The Effect of Local Melatonin Application on Bone Fracture Healing in Rat Tibias by Murat Tanrisever, Bahar Tekin, Umit Koray Can, Ozmen Istek, Erhan Cahit Ozcan, Ibrahim H. Ozercan, Turker Gelic, Serkan Dundar

“…After a 12-week healing period, all subjects were sacrificed, and tibial bones were collected for histomorphometric analysis. …”
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Changes in Polyphenols Contents and Antioxidant Capacities of Organically and Conventionally Cultivated Tomato (Solanum lycopersicum L.) Fruits during Ripening by Dea Anton, Ingrid Bender, Tanel Kaart, Mati Roasto, Marina Heinonen, Anne Luik, Tõnu Püssa

“…Although contents of some polyphenols decreased during ripening, total phenolics and free radical scavenging activity increased in all studied cultivars and in case of both cultivation modes. …”
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Implementation of rural provider-to-provider telehealth in country Western Australia: a retrospective observational analysis via the RE-AIM framework by Kaylie Toll, Suzanne Robinson, Stephen Andrew, Aled Williams, Justin Yeung, Richard Varhol, Joanna C. Moullin

“…Methods A retrospective observational analysis was conducted of all patient contacts managed by clinical telehealth streams of the Command Centre, between 31 August 2012 and 31 December 2023. …”
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Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) by Jean Joury, Nawal Al Kaabi, Sara Al Dallal, Bassam Mahboub, Mostafa Zayed, Mohamed Abdelaziz, Jennifer Onwumeh-Okwundu, Mark A. Fletcher, Subramanyam Kumaresan, Badarinath C. Ramachandrachar, Mohamed Farghaly

“…The average length of hospitalization was about 4 days across all cohorts. The total hospitalization cost was highest in patients <2 years, amounting to US $9 798 174 (median, US $2241.30). …”
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Forensic tactics: a review of the formation history and current trends by O. P. Shaituro

“…It is noted that it is expedient to study the tactics of all participants in criminal proceedings such as judges, courts, investigators, detectives, prosecutors, employees of operational units, etc. …”
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TNRC6C Functions as a Tumor Suppressor and Is Frequently Downregulated in Papillary Thyroid Cancer by Zhenqin Cai, Tianyu Zhai, Dilidaer Muhanhali, Yan Ling

“…By analyzing RNA-sequencing data and TCGA data, 12 genes (SCD, CRLF1, APCDD1L, CTHRC1, PTPRU, ALDH1A3, VCAN, TNC, ECE1, COL1A1, CAMK2N2, and MMP14) were considered as potential target genes of TNRC6C, and most of them were associated with clinicopathological features of PTC in TCGA. All of them except CAMK2N2 were significantly downregulated after overexpressing TNRC6C. …”
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Extracellular Vesicles: A New Prospective in Crosstalk between Microenvironment and Stem Cells in Hematological Malignancies by Ilaria Laurenzana, Daniela Lamorte, Stefania Trino, Luciana De Luca, Concetta Ambrosino, Pietro Zoppoli, Vitalba Ruggieri, Luigi Del Vecchio, Pellegrino Musto, Antonella Caivano, Geppino Falco

“…Cancer stem cells (CSCs), neoplastic cells, hematopoietic stem cells (HSCs), and mesenchymal stromal/stem cells (MSCs) are all components of this microenvironment. CSCs are the HM initiators and are associated with neoplastic growth and drug resistance, while HSCs are able to reconstitute the entire hematopoietic system; finally, MSCs actively support hematopoiesis. …”
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Bidimensionally partitioned online sequential broad learning system for large-scale data stream modeling by Wei Guo, Jianjiang Yu, Caigen Zhou, Xiaofeng Yuan, Zhanxiu Wang

“…Firstly, IBLS needs to retain all historical data and perform associated calculations in the incremental learning process, which causes its computational overhead and storage burden to increase over time and as such puts the efficacy of the algorithm at risk for massive or unlimited data streams. …”
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Performance of high-strength and heat-resistant cast aluminum alloy and its complex shell castings for aircraft engines by QIE Juhong, XIE Feng, FENG Chao, WANG Pinghai, YU Tengfei, YANG Chaoyang, XI Honglei, XIAO Wenlong, MA Chaoli

“…The surface quality， internal quality， airtightness， and pressure resistant performance of the casting case all meet the design requirement of the product.…”
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Development and validation of a prediction model for chronic post-surgical pain risk: a single-center prospective study of video-assisted thoracoscopic lung cancer surgery by Xiong-Fei Zhang, Chang-Guo Peng, Hua-Jing Guo, Zhi-Ming Zhang

“…And the DCA curve showed that using our model to guide decisions resulted in a higher net benefit compared to a strategy of not screening or treating all patients. Conclusion An effective risk prediction model for CPSP was successfully developed and validated in this study. …”
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Squamate reptiles may have compensated for the lack of γδTCR with a duplication of the TRB locus by Jordan M. Sampson, Kimberly A. Morrissey, Kieran J. Mikolajova, Kourtney M. Zimmerly, Neil J. Gemmell, Michael G. Gardner, Terry Bertozzi, Terry Bertozzi, Robert D. Miller

“…TRE is absent from the genomes of the tuatara and all Archosaurs examined and appears squamate specific.…”
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Treatment of Hepatitis C Post-Liver Transplantation Could Mitigate Discard Rates of Hepatitis C-Positive Deceased Donor Livers and Expand the Donor Pool by Jennifer Keller, Gary Marklin, Obi Okoye, Roshani Desai, Tej Sura, Ajay Jain, Chintalapati Varma, Mustafa Nazzal

“…Comparison was made before the widespread use of DAAs 2008–2013 (pre-DAA) against their common practice use 2014–2017 (post-DAA). All deceased liver donors with HCV antibody or nucleic acid positive results were evaluated. …”
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Routine antibiotics for infants less than 6 months of age with growth failure/faltering: a systematic review by Jai K Das, Zulfiqar Ahmed Bhutta, Abigail Smith, Aamer Imdad, Olivia Tsistinas, Emily Tanner-Smith, Melissa François, Fanny F Chen, Momal Sana

“…The comparison group was infants who received antibiotics according to the aforementioned guidelines.Primary and secondary outcomes The primary outcome was all-cause mortality, and secondary outcomes: clinical deterioration, antimicrobial resistance, recovery from comorbidity, adverse events, markers of intestinal inflammation, markers of systemic inflammation, hospital-acquired infections and non-response. …”
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Clinical Investigation of Benign Asbestos Pleural Effusion by Nobukazu Fujimoto, Kenichi Gemba, Keisuke Aoe, Katsuya Kato, Takako Yokoyama, Ikuji Usami, Kazuo Onishi, Keiichi Mizuhashi, Toshikazu Yusa, Takumi Kishimoto

“…There were 110 BAPE patients between 1991 and 2012. All were males and the median age at diagnosis was 74 years. …”
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PathoGD: an integrative genomics approach to primer and guide RNA design for CRISPR-based diagnostics by Soo Jen Low, Matthew O’Neill, William J. Kerry, Natasha Wild, Marcelina Krysiak, Yi Nong, Francesca Azzato, Eileen Hor, Lewis Williams, George Taiaroa, Eike Steinig, Shivani Pasricha, Deborah A. Williamson

“…We demonstrated high specificity of primers and gRNAs designed, with minimal off-target signal observed for all combinations. We anticipate PathoGD will be an important resource for assay design for current and emerging pathogens. …”
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Derivation of Sa-MoDEI score from DEI. Tak for prognostication in Buerger's Disease - Preliminary data of a prospective observational cohort by Gregory Pathrose, Albert A Kota, Prabhu Premkumar, Prasanna Samuel, Shivraj Padiyar, Deepak Selvaraj, Prasanta Padhan, Debashish Danda

“…Results: There were 84 patients with Buerger's disease. All were male with a significant history of tobacco use (smoking cigarettes or “beedis” [leaf cigarettes used in south Asian nations especially in countryside], chewing tobacco, and inhaling snuff). …”
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Simulation and experiment of leakage and diffusion of natural gas pipelines with different burial depths under different pressures by Chengbin Zhang, Yaoqiang Hu, Zhao Dong, Zhaofeng Yang, Dongrui Yi

“…The errors of the finite element numerical solution and the experimental values of the leakage pressure drop curve of the buried natural gas pipeline under four working conditions are 5.9%, 5.5%, 5.2%, and 5.0%, which are all within the allowable range. The accuracy of the finite element calculation results and the reliability of the test are verified.…”
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Efficacy and safety of perioperative analgesia in PENG block for children undergoing hip surgery with developmental dysplasia: study protocol for a randomized, double-blinded, non-... by Mingzhe Xu, Yi He, Zhi Li, Bin Du

“…Secondary outcomes include intraoperative opioid consumption, analgesic dosage within 24 h of surgery, time to start rescue analgesia, number of PCA pump activations, time to remove SLIPA (streamlined liner of the pharynx airway), duration of regional block procedures, incidence of adverse events, plasma ropivacaine concentrations, and hospital stays and costs. All data will be collected by blinded investigators. …”
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Direct-Acting Antivirals in Hepatitis C Treatment for Renal Impairment: Liver Safety Concerns and Effectiveness in Peritoneal Dialysis by Hsuan-Yu Hung, Wei-Liang Hung, Ye Gu, Chung-Yu Chen

“…A case–time–control analysis suggested liver instability despite treatment, with comorbid liver tumors (aOR 18.89; 95% CI 5.4–66.12) and hypertension (aOR 4.25; 95% CI 1.49–12.15) linked to higher DILI risk. All peritoneal dialysis patients (<i>n</i> = 10) achieved a 100% SVR12 rate. …”
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Fiber optic control system for geotechnical parameters of mine by A. D. Mekhtiyev, A. I. Soldatov, Ye. G. Neshina, A. D. Alkina

“…The reasons for the need to create a safe system are given, the main requirement of which is the condition of compliance with all safety requirements during mining operations. …”
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