) in the PIF with the lower ABC. …”
Get full text

Effects of medication procurement reforms and extended prescription duration on medication coverage for hypertension in India’s public health system: a modelling study by Kunihiro Matsushita, Andrew E Moran, Matti Marklund, Prabhdeep Kaur, Lawrence J Appel, T Joseph Mattingly, Swagata Kumar Sahoo

“…The base scenario consisted of procurement of multiple medications across classes, 1-month prescription duration and no use of SPC. We repeated all scenarios with extended prescription duration (3 months vs 1 month).Main outcome measures Medication coverage is defined as the maximum number of patients with adequate medication without exceeding the base scenario budget.Results With 1-month prescriptions, focused procurement alone was estimated to increase medication coverage by 17.8% (95% uncertainty interval: 16.2%; 19.6%) compared with the base scenario. …”
Get full text

Is There a Mild Form of Pediatric Appendicitis? An Eight-Year Single-Center Retrospective Review by Eric Scheier, Khaled Khalilia, Pavel Peslin, Stav Amir, Luba Pasherstnik Bizer

“…Methods: We identified all children diagnosed with appendicitis from June 2016 to June 2024. …”
Get full text

L’aqueduc du Gier : étude des ponts-siphons du Garon à Brignais et Chaponost (Rhône) et de Beaunant à Sainte-Foy-lès-Lyon (Métropole de Lyon) by Kilian Blanc, Laurie Danielou

“…The construction study was based on photogrammetric surveys and a complete examination of all the architectural building blocks. Samples of stone, brick and mortar were taken from the original piles and the backfill of both bridges in order to identify the different materials employed. …”
Get full text