Preliminary Clinical Study on Therapy of Lidocaine Local Block Combined with Acupuncture-rehabilitation in Treatment of Post-stroke Upper Limb Spasticity by Ji LI, Li ZHANG, Ying GUAN, Lu WANG, Guile XIN, Yanli XING, Qiang TANG

“…Objective:To compare the clinical efficacy of Lidocaine local block combined with acupuncture-rehabilitation method and conventional acupuncture-rehabilitation method in the treatment of upper limb spasticity among post-stroke patients.Methods:Sixty cases of post-stroke upper limb spasticity patients who met the inclusion criteria in our hospital from June 2017 to June 2020, were selected. All the patients were randomly divided into observation group and control group, with 30 cases in each group. …”
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Analysis of factors affecting pregnancy outcomes in patients with adenomyosis after high intensity focused ultrasound ablation: a retrospective study by Rong Ma, Diego Armando Burgos Briones, Min Zou, Yu Xiong, Jin Bai, Lian Zhang

“…Objectives To investigate all pregnancies and analyze the factors influencing pregnancy outcomes in patients with adenomyosis after high intensity focused ultrasound (HIFU).Materials and methods A total of 231 patients with adenomyosis who completed HIFU and wished to conceive were enrolled. …”
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Effectiveness of Outpatient Chronic Pain Management for Middle-Aged Patients by Internet Hospitals: Retrospective Cohort Study by Ling Sang, Bixin Zheng, Xianzheng Zeng, Huizhen Liu, Qing Jiang, Maotong Liu, Chenyu Zhu, Maoying Wang, Zengwei Yi, Keyu Song, Li Song

“…During the first and last patient visits, information on outcome variables such as the Brief Pain Inventory (BPI), medical satisfaction, medical costs, and adverse drug events was obtained through a telephone follow-up. All patients with chronic pain who had 3 or more visits (internet or offline) between September 2021, and February 2023, were included. …”
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Triiodothyronine (T3) increases the expression of the amphiregulin (AREG) oncogene by activating extranuclear pathways in MCF-7 breast cancer cells by Maria Teresa De Sibio, Fernanda Cristina Fontes Moretto, Regiane Marques Castro Olimpio, Miriane de Oliveira, Lucas Solla Mathias, Vinícius Vigliazzi Peghinelli, Helena Paim Tilli, Bianca Mariani Gonçalves, Dariane Beatriz Marino Cardoso, Larissa Silva Dall Aqua, Igor de Carvalho Depra, Mariana Menezes Lourenço, Aline Carbonera Luvizon, Paula de Oliveira Montandon Hokama, Maria Tereza Nunes, Marna Eliana Sakalem, Célia Regina Nogueira

“…Results: We observed that T3 increased AREG expression, an effect that was suppressed by all inhibitors. This finding indicates that the activation of the αvβ3 integrin signaling pathway, via PI3K, MAPK/ERK, is necessary for the T3-mediated effects on AREG expression and highlights the involvement of nongenomic mechanisms. …”
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How do families access holiday activities and food programmes and other support? Learnings from the Borough of Southwark holiday activities and food club’s evaluation by Lorraine McSweeney, Anita Sewornu, Louis Goffe, Bronia Arnott, Ashley Adamson

“…There was also a lack of awareness of the types of other support/signposting available from clubs.DiscussionThe evaluation highlighted the low-level of family awareness of all available HAF activities across the borough. …”
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Longitudinal association between hemoglobin and lung function with insights into the incidence of airflow obstruction: an observational study by Jihoon Kim, Yun Tae Kim, Ah Young Leem, Ji Ye Jung, Young Sam Kim, Youngmok Park

“…Results Over an 8-year biennial follow-up of 4,468 individuals (median age, 53.9 years; men, 49.0%), we observed that in men, Hb levels were positively associated with lung function (estimated values of FVC: 16.7 mL, FEV1: 15.5 mL, FEV1/FVC: 0.18%; all P < 0.001) and a decreased incidence of AO (OR = 0.83, P < 0.001). …”
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Cigarette Smoking Is Associated with Prolongation of the QTc Interval Duration in Patients with Type 2 Diabetes Mellitus by Petros Thomakos, Stavros Liatis, Stavroula Kalopita, Ioannis Vlahodimitris, Chryssoula Stathi, Nicholas Katsilambros, Nicholas Tentolouris, Konstantinos Makrilakis

“…There was no difference regarding all measures of ANS activity between the two groups. …”
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Clinicopathological study and molecular subtyping of muscle-invasive bladder cancer (MIBC) using dual immunohistochemical (IHC) markers by R. Vaithegi, Kanthilatha Pai, Anuradha Calicut Kini Rao, Vidya Monappa, Swathi Prabhu, Nischitha Suvarna

“…The double-negative subtype was found exclusively in males and exhibited a non-papillary morphology. Notably, all diagnosed neuroendocrine carcinomas were classified as double-negative type. …”
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A Prospective Study of Tuberculosis Drug Susceptibility in Sabah, Malaysia, and an Algorithm for Management of Isoniazid Resistance by Muhammad Redzwan S. Rashid Ali, Uma Parameswaran, Timothy William, Elspeth Bird, Christopher S. Wilkes, Wai Khew Lee, Tsin Wen Yeo, Nicholas M. Anstey, Anna P. Ralph

“…Seven people (4.5%) had isoniazid resistance (INH-R); all were switched to an appropriate second-line regimen for varying durations (4.5–9 months). …”
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Neurohypophysial Receptor Gene Expression by Thymic T Cell Subsets and Thymic T Cell Lymphoma Cell Lines by I. Hansenne, G. Rasier, Ch. Charlet-renard, M.-P. Defresne, R. Greimers, C. Breton, J.-J. Legros, V. Geenen, H. Martens

“…The objective of this study was to identify the nature of neurohypophysial receptor in thymic T cell subsets purified by immunomagnetic selection, as well as in murine thymic lymphoma cell lines RL12-NP and BW5147. OTR is transcribed in all thymic T cell subsets and T cell lines, while V3R transcription is restricted to CD4+ CD8+ and CD8+ thymic cells. …”
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TAX COMPLIANCE RISK AS AN ELEMENT OF THE TAX RISK MANAGEMENT CONCEPT IN AN ENTERPRISE by Olha Mashchenko, Anastasiia Khodus

“…The main compliance risks cover the processes from state registration of business entities to the final result - payment of taxes and fees to the budgets of all levels, which covers the process of administering taxes of business entities and is an integral part of business activities. …”
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Use of linear features by red-legged partridges in an intensive agricultural landscape: implications for landscape management in farmland by Perrot, Charlotte, Seranne, Léo, Berceaux, Antoine, Noël, Mathias, Arroyo, Beatriz, Bacon, Léo

“…Further, breeding birds select linear elements with herbaceous cover while non-breeders select linear elements with woody cover, underlining the different needs of birds according to their breeding status. All birds selected areas near tracks, but non-breeders seemed to avoid roads. …”
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Patients’ preferences for health insurance coverage of new technologies for treating chronic diseases in China: a discrete choice experiment by Jinsong Geng, Xiaowei Chen, Haini Bao, Danmin Qian, Yuting Shao, Hao Yu

“…The out-of-pocket cost was a significant, negative attribute for the entire study sample (β = −0.258, p&lt;0.01) and for the patients with Urban-Rural Residents Basic Medical Insurance (URRBMI) (β = −0.511, p&lt;0.01), but not for all the patients with Urban Employees Basic Medical Insurance (UEBMI) (β = −0.071, p&gt;0.05). …”
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Specific Blood Cells Derived from Pluripotent Stem Cells: An Emerging Field with Great Potential in Clinical Cell Therapy by Qian Luo, Honghu Li, Wei Shan, Cong Wei, Yan Long, Shuyang Cai, Xiangjun Zeng, Xue Li, Yulin Xu, Xiaoxiao Xu, Yi Luo, Pengxu Qian, He Huang

“…Widely known for self-renewal and multilineage differentiation, stem cells can be differentiated into all specialized tissues and cells in the body. In the past few years, a number of researchers have focused on deriving hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) as alternative sources for clinic. …”
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Qualitative and Quantitative Detection of Virulence-Associated Genes in Escherichia Coli Isolates from Women with Urinary Tract Infections by Zainab Hussein Mahdi, Lina S. Alsaadi, Zainab Amer Hatem, Saade Abdalkareem Jasim

“…The traditional PCR results showed the presence of both 16S rRNA and uidA gene in all 25 isolates of E. coli. In contrast, the results showed that  23 (92%) and 18 (72%) isolates possessed fimA and kpsMTII genes, respectively. …”
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Nurse compliance with a protocol for safe injectable medication administration: comparison of two multicentre observational studies by Martine de Bruijne, Peter Spreeuwenberg, Cordula Wagner, Bernadette Schutijser, Joanna Ewa Klopotowska, Irene Jongerden

“…Objectives Medication administration errors with injectable medication have a high risk of causing patient harm. To reduce this risk, all Dutch hospitals implemented a protocol for safe injectable medication administration. …”
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The impact of human papillomavirus (HPV) status on functional outcomes and quality of life (QOL) after surgical treatment of oropharyngeal carcinoma with free-flap reconstruction by Hani Z. Marzouki, Vincent L. Biron, Peter T. Dziegielewski, Andrew Ma, Jason Vaz, Gabriela Constantinescu, Jeffrey Harris, Daniel O’Connell, Hadi Seikaly

“…Methods A retrospective review of a prospectively collected database of all patients with OPSCC diagnosed and treated from 1998 to 2009. …”
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Nephrotic and Non-Nephrotic Focal Segmental Glomerulosclerosis: Clinical Characteristics, Etiology, and Columbia Classification by Gabriel Figueiredo, Luis Yu, Lectícia Barbosa Jorge, Viktoria Woronik, Cristiane Bitencourt Dias

“…Progression to renal replacement therapy occurred in 31.3% of the patients in the nephrotic group and in 26.8% of those in the non-nephrotic group, with no statistical difference between them. All of the non-nephrotic group patients who progressed to renal replacement therapy were analyzed by electron microscopy, the diagnosis of FSGS was confirmed, and there was the finding of high chronicity in these patients. …”
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Global, regional, and national esophageal cancer deaths and DALYs attributable to diet low in vegetables and fruits, 1990–2019: analysis for the global burden of disease study by Bing Cui, Aqin Chen, Chengcheng Xu

“…Frontier analysis was used to evaluate the relationship between dietary risk-related disease burden and sociodemographic progress.ResultsIn 2019, inadequate vegetable and fruit intake contributed to 65,919 global EC deaths, accounting for 0.12% of all deaths, with an age-standardized death rate of 0.81 per 100,000 population. …”
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A new class of natural anthelmintics targeting lipid metabolism by Hala Zahreddine Fahs, Fathima S. Refai, Suma Gopinadhan, Yasmine Moussa, Hin Hark Gan, Yamanappa Hunashal, Gennaro Battaglia, Patricia G. Cipriani, Claire Ciancia, Nabil Rahiman, Stephan Kremb, Xin Xie, Yanthe E. Pearson, Glenn L. Butterfoss, Rick M. Maizels, Gennaro Esposito, Antony P. Page, Kristin C. Gunsalus, Fabio Piano

“…In C. elegans, AFA exposure affects all developmental stages, causing paralysis, impaired mitochondrial respiration, increased reactive oxygen species production and mitochondrial damage. …”
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