CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding by Qihong Yang, Liangyu Cai, Mila Wang, Guiyun Gan, Weiliu Li, Wenjia Li, Yaqin Jiang, Qi Yuan, Chunchun Qin, Chuying Yu, Yikui Wang

“…We generated single and double gene knockout mutants utilizing the tomato genetic transformation system. The fruit firmness of all knockout mutants exhibited a significant enhancement, with the most pronounced improvement observed in the double mutant. …”
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Anaemia Associated with Trypanosomes Infections in Cattle of West Gojjam Zone, Northwest Ethiopia by Kumela Lelisa, Behablom Meharenet

“…Trypanosoma congolense (4.25%) and T. vivax (3.56%) were the trypanosomes species identified in the studied area. PCV for all sampled cattle was analysed to estimate the degree of anaemia. …”
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Does abortion increase women's risk for post-traumatic stress? Findings from a prospective longitudinal cohort study by M Antonia Biggs, Charles E McCulloch, Brenly Rowland, Diana G Foster

“…PTSS, PTSD risk and pregnancy-related PTSS declined over time for all study groups.Conclusions Women who received an abortion were at no higher risk of PTSD than women denied an abortion.…”
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Generic, specific and direct object of a crime under the Article 330 of the Criminal Code of Ukraine by V. Yu. Boichuk

“…The link element through which the system of objects of this crime is formed is defined as the general sphere of social activity, where the mentioned social relations arise, develop and operate, namely, the national security of Ukraine. Thus, all social relations, which are put under the protection of Section XIV of the Special Part of the Criminal Code of Ukraine, arise and function in general in order to safeguard the interests of Ukraine’s national security. …”
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Anti-Obesity Effects of Arum maculatum, Nasturtium officinale Plant Extracts and Exercise in High Fat Diet-Induced Obese Rats by Zana Hassan Ibrahim

“…The NC group fed with normal diet (ND) and all other groups a high fat diet (HFD) to induce obesity and hyperlipidemia for 8 weeks. …”
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Protocol for evaluating the activity of R2 retrotransposons in mammalian cells by Yangcan Chen, Shengqiu Luo, Yanping Hu, Qi Zhou, Wei Li

“…Summary: R2 retrotransposons can be harnessed to insert genes at targeted sites by all-RNA delivery, presenting a new technology for next-generation biotherapeutics. …”
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Active Ingredients and Potential Mechanism of Additive Sishen Decoction in Treating Rheumatoid Arthritis with Network Pharmacology and Molecular Dynamics Simulation and Experimenta... by Ren J, Liu Z, Qi X, Meng X, Guo L, Yu Y, Dong T, Li Q

“…The binding mode between the key ingredients and key targets was elucidated using molecular docking and molecular dynamics simulation.Results: In all, 75 ASSD active ingredients and 1258 RA targets were analyzed, of which kaempferol, luteolin, and quercetin were considered key components that mainly act through inflammation-related pathways, such as the PI3K-AKT, TNF, and IL-17 signaling pathways, to ameliorate RA. …”
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Estimation for Reduction Potential Evaluation of CO₂ Emissions from Individual Private Passenger Cars Using Telematics by Masahiro Mae, Ziyang Wang, Shoma Nishimura, Ryuji Matsuhashi

“…CO₂ emissions from individual private passenger cars in 24 car models are estimated by the machine learning model based on random forest regression using data from telematics, and the coefficient of determination for all 24 car models is <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mi mathvariant="normal">R</mi><mn>2</mn></msup><mo>=</mo><mn>0.981</mn></mrow></semantics></math></inline-formula>. …”
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Effect of epigallocatechin-3-gallate (EGCG) on cognitive functioning and the expression of APP and BDNF in the hippocampus of rats with streptozotocin -induced Alzheimer-like disea... by Farnaz Ghayour Babaei, Ehsan Saburi, Fatemeh Forouzanfar, Mohadese Asgari, Zakieh Keshavarzi, Vahid Hajali

“…STZ disrupted the function of animals in MWM acquisition phase by almost 65 % and all doses of EGCG could return the learning parameters to those of control animals. …”
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Interventions promoting recovery from depression for patients transitioning from outpatient mental health services to primary care: A scoping review. by Anne Sofie Aggestrup, Frederik Martiny, Line Lund Henriksen, Annette Sofie Davidsen, Klaus Martiny

“…The studies had high heterogeneity in design, methods, sample size, recovery rating scales, and type of interventions. All studies used several elements in their interventions; however, the majority used cognitive behavioural therapy conducted in outpatient mental health services. …”
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Decreasing viscosity and increasing accessible load by replacing classical diluents with a hydrotrope in liquid–liquid extraction by Asmae El Maangar, Thomas Zemb, Clément Fleury, Jean Duhamet, Jean-François Dufrêche, Stéphane Pellet-Rostaing

“…The latter also quench all types of third-phase transition that occur when classical diluents are used. …”
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Human Tyrosinase Displayed on the Surface of Chinese Hamster Ovary Cells for Ligand Fishing of Tyrosinase Inhibitors from Medicinal Plants by Xiao-Rui Zhai, Ming-Jie Li, Xiang Yin, Ayzohra Ablat, Yuan Wang, Peng Shu, Xun Liao

“…Guided by the proposed ligand fishing method, four tyrosinase inhibitors, including 4-methoxy-5-methyl coumarin (<b>1</b>), cupressuflavone (<b>2</b>), amentoflavone (<b>3</b>), and 3,4-dimethoxy-5-methyl coumarin (<b>4</b>), were isolated from <i>Alhagi sparsifolia</i>, and the active fraction with low polarity was isolated from <i>Coffea arabica</i>; these two medicinal plants possess skin-lightening potential. All the isolated tyrosinase inhibitors significantly reduced the intracellular tyrosinase activity and melanin level in B16 cells enhanced by α-MSH. …”
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Effect of Cell Growth and Proliferation Factors (EGF/PDGF Signaling Pathway) on the Etiopathogenesis of Intrauterine Growth Restriction by Serhan Can İşcan, Erhan Demirdağ, Melek Yaman, Emin Ümit Bağrıacık, Merih Bayram

“…This study differs from previous IUGR studies, which focused on one or a few genes, because all the gene groups in the EGF/PDGF pathway that may be associated with IUGR were investigated.…”
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Evaluation of Sociodemographic Factors among Diabetic Patients with Urinary Tract Infections in Kisii Referral Hospital, Kenya by Vincent M. Mageto, Oliver W. Mbuthia, Caroline J. Ngetsa, Dinah O. Moraa, Erick O. Okoyo, Scholastica G. Mathenge, Wachuka G. Njoroge

“…Clean-catch midstream urine was collected from all participants and cultured in cysteine lactose electrolyte deficient agar for bacterial isolation. …”
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Pilot Trial of the Reboot Online Program: An Internet-Delivered, Multidisciplinary Pain Management Program for Chronic Pain by Regina Schultz, Jessica Smith, Jill M. Newby, Tania Gardner, Christine T. Shiner, Gavin Andrews, Steven G. Faux

“…Twenty participants experiencing pain of at least three months duration were recruited. All participants were enrolled in the “Reboot Online” program, consisting of eight online lessons completed over 16 weeks. …”
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Isokinetic Assessment of Knee Flexor and Extensor Strength and Lower Extremity Flexibility Assessment of an NCAA Division III Men’s Soccer Team by Savanna Perkins, Paul Canavan

“…Paired sample t-tests were used to compare left and right lower extremities for all outcomes, with the level of significance set at p\<0.05. …”
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Eating Habits, Anxiety and Depression in Patients with Irritable Bowel Syndrome: Clinical and Laboratory Comparisons by O. V. Gaus, M. A. Livzan

“…The control group included 40 healthy volunteers. All individuals included in the study were assessed for diet and eating habits using the WHO CINDI program questionnaire, “Information on Nutrition and Eating Behavior”, the severity of anxiety and depression according to the HADS questionnaire, the level of specific anxiety in relation to gastrointestinal symptoms according to the VSI questionnaire, quality of life according to the IBS-QoL questionnaire. …”
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Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis by Nicola Bizzaro, Franco Franceschini, Maria Infantino, Carlo Selmi, Gian Domenico Sebastiani, Francesca Motta, Davide Giavarina, Boaz Palterer

“…The main objective of this study is to provide an analysis of the literature on the role of RF isotypes in the diagnosis and prognosis of rheumatoid arthritis (RA).Methods We performed a systematic literature review and meta-analysis on the role of RF isotypes in RA (only in English, from PubMed, search terms: “rheumatoid factor isotypes”, “diagnosis”, “prognosis” and “rheumatoid arthritis”, last search 31 July 2022, two independent assessment of quality and biases, results included in tables and in the meta-analysis).Results Thirty-six articles were examined (7517 patients). Testing all RF isotypes with latex test or nephelometry allows for the highest sensitivity (68.6%, 95% CI 66.2% to 71.0%); nonetheless, the determination of IgA isotype provides the highest specificity (91.4%, 95% CI 90.8% to 92.0%) and the highest positive likelihood ratio (7.7, 95% CI 5.7 to 10.4). …”
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Numerical study of the plasticity effect on the behavior of short steel columns filled with concrete loaded axially by Yousria Boulmaali-Hacene Chaouche, Nadia Kouider, Kamel Djeghaba, Bachir Kebaili

“…The compressive behavior, including ultimate loads, confinement, load-deflection relationship and failure modes, was obtained from numerical models and compared with experimental and theoretical results based on Eurocode 4. All these results showed a good agreement and a satisfactory correlation, allowing us to assume that a correct modelling can be sufficient to simulate the behavior of CFST. …”
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Evaluating the impact of COVID-19 protection measures and staff absence on radiotherapy practice: A simulation study. by Elisabeth Jambor, Joe Viana, Melanie Reuter-Oppermann, Ralf Müller-Polyzou

“…COVID-19 protection measures reduce patient throughput. In all scenarios, with reduced patient throughput, follow-up radiation appointments were affected.…”
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