Meta-Analysis of Randomized Trials: Efficacy and Safety of Colchicine for Secondary Prevention of Cardiovascular Disease by Elie Akl, Nazanin Sahami, Christopher Labos, Jacques Genest, Ali Zgheib, Nicolo Piazza, Sanjit Jolly

“…Risks of MI (OR 0.75, 95% CI 0.62 to 0.91, P=0.003; I2=33%), stroke (OR 0.47, 95% CI 0.30 to 0.74, P=0.001; I2=0%), and unplanned coronary revascularization (OR 0.67, 95% CI 0.55 to 0.82, P=0.0001; I2=58%) were all reduced in the colchicine group. Rates of CV and all-cause mortality did not differ between the two groups, but there was an increase in noncardiac deaths with colchicine (OR 1.54, 95% CI 1.10 to 2.15, P=0.01; I2=51%). …”
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Detection of Francisellaceae and the differentiation of main European F. tularensis ssp. holarctica strains (Clades) by new designed qPCR assays by Kristin Köppen, Kerstin Rydzewski, Julia Zajac, Marwah Al-Senwi, Sema Evcimen, Darius Schulze, Daniela Jacob, Klaus Heuner

“…The methods currently available were not made for a fast and easy detection of all these strains and genera of Francisellaceae. …”
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Do... by Yang M, Zhou L, Long G, Liu X, Ouyang W, Xie C, He X

“…Intranasal insulin elevated the levels of tOC, ucOC, and BDNF in the CSF on D0 (all P< 0.001) and tOC levels in the plasma on D0, D1 and D3 (all P< 0.001). …”
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Effect of immunomodulation on cardiac remodelling and outcomes in heart failure: a quantitative synthesis of the literature by Navkaranbir S. Bajaj, Kartik Gupta, Nitin Gharpure, Mike Pate, Lakshay Chopra, Rajat Kalra, Sumanth D. Prabhu

“…Secondary outcomes were changes in LVEDD and all‐cause mortality. TSA was used to quantify the statistical reliability of data in the cumulative meta‐analyses. …”
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Effect of Preoperative Nutritional Risk Screening on Postoperative Recovery in Patients with Laparoscopic-Assisted Radical Resection for Colorectal Cancer by Xiaolong Wang, Jianlin Wu, Sen Lei, Feng Tian, Ce Cao, Guangfeng Shi

“…There were no significant differences between the two groups regarding abdominal drainage volume, exhaust (flatus) time, hospitalization cost, morbidity, or 60 d readmission rate (all P>0.05). However, patients with nutritional risk had higher postoperative blood transfusion volumes, albumin infusions, weight difference before and after surgery, and postoperative hospital stays than the nonnutritional risk group (all P<0.05). …”
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Effectiveness of a personal health coaching intervention (diabetescoach) in patients with type 2 diabetes: protocol for an open-label, pragmatic randomised controlled trial by Oliver Faude, Fiona Streckmann, Lukas Zahner, Markus Gerber, Vivien Hohberg, Jan-Niklas Kreppke, Jan Kohl, Eleonora Seelig, Daniel König

“…This superiority study will be conducted in Switzerland. All enrolled patients (n=90) will receive the standard medical treatment for T2D. …”
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Treatment and prescribing trends of antihypertensive drugs in 2.7 million UK primary care patients over 31 years: a population-based cohort study by Tibor Schuster, Laurent Azoulay, Julie Rouette, Emily G. McDonald, James M. Brophy

“…Most patients with hypertension initiated guideline-recommended first-line agents. Not all patients, particularly females, were prescribed recommended agents however, potentially leading to suboptimal cardiovascular outcomes. …”
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Breeding value of prolific maize varieties with nicking of parental lines by E. B. Khatefov, R. A. Kudaev, R. S. Kushkhova

“…The analysis of the lines and their topcrosses helped to systemize all lines into 4 groups according to their ability to transfer the gene of the multiple-ear trait into F1. …”
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Design and Dynamic Analysis of Ideological and Political Education Platform Based on Network Multimedia Technology by Xiaowen Chen

“…As a group of users in the “digital age”, college students’ thinking, behavior, and concept are all influenced by the multimedia network. The fast growth of multimedia network not only brings thought-political opportunities to students, but also brings problems. …”
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Inguinal Lymph Node Dissection for Advanced Stages of Plantar Melanoma in a Low-Income Country by Ollo Roland Somé, Malick Diallo, Damien Konkobo, Nassirou Yabré, Valentin Konségré, Issouf Konaté, Sidy Ka

“…Four-year prospective study. Patients. We included all documented cases of advanced stage plantar melanoma with clinically detectable inguinal lymph node metastasis. …”
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Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review. by Laith Hussain-Alkhateeb, Tatiana Rivera Ramírez, Axel Kroeger, Ernesto Gozzer, Silvia Runge-Ranzinger

“…A scoping review has been undertaken for all 5 diseases to summarize existing evidence of EWS tools in terms of their structural and statistical designs, feasibility of integration and implementation into national surveillance programs, and the users' perspective of their applications.…”
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Neurophysiological Effects of Chronic Indoor Environmental Toxic Mold Exposure on Children by Ebere C. Anyanwu, Andrew W. Campbell, Aristo Vojdani

“…The EEG examination was abnormal in seven out of ten of the patients compared to the controls with only one in ten with episodes of bihemispheric sharp activity. In all the patients, there was frontotemporal theta wave ativity that seemed to indicate diffuse changes characteristic of metabolic encephalopathies. …”
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Patterns of Comorbidity and Multimorbidity Among Patients With Multiple Sclerosis in a Large US Commercially Insured and Medicare Advantage Population by Dingwei Dai, Ajay Sharma, Amy L. Phillips, Carroline Lobo

“…Medicare Advantage patients were older (age <65: 53.3 [7.9]; age ≥65: 70.8 [5.2]) vs commercial (age, 45.7 [10.2]), had greater comorbidity burden (Charlson Comorbidity Index; age <65: 1.17 [1.64], age ≥65: 1.65 [1.95]) vs commercial (0.53 [1.02]) (all _P_ < .0001). Symptoms specific to MS (ie, malaise, fatigue, depression, spasms, fibromyalgia, convulsions) were more common among patients younger than 65 (all _P_ < .0001). …”
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Risk prediction models for dysphagia after radiotherapy among patients with head and neck cancer: a systematic review and meta-analysis by You Pu, Jin Yang, Lian Shui, Qianlong Tang, Xianqin Zhang, Guangguo Liu

“…However, all studies were considered to have a high risk of bias based on PROBAST assessments. …”
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Competency in Chest Radiography Interpretation by Junior Doctors and Final Year Medical Students at a Teaching Hospital by Bashiru Babatunde Jimah, Anthony Baffour Appiah, Benjamin Dabo Sarkodie, Dorothea Anim

“…We found a gap in doctors’ and medical students’ ability to interpret CXRs; hence, the development of this skill should be improved at all levels of medical training.…”
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Provision of dementia-specific care in nursing homes in North Rhine-Westphalia (Germany) – analysis of person-centered practices and related problems within a holistic multiple cas... by Kathrin Schmüdderich, Anne Fahsold, Jonas Dörner, Martina Roes, Rebecca Palm, Bernhard Holle

“…Even though the problems were identified in all cases, we also found differences in the extent and perception of these problems across the analyzed cases. …”
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Contextualization of Trait Nexus and Gene Action for Quantitative and Qualitative Characteristics in Indian Mustard by Sumanta Prasad Chand, Sandip Debnath, Mehdi Rahimi, Mohd. Shaikhul Ashraf, Pankaj Bhatt, Saima Ahmed Rahin

“…The findings suggested that there was substantial genetic variation for all traits examined. The mean oil yield of R1 B2-26 × R1 B2-25, JD6 × R1 B2-25, and JD6 × R1 B2-29 hybrids was more significant than that of the ancestors. …”
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A Randomized Clinical Trial of a Functional Electrical Stimulation Mimic to Gait Promotes Motor Recovery and Brain Remodeling in Acute Stroke by Xiuyuan Zheng, Danfeng Chen, Tiebin Yan, Dongmei Jin, Zhiqiang Zhuang, Zhimei Tan, Wei Wu

“…Brain fMRI were acquired before and after the intervention. All of the motor assessment scores significantly increased week by week in all the three groups. …”
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The Impact of Teacher Training on The Academic Performance of Student's Among Secondary Schools in Mbarara District: A Case Study of Kashari County Uganda. by Amumpaire, Catherine

“…This study would be very important to educational institutions all over the country, county, governments, the Ministry of Education (MoE), educational policymakers, school boards of management, and school head teachers and also form a baseline for further research…”
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The Impact of Teacher Training on The Academic Performance of Student's Among Secondary Schools in Mbarara District: A Case Study of Kashari County Uganda. by Amumpaire, Catherine

“…This study would be very important to educational institutions all over the country, county, governments, the ministry of Education (MoE), educational policymakers, school boards of management, and school head teachers and also form a baseline for further research…”
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