Present-day mass loss rates are a precursor for West Antarctic Ice Sheet collapse by T. van den Akker, W. H. Lipscomb, G. R. Leguy, J. Bernales, C. J. Berends, W. J. van de Berg, R. S. W. van de Wal, R. S. W. van de Wal

“…The dynamical response shows slow grounding-line retreat over several centuries, followed by a phase of rapid mass loss over about 200 years with a consistent rate of <span class="inline-formula">∼3</span> mm GMSL yr<span class="inline-formula">⁻¹</span> (global mean sea level). We find that, for all ensemble members, the Thwaites Glacier and Pine Island Glacier collapse. …”
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Genetic Diversity and Population Differentiation of Guignardia mangiferae from “Tahiti” Acid Lime by Ester Wickert, Eliana Gertrudes de Macedo Lemos, Luciano Takeshi Kishi, Andressa de Souza, Antonio de Goes

“…As gene flow was detected among the studied populations and they share haplotypes, it is possible that all populations, from citrus plants and also from the other known hosts of this fungus, belong to one great panmictic population.…”
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The Promising Key Factors Mediating Secondary Neuronal Damage in the Perihematomal Region of Intracerebellar Hemorrhage of Mice by Saandeep Bhatia, Ramissh Paramasivam, Mohd Khairul Izamil Bin Zolkefley, Regunath Kandasamy, Sangu Muthuraju, Jafri Malin Abdullah

“…The mice were grouped into four groups: (1) control group (n = 12), (2) day-1 group (n = 12), (3) day-3 group (n = 12), and (4) day-7 group (n = 12). All mice underwent behavior assessment following induction of ICbH and were subsequently sacrificed on days 1, 3, and 7. …”
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Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis by Kentarou Yoshizawa, Nao Yasuda, Michinari Fukuda, Yumi Yukimoto, Mieko Ogino, Wakana Hata, Ikuyo Ishizaka, Mari Higashikawa

“…Although sample size was small, these patients had a low STA score but normal FAB and RCPM score. All patients with bulbar onset ALS had syntactic comprehension disorder. …”
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Automatic Classification of Difficulty of Texts From Eye Gaze and Physiological Measures of L2 English Speakers by Javier Melo, Leigh Fernandez, Shoya Ishimaru

“…Combining sensor data from all modalities improved predictions in both LoDo and LoPo cross-validation, compared to each modality in isolation. …”
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Rare Manifestation of a Rare Disease, Acute Liver Failure in Adult Onset Still’s Disease: Dramatic Response to Methylprednisolone Pulse Therapy—A Case Report and Review by Nalini Valluru, Venkata S. Tammana, Michael Windham, Eyasu Mekonen, Rehana Begum, Andrew Sanderson

“…Extensive workup excluded all potential causes of liver failure. She was diagnosed with AOSD associated acute liver failure (ALF). …”
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Differential impact of lifestyle factors on 2-hour glucose values in individuals with type 2 diabetes: potential for more personalized interventions by Hanno Pijl, Tim Snel, Tanja Krone, Regina J M Kamstra, Hannah M Eggink, Albert A de Graaf, Iris M de Hoogh

“…Although carbohydrate intake led to increased glucose concentrations in 2 hours in all individuals, the magnitude of this effect varied between individuals. …”
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Downregulation of the Proinflammatory State of Circulating Mononuclear Cells by Short-Term Treatment with Pioglitazone in Patients with Type 2 Diabetes Mellitus and Coronary Artery... by Andreas Pfützner, Alexander Weise, Elisabeth Pfützner-Riehn, Georg Lübben, Michael Morcos, Efstrathios Karagiannis, Matthias Weber, Thomas Forst

“…., P105 pioglitazone: −19%/placebo: +6%, RelA: −20%/+2%, MMP−9: −36%/+9%, TNFα: −10%/+14%, P<0.05 between groups in all cases). Conclusions. Pioglitazone very rapidly down-regulated the activated state of peripheral monocytes/macrophages as assessed by mRNA expression of NFκB and NFκB-modulated cytokines and decreased plasma levels of cardiovascular risk marker proteins independent of glycemic control.…”
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Dynamics of blackleg epizootic process in the Republic of Kazakhstan by A. Abutalip, B. D. Aitzhanov, A. K. Mussayeva, V. Yu. Sushchikh, N. N. Yegorova, Ye. K. Ospanov, M. A. Berdikulov, K. A. Kalkabayev, N. Matikhan

“…In 2012–2021, 2,030 outbreaks of acute infectious animal diseases were registered in the Republic of Kazakhstan. Among all the diseases blackleg accounted for 20.7% (421 outbreaks), which suggests that the nosological unit is of high epizootological significance among other infectious animal diseases in the country. …”
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‘Customary’ use of stick tools by chimpanzees in Bulindi, Uganda: update and analysis of digging techniques from behavioural observations by Matthew R. McLennan, Jacqueline Rohen, Zoe Satsias, Tom Sabiiti, John-Mary Baruzaliire, Marie Cibot

“…., occurring in most or all adult, subadult and juvenile individuals. The chimpanzees use stick tools in various foraging contexts, for example as probes to investigate branches or logs containing insect prey or products (e.g., Apis mellifera and Xylocopa sp. bee nests, and unidentified grubs or larvae), as well as for excavating Meliponini ground nests. …”
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Usefulness of an Image Fusion Model Using Three-Dimensional CT and MRI with Indocyanine Green Fluorescence Endoscopy as a Multimodal Assistant System in Endoscopic Transsphenoidal... by Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Naoya Nishida, Yawara Nakamura, Yoshihiro Ohtsuka, Shirabe Matsumoto, Shiro Ohue

“…Thirty-five consecutive patients undergoing ETSS in our hospital between April 2014 and March 2015 were enrolled in the study. In all patients, fusion models of 3D-CT and MRI were created by reconstructing preoperative images. …”
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Finite element analysis of stress in mandibular molars repaired after fractured instrument removal by Salih Düzgün, Emir Esim, Tuğrul Aslan, Ayşe Tuğba Eminsoy Avcı

“…Furthermore, calcium silicate-based materials alone or in combination with Gutta-percha showed similar stress levels, suggesting their potential use for root canal filling. All models demonstrated structural integrity within safe limits.…”
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Degradation of 4-nonylphenol in bromide-containing water by UVC/O3/TiO2-combination processes: Impacts on trihalomethanes and haloacetic acids formation by Muammar Qadafi, Raden Tina Rosmalina, Hanny Meirinawati, Widyarani, Diana Rahayuning Wulan

“…The UVC-combination process was conducted with standalone UVC, UVC/O3, and photocatalytic ozonation using UVC/O3/TiO2. All the process was conducted for 5, 10, 15, 20, 25, and 30min. …”
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Progression of Luminal Breast Tumors Is Promoted by Ménage à Trois between the Inflammatory Cytokine TNFα and the Hormonal and Growth-Supporting Arms of the Tumor Microenvironment... by Polina Weitzenfeld, Nurit Meron, Tal Leibovich-Rivkin, Tsipi Meshel, Adit Ben-Baruch

“…Importantly, the tumor cells used in this study are known to be nonmetastatic under all conditions; nevertheless, they have acquired high metastasizing abilities in vivo in mice, following a brief stimulation by TNFα + Estrogen + EGF. …”
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Physicochemical Characterization, Storage Stability Behavior, and Intestinal Bioaccessibility of Clove Extract Encapsulated Using Varying Combinations of Gum Arabic and Maltodextri... by Farhad Ahmadi, Hafiz A. R. Suleria, Frank R. Dunshea

“…Encapsulation was effective in protecting bioactive components of clove extract during storage at room (up to 40 days) or high temperature (60 °C for 7 days) and minimized the loss of antioxidant activity during storage, as compared to the clove extract in a non-encapsulated form. All encapsulation formulations were characterized by a negative zeta potential (from −22.1 to −29.7 mV) and a polydispersity index ranging from 0.47 to 0.68, classifying the formulations as having a mid-range polydisperse particle size distribution. …”
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Exploring the epidemiology of disseminated intravascular coagulation: protocol for the DANish Disseminated Intravascular Coagulation (DANDIC) Cohort Study by Henrik Toft Sørensen, Kasper Adelborg, Jecko Thachil, Anne-Mette Hvas, Simon Flæng, Søren Nygaard, Asger Granfeldt

“…The project will use state-of-the-art epidemiological and biostatistical methods.Ethics and dissemination The project has been approved by the Danish Patient Safety Authority (31-1521-452), the Central Denmark Region (1-45-70-83-21), the Danish Data Protection Agency (1-16-02-258-21) and all the hospital chairs. Register-based studies require no ethical approval in Denmark. …”
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Programmed cell death 1 inhibitor alone or combined with chemotherapy for patients with locally advanced or metastatic urothelial carcinoma: a single-center experience by Xing Huang, Chupeng Sun, Peng Zhang, Lei Wang

“…The median OS was 16.0 months (95% CI: 11.9–20.1), and median PFS was 12.0 months (95% CI: 8.6–15.4) for all patients. PD-1 inhibitor combined with chemotherapy was associated with better PFS than PD-1 inhibitor monotherapy (HR: 0.19, p = 0.018). …”
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Horses are worthy of care: Horse sector participants’ attitudes towards animal sentience, welfare, and well-being by Julie M Fiedler, Margaret L Ayre, Sarah Rosanowski, Josh D Slater

“…A cross-sectional survey captured the attitudes of experienced horse sector participants regarding sentience, welfare and well-being. Almost all respondents (99.9%; n = 676/677), believed horses were sentient. …”
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A modified non-contrast MRI in the preoperative examination of periacetabular osteotomy at 3.0T by Chuanhui Xu, Xin Pan, Baochen Song, Guangwei Zhang, Daguang Zhang

“…Each patient underwent both d-MRA and modified 3.0T non-contrast MRI examination of the hip joint. All patients underwent hip-preserving PAO surgery subsequently. …”
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Impact of Early versus Late Referral to Nephrologists on Outcomes of Chronic Kidney Disease Patients in Northern India by Manoj Dhanorkar, Narayan Prasad, Ravi Kushwaha, Manas Behera, Dharmendra Bhaduaria, Monika Yaccha, Manas Patel, Anupama Kaul

“…In this observational cohort study, all CKD patients who visited the nephrology OPD of the institute between Nov 1, 2018, and Dec 31, 2020, were classified as early referral (ER) if their first encounter with a nephrologist occurred more than one year before initiation of dialysis and education about dialysis (from a nurse or nephrologist). …”
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